Page last updated: 2024-08-16

saccharin and caffeine

saccharin has been researched along with caffeine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199017 (47.22)18.7374
1990's1 (2.78)18.2507
2000's4 (11.11)29.6817
2010's10 (27.78)24.3611
2020's4 (11.11)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Gilbert, RM1
Ardito, G; Brøgger, A; Waksvik, H1
Heffelfinger, GP; Ruggles, DI; Woodward, BB1
Vitiello, MV; Woods, SC1
Cole, P; Simon, D; Yen, S1
Conrad, EC; Smyly, DS; Woodward, BB1
Bean, NJ; Mason, JR1
Eckel, DL; O'Regan, MH; Rusiniak, KW; Steigerwald, ES1
Bantle, JA; Dawson, DA1
Bollack, C; Pusel, P; Schaffer, P1
Aimez, P; Dorf, G; Duchier, J; Guy-Grand, B1
Nakano, M1
Doornbos, DA; Rolink, H; Weyland, JW1
Ambrose, RB; Fernicola, AR; Louria, DB; Najem, GR; Prusakowski, JM; Seebode, JJ; Thind, IS1
Morgan, KJ; Stults, VJ; Zabik, ME1
Arai, M; Hagiwara, A; Ito, N; Miyata, Y; Murasaki, G; Nakatsuka, T1
Arai, M; Hasegawa, R; Hirose, M; Ito, N; Nakanishi, K; Ogiso, T1
Louis-Sylvestre, J; Smagghe, K1
Amit, Z; Bloch, RT; Kunin, D; Rogan, F; Smith, BR; Terada, Y1
Chapman, CD; Dess, NK; Garrett, C; Gonzales, M1
Alcolado, GM; Dingle, RN; Dreumont-Boudreau, SE; Lolordo, VM1
Clark, KM; Davidson, TL; Laboy, AF; Martin, AA; Swithers, SE1
Chen, X; Jin, M; Li, X; Yao, S; Zhao, Y1
Dong, P; Huang, Z; Lang, T; Li, Y; Lin, L; Lu, M; Wu, C1
Huang, L; Malach, E; Naim, M; Peri, I; Seger, R; Shaul, ME; Spielman, AI1
Ciosek, P; del Valle, M; Gonzalez-Calabuig, A; Kirsanov, D; Legin, A; Pein, M; Wesoły, M; Wróblewski, W; Yaroshenko, I; Zabadaj, M1
McRoberts, CW; Paterson, E; Richards, S; Stutter, M; Withers, PJA1
Gramling, L; Kapoulea, E; Murphy, C1
Bradley, CA; Palmatier, MI1
Boakes, RA; Farabi, L; Rehn, S1
Amé, MV; Carrizo, JC; Marconi, G; Munoz, G; Sauvé, S; Vo Duy, S1
Diniz, V; Rath, S1
Bak, S; Kim, DG; Kim, HD; Kim, SW; Lee, MW; Lee, SJ; Lim, DJ; Park, SY1

Other Studies

36 other study(ies) available for saccharin and caffeine

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Dietary caffeine and alcohol consumption by rats.
    Journal of studies on alcohol, 1976, Volume: 37, Issue:1

    Topics: Alcohol Drinking; Animals; Caffeine; Drug Interactions; Male; Nutrition Disorders; Rats; Saccharin; Stimulation, Chemical; Time Factors

1976
No synergism between caffeine and saccharin in the induction of sister chromatid exchange in human lymphocytes.
    Hereditas, 1979, Volume: 91, Issue:1

    Topics: Caffeine; Cells, Cultured; Crossing Over, Genetic; Drug Synergism; Humans; Lymphocytes; Saccharin; Sister Chromatid Exchange

1979
High pressure liquid chromatographic determination of sodium saccharin, sodium benzoate, and caffeine in soda beverages: collaborative study.
    Journal - Association of Official Analytical Chemists, 1979, Volume: 62, Issue:5

    Topics: Benzoates; Beverages; Caffeine; Carbonated Beverages; Chromatography, High Pressure Liquid; Saccharin; Sodium

1979
Evidence for withdrawal from caffeine by rats.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 6, Issue:5

    Topics: Animals; Avoidance Learning; Caffeine; Humans; Male; Rats; Saccharin; Substance Withdrawal Syndrome

1977
Coffee drinking and cancer of the lower urinary tract.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:3

    Topics: Aged; Caffeine; Coffee; Cyclamates; Dose-Response Relationship, Drug; Female; Humans; Massachusetts; Middle Aged; Retrospective Studies; Rhode Island; Saccharin; Smoking; Surveys and Questionnaires; Urogenital Neoplasms

1975
Determination of saccharin, sodium benzoate, and caffeine in beverages by reverse phase high-pressure liquid chromatography.
    Journal - Association of Official Analytical Chemists, 1976, Volume: 59, Issue:1

    Topics: Benzoates; Beverages; Caffeine; Chromatography, High Pressure Liquid; Saccharin

1976
Caffeine enhancement of saccharin but not cyclamate flavor avoidance.
    Physiology & behavior, 1987, Volume: 39, Issue:6

    Topics: Animals; Caffeine; Cyclamates; Drug Interactions; Food Preferences; Male; Rats; Rats, Inbred Strains; Saccharin; Taste

1987
Aversive conditioning properties of caffeine in rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Behavior, Animal; Caffeine; Conditioning, Psychological; Cues; Dose-Response Relationship, Drug; Male; Purines; Rats; Rats, Inbred Strains; Reaction Time; Saccharin; Taste

1988
Development of a reconstituted water medium and preliminary validation of the frog embryo teratogenesis assay--Xenopus (FETAX).
    Journal of applied toxicology : JAT, 1987, Volume: 7, Issue:4

    Topics: Animals; Caffeine; Culture Media; Ethanol; Fluorouracil; Saccharin; Teratogens; Water; Xenopus

1987
[Epidemiology of bladder cancers].
    Journal d'urologie, 1985, Volume: 91, Issue:6

    Topics: Aged; Caffeine; Carcinogens; Female; France; Humans; Male; Middle Aged; Neoplasms, Radiation-Induced; Nicotiana; Occupational Diseases; Plants, Toxic; Registries; Risk; Rural Population; Saccharin; Schistosomiasis haematobia; Urban Population; Urinary Bladder Neoplasms

1985
[Dietetics and nutrition in 1972].
    La Revue du praticien, 1972, Feb-21, Volume: 22, Issue:6

    Topics: Adipose Tissue; Alcoholic Intoxication; Anorexia Nervosa; Caffeine; Calcium; Catecholamines; Coffee; Cyclamates; Diabetes Mellitus; Dietary Fats; Dietetics; Drug Interactions; Ethanol; Fasting; Gastrectomy; Humans; Insulin; Lipid Metabolism; Liver; Malabsorption Syndromes; Mushroom Poisoning; Myocardial Infarction; Nutritional Physiological Phenomena; Obesity; Oils; Prognosis; Retina; Saccharin; Substance-Related Disorders; Thiamine; Triglycerides; Vitamin A; Vitamin A Deficiency; Vitamin D

1972
Effects of interaction with surfactants, adsorbents, and other substances on the permeation of chlorpromazine through a dimethyl polysiloxane membrane.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:4

    Topics: Bile Acids and Salts; Caffeine; Charcoal; Chlorpromazine; Diffusion; Drug Interactions; Gelatin; Glycolates; Hydrogen-Ion Concentration; Kinetics; Lactose; Membranes, Artificial; Mucins; Permeability; Riboflavin; Saccharin; Silicones; Surface-Active Agents; Tablets; Talc; Time Factors

1971
Reversed-phase high-performance liquid chromatographic separation of saccharin, caffeine and benzoic acid using non-linear programming.
    Journal of chromatography, 1982, Oct-01, Volume: 247, Issue:2

    Topics: Benzoates; Benzoic Acid; Beverages; Caffeine; Chromatography, High Pressure Liquid; Models, Chemical; Saccharin; Software

1982
Life time occupation, smoking, caffeine, saccharine, hair dyes and bladder carcinogenesis.
    International journal of epidemiology, 1982, Volume: 11, Issue:3

    Topics: Alcohol Drinking; Caffeine; Female; Hair Dyes; Humans; Male; Neoplasms, Multiple Primary; New Jersey; Occupations; Saccharin; Smoking; Urinary Bladder Neoplasms

1982
Amount and dietary sources of caffeine and saccharin intake by individuals ages 5 to 18 years.
    Regulatory toxicology and pharmacology : RTP, 1982, Volume: 2, Issue:4

    Topics: Adolescent; Age Factors; Beverages; Caffeine; Child; Child, Preschool; Diet; Food Analysis; Humans; Saccharin

1982
Effects of caffeine and saccharin on DNA in the bladder epithelium of rats treated with N-butyl-N-(3-carboxy-propyl)-nitrosamine.
    Chemico-biological interactions, 1980, Volume: 29, Issue:3

    Topics: Animals; Caffeine; DNA; Epithelium; Female; Hyperplasia; Nitrosamines; Rats; Saccharin; Urinary Bladder

1980
Effects of sodium saccharin and caffeine on the urinary bladder of rats treated with n-butyl-n-(4-hydroxybutyl)nitrosamine.
    Gan, 1980, Volume: 71, Issue:4

    Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Cocarcinogenesis; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder Neoplasms

1980
Influence of PROP-sensitivity on taste perceptions and hedonics in French women. A study performed without retronasal olfaction.
    Appetite, 1998, Volume: 30, Issue:3

    Topics: Adult; Caffeine; Female; Humans; Perception; Propylthiouracil; Saccharin; Smell; Sodium Chloride; Solutions; Sucrose; Taste Threshold

1998
Caffeine promotes an ethanol-induced conditioned taste aversion: a dose-dependent interaction.
    Experimental and clinical psychopharmacology, 2001, Volume: 9, Issue:3

    Topics: Animals; Avoidance Learning; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Rats; Rats, Wistar; Saccharin; Taste

2001
Stress-induced attenuation of acoustic startle in low-saccharin-consuming rats.
    Biological psychology, 2008, Volume: 79, Issue:2

    Topics: Acoustic Stimulation; Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Drinking Behavior; Electroshock; Male; Rats; Reflex, Startle; Saccharin; Stress, Psychological; Sweetening Agents; Taste; Time Factors

2008
Conditioned flavor avoidance as a measure of withdrawal in rats chronically exposed to a caffeine solution.
    Physiology & behavior, 2008, Sep-03, Volume: 95, Issue:1-2

    Topics: Administration, Oral; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Conditioning, Classical; Drug Administration Schedule; Flavoring Agents; Food Preferences; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Saccharin; Substance Withdrawal Syndrome; Taste; Time Factors

2008
Body weight gain in rats consuming sweetened liquids. Effects of caffeine and diet composition.
    Appetite, 2010, Volume: 55, Issue:3

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Diet, Fat-Restricted; Dietary Fats; Dietary Sucrose; Glucose; Male; Obesity; Rats; Rats, Sprague-Dawley; Saccharin; Weight Gain

2010
[Influences of ion-suppressors on retention behaviors of nine food additives in reversed-phase high performance liquid chromatographic separation].
    Se pu = Chinese journal of chromatography, 2011, Volume: 29, Issue:10

    Topics: Aspartame; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Food Additives; Ions; Saccharin

2011
In-situ synchrotron wide-angle X-ray diffraction as a rapid method for cocrystal/salt screening.
    International journal of pharmaceutics, 2015, Dec-30, Volume: 496, Issue:1

    Topics: Caffeine; Calorimetry, Differential Scanning; Carbamazepine; Crystallization; Hot Temperature; Lamotrigine; Saccharin; Synchrotrons; Triazines; X-Ray Diffraction

2015
Membrane-permeable tastants amplify β2-adrenergic receptor signaling and delay receptor desensitization via intracellular inhibition of GRK2's kinase activity.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Blotting, Western; Caffeine; Cell Membrane Permeability; Cyclic AMP; Enzyme Inhibitors; Flavanones; G-Protein-Coupled Receptor Kinase 2; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Intracellular Space; Isoproterenol; Isoquinolines; Phosphorylation; Receptors, Adrenergic, beta-2; RNA Interference; Saccharin; Signal Transduction; Sulfonamides; Taste; Tryptophan

2015
Independent comparison study of six different electronic tongues applied for pharmaceutical analysis.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Biosensing Techniques; Caffeine; Chemistry, Pharmaceutical; Citrates; Citric Acid; Electrical Equipment and Supplies; Equipment Design; Lactose; Models, Theoretical; Polysaccharides; Potentiometry; Principal Component Analysis; Reproducibility of Results; Saccharin; Technology, Pharmaceutical

2015
Removal and attenuation of sewage effluent combined tracer signals of phosphorus, caffeine and saccharin in soil.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 223

    Topics: Adsorption; Caffeine; Environmental Monitoring; Phosphorus; Saccharin; Sewage; Soil; Soil Pollutants; Sweetening Agents; United Kingdom; Water Pollutants, Chemical

2017
Taste Perception and Caffeine Consumption: An fMRI Study.
    Nutrients, 2018, Dec-24, Volume: 11, Issue:1

    Topics: Caffeine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Saccharin; Sucrose; Taste Perception

2018
Intravenous and oral caffeine self-administration in rats.
    Drug and alcohol dependence, 2019, 10-01, Volume: 203

    Topics: Administration, Intravenous; Administration, Oral; Animals; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Motivation; Rats; Reinforcement, Psychology; Reward; Saccharin; Self Administration

2019
Caffeine-based flavor preference conditioning in the rat.
    Learning & behavior, 2022, Volume: 50, Issue:2

    Topics: Animals; Caffeine; Conditioning, Classical; Food Preferences; Humans; Rats; Saccharin; Taste; Water

2022
Suspect screening of pharmaceuticals, illicit drugs, pesticides, and other emerging contaminants in Argentinean Piaractus mesopotamicus, a fish species used for local consumption and export.
    Chemosphere, 2022, Volume: 309, Issue:Pt 1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anti-Bacterial Agents; Argentina; Caffeine; Cyclamates; Diethylhexyl Phthalate; Environmental Monitoring; Illicit Drugs; Lisinopril; Pesticides; Plasticizers; Saccharin; Salicylic Acid; Sewage; Sweetening Agents; Water Pollutants, Chemical

2022
Adsorption of aqueous phase contaminants of emerging concern by activated carbon: Comparative fixed-bed column study and in situ regeneration methods.
    Journal of hazardous materials, 2023, 10-05, Volume: 459

    Topics: Adsorption; Caffeine; Charcoal; Saccharin; Sulfamethoxazole; Water; Water Pollutants, Chemical; Water Purification

2023
Synergistic Effect of Saccharin and Caffeine on Antiproliferative Activity in Human Ovarian Carcinoma Ovcar-3 Cells.
    International journal of molecular sciences, 2023, Sep-22, Volume: 24, Issue:19

    Topics: Apoptosis; Caffeine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Female; Humans; Ovarian Neoplasms; Saccharin

2023