sabarubicin has been researched along with epirubicin in 4 studies
| Studies (sabarubicin) | Trials (sabarubicin) | Recent Studies (post-2010) (sabarubicin) | Studies (epirubicin) | Trials (epirubicin) | Recent Studies (post-2010) (epirubicin) |
|---|---|---|---|---|---|
| 29 | 5 | 4 | 5,453 | 1,838 | 1,570 |
| Protein | Taxonomy | sabarubicin (IC50) | epirubicin (IC50) |
|---|---|---|---|
| Genome polyprotein | 0.75 | ||
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 5.181 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ghelardoni, S; Ronca, F; Ronca-Testoni, S; Yu, G; Zucchi, R | 1 |
| Animati, F; Calafiore, AM; Cipollone, A; Di Giammarco, G; Liberi, G; Licata, S; Maggi, CA; Manzini, S; Menna, P; Minotti, G; Saponiero, A | 1 |
| Menna, P; Minotti, G; Salvatorelli, E | 1 |
1 review(s) available for sabarubicin and epirubicin
| Article | Year |
|---|---|
In vitro modeling of the structure-activity determinants of anthracycline cardiotoxicity.
Topics: Alcohols; Animals; Anthracyclines; Antineoplastic Agents; Clinical Trials as Topic; Disaccharides; Doxorubicin; Drug Evaluation, Preclinical; Epirubicin; Heart; Humans; In Vitro Techniques; Models, Cardiovascular; Reactive Oxygen Species; Structure-Activity Relationship; Taxoids | 2007 |
3 other study(ies) available for sabarubicin and epirubicin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Effect of MEN 10755, a new disaccharide analogue of doxorubicin, on sarcoplasmic reticulum Ca(2+) handling and contractile function in rat heart.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Calcium; Calcium-Transporting ATPases; Disaccharides; Doxorubicin; Epirubicin; Heart; In Vitro Techniques; Male; Myocardial Contraction; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tritium | 2000 |
Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Disaccharides; Doxorubicin; Epirubicin; Heart Atria; Humans; Iron; Myocardium; Sulfur | 2000 |