s-phenyl-n-acetylcysteine and thiodiacetic-acid

s-phenyl-n-acetylcysteine has been researched along with thiodiacetic-acid* in 1 studies

Other Studies

1 other study(ies) available for s-phenyl-n-acetylcysteine and thiodiacetic-acid

ArticleYear
[Determination of mercapturic acid in urine samples for the monitoring of occupational exposure to xenobiotics].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1989, Volume: 35, Issue:8

    The determination of mercapturic acids in urine samples of employees exposed to carcinogenic substances requires highly sensitive and specific methods such as GC/MS or HPLC/Fluorimetry. We applied GC/MS to the analysis of thiodiglycolic acid, which is an indicator metabolite of vinyl chloride exposure and of S-phenylmercapturic acid which can be used to control benzene exposure. S-cyanoethylmercapturic acid appears as a degradation product during acrylonitrile metabolism. This metabolite can be determined by HPLC combined with a sulfur specific fluorimetric detector. This procedure which is of general use offers the possibility to improve the biological monitoring in case of exposures to carcinogenic substances.

    Topics: Acetylcysteine; Carcinogens; Gas Chromatography-Mass Spectrometry; Humans; Thioglycolates; Xenobiotics

1989