Page last updated: 2024-08-16

saccharin and indomethacin

saccharin has been researched along with indomethacin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.00)29.6817
2010's13 (65.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
George, FR1
Basavoju, S; Boström, D; Velaga, SP1
Alhalaweh, A; Allesø, M; Cornett, C; de Diego, HL; Rantanen, J; Rasmussen, MA; van den Berg, F; Velaga, S1
de Azevedo, EG; Matos, HA; Padrela, L; Rodrigues, MA; Velaga, SP1
Alhalaweh, A; Cho, W; Hwang, SJ; Jung, MS; Kim, JS; Kim, MS; Velaga, SP1
de Azevedo, EG; Padrela, L; Velaga, SP1
Lin, HL; Lin, SY; Zhang, GC1
Alhalaweh, A; Rodríguez-Hornedo, N; Roy, L; Velaga, SP1
Choi, GJ; Chun, NH; Jung, YT; Kim, WS; Lee, MJ; Lee, S; Wang, IC1
Beggiato, S; Bertolasi, V; Dalpiaz, A; Ferraro, L; Ferretti, V; Pavan, B; Spisni, E; Spizzo, F1
Box, KJ; Comer, J; Fotaki, N; Karki, S; Price, R; Ruiz, R; Taylor, R1
Adibkia, K; Barzegar-Jalali, M; Emami, S; Siahi-Shadbad, M1
Garbacz, P; Wesolowski, M1
Ashizawa, K; Hattori, Y; Otsuka, M; Tanaka, R1
Kiguchiya, A; Sakane, T; Teraoka, R; Yonemochi, E1
Duggirala, NK; Hattori, Y; Otsuka, M; Suryanarayanan, R; Tanaka, R1
Higashi, K; Kosaka, M; Moribe, K; Nishimura, M; Ueda, K1
Cai, Y; Deng, X; Jing, P; Li, Y; Xu, G; Xu, L; Zhou, Q1

Other Studies

20 other study(ies) available for saccharin and indomethacin

ArticleYear
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
The role of arachidonic acid metabolites in mediating ethanol self-administration and intoxication.
    Annals of the New York Academy of Sciences, 1989, Volume: 559

    Topics: Alcoholic Intoxication; Animals; Arachidonic Acids; Ethanol; Indomethacin; Male; Rats; Rats, Inbred Strains; Saccharin; Self Administration

1989
Indomethacin-saccharin cocrystal: design, synthesis and preliminary pharmaceutical characterization.
    Pharmaceutical research, 2008, Volume: 25, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Design; Indomethacin; Kinetics; Models, Molecular; Molecular Structure; Powder Diffraction; Saccharin; Solubility; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Technology, Pharmaceutical; Volatilization

2008
Near-infrared spectroscopy for cocrystal screening. A comparative study with Raman spectroscopy.
    Analytical chemistry, 2008, Oct-15, Volume: 80, Issue:20

    Topics: Aspartic Acid; Crystallization; Indomethacin; Saccharin; Spectrophotometry, Infrared; Spectrum Analysis, Raman; X-Ray Diffraction

2008
Formation of indomethacin-saccharin cocrystals using supercritical fluid technology.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Aug-12, Volume: 38, Issue:1

    Topics: Calorimetry, Differential Scanning; Carbon Dioxide; Crystallization; Fourier Analysis; Indomethacin; Microscopy, Electron, Scanning; Particle Size; Pressure; Saccharin; Solvents; Spectrum Analysis, Raman; Surface Properties; Technology, Pharmaceutical; Temperature; X-Ray Diffraction

2009
Bioavailability of indomethacin-saccharin cocrystals.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:11

    Topics: Animals; Biological Availability; Capsules; Chemistry, Pharmaceutical; Crystallization; Dogs; Indomethacin; Lactose; Saccharin; Solubility

2010
Powder X-ray diffraction method for the quantification of cocrystals in the crystallization mixture.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:8

    Topics: Calibration; Calorimetry, Differential Scanning; Crystallization; Indomethacin; Powders; Reproducibility of Results; Saccharin; X-Ray Diffraction

2012
Thermal analysis and FTIR spectral curve-fitting investigation of formation mechanism and stability of indomethacin-saccharin cocrystals via solid-state grinding process.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 66

    Topics: Calorimetry, Differential Scanning; Crystallization; Drug Stability; Drug Storage; Hydrogen Bonding; Indomethacin; Saccharin; Solvents; Spectroscopy, Fourier Transform Infrared; Temperature; Time Factors; Transition Temperature

2012
pH-dependent solubility of indomethacin-saccharin and carbamazepine-saccharin cocrystals in aqueous media.
    Molecular pharmaceutics, 2012, Sep-04, Volume: 9, Issue:9

    Topics: Calorimetry, Differential Scanning; Carbamazepine; Crystallization; Hydrogen-Ion Concentration; Indomethacin; Models, Chemical; Powder Diffraction; Saccharin; Solubility; Water; X-Ray Diffraction

2012
Characteristics of indomethacin-saccharin (IMC-SAC) co-crystals prepared by an anti-solvent crystallization process.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt B

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Crystallization; Indomethacin; Methanol; Powders; Saccharin; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Water; X-Ray Diffraction

2013
Indomethacin co-crystals and their parent mixtures: does the intestinal barrier recognize them differently?
    Molecular pharmaceutics, 2015, May-04, Volume: 12, Issue:5

    Topics: Animals; Calorimetry, Differential Scanning; Cell Line; Chromatography, High Pressure Liquid; Crystallization; Humans; Indomethacin; Male; Rats; Rats, Sprague-Dawley; Saccharin; Solubility

2015
Small-Scale Assays for Studying Dissolution of Pharmaceutical Cocrystals for Oral Administration.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:2

    Topics: Administration, Oral; Biological Assay; Carbamazepine; Chemical Precipitation; Crystallization; Indomethacin; Niacinamide; Pharmaceutical Preparations; Saccharin; Solubility; Tablets

2016
Feasibility of electrospray deposition for rapid screening of the cocrystal formation and single step, continuous production of pharmaceutical nanococrystals.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:6

    Topics: Crystallization; Indomethacin; Niacinamide; Saccharin; Solvents; X-Ray Diffraction

2018
DSC, FTIR and Raman Spectroscopy Coupled with Multivariate Analysis in a Study of Co-Crystals of Pharmaceutical Interest.
    Molecules (Basel, Switzerland), 2018, Aug-24, Volume: 23, Issue:9

    Topics: 4-Aminobenzoic Acid; Calorimetry, Differential Scanning; Furosemide; Indomethacin; Pharmaceutical Preparations; Saccharin; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman

2018
Kinetics Study of Cocrystal Formation Between Indomethacin and Saccharin Using High-Shear Granulation With In Situ Raman Spectroscopy.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:10

    Topics: Calorimetry, Differential Scanning; Crystallization; Indomethacin; Kinetics; Saccharin; Solubility; Solvents; Spectrum Analysis, Raman; Tablets; Technology, Pharmaceutical; Temperature; Thermodynamics; X-Ray Diffraction

2019
A New Method for Classification of Salts and Cocrystals Using Solid-State UV Spectrophotometry.
    Chemical & pharmaceutical bulletin, 2019, Volume: 67, Issue:9

    Topics: Arginine; Crystallization; Indomethacin; Magnetic Resonance Spectroscopy; Meglumine; Saccharin; Salts; Spectrophotometry, Ultraviolet; X-Ray Diffraction

2019
Formation of Indomethacin-Saccharin Cocrystals during Wet Granulation: Role of Polymeric Excipients.
    Molecular pharmaceutics, 2020, 01-06, Volume: 17, Issue:1

    Topics: Cellulose; Crystallization; Ethanol; Excipients; Indomethacin; Kinetics; Polyethylene Glycols; Polymers; Povidone; Saccharin; Solubility; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction

2020
Clarification of the Dissolution Mechanism of an Indomethacin/Saccharin/Polyvinylpyrrolidone Ternary Solid Dispersion by NMR Spectroscopy.
    Journal of pharmaceutical sciences, 2020, Volume: 109, Issue:12

    Topics: Calorimetry, Differential Scanning; Indomethacin; Magnetic Resonance Spectroscopy; Povidone; Saccharin; Solubility

2020
Terahertz spectroscopic characterizations and DFT calculations of indomethacin cocrystals with nicotinamide and saccharin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Mar-15, Volume: 249

    Topics: Density Functional Theory; Indomethacin; Niacinamide; Saccharin; Solubility; Terahertz Spectroscopy

2021