s-methyl diethylthiocarbamate has been researched along with disulfiram in 6 studies
Studies (s-methyl diethylthiocarbamate) | Trials (s-methyl diethylthiocarbamate) | Recent Studies (post-2010) (s-methyl diethylthiocarbamate) | Studies (disulfiram) | Trials (disulfiram) | Recent Studies (post-2010) (disulfiram) |
---|---|---|---|---|---|
11 | 1 | 3 | 3,776 | 175 | 723 |
Protein | Taxonomy | s-methyl diethylthiocarbamate (IC50) | disulfiram (IC50) |
---|---|---|---|
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 10.1 | |
Spike glycoprotein | Betacoronavirus England 1 | 9.35 | |
Replicase polyprotein 1ab | Betacoronavirus England 1 | 9.35 | |
type-1 angiotensin II receptor | Homo sapiens (human) | 6.637 | |
perilipin-5 | Homo sapiens (human) | 1.622 | |
perilipin-1 | Homo sapiens (human) | 6.959 | |
apelin receptor | Homo sapiens (human) | 2.63 | |
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 4.2905 | |
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | 85.03 | |
Transmembrane protease serine 2 | Homo sapiens (human) | 9.35 | |
Bile salt export pump | Homo sapiens (human) | 10 | |
Carbamate kinase | Giardia intestinalis | 0.6 | |
Retinal dehydrogenase 1 | Homo sapiens (human) | 0.13 | |
Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | 3.4 | |
Cytochrome P450 1A2 | Homo sapiens (human) | 4 | |
Procathepsin L | Homo sapiens (human) | 9.35 | |
Alpha-2A adrenergic receptor | Homo sapiens (human) | 4.904 | |
Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 1.3756 | |
Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
Replicase polyprotein 1ab | Human coronavirus 229E | 9.35 | |
Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
Adenosine receptor A3 | Homo sapiens (human) | 0.356 | |
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.9171 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.218 | |
D(1A) dopamine receptor | Homo sapiens (human) | 2.158 | |
D(4) dopamine receptor | Homo sapiens (human) | 3.15 | |
C-X-C chemokine receptor type 2 | Homo sapiens (human) | 6.013 | |
Mitogen-activated protein kinase 3 | Homo sapiens (human) | 1.51 | |
Protein-lysine 6-oxidase | Homo sapiens (human) | 0.32 | |
Lysine-specific demethylase 5A | Homo sapiens (human) | 10 | |
Caspase-1 | Homo sapiens (human) | 1.8 | |
Mu-type opioid receptor | Homo sapiens (human) | 3.511 | |
D(3) dopamine receptor | Homo sapiens (human) | 1.084 | |
Kappa-type opioid receptor | Homo sapiens (human) | 6.103 | |
C-C chemokine receptor type 2 | Homo sapiens (human) | 2.468 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
C-C chemokine receptor type 4 | Homo sapiens (human) | 8.395 | |
Gasdermin-D | Homo sapiens (human) | 0.4 | |
Lysyl oxidase homolog 3 | Homo sapiens (human) | 0.093 | |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
Sodium-dependent dopamine transporter | Homo sapiens (human) | 4.637 | |
NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 3 | |
Lysyl oxidase homolog 4 | Homo sapiens (human) | 0.059 | |
Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.6 | |
Monoglyceride lipase | Homo sapiens (human) | 0.8095 | |
Angiotensin-converting enzyme 2 | Homo sapiens (human) | 9.35 | |
Gasdermin-D | Mus musculus (house mouse) | 0.4 | |
Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 1.6 | |
Lysyl oxidase homolog 2 | Homo sapiens (human) | 0.15 | |
large T antigen | Betapolyomavirus macacae | 10.73 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (83.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kitson, TM | 1 |
Fauq, AH; Lipsky, JJ; Mays, DC; Naylor, S; Nelson, AN; Shriver, ZH; Veverka, KA | 1 |
Faiman, MD; Madan, A; Nagendra, SN | 1 |
Faiman, MD; Madan, A; Parkinson, A | 2 |
Hochreiter, J; Lapham, J; Ma, Q; McCance-Katz, EF; Morse, GD | 1 |
6 other study(ies) available for s-methyl diethylthiocarbamate and disulfiram
Article | Year |
---|---|
Effect of some thiocarbamate compounds on aldehyde dehydrogenase and implications for the disulfiram ethanol reaction.
Topics: Aldehyde Dehydrogenase; Animals; Carbamates; Disulfides; Disulfiram; Ditiocarb; Kinetics; Liver; Sheep; Thiocarbamates | 1991 |
S-methyl N,N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Disulfiram; Dithiothreitol; Enzyme Reactivators; Glutathione; Kinetics; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Sulfones; Thiocarbamates | 1995 |
S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Disulfiram; Ditiocarb; Male; Mitochondria, Liver; Oxidation-Reduction; Rats; Thiocarbamates | 1994 |
Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate.
Topics: Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Male; Microsomes, Liver; Oxygenases; Rats; Rats, Sprague-Dawley; Sulfoxides; Thiocarbamates | 1993 |
Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Humans; Male; Microsomes, Liver; Rabbits; Rats; Thiocarbamates | 1995 |
Disulfiram metabolite S-methyl-N,N-diethylthiocarbamate quantitation in human plasma with reverse phase ultra performance liquid chromatography and mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Disulfiram; Drug Stability; Humans; Mass Spectrometry; Reproducibility of Results; Thiocarbamates | 2012 |