s-methylthiocitrulline has been researched along with citrulline in 93 studies
| Studies (s-methylthiocitrulline) | Trials (s-methylthiocitrulline) | Recent Studies (post-2010) (s-methylthiocitrulline) | Studies (citrulline) | Trials (citrulline) | Recent Studies (post-2010) (citrulline) |
|---|---|---|---|---|---|
| 111 | 1 | 31 | 4,572 | 195 | 1,537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (21.51) | 18.2507 |
| 2000's | 46 (49.46) | 29.6817 |
| 2010's | 26 (27.96) | 24.3611 |
| 2020's | 1 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| Fast, W; Hu, S; Monzingo, AF; Robertus, JD; Schaller, TH; Wang, Y | 1 |
| Griffith, OW; Narayanan, K | 1 |
| Duffy, C; Furfine, ES; Garvey, EP; Harmon, MF; Hazelwood, R; Kiff, RJ; Knowles, RG; Oplinger, JA; Paith, JE; Salter, M | 1 |
| Makino, T; Miyauchi, T; Muto, A; Nabata, H; Nagafuji, T; Sugiyama, M | 1 |
| Griffith, OW; Joly, GA; Kilbourn, RG; Narayanan, K | 1 |
| Gozal, D; Gozal, E; Gozal, YM; Torres, JE | 1 |
| Conlon, SB; Sanders, KM; Shuttleworth, CW | 1 |
| Beal, MF; Matthews, RT; Yang, L | 1 |
| Czachurski, J; Seller, H; Zanzinger, J | 1 |
| Kimes, AS; London, ED; Vaupel, DB | 1 |
| Sandler, S; Sternesjö, J; Welsh, N | 1 |
| De Vries, R; Dzoljic, E; Dzoljic, MR | 1 |
| de Vries, R; Dzoljic, E; Dzoljic, MR; van Leeuwen, R | 1 |
| Dence, CS; McCarthy, TJ; Sherman, EL; Welch, MJ; Xu, M; Zhang, J | 1 |
| Dick, JM; Lefebvre, RA | 1 |
| Albin, R; Bazzett, T; Coppola, B; Geiger, A | 1 |
| Ichihara, A; Imig, JD; Inscho, EW; Navar, LG | 2 |
| Carrasco, V; Johnson, K; Pillsbury, HC; Prazma, J; Zdanski, CJ | 1 |
| Ichihara, A; Imig, JD; Navar, LG | 1 |
| Ichihara, A; Navar, LG | 1 |
| Jan, KY; Liu, F | 1 |
| Allison, KM; Anderson, S; Chapman, JG; Komers, R; Oyama, TT | 1 |
| Cooper, GR; Mialkowski, K; Wolff, DJ | 1 |
| Cheng, H; Harris, RC; McKanna, JA; Wang, J; Zhang, M | 1 |
| Gurr, JR; Jan, KY; Lai, HT; Lynn, S | 1 |
| Holt, PG; Sly, PD; Tulić, MK; Wale, JL | 1 |
| Cheng, HF; Harris, RC; McKanna, JA; Wang, JL; Zhang, MZ | 1 |
| Allison, KM; Anderson, S; Komers, R; Lindsley, JN; Oyama, TT | 1 |
| Ail, SF; Itzhak, Y; Martin, JL | 1 |
| Hayashi, M; Hirota, N; Ichihara, A; Saruta, T | 1 |
| Gauthier, S; Law, A; Quirion, R | 1 |
| Cervenka, L; Heller, J; Kramer, HJ; Malý, J | 1 |
| Bäcker, A; Bokemeyer, D; Cervenka, L; Kramer, HJ; Malý, J; Vanecková, I | 1 |
| Bäcker, A; Bader, M; Bokemeyer, D; Cervenka, L; Ganten, D; Kramer, HJ; Malý, J; Mitchell, KD; Vanecková, I | 1 |
| Deng, A; Thomson, SC | 1 |
| Almeida, MC; Branco, LG; Pelá, IR | 1 |
| Gulyaeva, NV; Gustafsson, MK; Moiseeva, YV; Onufriev, MV; Terenina, NB | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; March, JE; Valentin, JP; Wakefield, ID | 1 |
| Cao, L; Eldred, WD | 1 |
| Keegan, RD; Li, S; Quock, RM; Sorg, BA | 1 |
| Fujiki, T; Kubota, H; Morikawa, K; Morishita, T; Motoishi, M; Shimokawa, H; Takeshita, A; Talukder, MA; Tsutsui, M | 1 |
| Darvesh, AS; Gudelsky, GA; Yamamoto, BK | 1 |
| Anderson, S; Komers, R; Lindsley, JN; Oyama, TT | 1 |
| Badzyńska, B; Johns, EJ; Kompanowska-Jezierska, E; Sadowski, J; Walkowska, A | 1 |
| Eldred, WD; Yu, D | 1 |
| Hirakawa, H; Horiuchi, J; Kemuriyama, T; Nishida, Y; Sakamoto, H; Tandai-Hiruma, M | 1 |
| Ma, R; Wang, W; Zhu, GQ | 1 |
| Fast, W; Stone, EM | 1 |
| Jacquemond, V; Pouvreau, S | 1 |
| Bagnall, NM; Dent, PC; Johns, EJ; Sadowski, J; Walkowska, A | 1 |
| Costello, AL; Fast, W; Stone, EM; Tierney, DL | 1 |
| Barros, RC; Branco, LG; Cárnio, EC; Pereira, DH | 1 |
| Grzelec-Mojzesowicz, M; Sadowski, J | 1 |
| Blantz, RC; Deng, A | 1 |
| Alayza, RC; Beaudry, M; Duvallet, A; El Hasnaoui-Saadani, R; Favret, F; Launay, T; Léon-Velarde, F; Pichon, A; Quidu, P; Richalet, JP | 1 |
| Mitchell, KD; Mullins, JJ; Patterson, ME | 1 |
| Bie, P; Gramsbergen, JB; Johns, EJ; Kompanowska-Jezierska, E; Kuczeriszka, M; Walkowska, A; Wolff, H | 1 |
| Brett, SE; Casadei, B; Chowienczyk, PJ; Seddon, MD; Shah, AM | 1 |
| Janssen, PM; Kohr, MJ; Traynham, CJ; Wang, H; Wheeler, DG; Ziolo, MT | 1 |
| Agnew, C; Ding, Y; Li, YL; Schultz, HD | 1 |
| Chung, E; Ohgami, Y; Quock, RM; Shirachi, DY; Zelinski, LM | 1 |
| Kato, K; Kemuriyama, T; Maruyama, S; Nishida, Y; Ohta, H; Sato, Y; Tandai-Hiruma, M | 1 |
| Byrne, J; Casadei, B; Chowienczyk, P; Dworakowski, R; Jiang, B; Melikian, N; Seddon, M; Shabeeh, H; Shah, AM | 1 |
| Favret, F; Ge, RL; Jin, G; Marchant, D; Pichon, A; Richalet, JP; Shufeng, H; Zhenzhong, B | 1 |
| Fasching, A; Hansell, P; Källskog, O; Palm, F | 1 |
| Copp, SW; Hirai, DM; Musch, TI; Poole, DC; Schwagerl, PJ | 1 |
| Anderson, KL; Itzhak, Y; Kelley, JB | 1 |
| Ding, Y; Li, YL; Schultz, HD; Zheng, H | 1 |
| Casadei, B; Chowienczyk, PJ; Melikian, N; Seddon, MD; Shah, AM | 1 |
| Edlund, J; Fasching, A; Hansell, P; Liss, P; Palm, F | 1 |
| Gąsiorowska, A; Kompanowska-Jezierska, E; Kuczeriszka, M; Olszyński, KH; Sadowski, J | 1 |
| Altmann, SL; Anderson, KL; Itzhak, Y; Kelley, JB | 1 |
| Doherty, GH; Gaynor, S; Oldreive, CE | 1 |
| Fast, W; Linsky, T | 1 |
| Davies, W; Khraibi, A; Montgomery, S; Ratliff, BB; Rodebaugh, J; Sekulic, M; Solhaug, MJ | 1 |
| Argiolas, A; Melis, MR; Sanna, F; Succu, S | 1 |
| Kong, J; Li, J; Lu, J; Xing, J | 1 |
| Artinian, L; Rehder, V; Yang, H; Zhong, L | 1 |
| Copp, SW; Ferguson, SK; Hirai, DM; Holdsworth, CT; Musch, TI; Poole, DC | 1 |
| Balligand, JL; Carnicer, R; Casadei, B; Crabtree, MJ; Idigo, WO; Jayaram, R; Reilly, S; Zhang, MH; Zhang, YH | 1 |
| Hagisawa, K; Kato, K; Kemuriyama, T; Nishida, Y; Ohta, H; Tandai-Hiruma, M; Tashiro, A | 1 |
| Brett, S; Casadei, B; Chowienczyk, P; Melikian, N; Seddon, M; Shabeeh, H; Shah, AM | 1 |
| Copp, SW; Fels, RJ; Hirai, DM; Kenney, MJ; Musch, TI; Poole, DC; Sims, GE | 1 |
| Casadei, B; Chowienczyk, P; Dworakowski, R; Melikian, N; Shabeeh, H; Shah, AM | 1 |
| DeLorey, DS; Jendzjowsky, NG | 1 |
| Fujishima, S; Hasegawa, K; Hayashi, K; Homma, K; Hori, S; Itoh, H; Kanda, T; Saruta, T; Tatematsu, S; Tokuyama, H; Wakino, S | 1 |
| Broderick, JP; Clark, JF; Lu, A; Wagner, KR | 1 |
| Llorente, J; Mendiguren, A; Pineda, J; Santamarta, MT | 1 |
| Fu, Z; Go, A; Pamenter, ME; Powell, FL | 1 |
| Cui, X; Eichacker, PQ; Fitz, Y; Leppla, S; Li, Y; Moayeri, M; Ohanjanian, L; Sampath-Kumar, H; Suffredini, D; Xu, W | 1 |
| Brett, S; Casadei, B; Chowienczyk, PJ; Jiang, B; Khan, S; Melikian, N; Shabeeh, H; Shah, AM | 1 |
| Kim, SJ; Shao, YF; Sudarshan, VK; Wu, YN; Zhang, YH; Zhu, SC | 1 |
2 review(s) available for s-methylthiocitrulline and citrulline
| Article | Year |
|---|---|
Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption.
Topics: Absorption; Animals; Citrulline; Feedback; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Kidney Tubules; Nitric Oxide Synthase Type I; Signal Transduction; Sodium; Thiourea | 2007 |
Neuronal nitric oxide synthase and human vascular regulation.
Topics: Animals; Citrulline; Coronary Vessels; Enzyme Inhibitors; Forearm; Humans; Microcirculation; Microvessels; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Stress, Psychological; Thiourea; Vasodilation | 2009 |
91 other study(ies) available for s-methylthiocitrulline and citrulline
| Article | Year |
|---|---|
Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Topics: Amidines; Amidohydrolases; Crystallography, X-Ray; Drug Delivery Systems; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Ornithine; Recombinant Proteins; Substrate Specificity; Thiourea | 2009 |
Synthesis of L-thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline: a new class of potent nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Aminocaproates; Aminocaproic Acid; Animals; Binding Sites; Brain; Citrulline; Heme; Iron; Muscle, Smooth; Nitric Oxide Synthase; Rats; Thiourea | 1994 |
Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Binding Sites; Binding, Competitive; Cerebral Cortex; Citrulline; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Nitric Oxide Synthase; Rats; Thiourea; Time Factors | 1994 |
The neuroprotective effect of a potent and selective inhibitor of type I NOS (L-MIN) in a rat model of focal cerebral ischaemia.
Topics: Analysis of Variance; Animals; Arterial Occlusive Diseases; Cerebral Arteries; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Evaluation Studies as Topic; Ischemic Attack, Transient; Isoenzymes; Male; Neuroprotective Agents; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Thiourea | 1995 |
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents | 1995 |
Nitric oxide synthase isoforms and peripheral chemoreceptor stimulation in conscious rats.
Topics: Animals; Carotid Body; Chemoreceptor Cells; Citrulline; Drug Evaluation, Preclinical; Enzyme Inhibitors; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Stimulation, Chemical; Thiourea | 1996 |
Regulation of citrulline recycling in nitric oxide-dependent neurotransmission in the murine proximal colon.
Topics: Animals; Arginine; Citrulline; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Substrate Cycling; Synaptic Transmission; Thiourea | 1997 |
S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity.
Topics: Animals; Citrulline; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Malonates; MPTP Poisoning; Rats; Rats, Sprague-Dawley; Thiourea | 1997 |
Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs.
Topics: Animals; Arginine; Brain Stem; Citrulline; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hemodynamics; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine; Sympathetic Nervous System; Thiourea; Vagotomy | 1997 |
Further in vivo studies on attenuating morphine withdrawal: isoform-selective nitric oxide synthase inhibitors differ in efficacy.
Topics: Analysis of Variance; Animals; Blood Pressure; Citrulline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Guanidines; Heart Rate; Indazoles; Isoenzymes; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Substance Withdrawal Syndrome; Thiourea | 1997 |
S-methyl-L-thiocitrulline counteracts interleukin 1 beta induced suppression of pancreatic islet function in vitro, but does not protect against multiple low-dose streptozotocin-induced diabetes in vivo.
Topics: Animals; Cells, Cultured; Citrulline; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose; Insulin; Interleukin-1; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Streptozocin; Thiourea | 1997 |
Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase.
Topics: Animals; Anticonvulsants; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Imidazoles; Male; Mice; Nitric Oxide Synthase; Seizures; Thiourea | 1997 |
Vigilance and EEG power in rats: effects of potent inhibitors of the neuronal nitric oxide synthase.
Topics: Animals; Arousal; Child; Citrulline; Dimethyl Sulfoxide; Electroencephalography; Electromyography; Humans; Indazoles; Motor Activity; Neurons; Nitric Oxide Synthase; Rats; Rats, Wistar; Sleep; Thiourea | 1997 |
Synthesis, in vivo evaluation and PET study of a carbon-11-labeled neuronal nitric oxide synthase (nNOS) inhibitor S-methyl-L-thiocitrulline.
Topics: Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Citrulline; Enzyme Inhibitors; Female; Nitric Oxide Synthase; Papio; Rats; Rats, Sprague-Dawley; Thiourea; Tissue Distribution; Tomography, Emission-Computed | 1997 |
Influence of different classes of NO synthase inhibitors in the pig gastric fundus.
Topics: Animals; Biotin; Citrulline; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Isothiuronium; Lysine; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Swine; Thiourea | 1997 |
The neuronal NOS inhibitor L-MIN, but not 7-NINA, reduces neurotoxic effects of chronic intrastriatal administration of quinolinic acid.
Topics: Animals; Citrulline; Enzyme Inhibitors; Indazoles; Male; Microdialysis; Neostriatum; Neurotoxins; Nitric Oxide Synthase; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Thiourea | 1997 |
Neuronal nitric oxide synthase modulates rat renal microvascular function.
Topics: Acetazolamide; Acetylcholine; Angiotensin II; Animals; Arterioles; Citrulline; Enzyme Inhibitors; Kidney; Kidney Tubules, Distal; Male; Microcirculation; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Thiourea; Vasomotor System; Video Recording | 1998 |
Inhibition of nitric oxide synthase causes elevation of hearing thresholds.
Topics: Action Potentials; Animals; Auditory Threshold; Citrulline; Cochlea; Enzyme Inhibitors; Gerbillinae; Nitric Oxide Synthase; Synaptic Transmission; Thiourea | 1998 |
Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: interaction with neuronal NOS.
Topics: Acetazolamide; Animals; Arterioles; Citrulline; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Feedback; Isoenzymes; Juxtaglomerular Apparatus; Kidney Tubules; Kinetics; Loop of Henle; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nephrons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiourea; Vasoconstriction | 1998 |
Neuronal nitric oxide synthase-dependent afferent arteriolar function in angiotensin II-induced hypertension.
Topics: Acetazolamide; Angiotensin II; Animals; Arterioles; Blood Pressure; Citrulline; Enzyme Inhibitors; Hypertension; Juxtaglomerular Apparatus; Kidney Medulla; Male; Microscopy, Video; Muscle, Smooth, Vascular; Nephrons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Rats; Rats, Sprague-Dawley; Thiourea; Vasoconstriction; Vasodilation | 1999 |
Neuronal NOS contributes to biphasic autoregulatory response during enhanced TGF activity.
Topics: Acetazolamide; Animals; Arterioles; Citrulline; Feedback; Glomerular Mesangium; Kidney; Kidney Tubules; Male; Neurons; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Sprague-Dawley; Thiourea; Vasoconstrictor Agents | 1999 |
DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells.
Topics: Amitrole; Animals; Antioxidants; Aorta; Arsenites; Bacterial Proteins; Cadmium Chloride; Catalase; Cattle; Cells, Cultured; Chromans; Citrulline; Ditiocarb; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli Proteins; Free Radical Scavengers; Hydrogen Peroxide; Molsidomine; Mutagens; N-Glycosyl Hydrolases; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Phenanthrolines; Reactive Oxygen Species; Sodium Compounds; Sodium Selenite; Superoxide Dismutase; Superoxides; Thiomalates; Thiourea; Uric Acid | 2000 |
Effects of systemic inhibition of neuronal nitric oxide synthase in diabetic rats.
Topics: Animals; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Thiourea; Urination; Vascular Resistance | 2000 |
Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform.
Topics: Animals; Arginine; Calcium; Calmodulin; Cell Line; Citrulline; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Pituitary Gland; Rats; Substrate Specificity; Thiourea | 2000 |
Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Citrulline; Cyclooxygenase 2; Diet, Sodium-Restricted; Enzyme Inhibitors; Indazoles; Isoenzymes; Kidney; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Prostaglandin-Endoperoxide Synthases; Rats; Renin-Angiotensin System; RNA, Messenger; Thiourea | 2000 |
NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells.
Topics: Aorta; Arsenites; Arteriosclerosis; Cell Division; Cells, Cultured; Citrulline; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Membrane Transport Proteins; Multienzyme Complexes; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Phosphoproteins; Reactive Oxygen Species; RNA, Messenger; Teratogens; Thiourea; Transfection | 2000 |
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea | 2000 |
Nitric oxide regulates renal cortical cyclooxygenase-2 expression.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Citrulline; Cyclooxygenase 2; Dibutyryl Cyclic GMP; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Indazoles; Isoenzymes; Kidney Cortex; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride, Dietary; Thiourea | 2000 |
Role of neuronal nitric oxide synthase (NOS1) in the pathogenesis of renal hemodynamic changes in diabetes.
Topics: Animals; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; Thiourea; Vascular Resistance | 2000 |
nNOS inhibitors attenuate methamphetamine-induced dopaminergic neurotoxicity but not hyperthermia in mice.
Topics: Animals; Citrulline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fever; Indazoles; Male; Methamphetamine; Mice; Neostriatum; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Thiourea | 2000 |
Superoxide inhibits neuronal nitric oxide synthase influences on afferent arterioles in spontaneously hypertensive rats.
Topics: Animals; Citrulline; Cyclic N-Oxides; Enzyme Inhibitors; Juxtaglomerular Apparatus; Male; Microscopy, Video; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Penicillamine; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; S-Nitroso-N-Acetylpenicillamine; Spin Labels; Superoxides; Thiourea; Vasoconstriction | 2001 |
Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzoates; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Isoenzymes; Lysine; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiourea; Time Factors | 2001 |
Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Citrulline; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; Natriuresis; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Plasma Flow; Tetrazoles; Thiourea | 2001 |
Lack of a role of neuronal nitric oxide synthase in the regulation of the renal function in rats fed a low-sodium diet.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Diet, Sodium-Restricted; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Renin; RNA, Messenger; Sodium; Thiourea; Urodynamics | 2002 |
Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Citrulline; Denervation; Enzyme Inhibitors; Gene Expression Regulation; Hypertension; Kidney; Male; Matched-Pair Analysis; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Thiourea | 2002 |
Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback.
Topics: Animals; Citrulline; Cyclic GMP; Enzyme Inhibitors; Feedback, Physiological; Glomerular Filtration Rate; Guanylate Cyclase; Juxtaglomerular Apparatus; Male; Nephrons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Thiourea | 2003 |
Fever induced by platelet-derived growth factor, in contrast to fever induced by lipopolysaccharide, depends only on nitric oxide, but not on carbon monoxide pathway.
Topics: Animals; Becaplermin; Body Temperature; Carbon Monoxide; Citrulline; Deuteroporphyrins; Enzyme Inhibitors; Fever; Heme Oxygenase (Decyclizing); Isoenzymes; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Thiourea | 2003 |
Nitric oxide synthase activity in Fasciola hepatica: a radiometric study.
Topics: Animals; Arginase; Cattle; Citrulline; Enzyme Inhibitors; Fasciola hepatica; Guanidines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Radiometry; Thiourea; Valine | 2003 |
Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats.
Topics: Animals; Citrulline; Consciousness; Enzyme Inhibitors; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Thiourea; Vasoconstriction | 2003 |
Inhibitors of nitric oxide synthase block carbon monoxide-induced increases in cGMP in retina.
Topics: Animals; Carbon Monoxide; Citrulline; Cyclic GMP; Enzyme Inhibitors; Immunohistochemistry; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Retina; Thiourea; Turtles | 2003 |
The role of nitric oxide in locomotor regulation in mice and its interaction with nitrous oxide.
Topics: Animals; Citrulline; Male; Mice; Molsidomine; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrous Oxide; Thiourea | 2003 |
Up-regulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide synthase-deficient mice.
Topics: Animals; Bradykinin; Citrulline; Coronary Circulation; Coronary Vessels; Enzyme Inhibitors; Female; Immunohistochemistry; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Oxadiazoles; Thiourea; Up-Regulation; Vasodilation | 2004 |
Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain.
Topics: Animals; Brain Chemistry; Citrulline; Dopamine; Enzyme Inhibitors; Fever; Male; Malonates; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Serotonin; Serotonin Agents; Thiourea; Tyrosine | 2005 |
Effects of long-term inhibition of neuronal nitric oxide synthase (NOS1) in uninephrectomized diabetic rats.
Topics: Animals; Citrulline; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Cortex; Male; Nephrectomy; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Prostaglandin-Endoperoxide Synthases; Protective Agents; Proteinuria; Rats; Rats, Sprague-Dawley; Thiourea | 2004 |
Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases.
Topics: Animals; Citrulline; Electric Stimulation; Enzyme Inhibitors; Kidney; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renal Circulation; Thiourea; Vasodilator Agents | 2005 |
Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cadmium; Citrulline; Cyclic GMP; DEET; Dizocilpine Maleate; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; In Vitro Techniques; Molsidomine; Neural Inhibition; Nipecotic Acids; Nitric Oxide; Potassium; Retina; Silver Staining; Thiourea; Turtles; Vigabatrin | 2005 |
Brain neuronal nitric oxide synthase neuron-mediated sympathoinhibition is enhanced in hypertensive Dahl rats.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Injections, Intraventricular; Male; Medulla Oblongata; Nerve Tissue Proteins; Neural Inhibition; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pedunculopontine Tegmental Nucleus; Periaqueductal Gray; Raphe Nuclei; Rats; Rats, Inbred Dahl; Solitary Nucleus; Sympathetic Nervous System; Thiourea | 2005 |
Interaction of central Ang II and NO on the cardiac sympathetic afferent reflex in dogs.
Topics: Afferent Pathways; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Citrulline; Dogs; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Routes; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Female; Heart; Heart Rate; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reflex; Sympathectomy; Sympathetic Nervous System; Thiourea; Time Factors; Vagotomy | 2005 |
A continuous spectrophotometric assay for dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Animals; Citrulline; Humans; Hydrolysis; Rats; Spectrophotometry; Thiourea | 2005 |
Nitric oxide synthase inhibition affects sarcoplasmic reticulum Ca2+ release in skeletal muscle fibres from mouse.
Topics: Animals; Calcium; Citrulline; Enzyme Inhibitors; Hydrogen Peroxide; In Vitro Techniques; Indoles; Membrane Potentials; Mice; Mice, Inbred Strains; Muscle Fibers, Skeletal; Muscle, Skeletal; Nitric Oxide Synthase; Nitroarginine; Sarcoplasmic Reticulum; Thiourea | 2005 |
Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat.
Topics: Amidines; Anesthesia; Animals; Benzylamines; Citrulline; Diuresis; Electric Stimulation; Enzyme Inhibitors; Infusions, Intravenous; Kidney; Male; Natriuresis; Neuroeffector Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Sympathetic Nervous System; Thiourea | 2005 |
Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.
Topics: Amidohydrolases; Binding Sites; Citrulline; Cobalt; Cysteine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Lysine; Mass Spectrometry; Models, Chemical; omega-N-Methylarginine; Protons; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thiourea; X-Rays; Zinc | 2006 |
nNOS is involved in behavioral thermoregulation of newborn rats during hypoxia.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Body Temperature Regulation; Citrulline; Cold Temperature; Enzyme Inhibitors; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Thiourea; Time Factors | 2006 |
Renal tissue NO and intrarenal haemodynamics during experimental variations of NO content in anaesthetised rats.
Topics: Anesthesia; Animals; Blood Flow Velocity; Citrulline; Enzyme Inhibitors; Indazoles; Ion-Selective Electrodes; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Polarography; Rats; Rats, Wistar; Renal Circulation; Reproducibility of Results; S-Nitroso-N-Acetylpenicillamine; Thiourea; Time Factors | 2007 |
Brain stem NO modulates ventilatory acclimatization to hypoxia in mice.
Topics: Acclimatization; Animals; Blotting, Western; Brain Stem; Chronic Disease; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Hypoxia; Male; Mice; Mice, Inbred CBA; Nitric Oxide; Nitric Oxide Synthase Type I; Polymerase Chain Reaction; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Research Design; RNA, Messenger; Thiourea; Tidal Volume; Up-Regulation | 2007 |
Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Citrulline; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Hypertension, Malignant; Indoles; Kidney; Male; Nitric Oxide Synthase Type I; Rats; Regional Blood Flow; Renin; Sulfonamides; Thiourea; Vasoconstriction | 2008 |
Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats.
Topics: Animals; Blood Pressure; Citrulline; Consciousness; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Infusions, Intravenous; Kidney; Natriuresis; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Rats; Rats, Sprague-Dawley; Renin; Saline Solution, Hypertonic; Sympathectomy; Sympathetic Nervous System; Thiourea; Time Factors; Water-Electrolyte Balance | 2008 |
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System | 2008 |
Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban.
Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Calcium-Binding Proteins; Citrulline; Enzyme Inhibitors; Isoproterenol; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Phosphorylation; Sarcoplasmic Reticulum; Thiourea; Time Factors | 2008 |
Exercise training improves peripheral chemoreflex function in heart failure rabbits.
Topics: Action Potentials; Angiotensin II; Animals; Cardiac Pacing, Artificial; Carotid Body; Chronic Disease; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Exercise Therapy; Heart Failure; Hemodynamics; Hypoxia; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Physical Exertion; Rabbits; Receptor, Angiotensin, Type 1; Reflex; Signal Transduction; Sympathetic Nervous System; Thiourea | 2008 |
A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice.
Topics: Acetic Acid; Analgesia; Analysis of Variance; Animals; beta-Endorphin; Citrulline; Dynorphins; Enkephalin, Methionine; Enzyme Inhibitors; Hyperbaric Oxygenation; Injections, Intraperitoneal; Male; Mice; Microinjections; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Measurement; Thiourea | 2009 |
Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Brain; Citrulline; Enzyme Inhibitors; Heart Failure; Hypertension; Kidney; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pressoreceptors; Rats; Rats, Inbred Dahl; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Thiourea | 2009 |
Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo.
Topics: Adult; Citrulline; Coronary Circulation; Coronary Vessels; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Regional Blood Flow; Substance P; Thiourea; Vasodilation; Young Adult | 2009 |
Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine.
Topics: Acclimatization; Animals; Citrulline; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Exhalation; Haloperidol; Hypoxia; Inhalation; Lagomorpha; Male; Nitric Oxide Synthase Type I; Pulmonary Ventilation; Rats; Rats, Wistar; Respiratory Mechanics; Species Specificity; Thiourea; Tidal Volume; Time Factors | 2009 |
Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney.
Topics: Animals; Biological Transport; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Electrolytes; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred WF; Regional Blood Flow; Sodium; Thiourea | 2010 |
Effects of neuronal nitric oxide synthase inhibition on resting and exercising hindlimb muscle blood flow in the rat.
Topics: Animals; Blood Pressure; Citrulline; Enzyme Inhibitors; Heart Rate; Hindlimb; Male; Models, Animal; Muscle Contraction; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rest; Thiourea | 2010 |
Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice.
Topics: Animals; Citrulline; Conditioning, Psychological; Cyclic GMP; Fear; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Signal Transduction; Thiourea | 2010 |
Expression of neuronal nitric oxide synthase in rabbit carotid body glomus cells regulates large-conductance Ca2+-activated potassium currents.
Topics: Analysis of Variance; Animals; Body Weight; Calcium; Carotid Body; Chemoreceptor Cells; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Genetic Vectors; Green Fluorescent Proteins; Heart Failure; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Nitric Oxide Synthase Type I; Pacemaker, Artificial; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Rabbits; RNA, Messenger; Thiourea; Transduction, Genetic; Tyrosine 3-Monooxygenase | 2010 |
The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.
Topics: Acetophenones; Animals; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Male; NADPH Oxidases; Nitric Oxide Synthase Type I; Oxidative Stress; Oxygen Consumption; Rats; Rats, Inbred WF; Thiourea | 2010 |
Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake.
Topics: Animals; Arachidonic Acid; Blood Pressure; Citrulline; Cytochrome P-450 Enzyme System; Hemodynamics; Hydroxyeicosatetraenoic Acids; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Sodium, Dietary; Thiourea | 2011 |
Long-term memory of visually cued fear conditioning: roles of the neuronal nitric oxide synthase gene and cyclic AMP response element-binding protein.
Topics: Amygdala; Animals; Citrulline; Conditioning, Classical; Corticosterone; Cyclic AMP Response Element-Binding Protein; Fear; Memory, Long-Term; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molsidomine; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Phosphorylation; Photic Stimulation; Thiourea | 2011 |
Effects of nitric oxide on the survival and neuritogenesis of cerebellar Purkinje neurons.
Topics: Animals; Benzoates; Cell Count; Cells, Cultured; Cerebellar Cortex; Citrulline; Female; Imidazoles; Isothiuronium; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Tissue Proteins; Neurites; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Peroxynitrous Acid; Pregnancy; Purkinje Cells; Reactive Nitrogen Species; Thiourea | 2012 |
A continuous, fluorescent, high-throughput assay for human dimethylarginine dimethylaminohydrolase-1.
Topics: Amidohydrolases; Citrulline; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydrolysis; Kinetics; Sensitivity and Specificity; Thiourea | 2011 |
Neuronal nitric oxide synthase, nNOS, regulates renal hemodynamics in the postnatal developing piglet.
Topics: Age Factors; Animals; Animals, Newborn; Blood Pressure; Citrulline; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Infusions, Intra-Arterial; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Renal Artery; Renal Circulation; Swine; Thiourea; Vascular Resistance | 2012 |
Dopamine agonist-induced penile erection and yawning: differential role of D₂-like receptor subtypes and correlation with nitric oxide production in the paraventricular nucleus of the hypothalamus of male rats.
Topics: Animals; Apomorphine; Benzothiazoles; Calcium Channel Blockers; Citrulline; Dopamine Agonists; Dopamine Antagonists; Enzyme Inhibitors; Male; Microdialysis; Nitric Oxide; omega-Conotoxins; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Pramipexole; Rats; Receptors, Dopamine; Thiourea; Yawning | 2012 |
Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway.
Topics: Angiotensin I; Animals; Citrulline; Female; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Patch-Clamp Techniques; Peptide Fragments; Periaqueductal Gray; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Thiourea | 2012 |
Nitric oxide as intracellular modulator: internal production of NO increases neuronal excitability via modulation of several ionic conductances.
Topics: Action Potentials; Animals; Apamin; Calcium Channels; Citrulline; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Potassium Channel Blockers; Receptors, Cytoplasmic and Nuclear; Riluzole; Small-Conductance Calcium-Activated Potassium Channels; Snails; Sodium Channel Blockers; Sodium Channels; Soluble Guanylyl Cyclase; Thiourea | 2012 |
Effects of neuronal nitric oxide synthase inhibition on microvascular and contractile function in skeletal muscle of aged rats.
Topics: Acetylcholine; Aging; Animals; Citrulline; Enzyme Inhibitors; Hemodynamics; Male; Microcirculation; Models, Biological; Muscle Contraction; Muscle Strength; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxygen Consumption; Rats; Rats, Inbred BN; Rats, Inbred F344; Regional Blood Flow; Thiourea; Vasodilator Agents | 2012 |
Regulation of endothelial nitric-oxide synthase (NOS) S-glutathionylation by neuronal NOS: evidence of a functional interaction between myocardial constitutive NOS isoforms.
Topics: Animals; Arginase; Calcium Signaling; Citrulline; Enzyme Inhibitors; Heart Ventricles; Isoenzymes; Membrane Glycoproteins; Mice; Mice, Knockout; Muscle Proteins; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Phosphorylation; Receptors, Adrenergic, beta-3; Superoxides; Thiourea; Xanthine Dehydrogenase | 2012 |
High blood pressure enhances brain stem neuronal nitric oxide synthase activity in Dahl salt-sensitive rats.
Topics: Animals; Arterial Pressure; Brain Stem; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; Neurons; Nitric Oxide Synthase Type I; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Telemetry; Thiourea | 2013 |
Sympathetic activation increases NO release from eNOS but neither eNOS nor nNOS play an essential role in exercise hyperemia in the human forearm.
Topics: Adult; Blood Pressure; Citrulline; Forearm; Hand Strength; Humans; Hyperemia; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Exertion; Regional Blood Flow; Sympathetic Nervous System; Thiourea; Vasoconstriction | 2013 |
Neuronal nitric oxide synthase inhibition and regional sympathetic nerve discharge: implications for peripheral vascular control.
Topics: Action Potentials; Animals; Blood Pressure; Citrulline; Enzyme Inhibitors; Heart Rate; Kidney; Lumbosacral Region; Male; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Nerves; Sympathetic Nervous System; Thiourea | 2013 |
Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increases in cardiac workload.
Topics: Blood Pressure; Citrulline; Coronary Circulation; Coronary Vessels; Female; Heart Rate; Humans; Male; Middle Aged; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Thiourea; Vasodilation | 2013 |
Role of neuronal nitric oxide in the inhibition of sympathetic vasoconstriction in resting and contracting skeletal muscle of healthy rats.
Topics: Animals; Citrulline; Electric Stimulation; Enzyme Inhibitors; Hemodynamics; Hyperemia; Male; Muscle Contraction; Muscle, Skeletal; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Rest; Sympathetic Nervous System; Thiourea; Vasoconstriction | 2013 |
Rho-kinase contributes to pressure-induced constriction of renal microvessels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arterioles; Blood Pressure; Capillaries; Citrulline; Furosemide; Gadolinium; Kidney; Kidney Glomerulus; Male; Microcirculation; Muscle Development; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Thiourea | 2014 |
Administration of S-methyl-L-thiocitrulline protects against brain injuries after intracerebral hemorrhage.
Topics: Animals; Brain; Cell Death; Cerebral Hemorrhage; Citrulline; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Laminin; Male; Microvessels; Motor Activity; NADPH Dehydrogenase; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Occludin; Posture; Rats, Sprague-Dawley; Thiourea | 2014 |
Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.
Topics: Action Potentials; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ferricyanides; Indazoles; Locus Coeruleus; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Nitroprusside; Norepinephrine; Ornithine; Rats; Receptors, Opioid, mu; Thiourea | 2014 |
No evidence of a role for neuronal nitric oxide synthase in the nucleus tractus solitarius in ventilatory responses to acute or chronic hypoxia in awake rats.
Topics: Acclimatization; Animals; Central Nervous System; Citrulline; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Reflex; Respiration; Solitary Nucleus; Thiourea; Ventilation; Wakefulness | 2015 |
Nitric oxide production contributes to Bacillus anthracis edema toxin-associated arterial hypotension and lethality: ex vivo and in vivo studies in the rat.
Topics: Animals; Antigens, Bacterial; Aorta; Bacterial Toxins; Citrulline; Enzyme Inhibitors; Hypotension; In Vitro Techniques; Male; Mortality; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phenylephrine; Rats; Rats, Sprague-Dawley; Survival Rate; Thiourea; Vasoconstrictor Agents | 2016 |
Blood Pressure in Healthy Humans Is Regulated by Neuronal NO Synthase.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Citrulline; Dose-Response Relationship, Drug; Echocardiography; Enzyme Inhibitors; Healthy Volunteers; Heart Rate; Hemodynamics; Humans; Male; Nitric Oxide Synthase Type I; Thiourea; Young Adult | 2017 |
Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts.
Topics: Angiotensin II; Animals; Cells, Cultured; Citrulline; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Hypertension; Male; Malonates; Mitochondria, Heart; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Rotenone; Thiourea | 2020 |