Compounds > s-methyl diethylthiocarbamate
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s-methyl diethylthiocarbamate and ditiocarb

s-methyl diethylthiocarbamate has been researched along with ditiocarb in 5 studies

Compound Research Comparison

Studies
(s-methyl diethylthiocarbamate)		Trials
(s-methyl diethylthiocarbamate)		Recent Studies (post-2010)
(s-methyl diethylthiocarbamate)		Studies
(ditiocarb)		Trials
(ditiocarb)		Recent Studies (post-2010) (ditiocarb)
11131,89722224

Protein Interaction Comparison

ProteinTaxonomys-methyl diethylthiocarbamate (IC50)ditiocarb (IC50)
Gasdermin-DHomo sapiens (human)0.4
Gasdermin-DMus musculus (house mouse)0.4

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitson, TM1
Faiman, MD; Madan, A; Nagendra, SN1
Faiman, MD; Hart, BW1
Faiman, MD; Madan, A; Parkinson, A2

Other Studies

5 other study(ies) available for s-methyl diethylthiocarbamate and ditiocarb

ArticleYear
Effect of some thiocarbamate compounds on aldehyde dehydrogenase and implications for the disulfiram ethanol reaction.
    The Biochemical journal, 1991, Aug-15, Volume: 278 ( Pt 1)

    Topics: Aldehyde Dehydrogenase; Animals; Carbamates; Disulfides; Disulfiram; Ditiocarb; Kinetics; Liver; Sheep; Thiocarbamates

1991
S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase.
    Biochemical pharmacology, 1994, Apr-20, Volume: 47, Issue:8

    Topics: Aldehyde Dehydrogenase; Animals; Disulfiram; Ditiocarb; Male; Mitochondria, Liver; Oxidation-Reduction; Rats; Thiocarbamates

1994
Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aldehyde Dehydrogenase; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Ditiocarb; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Thiocarbamates

1993
Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Male; Microsomes, Liver; Oxygenases; Rats; Rats, Sprague-Dawley; Sulfoxides; Thiocarbamates

1993
Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:10

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Humans; Male; Microsomes, Liver; Rabbits; Rats; Thiocarbamates

1995