Page last updated: 2024-08-16

saccharin and hydrochlorothiazide

saccharin has been researched along with hydrochlorothiazide in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's0 (0.00)18.2507
2000's1 (3.85)29.6817
2010's23 (88.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Cincinelli, A; Innocenti, A; Martellini, T; Scozzafava, A; Supuran, CT1
Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D1
Jackson, DJ; Ohradanova, A; Pastorek, J; Pastorekova, S; Supuran, CT; Vullo, D; Wörheide, G1
Capasso, C; Carginale, V; Luca, VD; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D1
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Isik, S; Scozzafava, A; Supuran, CT; Vullo, D1
Capaci Rodrigues, G; Capasso, C; Pan, P; Parkkila, S; Scozzafava, A; Supuran, CT; Tolvanen, ME; Vermelho, AB1
Capasso, C; Corte-Real, S; Pan, P; Parkkila, S; Rodrigues, Ide A; Salonen, T; Supuran, CT; Syrjänen, L; Vermelho, AB; Vullo, D1
Alothman, Z; Capasso, C; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D2
Capasso, C; Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Osman, SM; Prete, SD; Scozzafava, A; Supuran, CT; Vullo, D1
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Scozzafava, A; Supuran, CT; Vullo, D2
Kuuslahti, M; Parkkila, S; Supuran, CT; Syrjänen, L; Tolvanen, M; Vullo, D1
Capasso, C; Dedeoglu, N; DeLuca, V; Isik, S; Kockar, F; Supuran, CT; Yildirim, H1
Cincinelli, A; Martellini, T; Supuran, CT; Vullo, D1
Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Ferraroni, M; Osman, SM; Supuran, CT; Vullo, D1
Aşık, A; Beldüz, AO; Çanakçı, S; Çolak, DN; Eminoğlu, A; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Supuran, CT; Vullo, D1
Angeli, A; Berrino, E; Capasso, C; De Luca, L; Del Prete, S; Gitto, R; Mancuso, F; Supuran, CT1
Barofsky, I; Kresel, JJ1

Other Studies

26 other study(ies) available for saccharin and hydrochlorothiazide

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Animals; Anions; Antarctic Regions; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Protein Isoforms; Seals, Earless; Sulfonamides

2011
Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Salmonella Infections; Salmonella typhimurium; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2011
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.
    Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Animals; Carbonic Anhydrases; Cloning, Molecular; Fossils; Humans; Molecular Sequence Data; Porifera; Protein Binding; Sequence Alignment; Sulfonamides; Sulfonic Acids

2012
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides.
    Bioorganic & medicinal chemistry, 2013, Mar-15, Volume: 21, Issue:6

    Topics: Amino Acid Sequence; Bacteria; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Protein Binding; Recombinant Proteins; Sequence Alignment; Sulfonamides

2013
DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23

    Topics: Amino Acid Sequence; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Vibrio cholerae

2012
Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.
    Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chagas Disease; Cloning, Molecular; Humans; Molecular Sequence Data; Phylogeny; Protozoan Proteins; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonamides; Thiadiazoles; Trypanocidal Agents; Trypanosoma cruzi

2013
Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.
    Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18

    Topics: Amino Acid Sequence; Antiprotozoal Agents; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Leishmania infantum; Leishmaniasis; Molecular Sequence Data

2013
Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diatoms; Dose-Response Relationship, Drug; Molecular Structure; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.
    Bioorganic & medicinal chemistry, 2014, Jun-01, Volume: 22, Issue:11

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Legionella pneumophila; Molecular Sequence Data; Molecular Structure; Sequence Alignment; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes.
    Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Sequence Data; Molecular Structure; Phylogeny; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
    Bioorganic & medicinal chemistry, 2015, Apr-15, Volume: 23, Issue:8

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Sequence Data; Nostoc commune; Sequence Alignment; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines; Thiophenes

2015
The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Amino Acid Sequence; Animals; Anopheles; Baculoviridae; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Gene Expression; High-Throughput Screening Assays; Insect Proteins; Insecticides; Kinetics; Molecular Sequence Data; Phylogeny; Protons; Recombinant Proteins; Sequence Alignment; Sf9 Cells; Spodoptera; Sulfanilamides

2015
Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans.
    Bioorganic & medicinal chemistry letters, 2015, Jun-01, Volume: 25, Issue:11

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Molecular Structure; Phylogeny; Streptococcus mutans; Sulfonamides

2015
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Acclimatization; Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cold Temperature; Humans; Molecular Sequence Data; Phylogeny; Pseudoalteromonas; Sequence Alignment; Sulfonamides

2015
Anion and sulfonamide inhibition studies of an α-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Animals; Anions; Antarctic Regions; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Activation; Fishes; Molecular Structure; Sulfonamides

2015
Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Anti-Bacterial Agents; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gammaproteobacteria; Molecular Docking Simulation; Sulfonamides

2016
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Alteromonadaceae; Anti-Bacterial Agents; Bacterial Proteins; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Phylogeny; Protein Binding; Sulfanilamide; Sulfanilamides

2016
Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Bioorganic & medicinal chemistry, 2016, Mar-01, Volume: 24, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cholera; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Sulfonamides; Vibrio cholerae

2016
Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13.
    Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7

    Topics: Acetazolamide; Benzenesulfonamides; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Enterobacter; Enterobacteriaceae Infections; Humans; Methazolamide; Structure-Activity Relationship; Sulfonamides

2016
Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.
    Bioorganic & medicinal chemistry letters, 2016, Apr-15, Volume: 26, Issue:8

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Sulfonamides; Vibrio cholerae

2016
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in
    ACS medicinal chemistry letters, 2020, Nov-12, Volume: 11, Issue:11

    Topics:

2020
Conditioned saccharin aversion development following administration of hypotensive agents.
    Physiology & behavior, 1979, Volume: 23, Issue:4

    Topics: Animals; Antihypertensive Agents; Avoidance Learning; Conditioning, Classical; Drinking; Extinction, Psychological; Hydralazine; Hydrochlorothiazide; Male; Methyldopa; Rats; Saccharin; Taste

1979