saccharin has been researched along with aspartame in 148 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (19.59) | 18.7374 |
| 1990's | 27 (18.24) | 18.2507 |
| 2000's | 28 (18.92) | 29.6817 |
| 2010's | 45 (30.41) | 24.3611 |
| 2020's | 19 (12.84) | 2.80 |
| Authors | Studies |
|---|---|
| DuBois, GE; Stephenson, RA | 1 |
| Olson, BL | 1 |
| Morrison, AB | 1 |
| Kuribara, H; Ogawa, H; Okuizumi, K; Tadokoro, S | 1 |
| Bär, A; Biermann, C | 1 |
| Borges Yáñez, SA | 1 |
| Rolls, BJ | 1 |
| Canty, DJ; Chan, MM | 1 |
| Chen, LN; Parham, ES | 1 |
| Grenby, TH; Saldanha, MG | 1 |
| Balog, JM; Millar, RI | 1 |
| Horwitz, DL; Kobe, P; McLane, M | 1 |
| Nabors, LO | 1 |
| Blundell, JE; Carlyle, JA; Hill, AJ; Rogers, PJ | 1 |
| London, RS | 1 |
| Kaufman, LN; Landsberg, L; Walgren, MC; Young, JB | 1 |
| Alfin-Slater, RB; Pi-Sunyer, FX | 1 |
| Berg, CJ; Cummings, EM; Flament, M; Ismond, DR; Kruesi, MJ; Rapoport, JL; Yarrow, M; Zahn-Waxler, C | 1 |
| Abrams, M; Sclafani, A | 1 |
| Baines, CJ | 1 |
| Edgar, WM; Rugg-Gunn, AJ | 1 |
| Beeker, TG; Crofton, VA; Schiffman, SS | 1 |
| Cody, MM; Kunkel, ME | 1 |
| Ehrcke, LA; Sprowl, DJ | 1 |
| Fukushima, S; Hagiwara, A; Ito, N; Kitaori, M; Shibata, M | 1 |
| Eberle, G | 1 |
| Slee, AM; Tanzer, JM | 1 |
| Adams, BA | 1 |
| Lederer, J | 1 |
| Linke, HA | 1 |
| Shaw, JH | 1 |
| Lindner, K | 1 |
| Hoppe, K | 1 |
| Malyshev, SD | 1 |
| Butchko, HH; Park, KK; Sanders, PG; Schemehorn, BR; Stookey, GK | 1 |
| Devine, J; Engelman, K; Teff, KL | 1 |
| Besford, J; Easterby-Smith, V; Heath, MR | 1 |
| van Dusseldorp, M | 1 |
| Renwick, AG | 2 |
| Kinsbourne, M | 1 |
| Imfeld, T | 1 |
| Danilova, V; DuBois, GE; Hellekant, G; Ninomiya, Y; Roberts, TW | 1 |
| Ahern, MJ; Cmielewski, PL; Hall, PM; Ilsley, AH; Plummer, JL | 1 |
| Abdollahi, M; Etemad, F; Nikfar, S; Sharifzadeh, M | 1 |
| McMillen, BA; Williams, HL | 1 |
| Abdollahi, M; Etemad, F; Nikfar, S; Sarkarati, F | 1 |
| De Francisco, JC; Dess, NK | 1 |
| Jijakli, H; Louchami, K; Malaisse, WJ; Malaisse-Lagae, F; Vanonderbergen, A | 1 |
| Berardi, D; Lambe, J; Leclercq, C; Sorbillo, MR | 1 |
| Birch, GG; Parke, SA | 1 |
| Cardello, HM; Da Silva, MA; Damasio, MH | 1 |
| Yebra-Biurrun, MC | 1 |
| Cohen, S | 1 |
| Garnier-Sagne, I; Leblanc, JC; Verger, P | 1 |
| Bachmanov, AA; Beauchamp, GK; Inoue, M; McCaughey, SA | 1 |
| Bohlen, H; Diehl, V; Weihrauch, MR | 1 |
| Zhang, XY | 1 |
| Alzin, M; Busk, L; Enghardt-Barbieri, H; Ilbäck, NG; Jahrl, S | 1 |
| Brust, P; Ozeck, M; Servant, G; Xu, H | 1 |
| Diehl, V; Weihrauch, MR | 1 |
| Akiyama, K; Koyama, M; Sasaki, T; Uchibori, N; Wada, I; Yoshida, K | 1 |
| Guo, Y; James, FS; Ye, M; Zhu, Y | 1 |
| Cho, YH; Cho, YJ; Choi, SH; Chung, MS; Kim, CJ; Suh, HJ; Yoo, W | 1 |
| Arana Nicolás, E; Capitán-Vallvey, LF; García-Jiménez, JF; Valencia, MC | 1 |
| Dasgupta, J; Doshani, A; Elliott, RA; Tincello, DG | 1 |
| Adams, B; Bennett, R; French, A; Neggers, Y; Vincent, JB | 1 |
| Fabricius, N; Fagt, S; Leth, T | 1 |
| Cavicchioli, M; Leite, CQ; Massabni, AC; Sato, DN | 1 |
| Anduni, GJ; Farías, ME; Manca de Nadra, MC | 1 |
| Andersen, R; Fagt, S; Jensen, U; Leth, T | 1 |
| Andreatta, MM; Eynard, AR; Lantieri, MJ; Muñoz, SE; Navarro, A | 1 |
| Boullata, J; McCauley, LA; Whitehouse, CR | 1 |
| Camiña, JM; Cantarelli, MA; Marchevsky, EJ; Pellerano, RG | 1 |
| Bandyopadhyay, A; Ghoshal, S; Mukherjee, A | 1 |
| Bursey, RG | 1 |
| Barceloux, DG; Rangan, C | 1 |
| Case, RM; Gupta, N; Little, TJ; McLaughlin, JT; Thompson, DG | 1 |
| Cragin, T; Danilova, V; Elmer, D; Hellekant, G; Roberts, T | 1 |
| Ackroff, K; Bahrani, M; Sclafani, A; Zukerman, S | 1 |
| Bonyár-Müller, K; Ember, I; Gombos, K; Gubicskó-Kisbenedek, A; Hajnal, B; Marton, K; Polyák, E; Szabó, S | 1 |
| Cho, KH; Kim, JY; Seo, J | 1 |
| Chen, X; Jin, M; Li, X; Yao, S; Zhao, Y | 1 |
| Geraedts, MC; Saris, WH; Troost, FJ | 1 |
| Farkas, A; Híd, J | 1 |
| Abe, K; Ishiguro, M; Koizumi, A; Masuda, K; Misaka, T; Nakajima, K; Tanaka, T | 1 |
| Cui, M; Ha, M; Khaleduzzaman, M; Li, X; Liu, B; Meng, XY; Zhang, Z | 1 |
| Ballard, CR; Batista, BAM; Bertoluci, MC; Feijó, FM; Foletto, KC; Neves, AM; Ribeiro, MFM | 1 |
| Nagaraj, T; Patel, VB; Patil, RB; Prashant, GM | 1 |
| Bae, DH; Choi, SH; Ha, MS; Ha, SD | 1 |
| Diogo, JS; Lino, CM; Pena, A; Silva, LS | 1 |
| Pool, EJ; Rahiman, F | 1 |
| Bachleda, P; Dvorak, Z; Kamenickova, A; Pecova, M | 1 |
| Astbury, N; Bryant, CE; McLaughlin, JT; Nandra, G; Wasse, LK | 1 |
| Fujiwara, T; Hayafuji, C; Kobayashi, C; Tahara, S; Uematsu, Y; Yasui, A | 1 |
| Cho, KH; Choi, I; Kim, J; Kim, JY; Park, KH | 1 |
| Elinav, E; Gilad, S; Halpern, Z; Harmelin, A; Israeli, D; Kolodkin-Gal, I; Korem, T; Kuperman, Y; Maza, O; Segal, E; Shapiro, H; Suez, J; Thaiss, CA; Weinberger, A; Zeevi, D; Zilberman-Schapira, G; Zmora, N | 1 |
| van Eyk, AD | 1 |
| Kannan, K; Subedi, B | 1 |
| Khan, SA | 1 |
| de Oliveira, MA; Dolzan, MD; Micke, GA; Vistuba, JP; Vitali, L | 1 |
| Ahmed, MM; Alkafafy, Mel-S; El-Shazly, SA; Ibrahim, ZS | 1 |
| Bauman, V; Blau, JE; Gardner, AL; Garraffo, HM; Rother, KI; Sylvetsky, AC; Walter, PJ | 1 |
| Goscinny, S; Janvier, S; Le Donne, C; Van Loco, J | 1 |
| Brown, RE; Kuk, JL | 1 |
| Gan, Z; Gao, C; Li, X; Li, Y; Ma, L; Sun, H; Zhang, T | 1 |
| Carakostas, MC; Magnuson, BA; Moore, NH; Poulos, SP; Renwick, AG | 1 |
| Chokumnoyporn, N; Chonpracha, P; Jirangrat, W; Prinyawiwatkul, W; Sriwattana, S; Wardy, W | 1 |
| Do, B; Kwon, H; Lee, G; Lee, Y; Lim, HS; Yun, SS | 1 |
| Chen, S; Li, Z; Xu, Y; Zhang, X | 1 |
| Cavella, S; Dell'Amura, F; Di Monaco, R; Miele, NA; Picone, D; Rega, MF | 1 |
| Chan, CB; Hashemi, Z; Subhan, FB | 1 |
| Miyakawa, H; Monma, K; Tahara, S; Uematsu, Y; Yamajima, Y; Yamamoto, S | 1 |
| Hong, JH; Hwang, M; Kim, M; Kwon, H; Lee, G; Lim, HS; Yun, SS | 1 |
| Alves, VR; de Oliveira, MAL; Dolzan, MD; Dos Santos, HF; Duarte, LM; Izumi, CMS; Micke, GA; Paschoal, D | 1 |
| Angarita Dávila, L; de Assis Costa, J; Durán Agüero, S; Escobar Contreras, MC; Rojas Gómez, D | 1 |
| Erbaş, O; Erdoğan, MA; Eroglu, HA; Gürkan, FT; Khalilnezhad, A; Solmaz, V; Taskiran, D; Yiğittürk, G | 1 |
| Kumar Choudhary, A; Pretorius, E | 1 |
| Pyrogianni, V | 1 |
| Higgins, KA; Mattes, RD | 1 |
| Durán Agüero, S; Espinoza Espinoza, J; Fuentealba Arévalo, F; Salazar Ibacahe, C | 1 |
| Aderemi-Williams, R; Ogbuefi, I; Soremekun, R | 1 |
| Chukwuma, CI; Dlamini, SN; Ibrahim, MA; Islam, MS; Mchunu, N; Oyebode, OA | 1 |
| Li, B; Ren, HB; Wang, YT; Xu, XJ; Yin, JY; Zhang, YH; Zhu, H | 1 |
| Abadia-Molina, F; Pastor-Villaescusa, B; Plaza-Diaz, J; Rueda-Robles, A; Ruiz-Ojeda, FJ | 1 |
| Ayyadurai, N; Ilamaran, M; Shanmugam, G; Thankachan, SN | 1 |
| Basílio, M; Lino, CM; Pena, A; Pereira, AMPT; Silva, LJG | 1 |
| Chichger, H; Shil, A | 1 |
| Chichger, H; Enuwosa, E; Gautam, L; King, L | 1 |
| Ahmad, MZ; Castro-Muñoz, R; Chávez-Muñoz, M; Córdova-Almeida, R; Correa-Delgado, M; Gontarek-Castro, E; Hernández-Torres, CE; Lara-Nava, D; Velásquez-Chávez, VF | 1 |
| Bar, T; Golberg, K; Halpern, B; Kramarsky-Winter, E; Kushmaro, A; Marks, RS; Markus, V; Özer, N; Shagan, M; Share, O; Teralı, K | 1 |
| Guo, J; Yu, Z | 1 |
| Durán-Domínguez-de-Bazúa, MD; García-Gómez, RS; Mendoza-Pérez, S | 1 |
| Ben-Zeev Brik, R; Bukimer, A; Cohen, Y; Dori-Bachash, M; Elinav, E; Eliyahu-Miller, S; Federici, S; Fischbein, R; Harmelin, A; Heinemann, M; Itkin, M; Leshem, A; Linevsky, R; Malitsky, S; Metz, A; Mor, U; Segal, E; Shapiro, H; Sharov, O; Stein-Thoeringer, CK; Stettner, N; Suez, J; Valdés-Mas, R; Zmora, N; Zur, M | 1 |
| Andrade, TFS; Arisseto-Bragotto, AP; Nicoluci, ÍG; Takehara, CT | 1 |
| Iizuka, K | 1 |
| Drewnowski, A; Fulgoni, VL | 1 |
| Brenes, JC; Cavagnari, BM; Gómez, G; Kovalskys, I; Quesada, D | 1 |
| Alicandro, G; La Vecchia, C; Moretto, A; Pavanello, S | 1 |
| Abrigo, K; Cáceres, P; Carvajal, B; Gotteland, M; López-Arana, S; Peralta, R; Prado, G; Sambra, V | 1 |
| Bujagić, IM; Grujić, S; Gvozdić, E; Đurkić, T | 1 |
| Carr, JJ; Jacobs, DR; Lees, SJ; Lewis, CE; Shikany, JM; Steffen, BT; Steffen, LM; Terry, JG; Yi, SY; Zhou, X | 1 |
21 review(s) available for saccharin and aspartame
| Article | Year |
|---|---|
[Sugar substitutes in the prevention of dental caries: review of the literature].
Topics: Aspartame; Dental Caries; Diet, Cariogenic; Humans; Saccharin; Sorbitol; Sweetening Agents; Xylitol | 1991 |
Effects of intense sweeteners on hunger, food intake, and body weight: a review.
Topics: Aspartame; Body Weight; Eating; Humans; Hunger; Saccharin; Sweetening Agents; Thiazines | 1991 |
[Sweetening agents: saccharin--cyclamate and its metabolites--aspartame].
Topics: Abnormalities, Drug-Induced; Animals; Aspartame; Chromosome Aberrations; Cricetinae; Cyclamates; Cyclohexanols; Cyclohexanones; Cyclohexylamines; Haplorhini; Mutation; Neoplasms; Rats; Saccharin; Sweetening Agents | 1980 |
Sweeteners--an overview. Part. 1.
Topics: Aspartame; Chalcone; Chalcones; Cyclamates; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hesperidin; Jaw, Edentulous, Partially; Legislation, Drug; Oxazines; Saccharin; Sugar Alcohols; Thiazines; Xylitol | 1981 |
Intense sweeteners, food intake, and the weight of a body of evidence.
Topics: Appetite; Aspartame; Beverages; Blood Glucose; Body Weight; Eating; Energy Intake; Humans; Hunger; Insulin; Saccharin; Sweetening Agents | 1994 |
Efficacy of sweeteners and sugar substitutes in caries prevention.
Topics: Aspartame; Cariostatic Agents; Cyclamates; Dental Caries; Disaccharides; Humans; Maltose; Mannitol; Saccharin; Sorbitol; Sugar Alcohols; Sweetening Agents; Xylitol | 1993 |
"Inactive" ingredients in pharmaceutical products: update (subject review). American Academy of Pediatrics Committee on Drugs.
Topics: Adolescent; Anti-Asthmatic Agents; Aspartame; Benzalkonium Compounds; Benzyl Alcohol; Benzyl Alcohols; Child; Child, Preschool; Coloring Agents; Drug Labeling; Excipients; Food Additives; Humans; Lactose; Nebulizers and Vaporizers; Pharmaceutical Vehicles; Propylene Glycol; Propylene Glycols; Saccharin; Sulfites | 1997 |
Flow injection determinations of artificial sweeteners: a review.
Topics: Aspartame; Biosensing Techniques; Cyclamates; Flow Injection Analysis; Food Additives; Potentiometry; Saccharin; Spectrophotometry; Spectrophotometry, Atomic; Sweetening Agents | 2000 |
[Artificial sweeteners--are they potentially carcinogenic?].
Topics: Animals; Aspartame; Carbonated Beverages; Carcinogenicity Tests; Carcinogens; Clinical Trials as Topic; Cyclamates; Epidemiologic Studies; Humans; Rats; Risk; Saccharin; Sweetening Agents | 2001 |
Artificial sweeteners--do they bear a carcinogenic risk?
Topics: Aspartame; Case-Control Studies; Cyclamates; Epidemiologic Studies; Humans; Neoplasms; Risk Factors; Saccharin; Sweetening Agents | 2004 |
The intake of intense sweeteners - an update review.
Topics: Adult; Aspartame; Cyclamates; Dipeptides; Europe; Female; Humans; Male; Saccharin; Sucrose; Sweetening Agents; Thiazines | 2006 |
The potential toxicity of artificial sweeteners.
Topics: Animals; Aspartame; Dipeptides; Energy Intake; Female; Health Education; Humans; Occupational Health Nursing; Public Health; Risk Factors; Saccharin; Safety; Sweetening Agents; Thiazines | 2008 |
Food additives and sensitivities.
Topics: Anti-Bacterial Agents; Antioxidants; Aspartame; Bronchiolitis Obliterans; Coloring Agents; Cyclamates; Diacetyl; Emulsifying Agents; Food Additives; Food Handling; Food Hypersensitivity; Food Microbiology; Food Preservatives; History, 20th Century; Humans; Methemoglobinemia; Nitrates; Nitrites; Phenylketonurias; Saccharin; Sodium Glutamate; Sulfites | 2009 |
Artificial sweeteners: safe or unsafe?
Topics: Aspartame; Diabetes Mellitus, Type 2; Dipeptides; Humans; Neoplasms; Obesity; Saccharin; Sucrose; Sweetening Agents; Thiazines; Weight Gain | 2015 |
Biological fate of low-calorie sweeteners.
Topics: Animals; Aspartame; Diabetes Mellitus; Diterpenes, Kaurane; Energy Intake; Glucosides; Humans; Legislation, Drug; Microbiota; Saccharin; Sucrose; Sweetening Agents; Thiazines | 2016 |
The impact of low and no-caloric sweeteners on glucose absorption, incretin secretion, and glucose tolerance.
Topics: Animals; Aspartame; Blood Glucose; Carbohydrate Metabolism; Gastrointestinal Tract; Glucose Intolerance; Humans; Incretins; Insulin; Insulin Secretion; Meta-Analysis as Topic; Models, Animal; Non-Nutritive Sweeteners; Randomized Controlled Trials as Topic; Saccharin; Sucrose; Thiazines | 2017 |
Noncaloric Sweeteners in Children: A Controversial Theme.
Topics: Aspartame; Child; Cyclamates; Energy Intake; Food Additives; Humans; Obesity; Risk Assessment; Saccharin; Stevia; Sucrose; Sweetening Agents; Thiazines | 2018 |
Plausible Biological Interactions of Low- and Non-Calorie Sweeteners with the Intestinal Microbiota: An Update of Recent Studies.
Topics: Aspartame; Diterpenes, Kaurane; Gastrointestinal Microbiome; Glucosides; Humans; Non-Nutritive Sweeteners; Polymers; Saccharin; Sucrose; Thiazines | 2020 |
Natural sweeteners: Sources, extraction and current uses in foods and food industries.
Topics: Aspartame; Food Industry; Saccharin; Sweetening Agents | 2022 |
Is the Use of Artificial Sweeteners Beneficial for Patients with Diabetes Mellitus? The Advantages and Disadvantages of Artificial Sweeteners.
Topics: Animals; Aspartame; Cohort Studies; Diabetes Mellitus; Humans; Obesity; Saccharin; Sweetening Agents | 2022 |
Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence.
Topics: Aspartame; Humans; Neoplasms; Saccharin; Sugars; Sweetening Agents | 2023 |
7 trial(s) available for saccharin and aspartame
| Article | Year |
|---|---|
Response to single dose of aspartame or saccharin by NIDDM patients.
Topics: Adult; Aspartame; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Female; Glucagon; Humans; Insulin; Kinetics; Male; Middle Aged; Reference Values; Saccharin | 1988 |
Effects of sugar and aspartame on aggression and activity in children.
Topics: Aggression; Aspartame; Child Behavior; Child Behavior Disorders; Child, Preschool; Dietary Carbohydrates; Dipeptides; Glucose; Humans; Male; Motor Activity; Saccharin; Sucrose | 1987 |
[The psychophysics of sweet taste. 7. New determination of sweet taste parameters of acesulfame, aspartame, cyclamate, saccharin, glucose and sorbitol].
Topics: Adult; Aspartame; Cyclamates; Female; Glucose; Humans; Middle Aged; Psychophysics; Saccharin; Sorbitol; Sweetening Agents; Taste; Thiazines | 1995 |
Sweet taste: effect on cephalic phase insulin release in men.
Topics: Adolescent; Adult; Aspartame; Blood Glucose; Humans; Insulin; Male; Saccharin; Sucrose; Sweetening Agents; Taste | 1995 |
Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans.
Topics: Acetates; Adult; Appetite Regulation; Aspartame; Breath Tests; Carbon Isotopes; Dose-Response Relationship, Drug; Eating; Female; Flavanones; Fructose; Gastric Emptying; Glucose; Humans; Hunger; Intubation, Gastrointestinal; Male; Middle Aged; Perception; Quinine; Saccharin; Satiation; Single-Blind Method; Sweetening Agents; Taste; Time Factors; Young Adult | 2009 |
A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity.
Topics: Adult; Aspartame; Beverages; Body Mass Index; Body Weight; Diet; Dietary Sucrose; Diterpenes, Kaurane; Energy Intake; Feeding Behavior; Female; Humans; Male; Non-Nutritive Sweeteners; Obesity; Overweight; Saccharin; Stevia; Sucrose; Sweetening Agents; Weight Gain; Young Adult | 2019 |
Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance.
Topics: Adult; Animals; Aspartame; Blood Glucose; Humans; Mice; Microbiota; Non-Nutritive Sweeteners; Saccharin | 2022 |
120 other study(ies) available for saccharin and aspartame
| Article | Year |
|---|---|
Diterpenoid sweeteners. Synthesis and sensory evaluation of stevioside analogues with improved organoleptic properties.
Topics: Diterpenes; Diterpenes, Kaurane; Glucosides; Glycosides; Humans; Sweetening Agents; Taste; Terpenes | 1985 |
An in vitro study of the effects of artificial sweeteners on adherent plaque formation.
Topics: Aspartame; Cyclamates; Dental Plaque; Saccharin; Streptococcus mutans; Sucrose; Sweetening Agents | 1977 |
Sugar substitutes.
Topics: Animals; Aspartame; Cricetinae; Cyclamates; Humans; Male; Mice; Neoplasms, Experimental; Rats; Saccharin; Sweetening Agents; Urinary Bladder Neoplasms | 1979 |
[Effects of sweetners on licking behavior in schedule-induced polydipsia].
Topics: Animals; Aspartame; Conditioning, Operant; Cyclamates; Dose-Response Relationship, Drug; Drinking Behavior; Male; Rats; Reinforcement Schedule; Saccharin; Sodium Chloride; Sucrose; Sweetening Agents | 1977 |
Synthetic sweetners: cyclamates, saccharin, aspartame.
Topics: Animals; Aspartame; Aspartic Acid; Beverages; Cyclamates; Cyclohexylamines; Diet, Reducing; Dipeptides; Female; Fetus; Food; Humans; Maternal-Fetal Exchange; Mice; Phenylketonurias; Piperazines; Placenta; Polyps; Pregnancy; Primates; Rats; Saccharin; United States; United States Food and Drug Administration; Urinary Bladder Neoplasms; Uterine Neoplasms | 1975 |
Intake of intense sweeteners in Germany.
Topics: Adolescent; Adult; Aspartame; Beverages; Child; Child, Preschool; Cholesterol, Dietary; Cyclamates; Diabetes Mellitus; Diet Records; Diet, Reducing; Female; Follow-Up Studies; Germany; Humans; Male; Middle Aged; Saccharin; Surveys and Questionnaires; Sweetening Agents | 1992 |
Sweetener intakes.
Topics: Adolescent; Adult; Aged; Aspartame; Beverages; Child; Child, Preschool; Diabetes Mellitus; Humans; Middle Aged; Saccharin; Sweetening Agents; United Kingdom; Yogurt | 1991 |
Effects of consumption of caloric vs noncaloric sweet drinks on indices of hunger and food consumption in normal adults.
Topics: Adult; Analysis of Variance; Aspartame; Beverages; Eating; Female; Humans; Hunger; Male; Saccharin; Sucrose; Sweetening Agents; Water | 1991 |
College students' use of high-intensity sweeteners is not consistently associated with sugar consumption.
Topics: Adult; Aspartame; Diet Records; Diet, Reducing; Female; Humans; Male; Saccharin; Sex Characteristics; Students; Sucrose; Surveys and Questionnaires; Sweetening Agents | 1991 |
Studies of the inhibitory action of intense sweeteners on oral microorganisms relating to dental health.
Topics: Aspartame; Bacteria; Cyclamates; Dental Plaque; Humans; Hydrogen-Ion Concentration; Muscle Proteins; Saccharin; Streptococcus mutans; Sweetening Agents; Talin; Thiazines | 1986 |
Influence of the sense of taste on broiler chick feed consumption.
Topics: Animal Feed; Animals; Aspartame; Chickens; Citrates; Citric Acid; Eating; Male; Quinine; Saccharin; Sodium Chloride; Taste; Weight Gain | 1989 |
Position of the American Dietetic Association: appropriate use of nutritive and non-nutritive sweeteners.
Topics: Aspartame; Cyclamates; Dietetics; Fructose; Humans; Mannitol; Saccharin; Societies; Sorbitol; Sucrose; Sweetening Agents | 1987 |
Saccharin and aspartame: are they safe to consume during pregnancy?
Topics: Adult; Animals; Aspartame; Dipeptides; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Saccharin; Urinary Bladder Neoplasms | 1988 |
Uncoupling sweet taste and calories: comparison of the effects of glucose and three intense sweeteners on hunger and food intake.
Topics: Adult; Appetite; Aspartame; Energy Intake; Female; Food Preferences; Glucose; Glucose Solution, Hypertonic; Humans; Hunger; Male; Saccharin; Satiety Response; Sweetening Agents; Thiazines | 1988 |
Saccharin and aspartame. Are they safe to consume during pregnancy?
Topics: Aspartame; Aspartic Acid; Dipeptides; Female; Humans; Methanol; Phenylalanine; Pregnancy; Saccharin | 1988 |
The effects of various carbohydrates on sympathetic activity in heart and interscapular brown adipose tissue of the rat.
Topics: Acarbose; Adipose Tissue, Brown; Animals; Aspartame; Carbohydrates; Cholestyramine Resin; Fructose; Heart; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Saccharin; Sucrose; Sympathetic Nervous System; Trisaccharides | 1987 |
Sugar and sugar substitutes. Comparisons and indications.
Topics: Animals; Aspartame; Diet, Diabetic; Diet, Reducing; Dietary Carbohydrates; Energy Intake; Humans; Rats; Saccharin; Sweetening Agents; United States; United States Food and Drug Administration; Urinary Bladder Neoplasms | 1987 |
Rats show only a weak preference for the artificial sweetener aspartame.
Topics: Animals; Aspartame; Choice Behavior; Dipeptides; Dose-Response Relationship, Drug; Drinking; Female; Rats; Rats, Inbred Strains; Saccharin; Sucrose; Taste | 1986 |
Table top artificial sweeteners. Current use in Canada.
Topics: Aspartame; Canada; Cyclamates; Diet; Humans; Saccharin; Sweetening Agents | 1985 |
Sweeteners and dental health.
Topics: Animals; Aspartame; Carbohydrates; Cariostatic Agents; Disaccharides; Humans; Legislation, Drug; Mannitol; Saccharin; Sorbitol; Sugar Alcohols; Sweetening Agents; United Kingdom; Xylitol | 1985 |
Sensory evaluation of soft drinks with various sweeteners.
Topics: Adolescent; Adult; Aspartame; Beverages; Carbonated Beverages; Cyclamates; Discrimination, Psychological; Female; Humans; Male; Saccharin; Sucrose; Sweetening Agents; Taste; Thiazines | 1985 |
Acceptability of aspartame- and saccharin-sweetened fruits to users and nonusers of artificial sweeteners.
Topics: Aspartame; Dipeptides; Fruit; Humans; Saccharin; Taste | 1985 |
Sweeteners: consumer acceptance in tea.
Topics: Aspartame; Consumer Behavior; Costs and Cost Analysis; Dipeptides; Food Preferences; Fructose; Humans; Saccharin; Sucrose; Taste; Tea | 1984 |
Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Aspartame; Butylhydroxybutylnitrosamine; Diterpenes; Diterpenes, Kaurane; Glucosides; Hyperplasia; Male; Rats; Rats, Inbred F344; Saccharin; Sweetening Agents; Terpenes; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
[Prophylaxis of dental caries using sugar substitutes].
Topics: Adult; Aspartame; Cariogenic Agents; Child, Preschool; Cyclamates; Dental Care; Dental Caries; Fluoridation; Germany, West; Humans; Nutritive Value; Oral Hygiene; Saccharin; Sugar Alcohols; Sweetening Agents | 1984 |
Saccharin inhibits tooth decay in laboratory models.
Topics: Animals; Aspartame; Dental Caries; Diet, Cariogenic; Germ-Free Life; Rats; Rats, Inbred Strains; Saccharin; Streptococcus mutans | 1983 |
How sweet it is.
Topics: Aspartame; Food Additives; Saccharin; Sweetening Agents | 1983 |
Adherence of Streptococcus mutans to smooth surfaces in the presence of artificial sweeteners.
Topics: Adhesiveness; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Saccharin; Streptococcus mutans; Sweetening Agents; Thiazines | 1983 |
Non-nutritive sweetening agents.
Topics: Aspartame; Cyclamates; Glycoproteins; Humans; Plant Proteins; Saccharin; Sweetening Agents; Tryptophan | 1980 |
[Sweetener Sweetly--dietetic sweetness].
Topics: Aspartame; Diet; Diet, Diabetic; Humans; Saccharin; Sweetening Agents | 1995 |
Acidogenicity of high-intensity sweeteners and polyols.
Topics: Adult; Analysis of Variance; Aspartame; Dental Plaque; Diet, Cariogenic; Fructose; Humans; Hydrogen-Ion Concentration; Middle Aged; Saccharin; Sorbitol; Sucrose; Sweetening Agents; Thiazines; Xylitol | 1995 |
The effect of age on the recognition thresholds of three sweeteners: sucrose, saccharin and aspartame.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Aspartame; Female; Humans; Male; Middle Aged; Pilot Projects; Saccharin; Statistics, Nonparametric; Sucrose; Surveys and Questionnaires; Sweetening Agents; Taste Threshold | 1994 |
[Consumption of sugar substitutes by (obese) children: not hazardous to their health].
Topics: Adolescent; Aspartame; Child; Child, Preschool; Energy Metabolism; Humans; Obesity; Saccharin; Sugar Alcohols; Sweetening Agents | 1994 |
Sugar and the hyperactive child.
Topics: Aspartame; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior; Cognition; Dietary Carbohydrates; Female; Humans; Male; Saccharin; Sucrose | 1994 |
Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners.
Topics: Adult; Animals; Aspartame; Child; Cyclamates; Dietetics; Dipeptides; Female; Fructose; Humans; Pregnancy; Saccharin; Societies; Sucrose; Sugar Alcohols; Sweetening Agents; Thiazines | 1993 |
Taste in chimpanzee: I. The summated response to sweeteners and the effect of gymnemic acid.
Topics: Animals; Aspartame; Chorda Tympani Nerve; Electrophysiology; Female; Male; Pan troglodytes; Saccharin; Saponins; Sweetening Agents; Taste; Triterpenes | 1996 |
Use of artificial sweeteners to promote alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Aspartame; Cyclamates; Drinking Behavior; Liver Cirrhosis, Alcoholic; Male; Rats; Rats, Inbred Strains; Saccharin; Sweetening Agents | 1997 |
Effects of sweetening agents on morphine-induced analgesia in mice by formalin test.
Topics: Animals; Aspartame; Male; Mice; Morphine; Pain Measurement; Pain Threshold; Saccharin; Sucrose; Sweetening Agents | 1997 |
Role of taste and calories in the selection of ethanol by C57BL/6NHsd and Hsd:ICR mice.
Topics: Alcohol Drinking; Animals; Aspartame; Behavior, Animal; Cacao; Energy Intake; Ethanol; Food Preferences; Glucose; Lithium Chloride; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Quinine; Saccharin; Solutions; Taste | 1998 |
Interaction between calcium channel blockers and sweetening agents on morphine-induced analgesia in mice by formalin test.
Topics: Analgesics; Animals; Aspartame; Calcium Channel Blockers; Diltiazem; Drug Interactions; Male; Mice; Morphine; Nifedipine; Pain Measurement; Saccharin; Sucrose; Sweetening Agents; Verapamil | 1998 |
Aspartame consumption in rats selectively bred for high versus low saccharin intake.
Topics: Animals; Aspartame; Female; Male; Rats; Saccharin; Sweetening Agents; Taste | 1998 |
Effects of artificial sweeteners on insulin release and cationic fluxes in rat pancreatic islets.
Topics: Animals; Aspartame; Calcium; Cations; Cyclamates; Diterpenes; Diterpenes, Kaurane; Female; Glucose; Glucosides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Potassium; Rats; Rats, Wistar; Rubidium; Saccharin; Sweetening Agents; Terpenes; Thiazines | 1998 |
Intake of saccharin, aspartame, acesulfame K and cyclamate in Italian teenagers: present levels and projections.
Topics: Adolescent; Adult; Aspartame; Cyclamates; Diet Surveys; Humans; Italy; Maximum Allowable Concentration; Saccharin; Sex Factors; Sweetening Agents; Thiazines | 1999 |
Solution properties and sweetness response of selected bulk and intense sweeteners.
Topics: Aspartame; Cyclamates; Maltose; Saccharin; Sucrose; Sugar Alcohols; Sweetening Agents; Taste; Thiazines | 1999 |
Measurement of the relative sweetness of stevia extract, aspartame and cyclamate/saccharin blend as compared to sucrose at different concentrations.
Topics: Aspartame; Cyclamates; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Glucosides; Humans; Hydrogen-Ion Concentration; Saccharin; Sucrose; Sweetening Agents; Taste Threshold; Terpenes | 1999 |
What's the truth about the health risks of sugar substitutes such as saccharin and aspartame?
Topics: Animals; Aspartame; Headache; Humans; Rats; Saccharin; Urinary Bladder Neoplasms | 2001 |
Calculation of the intake of three intense sweeteners in young insulin-dependent diabetics.
Topics: Adolescent; Aspartame; Body Weight; Child; Diabetes Mellitus, Type 1; Energy Intake; Female; Food Additives; France; Health Surveys; Humans; Male; Saccharin; Surveys and Questionnaires; Sweetening Agents; Thiazines | 2001 |
Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice.
Topics: Animals; Aspartame; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Electrophysiology; Glucans; Guanidines; Male; Mice; Mice, Inbred C57BL; Oligosaccharides; Plant Proteins; Quinine; Saccharin; Species Specificity; Sucrose; Sweetening Agents; Taste; Taste Threshold; Thiazines | 2001 |
[Simultaneous rapid determination of eight food additives in foods by reversed-phase high performance liquid chromatography].
Topics: Aspartame; Beverages; Chromatography, High Pressure Liquid; Food Additives; Food Preservation; Food Preservatives; Saccharin; Sorbic Acid | 2000 |
Estimated intake of the artificial sweeteners acesulfame-K, aspartame, cyclamate and saccharin in a group of Swedish diabetics.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aspartame; Beverages; Child; Child, Preschool; Cyclamates; Diabetes Mellitus; Diet; Female; Food; Humans; Infant; Male; Middle Aged; Saccharin; Surveys and Questionnaires; Sweden; Sweetening Agents; Thiazines | 2003 |
Receptors for bitter, sweet and umami taste couple to inhibitory G protein signaling pathways.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aspartame; Cell Line; Colforsin; Cyclamates; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Fructose; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pertussis Toxin; Phosphorylation; Receptors, G-Protein-Coupled; Saccharin; Sodium Glutamate; Sucrose; Taste; Taste Buds; Transducin; Tryptophan | 2004 |
[Analysis of nine kinds of sweeteners in foods by LC/MS].
Topics: Aspartame; Chromatography, High Pressure Liquid; Cyclamates; Diterpenes, Kaurane; Food Analysis; Glucosides; Glycyrrhizic Acid; Phenylurea Compounds; Saccharin; Spectrometry, Mass, Electrospray Ionization; Sucrose; Sweetening Agents; Thiazines | 2005 |
Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography.
Topics: Anion Exchange Resins; Aspartame; Carbonated Beverages; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Citrus; Cyclamates; Food Analysis; Fruit; Reproducibility of Results; Saccharin; Sweetening Agents; Thiazines | 2005 |
Daily intake assessment of saccharin, stevioside, D-sorbitol and aspartame from various processed foods in Korea.
Topics: Adolescent; Adult; Aged; Aspartame; Child; Child, Preschool; Chromatography, High Pressure Liquid; Diet; Diterpenes, Kaurane; Food Analysis; Glucosides; Humans; Infant; Korea; Middle Aged; Nutrition Surveys; Saccharin; Sorbitol; Sweetening Agents | 2005 |
Resolution of an intense sweetener mixture by use of a flow injection sensor with on-line solid-phase extraction. Application to saccharin and aspartame in sweets and drinks.
Topics: Aspartame; Beverages; Calibration; Chemistry, Physical; Chromatography, High Pressure Liquid; Dextrans; Flow Injection Analysis; Food Analysis; Hydrogen-Ion Concentration; Phosphates; Phosphoric Acids; Saccharin; Software; Spectrophotometry; Sweetening Agents | 2006 |
Enhancement of rat bladder contraction by artificial sweeteners via increased extracellular Ca2+ influx.
Topics: Adenosine Triphosphate; Animals; Aspartame; Atropine; Calcium; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rats; Rats, Wistar; Saccharin; Sweetening Agents; Thiazines; Urinary Bladder | 2006 |
High-dose chromium(III) supplementation has no effects on body mass and composition while altering plasma hormone and triglycerides concentrations.
Topics: Animals; Aspartame; Body Composition; Body Weight; Chromium; Eating; Insulin; Leptin; Male; Organ Size; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Saccharin; Triglycerides | 2006 |
Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aspartame; Beverages; Carbonated Beverages; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cyclamates; Denmark; Diet Surveys; Food Analysis; Humans; Infant; Maximum Allowable Concentration; Middle Aged; Saccharin; Sweetening Agents; Thiazines | 2007 |
Synthesis, characterization and antimycobacterial activity of Ag(I)-aspartame, Ag(I)-saccharin and Ag(I)-cyclamate complexes.
Topics: Anti-Bacterial Agents; Aspartame; Cyclamates; Humans; Ligands; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Organometallic Compounds; Saccharin; Silver | 2007 |
Sweeteners: how the brands measure up.
Topics: Animals; Aspartame; Carbohydrates; Consumer Behavior; Humans; Neoplasms; Rats; Saccharin; Sucrose; Sweetening Agents | 2007 |
Influence of artificial sweeteners on the kinetic and metabolic behavior of Lactobacillus delbrueckii subsp. bulgaricus.
Topics: Aspartame; Biomass; Culture Media; Cyclamates; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Lactobacillus delbrueckii; Models, Biological; Saccharin; Sweetening Agents; Yogurt | 2007 |
Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark, 2005.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartame; Beverages; Body Weight; Child; Child, Preschool; Cyclamates; Denmark; Diet Surveys; Female; Food Analysis; Humans; Infant; Male; Maximum Allowable Concentration; Middle Aged; Saccharin; Sex Factors; Sweetening Agents; Thiazines | 2008 |
Artificial sweetener consumption and urinary tract tumors in Cordoba, Argentina.
Topics: Aged; Argentina; Aspartame; Carcinoma, Transitional Cell; Case-Control Studies; Cyclamates; Female; Humans; Male; Middle Aged; Risk Factors; Saccharin; Sweetening Agents; Thiazines; Urologic Neoplasms | 2008 |
Simultaneous determination of saccharin and aspartame in commercial noncaloric sweeteners using the PLS-2 multivariate calibration method and validation by capillary electrophoresis.
Topics: Aspartame; Calibration; Electrophoresis, Capillary; Least-Squares Analysis; Models, Statistical; Multivariate Analysis; Saccharin; Spectrophotometry; Sweetening Agents | 2008 |
Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin.
Topics: Administration, Oral; Animals; Aspartame; Bone Marrow Cells; DNA Damage; DNA, Bacterial; Dose-Response Relationship, Drug; Male; Mice; Mutagens; Mutation; Saccharin; Salmonella typhimurium; Sweetening Agents; Thiazines | 2008 |
Letter to Fowler et al., 2008. No valid association between artificial sweeteners and weight gain.
Topics: Aspartame; Body Mass Index; Hispanic or Latino; Humans; Obesity; Reproducibility of Results; Risk Factors; Saccharin; Sweetening Agents; Weight Gain | 2009 |
Responses of single chorda tympani taste fibers of the calf (Bos taurus).
Topics: Animals; Aspartame; Cattle; Chorda Tympani Nerve; Nerve Fibers; Organic Chemicals; Quinine; Saccharin; Sodium Chloride; Sodium Glutamate; Sucrose; Sweetening Agents; Taste; Taste Buds; Taste Threshold | 2010 |
Stevia and saccharin preferences in rats and mice.
Topics: Animals; Aspartame; Cyclamates; Diterpenes, Kaurane; Drinking; Feeding Behavior; Female; Food Preferences; Glucosides; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; Saccharin; Species Specificity; Stevia; Sweetening Agents; Taste; Taste Threshold | 2010 |
Effects of artificial sweeteners on body weight, food and drink intake.
Topics: Animals; Aspartame; Behavior, Animal; Body Weight; Cyclamates; Drinking; Eating; Female; Male; Mice; Mice, Inbred CBA; Saccharin; Sweetening Agents; Thiazines; Time Factors | 2010 |
Aspartame-fed zebrafish exhibit acute deaths with swimming defects and saccharin-fed zebrafish have elevation of cholesteryl ester transfer protein activity in hypercholesterolemia.
Topics: Animals; Aspartame; Blood Glucose; Cholesterol Ester Transfer Proteins; Cholesterol, Dietary; Diet; Hypercholesterolemia; Saccharin; Sweetening Agents; Swimming; Zebrafish | 2011 |
[Influences of ion-suppressors on retention behaviors of nine food additives in reversed-phase high performance liquid chromatographic separation].
Topics: Aspartame; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Food Additives; Ions; Saccharin | 2011 |
Addition of sucralose enhances the release of satiety hormones in combination with pea protein.
Topics: Adult; Animals; Aspartame; Cell Line, Tumor; Cholecystokinin; Enteroendocrine Cells; Glucagon-Like Peptide 1; Humans; Male; Mice; Middle Aged; Pisum sativum; Plant Proteins; Rats; Saccharin; Satiation; Sucrose; Sweetening Agents; Thiazines; Young Adult | 2012 |
The black agonist-receptor model of high potency sweeteners, and its implication to sweetness taste and sweetener design.
Topics: Aspartame; Carrier Proteins; Databases, Factual; Humans; Models, Molecular; Receptors, G-Protein-Coupled; Saccharin; Sweetening Agents; Taste | 2011 |
Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds.
Topics: Amino Acid Motifs; Amino Acid Substitution; Aspartame; Binding Sites; Computer Simulation; Cyclamates; HEK293 Cells; Humans; Models, Molecular; Molecular Weight; Mutagenesis, Site-Directed; Receptors, G-Protein-Coupled; Saccharin; Sucrose; Sweetening Agents; Thiazines; Tryptophan | 2012 |
Functional characterization of the heterodimeric sweet taste receptor T1R2 and T1R3 from a New World monkey species (squirrel monkey) and its response to sweet-tasting proteins.
Topics: Animals; Aspartame; Benzene Derivatives; Humans; Plant Proteins; Protein Conformation; Protein Multimerization; Receptors, G-Protein-Coupled; Saccharin; Saimiri; Static Electricity; Sweetening Agents; Taste; Taste Perception | 2012 |
Saccharin and aspartame, compared with sucrose, induce greater weight gain in adult Wistar rats, at similar total caloric intake levels.
Topics: Animals; Aspartame; Energy Intake; Energy Metabolism; Male; Rats; Rats, Wistar; Saccharin; Satiation; Sucrose; Sweetening Agents; Weight Gain; Yogurt | 2013 |
The antimicrobial activity of the three commercially available intense sweeteners against common periodontal pathogens: an in vitro study.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Aspartame; Cariostatic Agents; Humans; Microbial Sensitivity Tests; Periodontal Diseases; Porphyromonas gingivalis; Saccharin; Sucrose; Sweetening Agents | 2012 |
Assessment of Korean consumer exposure to sodium saccharin, aspartame and stevioside.
Topics: Aspartame; Diterpenes, Kaurane; Environmental Exposure; Glucosides; Humans; Republic of Korea; Saccharin; Sweetening Agents | 2013 |
Risk assessment of additives through soft drinks and nectars consumption on Portuguese population: a 2010 survey.
Topics: Aspartame; Benzoic Acid; Beverages; Carbonated Beverages; Diet Surveys; Food Additives; Humans; Mineral Waters; No-Observed-Adverse-Effect Level; Plant Nectar; Portugal; Risk Assessment; Saccharin; Sweetening Agents; Thiazines | 2013 |
The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays.
Topics: Aspartame; Blood Cells; Endotoxins; Humans; Interleukin-10; Interleukin-6; Molasses; Phytohemagglutinins; Primary Cell Culture; Saccharin; Sucrose; Sweetening Agents | 2014 |
Effects of artificial sweeteners on the AhR- and GR-dependent CYP1A1 expression in primary human hepatocytes and human cancer cells.
Topics: Aspartame; Cell Line, Tumor; Cells, Cultured; Cyclamates; Cytochrome P-450 CYP1A1; Food-Drug Interactions; Hepatocytes; Humans; Receptors, Aryl Hydrocarbon; Receptors, Glucocorticoid; Saccharin; Sweetening Agents; Thiazines | 2013 |
Non-nutritive sweeteners: no class effect on the glycaemic or appetite responses to ingested glucose.
Topics: Adolescent; Appetite; Aspartame; Blood Glucose; Body Mass Index; Female; Gastrointestinal Tract; Glucose; Healthy Volunteers; Humans; Male; Non-Nutritive Sweeteners; Pilot Projects; Saccharin; Thiazines; Young Adult | 2014 |
[A rapid dialysis method for analysis of artificial sweeteners in food].
Topics: Aspartame; Chromatography, High Pressure Liquid; Dialysis; Food Analysis; Phenylurea Compounds; Saccharin; Sweetening Agents; Thiazines; Time Factors | 2014 |
Modified high-density lipoproteins by artificial sweetener, aspartame, and saccharin, showed loss of anti-atherosclerotic activity and toxicity in zebrafish.
Topics: Animals; Aspartame; Atherosclerosis; Cholesterol Ester Transfer Proteins; Embryo, Nonmammalian; Humans; Lipoproteins, HDL; Lipoproteins, HDL3; Lipoproteins, LDL; Macrophages; Male; Oxidative Stress; Reactive Oxygen Species; Saccharin; Sweetening Agents; Zebrafish | 2015 |
Artificial sweeteners induce glucose intolerance by altering the gut microbiota.
Topics: Animals; Anti-Bacterial Agents; Aspartame; Body Weight; Diet, High-Fat; Dietary Fats; Feces; Female; Gastrointestinal Tract; Germ-Free Life; Glucose; Glucose Intolerance; Humans; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Microbiota; Saccharin; Sucrose; Sweetening Agents; Waist-Hip Ratio | 2014 |
The effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cells.
Topics: Aspartame; Caco-2 Cells; Cell Survival; Colonic Neoplasms; Comet Assay; Cyclamates; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; HEK293 Cells; HT29 Cells; Humans; Intestinal Mucosa; Risk Assessment; Saccharin; Sucrose; Sweetening Agents; Thiazines; Time Factors | 2015 |
Fate of artificial sweeteners in wastewater treatment plants in New York State, U.S.A.
Topics: Aspartame; New York; Particulate Matter; Saccharin; Sewage; Sucrose; Sweetening Agents; Thiazines; Waste Disposal, Fluid; Wastewater | 2014 |
Sub-minute method for simultaneous determination of aspartame, cyclamate, acesulfame-K and saccharin in food and pharmaceutical samples by capillary zone electrophoresis.
Topics: Aspartame; Cyclamates; Electrolytes; Electrophoresis, Capillary; Food Analysis; Pharmaceutical Preparations; Saccharin; Sweetening Agents; Thiazines | 2015 |
Impact of aspartame and saccharin on the rat liver: Biochemical, molecular, and histological approach.
Topics: Animals; Antioxidants; Aspartame; Body Weight; Carcinogenesis; Down-Regulation; Gene Expression; Liver; Liver Function Tests; Male; Rats; Rats, Wistar; Saccharin; Sweetening Agents | 2015 |
Nonnutritive Sweeteners in Breast Milk.
Topics: Aspartame; Environmental Monitoring; Female; Humans; Lactation; Milk, Human; Non-Nutritive Sweeteners; Saccharin; Sucrose; Thiazines | 2015 |
Low-calorie sweeteners in food and food supplements on the Italian market.
Topics: Aspartame; Chromatography, Liquid; Cyclamates; Diet; Dietary Supplements; Dipeptides; Energy Intake; Food Additives; Food Contamination; Hesperidin; Humans; Italy; Saccharin; Sweetening Agents; Tandem Mass Spectrometry; Thiazines | 2015 |
Aspartame intake is associated with greater glucose intolerance in individuals with obesity.
Topics: Adult; Aged; Aspartame; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Energy Intake; Female; Fructose; Glucose Intolerance; Humans; Insulin Resistance; Male; Middle Aged; Non-Nutritive Sweeteners; Nutrition Surveys; Obesity; Saccharin; Sucrose | 2016 |
Occurrence of artificial sweeteners in human liver and paired blood and urine samples from adults in Tianjin, China and their implications for human exposure.
Topics: Adult; Aspartame; China; Cyclamates; Environmental Exposure; Female; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Saccharin; Sweetening Agents | 2016 |
Influence of Package Visual Cues of Sweeteners on the Sensory-Emotional Profiles of Their Products.
Topics: Adolescent; Adult; Aspartame; Color; Consumer Behavior; Cues; Diterpenes, Kaurane; Emotions; Female; Food Labeling; Food Packaging; Glucosides; Humans; Male; Non-Nutritive Sweeteners; Perception; Personal Satisfaction; Saccharin; Stevia; Sucrose; Sweetening Agents; Taste; Tea; Young Adult | 2017 |
Simultaneous determination of sodium saccharin, aspartame, acesulfame-K and sucralose in food consumed in Korea using high-performance liquid chromatography and evaporative light-scattering detection.
Topics: Aspartame; Chromatography, High Pressure Liquid; Dynamic Light Scattering; Food Analysis; Humans; Republic of Korea; Saccharin; Sucrose; Thiazines; Volatilization | 2017 |
Effect of Sweeteners on the Survival of Solenopsis invicta (Hymenoptera: Formicidae).
Topics: Animals; Ants; Aspartame; Dose-Response Relationship, Drug; Erythritol; Female; Insect Control; Insecticides; Larva; Male; Saccharin; Survival Rate; Sweetening Agents | 2017 |
A preliminary study on the application of natural sweet proteins in agar-based gels.
Topics: Agar; Aspartame; Beverages; Gels; Mutant Proteins; Plant Proteins; Saccharin; Sucrose; Sweetening Agents; Taste Perception; Time Factors | 2017 |
A Rapid Dialysis Method for Analysis of Artificial Sweeteners in Foods (2nd Report).
Topics: Aspartame; Calcium Carbonate; Chromatography, High Pressure Liquid; Citrates; Dialysis; Dialysis Solutions; Drug Combinations; Food Analysis; Hot Temperature; Hydrochloric Acid; Magnesium Oxide; Methanol; Phenylurea Compounds; Saccharin; Sodium Chloride; Sweetening Agents; Thiazines; Time Factors; Water | 2017 |
Safety assessment of 16 sweeteners for the Korean population using dietary intake monitoring and poundage method.
Topics: Aspartame; Diet; Food Additives; Humans; Republic of Korea; Saccharin; Sweetening Agents | 2017 |
Simultaneous determination of aspartame, cyclamate, saccharin and acesulfame-K in powder tabletop sweeteners by FT-Raman spectroscopy associated with the multivariate calibration: PLS, iPLS and siPLS models were compared.
Topics: Aspartame; Calibration; Chromatography, Liquid; Cyclamates; Food Analysis; Fourier Analysis; Least-Squares Analysis; Powders; Saccharin; Spectrum Analysis, Raman; Sweetening Agents; Tandem Mass Spectrometry; Thiazines | 2017 |
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study.
Topics: Animals; Aspartame; Avoidance Learning; Blood Glucose; Cell Count; Cognition; Drinking Water; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Lipid Peroxides; Male; Malondialdehyde; Memory; Neurons; Non-Nutritive Sweeteners; Rats, Sprague-Dawley; Saccharin; Sucrose; Weight Gain | 2018 |
Author's reply to comments from the International Sweeteners Association (ISA) in response to "Revisiting the safety of aspartame" by Arbind Kumar Choudhary and Etheresia Pretorius Nutrition Reviews 2017;75:718-730.
Topics: Aspartame; Humans; Nutritional Status; Saccharin; Sweetening Agents | 2018 |
Comments from the International Sweeteners Association (ISA) in response to "Revisiting the safety of aspartame" by Arbind Kumar Choudhary and Etheresia Pretorius Nutrition Reviews 2017;75:718-730.
Topics: Aspartame; Humans; Nutritional Status; Saccharin; Sweetening Agents | 2018 |
Consumption of non-caloric sweeteners among pregnant Chileans: a cross-sectional study.
Topics: Adult; Aspartame; Chile; Cross-Sectional Studies; Cyclamates; Diterpenes, Kaurane; Female; Glucosides; Humans; Non-Nutritive Sweeteners; Pregnancy; Pregnant Women; Recommended Dietary Allowances; Saccharin; Social Class; Sucrose; Thiazines | 2019 |
Prevalence of ethanol and other potentially harmful excipients in pediatric oral medicines: survey of community pharmacies in a Nigerian City.
Topics: Administration, Oral; Aspartame; Azo Compounds; Child; Dosage Forms; Ethanol; Excipients; Humans; Nigeria; Parabens; Pharmacies; Polysorbates; Propylene Glycol; Saccharin; Sodium Benzoate; Sorbitol; Sucrose; Surveys and Questionnaires | 2019 |
Commercially available non-nutritive sweeteners modulate the antioxidant status of type 2 diabetic rats.
Topics: Animals; Antioxidants; Aspartame; Catalase; Diabetes Mellitus, Type 2; Glutathione; Glutathione Reductase; Humans; Male; Non-Nutritive Sweeteners; Rats; Rats, Sprague-Dawley; Saccharin; Sucrose; Superoxide Dismutase | 2019 |
FTIR spectroscopy coupled with machine learning approaches as a rapid tool for identification and quantification of artificial sweeteners.
Topics: Aspartame; Beverages; Calibration; Chromatography, High Pressure Liquid; Cyclamates; Machine Learning; Principal Component Analysis; Saccharin; Spectroscopy, Fourier Transform Infrared; Sweetening Agents; Thiazines | 2020 |
Insights into the effect of artificial sweeteners on the structure, stability, and fibrillation of type I collagen.
Topics: Aspartame; Collagen Type I; Diabetes Mellitus; Fibril-Associated Collagens; Humans; Obesity; Saccharin; Sucrose; Sweetening Agents | 2020 |
Artificial sweeteners in non-alcoholic beverages: Occurrence and exposure estimation of the Portuguese population.
Topics: Adolescent; Adult; Aspartame; Beverages; Diet Surveys; Humans; Maximum Allowable Concentration; No-Observed-Adverse-Effect Level; Portugal; Saccharin; Sweetening Agents; Thiazines | 2020 |
Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria,
Topics: Aspartame; Bacterial Adhesion; Biofilms; Caco-2 Cells; Dose-Response Relationship, Drug; Enterococcus faecalis; Escherichia coli; Gastrointestinal Microbiome; Hemolysis; Humans; Saccharin; Sucrose; Sweetening Agents | 2021 |
Saccharin and Sucralose Protect the Glomerular Microvasculature In Vitro against VEGF-Induced Permeability.
Topics: Aspartame; Capillary Permeability; Diabetic Nephropathies; Endothelial Cells; Endothelium, Vascular; Humans; In Vitro Techniques; Kidney; Microvessels; Protective Agents; Saccharin; Sucrose; Sweetening Agents; Vascular Endothelial Growth Factors | 2021 |
Inhibitory Effects of Artificial Sweeteners on Bacterial Quorum Sensing.
Topics: Aspartame; Bacterial Proteins; Biosensing Techniques; Carboxylic Ester Hydrolases; Cell Communication; Gastrointestinal Microbiome; Gram-Negative Bacteria; Humans; Molecular Docking Simulation; Quorum Sensing; Saccharin; Sucrose; Sweetening Agents; Trans-Activators | 2021 |
Non-caloric artificial sweeteners exhibit antimicrobial activity against bacteria and promote bacterial evolution of antibiotic tolerance.
Topics: Anti-Bacterial Agents; Aspartame; Bacteria; Escherichia coli; Saccharin; Sweetening Agents | 2022 |
Chronic intake of nutritive sweeteners and saccharin increases levels of glycolytic and lipogenic enzymes in rat liver.
Topics: Acetyl-CoA Carboxylase; Animals; Aspartame; Fatty Acid Synthases; Female; Fructose; Glucagon; Glucokinase; Glucose; Insulin; Leptin; Liver; Male; Non-Nutritive Sweeteners; Nutritive Sweeteners; Pyruvate Kinase; Rats; Rats, Wistar; Saccharin; Sucrose; Sweetening Agents; Triglycerides | 2022 |
A comprehensive database of declared high-intensity sweeteners in Brazilian commercial products and updated exposure assessment.
Topics: Aspartame; Brazil; Cyclamates; Dietary Sugars; Diterpenes, Kaurane; Glucosides; Humans; Non-Nutritive Sweeteners; Saccharin; Sweetening Agents; Thiazines | 2022 |
No Association between Low-Calorie Sweetener (LCS) Use and Overall Cancer Risk in the Nationally Representative Database in the US: Analyses of NHANES 1988-2018 Data and 2019 Public-Use Linked Mortality Files.
Topics: Aspartame; Cross-Sectional Studies; Energy Intake; Female; Humans; Neoplasms; Nutrition Surveys; Saccharin; Sweetening Agents | 2022 |
[Non-caloric sweeteners consumption in the adult population of Argentina].
Topics: Adolescent; Adult; Aged; Argentina; Aspartame; Female; Humans; Male; Middle Aged; Saccharin; Sweetening Agents; Young Adult | 2022 |
Development and Relative Validation of a Food Frequency Questionnaire to Assess Non-Nutritive Sweeteners Intake among Pregnant Women in Santiago, Chile: A Pilot Study.
Topics: Adult; Aspartame; Chile; Female; Glucosides; Humans; Non-Nutritive Sweeteners; Pilot Projects; Pregnancy; Pregnant Women; Saccharin; Surveys and Questionnaires | 2023 |
Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia.
Topics: Aspartame; Environmental Monitoring; Fresh Water; Risk Assessment; Rivers; Saccharin; Serbia; Sweetening Agents; Wastewater; Water; Water Pollutants, Chemical | 2023 |
Long-term aspartame and saccharin intakes are related to greater volumes of visceral, intermuscular, and subcutaneous adipose tissue: the CARDIA study.
Topics: Adipose Tissue; Adiposity; Adult; Aspartame; Female; Humans; Male; Obesity; Saccharin; Sweetening Agents; Young Adult | 2023 |