Page last updated: 2024-08-16

saccharin and morphine

saccharin has been researched along with morphine in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (33.33)	18.7374
1990's	23 (24.73)	18.2507
2000's	15 (16.13)	29.6817
2010's	21 (22.58)	24.3611
2020's	3 (3.23)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Campillo, NE; Guerra, A; Páez, JA	1
Cappell, H; Poulos, CX	1
Horowitz, GP; Smith, JC; Stephan, FK; Whitney, G	1
Fibiger, HC; Roberts, DC	1
Horowitz, GP; Whitney, G	1
Eikelboom, R; Stewart, J	1
Goudie, AJ; Thornton, EW; Wheller, TJ	1
Cappell, H; Herling, S; LeBlanc, AE	1
Pilcher, CW; Stolerman, IP	1
Touzani, K; Velley, L	2
Calcagnetti, DJ; Holtzman, SG	1
Pournaghash, S; Riley, AL; Stevenson, GW	1
Liebeskind, JC; Lieblich, I; Yirmiya, R	1
Akarid, K; Touzani, K; Velley, L	1
Babbini, M; Bacchi, A; Bartoletti, M; Costa, M; Gaiardi, M; Gubellini, C	1
Gans, M; Martin, GM; van der Kooy, D	1
Belknap, JK	1
Lieblich, I; Yirmiya, R	1
Alexander, BK; Beyerstein, BL; Forgie, ML	1
Bechara, A; Martin, GM; van der Kooy, D	1
Green, KF; Klein, SP	1
Blass, EM; Kehoe, P	1
Amit, Z; Hunt, T; Spivak, K	2
Amit, Z; Ng Cheong Ton, JM	2
Bergmann, F; Cohen, E; Ganchrow, JR; Lieblich, I	1
Cappell, H; LeBlanc, AE	1
Cappell, H; Endrenyi, L; LeBlanc, AE	1
Coussens, WR; Crowder, WF; Davis, WM	1
Failor, A; Parker, L; Weidman, K	1
Jacquet, YF	1
Bergmann, F; Cohen, E; Lieblich, I	2
Libby, L; Lynch, WC	1
Cooper, SJ	1
Calcagnetti, DJ; Reid, LD	1
Amit, Z; Ton, JM	1
Bergmann, F; Blass, EM; Cohen, E; Ganchrow, JR; Lieblich, I	1
Gibbs, GL; Mickley, GA; Stevens, KE; White, GA	1
Moroz, I; Parker, LA; Siegel, S	1
Bell, SM; Gosnell, BA; Krahn, DD; Lane, KE	1
Bardo, MT; Valone, JM	1
Jaeger, TV; van der Kooy, D	1
Moufid-Bellancourt, S; Velley, L	1
Bowers, RL; Falb, DC; Nicastle, LD	1
Cohen, E; Gagin, R; Shavit, Y	1
D'Anci, KE; Kanarek, RB; Marks-Kaufman, R	1
Järbe, TU; Lamb, RJ	2
Abdollahi, M; Etemad, F; Nikfar, S; Sharifzadeh, M	1
Bartoletti, M; Gaiardi, M; Gubellini, C	1
Abdollahi, M; Etemad, F; Nikfar, S; Sarkarati, F	1
D'Anci, KE	1
Grigson, PS; Lyuboslavsky, P; Tanase, D	1
Gomez, F; Grigson, PS; Leo, NA	1
McNally, GP; Westbrook, RF	1
Homoleski, B; Kanarek, RB	1
Abdollahi, M; Habibi, L; Nikfar, S	1
Calderon, SN; Hutchinson, AC; Randall, JF; Rice, KC; Riley, AL; Simpson, GR; Zhang, X	1
Boyce, JM; Risinger, FO	1
Randall-Thompson, JF; Riley, AL	1
Foynes, MM; Riley, AL	1
Flores, P; Glowa, J; Lopez-Grancha, M; Myracle, A; Riley, AL	1
Grigson, PS; Hajnal, A	1
Gomez-Serrano, MA; Kearns, DN; Riley, AL	1
Di Chiara, G; Fenu, S; Rivas, E	1
Reilly, S; Roman, C	1
Cadoni, C; Di Chiara, G; Fenu, S	1
Arthurs, J; Lin, JY; Reilly, S	1
Amodeo, LR; Arthurs, J; Lin, JY; Reilly, S	1
Hurwitz, ZE; Merluzzi, AP; Riley, AL	1
Alexander, DN; Grigson, PS; Liang, NC; Nyland, JE	1
Grigson, PS; Nyland, JE	1
Carroll, ME; Gewirtz, JC; Holtz, NA; Radke, AK	1
King, HE; Riley, AL	1
Freet, CS; Grigson, PS; Leuenberger, E; Mosblech, NA; Wheeler, RA	1
Cobuzzi, JL; Hurwitz, ZE; Merluzzi, AP; Riley, AL; Wetzell, B	1
Ardid, D; Etienne, M; Grégoire, S; Marchand, F; Wattiez, AS	1
Cadoni, C; Di Chiara, G; Espa, E; Fenu, S	1
Carroll, ME; Harris, AC; Holtz, NA; Radke, AK; Zlebnik, NE	1
Huang, AC; Wang, CC; Wang, S	1
Freet, CS; Grigson, PS; Reich, CG; Tompers, DA; Twining, RC; Wheeler, RA; Wolpert, SE	1
Jiang, C; Ma, L; Shen, M; Wang, F; Wang, L	1
Dasalla, J; Grigson, PS; Jenney, CB	1
Eastwood, EC; Eshleman, AJ; Janowsky, A; Phillips, TJ	1
Bohn, LM; Cameron, M; Grim, TW; Laprairie, RB; Park, SJ; Schmid, CL	1
Guenther, KG; Limebeer, CL; Parker, LA; Rock, EM; Wideman, CE	1
Cheng, CN; Chih Wei Huang, A; Chiu, WC; Lee, C; Wang, YC	1
Cerveny, SE; Davidson, TL; Huang, S; Riley, AL; Ruprecht, AL; Steere, ER	1
Davidson, TL; Ghasem Ardabili, N; Huang, S; Riley, AL	1

Other Studies

93 other study(ies) available for saccharin and morphine

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Associative factors in drug pretreatment effects on gustatory conditioning: cross-drug effects. Psychopharmacology, 1979, Aug-08, Volume: 64, Issue:2 Topics: Animals; Conditioning, Operant; Dextroamphetamine; Male; Morphine; Rats; Reinforcement Schedule; Saccharin; Taste	1979
Morphine ingestion: genetic control in mice. Psychopharmacology, 1977, Apr-29, Volume: 52, Issue:2 Topics: Animals; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Saccharin; Self Administration; Species Specificity; Time Factors	1977
Lesions of the dorsal noradrenergic projection attenuate morphine- but not amphetamine-induced conditioned taste aversion. Psychopharmacology, 1977, Dec-19, Volume: 55, Issue:2 Topics: Animals; Brain Chemistry; Conditioning, Psychological; Dextroamphetamine; Hydroxydopamines; Male; Morphine; Norepinephrine; Rats; Saccharin; Stereotaxic Techniques; Taste	1977
Morphine preference of alcohol-avoiding and alcohol-preferring C57BL mice. Behavior genetics, 1978, Volume: 8, Issue:2 Topics: Alcohol Drinking; Animals; Drinking Behavior; Genotype; Male; Mice; Mice, Inbred C57BL; Morphine; Saccharin	1978
Pre-exposure to morphine and the attenuation of conditioned taste aversion in rats. Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:5 Topics: Analgesics; Animals; Avoidance Learning; Drug Tolerance; Male; Morphine; Rats; Saccharin; Taste	1978
Drug pretreatment effects in drug induced taste aversions: effects of dose and duration of pretreatment. Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:5 Topics: Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking Behavior; Female; Fenfluramine; Methamphetamine; Morphine; p-Chloroamphetamine; Rats; Saccharin; Taste; Time Factors; Water Deprivation	1976
Modification of the punishing effects of psychoactive drugs in rats by previous drug experience. Journal of comparative and physiological psychology, 1975, Volume: 89, Issue:4 Topics: Animals; Association Learning; Avoidance Learning; Chlordiazepoxide; Conditioning, Operant; Dextroamphetamine; Drinking Behavior; Drug Tolerance; Habituation, Psychophysiologic; Male; Morphine; Rats; Saccharin	1975
Conditioned flavor aversions for assessing precipitated morphine abstinence in rats. Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:2 Topics: Animals; Male; Morphine; Naloxone; Rats; Saccharin; Taste	1976
Ibotenic acid lesion of the hypothalamic paraventricular nucleus produces weight gain but modifies neither preference nor aversion for saccharin. Physiology & behavior, 1992, Volume: 52, Issue:4 Topics: Animals; Avoidance Learning; Brain Mapping; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Ibotenic Acid; Male; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Saccharin; Sensory Thresholds; Taste; Water Deprivation; Weight Gain	1992
Intake of sweet water attenuates restraint-stress-induced potentiation of morphine analgesia in rats. Brain research bulletin, 1992, Volume: 29, Issue:6 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drinking; Drug Synergism; Glucose; Morphine; Pain; Rats; Rats, Sprague-Dawley; Restraint, Physical; Saccharin; Stress, Psychological; Sweetening Agents; Time Factors	1992
Antagonism of drug discrimination learning within the conditioned taste aversion procedure. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1 Topics: Animals; Avoidance Learning; Conditioning, Operant; Discrimination Learning; Female; Morphine; Naloxone; Rats; Saccharin; Taste	1992
Intake of and preference for sweet solutions are attenuated in morphine-withdrawn rats. Behavioral neuroscience, 1991, Volume: 105, Issue:6 Topics: Animals; Drinking; Drug Tolerance; Endorphins; Female; Food Preferences; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Saccharin; Substance Withdrawal Syndrome; Taste	1991
Modulation of saccharin preference by morphine and naloxone: inversion of drug effects as a function of saccharin concentration. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:1 Topics: Animals; Choice Behavior; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Saccharin; Water Deprivation	1991
Role of repeated exposure to morphine in determining its affective properties: place and taste conditioning studies in rats. Psychopharmacology, 1991, Volume: 103, Issue:2 Topics: Animals; Conditioning, Operant; Emotions; Male; Morphine; Rats; Rats, Inbred Strains; Saccharin; Taste	1991
Discriminative properties of morphine that modulate associations between tastes and lithium chloride. Journal of experimental psychology. Animal behavior processes, 1990, Volume: 16, Issue:1 Topics: Animals; Association Learning; Avoidance Learning; Chlorides; Conditioning, Classical; Discrimination Learning; Dose-Response Relationship, Drug; Drinking; Injections, Intraperitoneal; Learning; Lithium; Lithium Chloride; Male; Morphine; Motivation; Rats; Rats, Inbred Strains; Saccharin; Taste	1990
Physical dependence induced by the voluntary consumption of morphine in inbred mice. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:2 Topics: Animals; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Morphine Dependence; Naloxone; Reinforcement, Psychology; Saccharin; Self Administration; Species Specificity	1990
Ibotenic acid lesion of the lateral hypothalamus increases preference and aversion thresholds for saccharin and alters the morphine modulation of taste. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:3 Topics: Animals; Food Preferences; Hypothalamic Area, Lateral; Ibotenic Acid; Male; Morphine; Oxazoles; Rats; Rats, Inbred Strains; Saccharin; Sensory Thresholds; Taste	1990
Naltrexone reverses a long term depressive effect of a toxic lithium injection on saccharin preference. Physiology & behavior, 1987, Volume: 39, Issue:4 Topics: Animals; Chlorides; Female; Lithium; Lithium Chloride; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Saccharin; Taste	1987
Contributions of taste factors and gender to opioid preference in C57BL and DBA mice. Psychopharmacology, 1988, Volume: 95, Issue:2 Topics: Animals; Choice Behavior; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Saccharin; Sex Factors; Species Specificity; Taste	1988
Morphine preexposure attenuates the aversive properties of opiates without preexposure to the aversive properties. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3 Topics: Animals; Conditioning, Psychological; Male; Morphine; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Reference Values; Saccharin; Taste	1988
Tolerance to morphine analgesia from brief exposure to a palatable solution. Brain research bulletin, 1988, Volume: 21, Issue:6 Topics: Animals; Drug Tolerance; Female; Glucose; Morphine; Pain; Rats; Rats, Inbred Strains; Saccharin; Taste	1988
Behaviorally functional opioid systems in infant rats: I. Evidence for olfactory and gustatory classical conditioning. Behavioral neuroscience, 1986, Volume: 100, Issue:3 Topics: Animals; Animals, Suckling; Brain; Conditioning, Classical; Cues; Endorphins; Morphine; Odorants; Rats; Rats, Inbred Strains; Saccharin; Smell; Taste	1986
Aversive stimulus properties of morphine: evaluation using the drug preexposure conditioned taste aversion paradigm. Behavioral and neural biology, 1985, Volume: 44, Issue:1 Topics: Animals; Avoidance Learning; Conditioning, Classical; Discrimination Learning; Dose-Response Relationship, Drug; Drinking Behavior; Generalization, Stimulus; Male; Morphine; Rats; Rats, Inbred Strains; Saccharin; Taste; Time Factors	1985
Further evaluation of morphine aversion: maintenance of a taste aversion using a low, nonaversive morphine dose. Behavioral and neural biology, 1985, Volume: 44, Issue:1 Topics: Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Morphine; Rats; Rats, Inbred Strains; Saccharin; Time Factors	1985
Acetaldehyde and morphine interaction in the preexposure conditioned taste aversion paradigm in the rat. Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2 Topics: Acetaldehyde; Animals; Avoidance Learning; Drug Interactions; Ethanol; Male; Morphine; Rats; Rats, Inbred Strains; Reward; Saccharin; Taste	1985
Influence of intake of sweet solutions on the analgesic effect of a low dose of morphine in randomly bred rats. Behavioral and neural biology, 1985, Volume: 44, Issue:3 Topics: Animals; Brain; Drug Tolerance; Endorphins; Female; Food Preferences; Hypothalamic Area, Lateral; Morphine; Rats; Saccharin; Self Stimulation; Taste	1985
Attenuation of punishing effects of morphine and amphetamine by chronic prior treatment. Journal of comparative and physiological psychology, 1974, Volume: 87, Issue:4 Topics: Amphetamine; Animals; Avoidance Learning; Conditioning, Psychological; Drug Tolerance; Humans; Male; Morphine; Punishment; Rats; Saccharin; Substance-Related Disorders; Taste	1974
Aversive conditioning by psychoactive drugs: effects of morphine, alcohol and chlordiazepoxide. Psychopharmacologia, 1973, Volume: 29, Issue:3 Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Psychological; Ethanol; Male; Morphine; Rats; Saccharin; Taste	1973
Morphine induced saccharin aversion in -methyltyrosine pretreated rats. Psychopharmacologia, 1973, Mar-16, Volume: 29, Issue:2 Topics: Animals; Drinking Behavior; Drug Interactions; Food Preferences; Male; Methyltyrosines; Morphine; Premedication; Rats; Saccharin; Solutions; Taste; Taste Disorders; Water	1973
Conditioned preferences in the rat with an unnatural need state: morphine withdrawal. Journal of comparative and physiological psychology, 1973, Volume: 82, Issue:2 Topics: Acetates; Animals; Appetite; Avoidance Learning; Conditioning, Psychological; Drinking Behavior; Female; Humans; Injections, Intraperitoneal; Morphine; Morphine Dependence; Rats; Saccharin; Substance Withdrawal Syndrome; Sucrose; Taste; Water	1973
Conditioned aversion during morphine maintenance in mice and rats. Physiology & behavior, 1973, Volume: 11, Issue:4 Topics: Animals; Avoidance Learning; Body Weight; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Rats; Saccharin; Substance Withdrawal Syndrome; Water	1973
Attenuation of ethanol-induced conditioned taste aversion by naloxazone: behavioral evidence for an opiate receptor-mediated morphine-ethanol interaction. Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2 Topics: Animals; Avoidance Learning; Conditioning, Classical; Ethanol; Morphine; Naloxone; Rats; Receptors, Opioid; Saccharin; Taste	1984
Biphasic effects of chronic saccharin intake on pain responses of healthy and diabetic rats of two genetically selected strains. Psychopharmacology, 1984, Volume: 82, Issue:3 Topics: Analgesia; Animals; Diabetes Mellitus, Experimental; Drug Tolerance; Female; Morphine; Pain; Rats; Saccharin; Sensory Thresholds; Streptozocin; Time Factors	1984
Effects of chronically elevated intake of different concentrations of saccharin on morphine tolerance in genetically selected rats. Physiology & behavior, 1984, Volume: 32, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Morphine; Nociceptors; Rats; Rats, Inbred Strains; Saccharin; Selection, Genetic; Sensory Thresholds	1984
Naloxone suppresses intake of highly preferred saccharin solutions in food deprived and sated rats. Life sciences, 1983, Nov-07, Volume: 33, Issue:19 Topics: Animals; Dose-Response Relationship, Drug; Eating; Food Deprivation; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Saccharin; Satiation; Solutions	1983
Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat. Neuropharmacology, 1983, Volume: 22, Issue:3 Topics: Animals; Choice Behavior; Drinking Behavior; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Saccharin	1983
Morphine and acceptability of putative reinforcers. Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:4 Topics: Aging; Animals; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Saccharin	1983
Symmetrical effect of pre-exposure between alcohol and morphine on conditioned taste aversion. Life sciences, 1983, Aug-15, Volume: 33, Issue:7 Topics: Animals; Conditioning, Psychological; Ethanol; Kinetics; Male; Morphine; Rats; Rats, Inbred Strains; Saccharin; Taste; Water Deprivation	1983
Morphine tolerance in genetically selected rats induced by chronically elevated saccharin intake. Science (New York, N.Y.), 1983, Aug-26, Volume: 221, Issue:4613 Topics: Animals; Drug Tolerance; Endorphins; Morphine; Pain; Rats; Saccharin; Stress, Physiological	1983
Changes in morphine self-administration after exposure to ionizing radiation: evidence for the involvement of endorphins. Life sciences, 1983, Aug-22, Volume: 33, Issue:8 Topics: Animals; Cobalt Radioisotopes; Drinking Behavior; Endorphins; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Saccharin; Solutions	1983
Morphine-induced taste avoidance is attenuated with multiple conditioning trials. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2 Topics: Animals; Avoidance Learning; Conditioning, Operant; Lithium Chloride; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Taste	1995
Intravenous morphine self-administration by rats with low versus high saccharin preferences. Psychopharmacology, 1995, Volume: 117, Issue:2 Topics: Administration, Oral; Animals; Injections, Intravenous; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Self Administration; Taste	1995
Morphine-conditioned analgesia using a taste cue: dissociation of taste aversion and analgesia. Psychopharmacology, 1994, Volume: 114, Issue:2 Topics: Analgesia; Animals; Avoidance Learning; Cues; Dose-Response Relationship, Drug; Lithium; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Saccharin; Taste	1994
Morphine acts in the parabrachial nucleus, a pontine viscerosensory relay, to produce discriminative stimulus effects. Psychopharmacology, 1993, Volume: 110, Issue:1-2 Topics: Animals; Brain; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Microinjections; Morphine; Nucleus Accumbens; Pons; Rats; Rats, Wistar; Reinforcement, Psychology; Saccharin	1993
Effects of morphine injection into the parabrachial area on saccharin preference: modulation by lateral hypothalamic neurons. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1 Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drinking; Food Preferences; Hypothalamic Area, Lateral; Ibotenic Acid; Injections; Male; Morphine; Pons; Rats; Rats, Sprague-Dawley; Saccharin; Taste	1994
Saccharin effects on morphine-induced temperature change in rats. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2 Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Male; Morphine; Rats; Saccharin	1993
Prenatal exposure to morphine alters analgesic responses and preference for sweet solutions in adult rats. Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:4 Topics: Analgesics, Opioid; Animals; Delayed-Action Preparations; Female; Food Preferences; Male; Morphine; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Reaction Time; Saccharin; Sweetening Agents; Taste	1996
Beyond sweet taste: saccharin, sucrose, and polycose differ in their effects upon morphine-induced analgesia. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:3 Topics: Analgesics, Opioid; Animals; Body Composition; Drinking Behavior; Drug Evaluation, Preclinical; Drug Interactions; Energy Intake; Glucans; Male; Morphine; Pain Measurement; Rats; Saccharin; Sucrose; Taste; Time Factors	1997
Multielemental stimulus control: effects of saccharin concentration on a discriminated morphine-saccharin taste aversion. Experimental and clinical psychopharmacology, 1997, Volume: 5, Issue:2 Topics: Animals; Avoidance Learning; Discrimination Learning; Dose-Response Relationship, Drug; Lithium; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste	1997
Effects of sweetening agents on morphine-induced analgesia in mice by formalin test. General pharmacology, 1997, Volume: 29, Issue:4 Topics: Animals; Aspartame; Male; Mice; Morphine; Pain Measurement; Pain Threshold; Saccharin; Sucrose; Sweetening Agents	1997
Taste conditioning effects of buprenorphine in morphine-naive and morphine-experienced rats. Pharmacological research, 1998, Volume: 37, Issue:4 Topics: Analgesics, Opioid; Animals; Appetite Depressants; Buprenorphine; Conditioning, Operant; Dextroamphetamine; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste	1998
Interaction between calcium channel blockers and sweetening agents on morphine-induced analgesia in mice by formalin test. General pharmacology, 1998, Volume: 31, Issue:3 Topics: Analgesics; Animals; Aspartame; Calcium Channel Blockers; Diltiazem; Drug Interactions; Male; Mice; Morphine; Nifedipine; Pain Measurement; Saccharin; Sucrose; Sweetening Agents; Verapamil	1998
Tolerance to morphine-induced antinociception is decreased by chronic sucrose or polycose intake. Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:1 Topics: Analgesics, Opioid; Animals; Body Weight; Drug Tolerance; Eating; Glucans; Male; Morphine; Pain; Rats; Rats, Long-Evans; Saccharin; Sucrose; Time Factors; Water	1999
Discriminated taste aversion and context: a progress report. Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:2 Topics: Animals; Antimanic Agents; Avoidance Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste	1999
Bilateral lesions of the gustatory thalamus disrupt morphine- but not LiCl-induced intake suppression in rats: evidence against the conditioned taste aversion hypothesis. Brain research, 2000, Mar-10, Volume: 858, Issue:2 Topics: Animals; Antimanic Agents; Avoidance Learning; Conditioning, Psychological; Denervation; Drinking; Excitatory Amino Acid Agonists; Ibotenic Acid; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste; Thalamus	2000
Morphine-induced suppression of saccharin intake is correlated with elevated corticosterone levels. Brain research, 2000, Apr-28, Volume: 863, Issue:1-2 Topics: Animals; Conditioning, Psychological; Corticosterone; Drug Interactions; Eating; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration; Stress, Physiological; Sweetening Agents; Taste	2000
Acute exposure to saccharin reduces morphine analgesia in the the rat: evidence for involvement of N-methyl-D-aspartate and peripheral opioid receptors. Psychopharmacology, 2000, Volume: 149, Issue:1 Topics: Analgesia; Analgesics, Opioid; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Saccharin; Sweetening Agents	2000
Modulation of morphine-induced antinociception by palatable solutions in male and female rats. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:3 Topics: Analgesics, Opioid; Animals; Body Weight; Diet; Female; Food-Drug Interactions; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Long-Evans; Saccharin; Sex Characteristics; Sucrose; Taste	2000
Saccharin effects on morphine-induced antinociception in the mouse formalin test. Pharmacological research, 2000, Volume: 42, Issue:3 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Saccharin; Sweetening Agents	2000
Assessment of SNC 80 and naltrindole within a conditioned taste aversion design. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4 Topics: Animals; Avoidance Learning; Benzamides; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Saccharin; Sweetening Agents; Taste	2000
Conditioning tastant and the acquisition of conditioned taste avoidance to drugs of abuse in DBA/2J mice. Psychopharmacology, 2002, Volume: 160, Issue:3 Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Ethanol; Illicit Drugs; Lithium; Male; Mice; Mice, Inbred DBA; Morphine; Saccharin; Sodium Chloride; Taste	2002
Morphine-induced conditioned taste aversions: assessment of sexual dimorphism. Pharmacology, biochemistry, and behavior, 2003, Volume: 76, Issue:2 Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Lithium Chloride; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Sex Characteristics; Sweetening Agents; Taste	2003
Lithium-chloride-induced conditioned taste aversions in the Lewis and Fischer 344 rat strains. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2 Topics: Animals; Cocaine; Conditioning, Psychological; Female; Lithium Chloride; Morphine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Saccharin; Species Specificity; Substance-Related Disorders; Sweetening Agents; Taste	2004
Differential effects of morphine and LiCl on schedule-induced polydipsia. Pharmacology, biochemistry, and behavior, 2005, Volume: 80, Issue:1 Topics: Animals; Conditioning, Psychological; Drinking Behavior; Female; Lithium Chloride; Morphine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Saccharin	2005
Once is too much: conditioned changes in accumbens dopamine following a single saccharin-morphine pairing. Behavioral neuroscience, 2007, Volume: 121, Issue:6 Topics: Animals; Behavior, Animal; Conditioning, Psychological; Dopamine; Male; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Time Factors	2007
The effects of light cycle phase on morphine-induced conditioned taste aversions in the Lewis, Fischer and Sprague-Dawley rat strains. Behavioural brain research, 2009, Jan-03, Volume: 196, Issue:1 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Avoidance Learning; Biological Clocks; Body Weight; Conditioning, Psychological; Dose-Response Relationship, Drug; Drinking; Injections, Subcutaneous; Morphine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Saccharin; Species Specificity; Sweetening Agents; Taste; Time Factors; Water Deprivation	2009
Differential involvement of dopamine D1 receptors in morphine- and lithium-conditioned saccharin avoidance. Physiology & behavior, 2009, Jan-08, Volume: 96, Issue:1 Topics: Animals; Avoidance Learning; Benzazepines; Conditioning, Operant; Dopamine Antagonists; Food Preferences; Lithium Chloride; Male; Morphine; Narcotics; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Saccharin; Time Factors; Water Deprivation	2009
Insular cortex lesions and morphine-induced suppression of conditioned stimulus intake in the rat. Behavioral neuroscience, 2009, Volume: 123, Issue:1 Topics: Animals; Behavior, Animal; Cerebral Cortex; Conditioning, Operant; Eating; Excitatory Amino Acid Agonists; Male; Morphine; N-Methylaspartate; Narcotics; Rats; Saccharin; Sweetening Agents; Taste	2009
Conditioned saccharin avoidance and sensitization to drugs of abuse. Behavioural brain research, 2010, Dec-25, Volume: 214, Issue:2 Topics: Amphetamine; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Illicit Drugs; Male; Morphine; Nicotine; Rats; Rats, Sprague-Dawley; Saccharin	2010
Role of the insular cortex in morphine-induced conditioned taste avoidance. Brain research, 2011, Apr-12, Volume: 1384 Topics: Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Classical; Excitatory Amino Acid Agonists; Male; Morphine; N-Methylaspartate; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste	2011
Reduced palatability in drug-induced taste aversion: II. Aversive and rewarding unconditioned stimuli. Behavioral neuroscience, 2012, Volume: 126, Issue:3 Topics: Amphetamine; Animals; Avoidance Learning; Conditioning, Psychological; Food Preferences; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sucrose; Taste	2012
Age-dependent differences in morphine-induced taste aversions. Developmental psychobiology, 2013, Volume: 55, Issue:4 Topics: Age Factors; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Classical; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste; Time Factors	2013
Bilateral lesions of the thalamic trigeminal orosensory area dissociate natural from drug reward in contrast paradigms. Behavioral neuroscience, 2012, Volume: 126, Issue:4 Topics: Analysis of Variance; Animals; Antimanic Agents; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Conditioning, Operant; Dopamine Uptake Inhibitors; Eating; Excitatory Amino Acid Agonists; Food Preferences; Ibotenic Acid; Lithium Chloride; Male; Morphine; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Saccharin; Taste; Thalamus	2012
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration. Behavioural brain research, 2013, Mar-01, Volume: 240 Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste	2013
Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Psychopharmacology, 2013, Volume: 227, Issue:1 Topics: Acoustic Stimulation; Analgesics, Opioid; Animals; Breeding; Emotions; Female; Male; Morphine; Morphine Dependence; Rats; Rats, Sprague-Dawley; Reflex, Startle; Saccharin; Substance Withdrawal Syndrome	2013
A history of morphine-induced taste aversion learning fails to affect morphine-induced place preference conditioning in rats. Learning & behavior, 2013, Volume: 41, Issue:4 Topics: Animals; Avoidance Learning; Conditioning, Classical; Morphine; Rats; Reward; Saccharin; Taste	2013
Fischer rats are more sensitive than Lewis rats to the suppressive effects of morphine and the aversive kappa-opioid agonist spiradoline. Behavioral neuroscience, 2013, Volume: 127, Issue:5 Topics: Analgesics, Opioid; Animals; Association Learning; Cues; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Opioid, kappa; Saccharin; Species Specificity; Sweetening Agents; Taste	2013
Prepubertal Fischer 344 rats display stronger morphine-induced taste avoidance than prepubertal Lewis rats. Developmental psychobiology, 2014, Volume: 56, Issue:5 Topics: Animals; Avoidance Learning; Conditioning, Psychological; Morphine; Narcotics; Rats; Rats, Inbred F344; Rats, Inbred Lew; Saccharin; Species Specificity; Taste	2014
Monoarthritis-induced emotional and cognitive impairments in rats are sensitive to low systemic doses or intra-amygdala injections of morphine. European journal of pharmacology, 2014, Jul-15, Volume: 735 Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Basolateral Nuclear Complex; Cognition; Cognition Disorders; Disease Models, Animal; Emotions; Food Preferences; Freund's Adjuvant; Hyperalgesia; Injections; Interpersonal Relations; Male; Maze Learning; Morphine; Pain; Rats, Sprague-Dawley; Saccharin	2014
Conditioned saccharin avoidance induced by infusion of amphetamine in the nucleus accumbens shell and morphine in the ventral tegmental area: behavioral and biochemical study. Behavioural brain research, 2014, Aug-01, Volume: 269 Topics: Amphetamine; Animals; Avoidance Learning; Brain; Conditioning, Psychological; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Eating; Illicit Drugs; Male; Morphine; Narcotics; Nucleus Accumbens; Rats, Sprague-Dawley; Saccharin; Space Perception; Ventral Tegmental Area	2014
Intracranial self-stimulation reward thresholds during morphine withdrawal in rats bred for high (HiS) and low (LoS) saccharin intake. Brain research, 2015, Mar-30, Volume: 1602 Topics: Animals; Animals, Outbred Strains; Electric Stimulation; Food Preferences; Genetic Predisposition to Disease; Implantable Neurostimulators; Male; Morphine; Naloxone; Narcotics; Random Allocation; Rats, Sprague-Dawley; Reward; Saccharin; Self Stimulation; Species Specificity; Substance Withdrawal Syndrome	2015
Examinations of the reward comparison hypothesis: The modulation of gender and footshock. Physiology & behavior, 2015, Nov-01, Volume: 151 Topics: Animals; Central Nervous System Stimulants; Conditioning, Psychological; Electroshock; Female; Foot; Illicit Drugs; Lithium Chloride; Male; Methamphetamine; Models, Psychological; Morphine; Motor Activity; Narcotics; Psychotropic Drugs; Random Allocation; Rats, Wistar; Reward; Saccharin; Sex Characteristics	2015
The role of dose and restriction state on morphine-, cocaine-, and LiCl-induced suppression of saccharin intake: A comprehensive analysis. Physiology & behavior, 2016, 07-01, Volume: 161 Topics: Animals; Antimanic Agents; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Eating; Food Deprivation; Food Preferences; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Vasoconstrictor Agents; Water Deprivation	2016
Parvalbumin Interneurons of Central Amygdala Regulate the Negative Affective States and the Expression of Corticotrophin-Releasing Hormone During Morphine Withdrawal. The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:11 Topics: Affect; Animals; Anxiety; Behavior, Animal; Central Amygdaloid Nucleus; Corticotropin-Releasing Hormone; Disease Models, Animal; Excitatory Postsynaptic Potentials; Feeding Behavior; Genotype; Interneurons; Maze Learning; Mice, Inbred C57BL; Mice, Transgenic; Miniature Postsynaptic Potentials; Morphine; Optogenetics; Parvalbumins; Phenotype; RNA, Messenger; Saccharin; Signal Transduction; Substance Withdrawal Syndrome; Up-Regulation	2016
Female rats exhibit less avoidance than male rats of a cocaine-, but not a morphine-paired, saccharin cue. Brain research bulletin, 2018, Volume: 138 Topics: Analysis of Variance; Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Corticosterone; Cues; Estrous Cycle; Female; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sex Characteristics; Taste	2018
Verification of a genetic locus for methamphetamine intake and the impact of morphine. Mammalian genome : official journal of the International Mammalian Genome Society, 2018, Volume: 29, Issue:3-4 Topics: Animals; Choice Behavior; Chromosomes, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Genetic Loci; Genetic Predisposition to Disease; Methamphetamine; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Reproducibility of Results; Saccharin; Tritium	2018
The effect of quinine in two bottle choice procedures in C57BL6 mice: Opioid preference, somatic withdrawal, and pharmacokinetic outcomes. Drug and alcohol dependence, 2018, 10-01, Volume: 191 Topics: Analgesics, Opioid; Animals; Brain; Choice Behavior; Male; Mice; Mice, Inbred C57BL; Morphine; Quinine; Saccharin; Substance Withdrawal Syndrome; Taste	2018
Conditioned aversive responses produced by delayed, but not immediate, exposure to cocaine and morphine in male Sprague-Dawley rats. Psychopharmacology, 2018, Volume: 235, Issue:11 Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Cues; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Taste; Time Factors	2018
Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters, 2021, 08-24, Volume: 760 Topics: Amygdala; Animals; Conditioning, Operant; Disease Models, Animal; Hippocampus; Humans; Interleukin-1beta; Male; Morphine; Morphine Dependence; Neuroinflammatory Diseases; Prefrontal Cortex; Rats; Reward; Saccharin; Signal Transduction	2021
Serial feature positive and feature negative discrimination learning in a taste avoidance preparation: implications for interoceptive control of behavior. Behavioural pharmacology, 2023, 09-01, Volume: 34, Issue:6 Topics: Animals; Avoidance Learning; Discrimination Learning; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Taste	2023
Western diet consumption does not impact the rewarding and aversive effects of morphine in male Sprague-Dawley rats. Physiology & behavior, 2023, 10-15, Volume: 270 Topics: Animals; Avoidance Learning; Diet, Western; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sugars; Taste	2023