Page last updated: 2024-08-22

sabinene and simvastatin

sabinene has been researched along with simvastatin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Kivistö, KT; Lilja, JJ; Neuvonen, PJ2
Hagenbach, J; Jung, L; Koffel, JC; Ubeaud, G; Vandenschrieck, S1
Lilja, JJ; Neuvonen, M; Neuvonen, PJ1
Choi, HY; Ham, I; Jung, ED; Lee, J; Yang, G1
Leopoldini, M; Malaj, N; Russo, N; Sindona, G; Toscano, M1
Ampawong, S; Burana-Osot, J; Chantip, S; Isarangkul, D; Kanjanapruthipong, T; Kengkoom, K; Phattanawasin, P; Sotanaphun, U; Tirawanchai, N1

Trials

3 trial(s) available for sabinene and simvastatin

ArticleYear
Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors.
    Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5

    Topics: Adult; Area Under Curve; Beverages; Citrus; Cross-Over Studies; Female; Food-Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Reference Values; Simvastatin

1998
Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin.
    Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4

    Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Beverages; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Female; Food-Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Mixed Function Oxygenases; Reference Values; Simvastatin; Time Factors

2000
Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:1

    Topics: Adult; Anticholesteremic Agents; Citrus; Cross-Over Studies; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Simvastatin

2004

Other Studies

4 other study(ies) available for sabinene and simvastatin

ArticleYear
In vitro inhibition of simvastatin metabolism in rat and human liver by naringenin.
    Life sciences, 1999, Volume: 65, Issue:13

    Topics: Animals; Beverages; Citrus; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flavanones; Flavonoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Rats; Simvastatin

1999
Lipid lowering activity of Citri unshii pericarpium in hyperlipemic rats.
    Immunopharmacology and immunotoxicology, 2008, Volume: 30, Issue:4

    Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Citrus; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Plant Extracts; Plant Structures; Rats; Rats, Sprague-Dawley; Simvastatin; Triglycerides

2008
On the inhibitor effects of bergamot juice flavonoids binding to the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) enzyme.
    Journal of agricultural and food chemistry, 2010, Oct-13, Volume: 58, Issue:19

    Topics: Catalytic Domain; Citrus; Flavanones; Flavonoids; Fruit; Hesperidin; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Molecular; Molecular Structure; Simvastatin

2010
A combination extract of kaffir lime, galangal, and lemongrass maintains blood lipid profiles, hepatocytes, and liver mitochondria in rats with nonalcoholic steatohepatitis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 124

    Topics: Alpinia; Animals; Antioxidants; Citrus; Cymbopogon; Hepatocytes; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Plant Extracts; Rats; Rats, Sprague-Dawley; Simvastatin

2020