Page last updated: 2024-09-03

s-trichlorovinyl-n-acetylcysteine and acetylcysteine

s-trichlorovinyl-n-acetylcysteine has been researched along with acetylcysteine in 6 studies

Compound Research Comparison

Studies
(s-trichlorovinyl-n-acetylcysteine)
Trials
(s-trichlorovinyl-n-acetylcysteine)
Recent Studies (post-2010)
(s-trichlorovinyl-n-acetylcysteine)
Studies
(acetylcysteine)
Trials
(acetylcysteine)
Recent Studies (post-2010) (acetylcysteine)
60014,5801,0465,960

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dekant, W; Henschler, D; Metzler, M1
Berthold, K; Dekant, W; Henschler, D; Schmidt, S; Vamvakas, S; Wild, D1
Bartels, MJ1
Birner, G; Dekant, W; Rutkowska, A1
Dekant, W; Friedewald, M; Lederer, E; Pähler, A; Parker, J; Völkel, W1
Dekant, W; Pähler, A; Völkel, W1

Other Studies

6 other study(ies) available for s-trichlorovinyl-n-acetylcysteine and acetylcysteine

ArticleYear
Identification of S-1,2,2-trichlorovinyl-N-acetylcysteine as a urinary metabolite of tetrachloroethylene: bioactivation through glutathione conjugation as a possible explanation of its nephrocarcinogenicity.
    Journal of biochemical toxicology, 1986, Volume: 1, Issue:2

    Topics: Acetylcysteine; Animals; Biotransformation; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Feces; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Glutathione Transferase; Kidney Neoplasms; Liver; Mice; Rats; Rats, Inbred Strains; Tetrachloroethylene

1986
Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Acetylation; Acetylcysteine; Alkenes; Animals; Bacterial Proteins; Biotransformation; Butadienes; Carbon-Sulfur Lyases; Cytosol; Kidney; Liver; Lyases; Male; Mutagenicity Tests; Rats; Salmonella typhimurium; Subcellular Fractions

1987
Quantitation of the tetrachloroethylene metabolite N-acetyl-S-(trichlorovinyl)cysteine in rat urine via negative ion chemical ionization gas chromatography/tandem mass spectrometry.
    Biological mass spectrometry, 1994, Volume: 23, Issue:11

    Topics: Acetylcysteine; Animals; Gas Chromatography-Mass Spectrometry; Hydroxylamines; Male; Rats; Rats, Inbred F344; Tetrachloroethylene

1994
N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine and 2,2,2-trichloroethanol: two novel metabolites of tetrachloroethene in humans after occupational exposure.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:1

    Topics: Acetylcysteine; Adult; Biotransformation; Chromatography, Gas; Ethylene Chlorohydrin; Female; Humans; Male; Mass Spectrometry; Middle Aged; Occupational Exposure

1996
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Biotransformation; Carcinogens; Dichloroacetic Acid; Environmental Pollutants; Female; Half-Life; Humans; Inhalation Exposure; Male; Middle Aged; Rats; Rats, Wistar; Solvents; Tetrachloroethylene; Trichloroacetic Acid

1998
Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins.
    Journal of chromatography. A, 1999, Jun-25, Volume: 847, Issue:1-2

    Topics: Acetylcysteine; Animals; Biomarkers; Biotransformation; DNA Damage; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Rats; Reference Standards; Sensitivity and Specificity; Tetrachloroethylene

1999