Compounds > s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea

s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea and thiourea

s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea has been researched along with thiourea in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frick, LW; Furfine, ES; Garvey, EP; Lee, S; Oplinger, JA; Shearer, BG1
Cooper, GR; Mialkowski, K; Wolff, DJ1
Campillo, NE; Castaño, T; Castro, A; Encinas, A; Gil, C; Pérez, C1
Furukawa, A; Hisano, S; Kato, S; Koriyama, Y; Ogai, K; Sugitani, K1
Hisano, S; Kato, S; Koriyama, Y; Ogai, K; Sugitani, K1

Other Studies

5 other study(ies) available for s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea and thiourea

ArticleYear
Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity.
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Animals; Arginine; Binding, Competitive; Brain; Citrulline; Enzyme Inhibitors; Humans; Isoenzymes; Molecular Structure; Neurons; Nitric Oxide Synthase; Rats; Structure-Activity Relationship; Thiourea

1997
Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform.
    Archives of biochemistry and biophysics, 2000, Mar-01, Volume: 375, Issue:1

    Topics: Animals; Arginine; Calcium; Calmodulin; Cell Line; Citrulline; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Pituitary Gland; Rats; Substrate Specificity; Thiourea

2000
Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Drug Design; Enzyme Inhibitors; Isoenzymes; Neural Networks, Computer; Nitric Oxide Synthase Type I; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Thiadiazoles; Thiourea

2008
Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice.
    Journal of pharmacological sciences, 2015, Volume: 127, Issue:3

    Topics: Animals; Cell Death; Enzyme Inhibitors; Male; Methylnitrosourea; Mice, Inbred C57BL; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Synthase Type I; Photoreceptor Cells; Retinal Degeneration; Thiourea

2015
Nitric Oxide Synthase Activation as a Trigger of N-methyl-N-nitrosourea-Induced Photoreceptor Cell Death.
    Advances in experimental medicine and biology, 2016, Volume: 854

    Topics: Alkylating Agents; Animals; Apoptosis; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intraperitoneal; Male; Methylnitrosourea; Mice, Inbred C57BL; NADPH Dehydrogenase; Nitric Oxide Synthase Type I; Photoreceptor Cells, Vertebrate; Retina; Retinal Degeneration; Retinal Photoreceptor Cell Inner Segment; Thiourea

2016