Compounds > sabinene

Page last updated: 2024-08-22

sabinene and simvastatin

sabinene has been researched along with simvastatin in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	3 (42.86)	29.6817
2010's	1 (14.29)	24.3611
2020's	1 (14.29)	2.80

Authors

Authors	Studies
Kivistö, KT; Lilja, JJ; Neuvonen, PJ	2
Hagenbach, J; Jung, L; Koffel, JC; Ubeaud, G; Vandenschrieck, S	1
Lilja, JJ; Neuvonen, M; Neuvonen, PJ	1
Choi, HY; Ham, I; Jung, ED; Lee, J; Yang, G	1
Leopoldini, M; Malaj, N; Russo, N; Sindona, G; Toscano, M	1
Ampawong, S; Burana-Osot, J; Chantip, S; Isarangkul, D; Kanjanapruthipong, T; Kengkoom, K; Phattanawasin, P; Sotanaphun, U; Tirawanchai, N	1

Trials

3 trial(s) available for sabinene and simvastatin

Article	Year
Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5 Topics: Adult; Area Under Curve; Beverages; Citrus; Cross-Over Studies; Female; Food-Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Reference Values; Simvastatin	1998
Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4 Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Beverages; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Female; Food-Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Mixed Function Oxygenases; Reference Values; Simvastatin; Time Factors	2000
Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin. British journal of clinical pharmacology, 2004, Volume: 58, Issue:1 Topics: Adult; Anticholesteremic Agents; Citrus; Cross-Over Studies; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Simvastatin	2004

Other Studies

4 other study(ies) available for sabinene and simvastatin

Article	Year
In vitro inhibition of simvastatin metabolism in rat and human liver by naringenin. Life sciences, 1999, Volume: 65, Issue:13 Topics: Animals; Beverages; Citrus; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flavanones; Flavonoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Rats; Simvastatin	1999
Lipid lowering activity of Citri unshii pericarpium in hyperlipemic rats. Immunopharmacology and immunotoxicology, 2008, Volume: 30, Issue:4 Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Citrus; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Plant Extracts; Plant Structures; Rats; Rats, Sprague-Dawley; Simvastatin; Triglycerides	2008
On the inhibitor effects of bergamot juice flavonoids binding to the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) enzyme. Journal of agricultural and food chemistry, 2010, Oct-13, Volume: 58, Issue:19 Topics: Catalytic Domain; Citrus; Flavanones; Flavonoids; Fruit; Hesperidin; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Molecular; Molecular Structure; Simvastatin	2010
A combination extract of kaffir lime, galangal, and lemongrass maintains blood lipid profiles, hepatocytes, and liver mitochondria in rats with nonalcoholic steatohepatitis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 124 Topics: Alpinia; Animals; Antioxidants; Citrus; Cymbopogon; Hepatocytes; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Plant Extracts; Rats; Rats, Sprague-Dawley; Simvastatin	2020