s-adenosylmethionine has been researched along with vitamin b 12 in 194 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (24.23) | 18.7374 |
| 1990's | 29 (14.95) | 18.2507 |
| 2000's | 34 (17.53) | 29.6817 |
| 2010's | 60 (30.93) | 24.3611 |
| 2020's | 24 (12.37) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, AI | 1 |
| DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS | 1 |
| Arigoni, D | 1 |
| Kass, L; Peters, CL; Toler, LA | 1 |
| Cheh, A; Dizikes, LJ; Lakowicz, JR; Rakow, S; Ridley, WP; Wood, JM | 1 |
| Chrin, LR; Jaffe, JJ | 1 |
| Dizikes, LJ; Ridley, WP; Wood, JM | 1 |
| Fukui, S; Sugimoto, Y; Toraya, T | 1 |
| Lee, S; Scott, AI | 1 |
| Avogaro, P; Bellobuono, A; Bernardi, M; Corazza, GR; D'Ambro, A; Dioguardi, N; Gasbarrini, G; Ideo, G; Labo, G; Miglio, F; Pasquino, M | 1 |
| Corazza, GR; D'Ambro, A; Gasbarrini, G; Miglio, F; Stefanini, GF | 1 |
| Beuhring, KU; Shin, YS; Stokstad, EL | 1 |
| Atshaves, BP; Iida, K; Ozaki, S; Roessner, CA; Santander, PJ; Scott, AI; Stolowich, NJ; Warren, MJ | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Bell, IR; Berkes, S; Morrow, FD; Perrone, G; Read, M | 1 |
| Dirheimer, G; Keith, G; Pfohl-Leszkowicz, A | 1 |
| Blanche, F; Debussche, L; Thibaut, D | 1 |
| Arenson, E; Begley, JA; Chu, RC; Hall, CA; Lindenbaum, RH | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 2 |
| Horne, DW | 1 |
| Banerjee, RV; Dunham, WR; Frasca, V; Matthews, RG; Sands, RH | 1 |
| Runciman, WB; Snoswell, AM; Xue, GP | 1 |
| Liteplo, RG | 1 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Amess, JA; Amos, RJ; Sourial, NA | 1 |
| Buchet, JP; Lauwerys, R | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Stokstad, EL; Vidal, AJ | 1 |
| Inukai, S; Sato, K; Shimizu, S | 1 |
| Hanna, ML; Hutton, JJ; Taylor, RT | 1 |
| Decter, JB; Mansouri, A; Silber, R | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H | 1 |
| Flavin, M; Savin, MA; Slaughter, C | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Königk, E; Ossikovski, E; Schmidt, G | 1 |
| Cushley, RJ; Scott, AI; Townsend, CA | 1 |
| Lee, E; Scott, AI; Yagen, B | 1 |
| Ordóñez, LA; Wurtman, RJ | 2 |
| Taylor, RT; Weissbach, H | 1 |
| Mangum, JH; North, JA | 1 |
| Curri, SB | 1 |
| Demain, AL; White, RF | 1 |
| Carney, MW; Reynolds, EH; Toone, BK | 1 |
| Abels, J; Kroes, AC; Lindemans, J | 1 |
| Metz, J; van der Westhuyzen, J | 1 |
| Chanarin, I; Deacon, R; Jennings, P; Lumb, M; Perry, J; Purkiss, P; Sharer, N | 1 |
| Kal'nev, VR; Kanopkaĭte, SI; Rachkus, IuA | 1 |
| Lee, SL | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| Akaike, A; Sato, Y; Tamura, Y; Yokota, T | 1 |
| Stubbe, J | 1 |
| Drummond, JT; Matthews, RG | 1 |
| Blanche, F; Cameron, B; Crouzet, J; Debussche, L; Thibaut, D | 1 |
| Blumenthal, RM; Drummond, JT; Huang, S; Matthews, RG | 1 |
| Min, C; Ozaki, SI; Roessner, CA; Scott, AI; Spencer, JB; Stolowich, NJ | 1 |
| Metz, J | 1 |
| May, BA | 1 |
| Belozerova, EV; Iurkevich, AM; Kliasheva, RI; Nikol'skaia, II; Sharkova, EV | 1 |
| Delnomdedieu, M; Styblo, M; Thomas, DJ | 1 |
| Dixon, MM; Huang, S; Ludwig, M; Matthews, RG | 1 |
| Dunham, WR; Hoover, DM; Jarrett, JT; Ludwig, ML; Matthews, RG; Sands, RH | 1 |
| Akaike, A; Honda, Y; Kaneda, K; Kashii, S; Kikuchi, M; Tamura, Y | 1 |
| Goulding, CW; Matthews, RG; Postigo, D | 1 |
| Kawata, T; Maekawa, A; Tobimatsu, T; Toraya, T; Wada, M; Yamada, K | 1 |
| Levillayer, F; Rambach, A; Raux, E; Thermes, C; Warren, MJ; Woodcock, SC | 1 |
| Huang, S; Jarrett, JT; Matthews, RG | 1 |
| Raux, E; Schubert, HL; Warren, MJ; Wilson, KS; Woodcock, SC | 1 |
| Guiloff, RJ; Tan, SV | 1 |
| Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL | 1 |
| Hoover, DM; Jarrett, JT; Ludwig, ML; Matthews, RG | 1 |
| Ekblom, J; Löfberg, C; Oreland, L; Yassin, MS | 1 |
| Ekblom, J; Gottfries, CG; Oreland, L; Xilinas, M; Yassin, MS | 1 |
| Scott, JM; Weir, DG | 1 |
| Chazerain, P; Moulonguet, A; Olivero de Rubiana, JP; Vinciguerra, C; Ziza, JM | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| Brand, GM; Duthie, SJ; Grant, G; Narayanan, S | 1 |
| Becker, A; Surdin-Kerjan, Y; Thomas, D | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Hall, DA; Matthews, RG; Stasik, CN; Stevens, SY; Vander Kooi, CW; Zuiderweg, ER | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Varela-Moreiras, G | 1 |
| Capdevila, A; Kerins, DM; Koury, MJ; Rana, S; Wagner, C | 1 |
| Bandarian, V; Huddler, DP; Lennon, BW; Ludwig, ML; Matthews, RG; Pattridge, KA | 1 |
| Bottiglieri, T; Di Rocco, A; Geraci, A; Godbold, J; Morgello, S; Simpson, D; Werner, P | 1 |
| Becker, A; Bouter, LM; de Meer, K; Dekker, JM; Heine, RJ; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Stehouwer, CD; Struys, EA; Teerlink, T | 1 |
| Carmel, R; James, SJ; Melnyk, S | 1 |
| Bandarian, V; Ludwig, ML; Matthews, RG | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Stehouwer, CD; Teerlink, T; Zweegman, S | 1 |
| BALDESSARINI, RJ | 1 |
| Block, MA; Curien, G; Douce, R; Jabrin, S; Ravanel, S; Rébeillé, F; Rippert, P | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Spijkerman, AM; Stehouwer, CD; Teerlink, T | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Toohey, JI | 1 |
| Allen, RH; Dolce, ET; Johnson, MA; Stabler, SP | 1 |
| Jowitt, TA; Leys, D; Marshall, KR; Scrutton, NS; Toogood, HS; Wolthers, KR | 1 |
| Di Rocco, A; Werner, P | 1 |
| Allen, RH; Barbosa, PR; Braga, RC; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Machado, AL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Herrmann, W; Obeid, R | 1 |
| Huang, S; Lesley, SA; Ludwig, M; Matthews, RG; Pattridge, K; Romanchuk, G; Wilson, IA | 1 |
| Alberto, JM; Audonnet-Blaise, S; Blaise, SA; Daval, JL; Guéant, JL | 1 |
| Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R | 1 |
| Allen, RH; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Lopreato, FR; Robi, DL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Llanos, M; Montequin, MJ; Pinardi, G; Ronco, AM | 1 |
| Brunold, TC; Datta, S; Liptak, MD; Matthews, RG | 1 |
| Fuchs, G; Gaylor, DW; Hubanks, A; James, SJ; Jernigan, S; Melnyk, S; Pavliv, O; Reid, T | 1 |
| de Jonge, R; de Vries, JH; Eijkemans, MJ; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Meurs, JB | 1 |
| Devlin, AM; Green, TJ; Innis, SM; McMahon, JA; Skeaff, CM; Venn, BJ; Williams, SM | 1 |
| Chan, A; Kotyla, E; Lepore, A; Remington, R; Shea, TB; Zemianek, J | 1 |
| Fujita, T; Inui, H; Misono, H; Miyamoto, E; Nakano, Y; Ohnishi, K; Shigeoka, S; Tanioka, Y; Watanabe, F; Yabuta, Y; Yamaji, R | 1 |
| Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S | 1 |
| Demick, JM; Lanzilotta, WN | 1 |
| Ho, V; King, WD; Massey, TE | 1 |
| Allen, KD; Chen, BS; Helms, GL; Hu, K; Wang, SC; Werner, WJ | 1 |
| Liu, W; van der Donk, WA; Zhang, Q | 1 |
| Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL | 1 |
| Croft, AK; Dowling, DP; Drennan, CL | 1 |
| Sivolap, IuP | 1 |
| Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM | 1 |
| Alberto, JM; Gkikopoulou, E; Guéant, JL; Marguerite, V; Merten, M | 1 |
| Benjdia, A; Berteau, O; Guillot, A; Langella, P; Pierre, S; Sandström, C | 1 |
| Cacciapuoti, F | 1 |
| Grashin, RA; Poliakova, AV; Telichko, IN | 1 |
| Chan, KK; O'Hagan, D; Thompson, S | 1 |
| Bottiglieri, T | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Kim, HJ; LeVieux, J; Liu, HW; Liu, YN; Mansoorabadi, SO; McCarty, RM; Ogasawara, Y | 1 |
| Bessho, Y; Padmanabhan, B; Yokoyama, S | 1 |
| da Cunha, SF; de Freitas, EC; Deminice, R; Franco, GS; Jordao, AA; Rosa, FT | 1 |
| Gröber, U; Kisters, K; Schmidt, J | 1 |
| Rogers, E; Shea, TB | 1 |
| Caudy, AA; MacNeil, LT; Ritter, AD; Rosebrock, AP; Walhout, AJ; Watson, E; Yilmaz, LS | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Agamme, AL; D'Almeida, V; da Silva, VC; Fernandes, L; Guerra Shinohara, EM; Haseyama, EJ; Muniz, MT | 1 |
| de la Garza, AL; Haslberger, AG; Lovrecic, L; Martinez, AJ; Migliore, L; Milagro, FI; Peterlin, B; Remely, M | 1 |
| Blaszczyk, AJ; Booker, SJ; Buller, AR; Grove, TL; Lloyd, EP; Marous, DR; Moshos, KA; Townsend, CA | 1 |
| Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C | 1 |
| Blaszczyk, AJ; Booker, SJ; Elliott, SJ; Kelly, WL; Krebs, C; Lanz, ND; Maiocco, SJ; Silakov, A; Zhang, B | 1 |
| Deth, R; Hodgson, N; Trivedi, M; Zhang, Y | 1 |
| Broderick, JB; Broderick, WE; Duschene, KS; Hoffman, BM; Horitani, M; Hutcheson, RU; Marts, AR; Shisler, K | 1 |
| Kornhuber, J; Lewczuk, P; Linnebank, M; Oikonomidi, A; Popp, J; Semmler, A; Smulders, Y | 1 |
| Benjdia, A; Berteau, O; Chartier, G; Guillot, A; Leprince, J; Parent, A | 1 |
| Baumann, S; Begley, TP; Müller, R; Schnell, B; Wang, Y | 1 |
| Bridwell-Rabb, J; Drennan, CL | 1 |
| Bridwell-Rabb, J; Drennan, CL; Liu, HW; Sun, HG; Zhong, A | 1 |
| Eguchi, T; Kim, SY; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| Blaszczyk, AJ; Booker, SJ; Ho, JV; Silakov, A; Wang, B | 1 |
| Blaszczyk, AJ; Booker, SJ; Wang, RX | 1 |
| Kim, HJ; Liu, HW; Liu, YN; McCarty, RM | 1 |
| Blaszczyk, AJ; Booker, SJ; Jones, BS; Lanz, ND; McCarthy, EL; Wang, B; Wang, RX | 1 |
| McCully, KS | 1 |
| Brosnan, JT; Brosnan, ME; Clow, KA; MacMillan, L; Randell, EW; Tingley, G; Young, SK | 1 |
| Bridwell-Rabb, J; Drennan, CL; Grell, TAJ | 1 |
| Eguchi, T; Hammerschmidt, F; Kudo, F; Kuzuyama, T; Sato, S | 1 |
| McLaughlin, MI; van der Donk, WA | 1 |
| Alberto, JM; Battaglia-Hsu, SF; Coelho, D; Dreumont, N; Gauchotte, G; Ghemrawi, R; Guéant, JL; Hergalant, S; Houlgatte, R; Jung, M; Mosca, P; Ndiongue, M; Paoli, J; Quadros, EV; Robert, A; Sequeira, JM; Umoret, R | 1 |
| Blaesi, EJ; Blaszczyk, AJ; Booker, SJ; Knox, HL; Krebs, C; Wang, B; Wang, RX; Zhou, S | 1 |
| Wang, SC | 1 |
| Begley, TP; Müller, R; Schnell, B; Wang, Y | 1 |
| Feng, H; Gui, L; Li, N; Liu, Z; Ruan, M; Wan, JM; Wang, H; Zhang, H; Zhang, S | 1 |
| Abdelwahed, SH; Begley, TP; Britt, RD; Gagnon, DM; Mehta, AP; Stich, TA | 1 |
| Amaral, MS; Arni, RK; Coronado, MA; de Moraes, FR; Eberle, RJ; Olivier, DS; Peinado, RDS | 1 |
| Booker, SJ; Laremore, TN; Miller, DV; Radle, MI | 1 |
| Blaszczyk, AJ; Booker, SJ; Knox, HL | 1 |
| Deng, J; Dong, H; Shen, Y; Xie, Z; Xiong, L; Zhang, P; Zhao, G | 1 |
| Jarrett, JT | 1 |
| Blaszczyk, AJ; Booker, SJ; Chen, PY; Drennan, CL; Grove, TL; Knox, HL; Mukherjee, A; Schwalm, EL; Wang, B | 1 |
| Bharadwaj, B; Dhiman, P; Pillai, RR; Premkumar, N; Rajendiran, S; Ranjan, VP; Wilson, AB | 1 |
| Hammerschmidt, F; McLaughlin, MI; Pallitsch, K; van der Donk, WA; Wallner, G | 1 |
| Blue, TC; Davis, KM | 1 |
| Broderick, JB; Broderick, WE; McDaniel, EC; Moody, JD; Shepard, EM; Villanueva, M; Walls, WG | 1 |
| Kim, R; Nijhout, HF; Reed, MC | 1 |
| Benjdia, A; Bernardo-García, N; Berteau, O; Brewee, C; Chavas, LMG; Fradale, L; Fyfe, CD; Grimaldi, S; Guillot, A; Legrand, P | 1 |
| Boal, AK; Booker, SJ; Knox, HL; Sinner, EK; Townsend, CA | 1 |
| Dong, M; Li, Y; Tian, C; Yao, Y; Yu, L | 1 |
| Benjdia, A; Berteau, O; Brewee, C; Guillot, A; Guinchard, X; Haumann, M; Kubiak, X; Sabat, N; Soualmia, F | 1 |
| Drennan, CL; Ulrich, EC | 1 |
| Andexer, JN; Friedrich, T; Gagsteiger, J; Gericke, L; Heidinger, L; Jahn, S; Layer, G; Loenarz, C | 1 |
| Sinner, EK; Townsend, CA | 1 |
| Booker, SJ; Knox, HL | 1 |
| Eguchi, T; Kudo, F; Sato, S | 1 |
| Lee, YH; Liu, HW | 1 |
| Bridwell-Rabb, J; Dill, Z; Li, B | 1 |
| Chen, F; Guo, L; Li, H; Li, W; Liu, Q; Wei, Y; Wu, L; Xia, H; Xu, Y; Ye, F; Zhang, G; Zhang, J | 1 |
| Fan, PH; Geng, Y; Lee, YH; Liu, HW; Romo, AJ; Yeh, YC; Zhang, J; Zhong, A | 1 |
| Beltrán, LJ; Bulleid, NJ; Johnstone, IL; Page, AP; Tjahjono, E; Winter, AD | 1 |
| Eguchi, T; Hamano, Y; Hashimoto, J; Kozone, I; Kudo, F; Maruyama, C; Minato, A; Nagano, N; Sato, S; Shin-Ya, K | 1 |
| Boerries, M; Klett, H; Michels, KB; van Otterdijk, SD | 1 |
| Fan, Q; Feng, W; Guo, Z; Hao, L; Ju, M; Sun, X; Wang, L; Xiao, R; Yu, H; Zhou, C | 1 |
| Koutmos, M; Mendoza, J; Purchal, M; Yamada, K | 1 |
| Caggana, M; Cohen-Pfeffer, JL; Diaz, GA; Kirmse, BM; McGuire, PJ; Morrissey, MA; Salveson, BR; Sunny, S; Wasserstein, MP; Weisfeld-Adams, JD; Yu, C | 1 |
20 review(s) available for s-adenosylmethionine and vitamin b 12
| Article | Year |
|---|---|
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1976 |
Mechanisms for the biomethylation of metals and metalloids.
Topics: Alkylmercury Compounds; Arsenic; Carbazoles; Cell Membrane Permeability; Metals; Methylation; Methylmercury Compounds; Organometallic Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyrenes; S-Adenosylmethionine; Spectrometry, Fluorescence; Tetrahydrofolates; Vitamin B 12 | 1978 |
The biosynthesis of methionine.
Topics: Animals; Apoproteins; Bacteria; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Drug Stability; Enzyme Activation; Escherichia coli; Flavins; Homocysteine; Methionine; Methyltransferases; Molecular Weight; Oxidation-Reduction; Plants; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1973 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Binding site revealed of nature's most beautiful cofactor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Escherichia coli; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1994 |
Hypothesis on the pathogenesis of vacuolar myelopathy, dementia, and peripheral neuropathy in AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Cytokines; Demyelinating Diseases; Folic Acid; Glutathione; Humans; Macrophage Activation; Oligodendroglia; Peripheral Nervous System Diseases; S-Adenosylmethionine; Spinal Cord Diseases; Vacuoles; Vitamin B 12 | 1998 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
[Postoperative combined medullary sclerosis revealing Biermer's disease: toxic effect of nitrous oxide].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Abscess; Aged; Anemia, Pernicious; Anesthetics, Inhalation; Arthroplasty, Replacement, Hip; Atrophy; Autoantibodies; Autoimmune Diseases; Demyelinating Diseases; Female; Gastric Mucosa; Humans; Intestinal Absorption; Intrinsic Factor; Nitrous Oxide; Oxidation-Reduction; Paresthesia; Postoperative Complications; Proprioception; S-Adenosylmethionine; Sclerosis; Spinal Cord; Spinal Cord Diseases; Surgical Wound Infection; Vitamin B 12 | 2000 |
Nutritional regulation of homocysteine: effects of drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2001 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Radical-mediated enzymatic methylation: a tale of two SAMS.
Topics: Free Radicals; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2012 |
Radical use of Rossmann and TIM barrel architectures for controlling coenzyme B12 chemistry.
Topics: Bacteria; Catalysis; Catalytic Domain; Cobamides; Free Radicals; Humans; Intramolecular Transferases; Iron; Ligands; Methylmalonyl-CoA Mutase; S-Adenosylmethionine; Vitamin B 12 | 2012 |
Folate, vitamin B₁₂, and S-adenosylmethionine.
Topics: Clinical Trials as Topic; Dementia; Depression; Folic Acid; Humans; S-Adenosylmethionine; Vitamin B 12 | 2013 |
Neuroenhancement with vitamin B12-underestimated neurological significance.
Topics: Alzheimer Disease; Brain; Cognition; Homocysteine; Humans; Incidence; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2013 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
Therapeutic perspectives of epigenetically active nutrients.
Topics: Antineoplastic Agents; Coffee; Curcumin; Diet; Epigenesis, Genetic; Folic Acid; Food; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Metabolic Syndrome; Neoplasms; Neurodegenerative Diseases; Phytoestrogens; Polyphenols; S-Adenosylmethionine; Selenium; Trace Elements; Vitamin B 12; Vitamin B Complex; Vitamins | 2015 |
Vitamin B
Topics: Cobamides; Enzymes; Light; S-Adenosylmethionine; Vitamin B 12 | 2017 |
A Rich Man, Poor Man Story of S-Adenosylmethionine and Cobalamin Revisited.
Topics: Animals; Binding Sites; Coenzymes; Electrochemistry; Enzymes; Free Radicals; Humans; Models, Molecular; Molecular Structure; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Cobalamin-dependent radical S-adenosyl-l-methionine enzymes in natural product biosynthesis.
Topics: Adenine; Aminobutyrates; Biological Products; Enzymes; Fosfomycin; Gentamicins; Methylation; S-Adenosylmethionine; Shewanella; Thiostrepton; Vitamin B 12 | 2018 |
Computational Approaches: An Underutilized Tool in the Quest to Elucidate Radical SAM Dynamics.
Topics: Acetyltransferases; Density Functional Theory; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Quantum Theory; S-Adenosylmethionine; Vitamin B 12 | 2021 |
9 trial(s) available for s-adenosylmethionine and vitamin b 12
| Article | Year |
|---|---|
[Double-blind polycentric study of the action of S-adenosylmethionine in hepatic cirrhosis].
Topics: Aged; Blood Proteins; Clinical Trials as Topic; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Protein Biosynthesis; S-Adenosylmethionine; Vitamin B 12 | 1975 |
[Double-blind studies of the therapeutic action of S-Adenosylmethionine (SAMe) in oral administration, in liver cirrhosis and other chronic hepatitides].
Topics: Chronic Disease; Clinical Trials as Topic; Hepatitis; Humans; Liver Cirrhosis; Liver Function Tests; S-Adenosylmethionine; Vitamin B 12 | 1975 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study.
Topics: Aged; Arteriosclerosis; Carotid Arteries; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocytes; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Tunica Intima; Tunica Media; Vitamin B 12; Vitamin B 6 | 2003 |
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates; Ultrasonography; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin B 6 | 2005 |
Elevated serum S-adenosylhomocysteine in cobalamin-deficient elderly and response to treatment.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gas Chromatography-Mass Spectrometry; Humans; Kidney; Linear Models; Male; Middle Aged; Nutrition Assessment; S-Adenosylhomocysteine; S-Adenosylmethionine; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia.
Topics: Acetylcarnitine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Dementia; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Institutionalization; Learning; Male; Memory; Middle Aged; Reference Values; S-Adenosylmethionine; Vitamin B 12; Vitamin E; Vitamins; Young Adult | 2010 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
165 other study(ies) available for s-adenosylmethionine and vitamin b 12
| Article | Year |
|---|---|
The biosynthesis of vitamin B12.
Topics: Aminolevulinic Acid; Models, Chemical; Porphobilinogen; Propionibacterium; S-Adenosylmethionine; Stereoisomerism; Uroporphyrinogens; Vitamin B 12 | 1976 |
Stereochemical studies of enzymic C-methylations.
Topics: Enzymes; Magnetic Resonance Spectroscopy; Methionine; Methylation; S-Adenosylmethionine; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12 | 1977 |
N5-Methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity in chronic erythremic myelosis (Di Guglielmo syndrome).
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Apoenzymes; Bone Marrow; Homocysteine; Humans; Leukemia, Erythroblastic, Acute; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1977 |
De novo synthesis of methionine in normal and Brugia-infected Aedes aegypti.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aedes; Animals; Brugia; Cell-Free System; Female; Filarioidea; Homocysteine; Male; Methionine; Molecular Weight; S-Adenosylmethionine; Tetrahydrofolates; Tissue Extracts; Vitamin B 12 | 1979 |
Biomethylation of toxic elements in the environment.
Topics: Arsenic; Biotransformation; Chemical Phenomena; Chemistry; Iron; Lead; Mercury; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tetrahydrofolates; Tin; Vitamin B 12 | 1977 |
Studies on metabolic role of 5'-Methylthioadenosine in Ochromonas malhamensis and other microorganisms.
Topics: Adenosine; Cell Membrane Permeability; Eukaryota; Methionine; N-Glycosyl Hydrolases; Ribose; S-Adenosylmethionine; Vitamin B 12 | 1976 |
Rapid separation of cobyrinic acid and its biosynthetic precursors by ion-exchange paper chromatography.
Topics: Aminolevulinic Acid; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Propionibacterium; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1976 |
The relationships between vitamin B12 and folic acid and the effect of methionine on folate metabolism.
Topics: Animals; Biological Transport; Diet; Folic Acid; Formiminoglutamic Acid; Histidine; Liver; Male; Methionine; Perfusion; Rats; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis.
Topics: Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Magnetic Resonance Spectroscopy; Methyltransferases; Molecular Sequence Data; S-Adenosylmethionine; Salmonella typhimurium; Uroporphyrins; Vitamin B 12 | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Low thyroxine levels in female psychiatric inpatients with riboflavin deficiency: implications for folate-dependent methylation.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Hospitalization; Humans; Male; Mental Disorders; Middle Aged; Pyridoxine; Riboflavin; Riboflavin Deficiency; S-Adenosylmethionine; Thiamine; Thyroid Function Tests; Thyroxine; Vitamin B 12 | 1992 |
Effect of cobalamin derivatives on in vitro enzymatic DNA methylation: methylcobalamin can act as a methyl donor.
Topics: Animals; DNA; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spleen; Vitamin B 12 | 1991 |
Biosynthesis of vitamin B12: isolation of precorrin-6x, a metal-free precursor of the corrin macrocycle retaining five S-adenosylmethionine-derived peripheral methyl groups.
Topics: Magnetic Resonance Spectroscopy; Methylation; NADP; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1990 |
The nature of the defect in cobalamin G mutation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Cell Division; Cells, Cultured; Female; Fibroblasts; Humans; Infant; Male; Methionine; Mutation; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1989 |
Oxidation of 5-methyltetrahydrofolate in cobalamin-inactivated rats.
Topics: Animals; Formyltetrahydrofolates; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1989 |
Effects of nitrous oxide inactivation of vitamin B12 and of methionine on folate coenzyme metabolism in rat liver, kidney, brain, small intestine and bone marrow.
Topics: Animals; Bone Marrow; Brain; Folic Acid; Intestine, Small; Kidney; Liver; Male; Methionine; Nitrous Oxide; Organ Specificity; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1989 |
Cobalamin-dependent methionine synthase from Escherichia coli B: electron paramagnetic resonance spectra of the inactive form and the active methylated form of the enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electron Spin Resonance Spectroscopy; Escherichia coli; Methylation; Methyltransferases; Molecular Weight; Oxidation-Reduction; S-Adenosylmethionine; Vitamin B 12 | 1988 |
Perturbation of methionine metabolism in sheep with nitrous-oxide-induced inactivation of cobalamin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Brain; Formiminoglutamic Acid; Homocystine; Liver; Male; Methionine; Methylmalonyl-CoA Mutase; Methyltransferases; Myocardium; Nitrous Oxide; Orchiectomy; S-Adenosylmethionine; Sheep; Vitamin B 12 | 1986 |
Altered methionine metabolism in metastatic variants of a human melanoma cell line.
Topics: Cell Division; Culture Media; Homocysteine; Humans; Melanoma; Methionine; Neoplasm Metastasis; S-Adenosylmethionine; Tumor Cells, Cultured; Vitamin B 12 | 1989 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
Role of S-adenosylmethionine in DNA synthesis and haemopoiesis.
Topics: Bone Marrow; Deoxyuridine; DNA Replication; Hematopoiesis; Humans; Methionine; Nitrous Oxide; S-Adenosylmethionine; Thymidine; Vitamin B 12 | 1985 |
Study of inorganic arsenic methylation by rat liver in vitro: relevance for the interpretation of observations in man.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Coenzymes; Cytosol; Enzyme Inhibitors; Glutathione; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1985 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Urinary excretion of 5-methyltetrahydrofolate and liver S-adenosylmethionine levels of rats fed a vitamin B 12-deficient diet.
Topics: Animals; Bacteria; Biological Assay; Biological Transport; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Drug Stability; Ethionine; Folic Acid; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Vitamin B12-dependent methionine synthesis in Rhizobium meliloti.
Topics: Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Dithiothreitol; Flavin Mononucleotide; Homocysteine; Kinetics; Magnesium; Methionine; Methyltransferases; Oxidation-Reduction; Rhizobium; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1974 |
5-methyltetrahydrofolate homocysteine cobalamin methyltransferase in human bone marrow and its relationship to pernicious anemia.
Topics: Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Erythrocytes; Homocysteine; Humans; Kinetics; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Studies on the regulation of one-carbon metabolism. II. Repression-derepression of serine hydroxymethyltransferase by methionine in Escherichia coli 113-3.
Topics: Ammonium Sulfate; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Repression; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Methionine; Methyltransferases; Molecular Weight; Oxidoreductases; S-Adenosylmethionine; Serine; Tetrahydrofolate Dehydrogenase; Thymine Nucleotides; Transferases; Uracil Nucleotides; Vitamin B 12 | 1972 |
Regulation of the terminal reactions in methionine biosynthesis by vitamin B 12 and methionine.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Carbon Isotopes; Drug Antagonism; Enzyme Induction; Enzyme Repression; Escherichia coli; Genetics, Microbial; Kinetics; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Tetrahydrofolates; Transferases; Vitamin B 12 | 1972 |
Regulation of homocysteine biosynthesis in Salmonella typhimurium.
Topics: Acyltransferases; Bacteriological Techniques; Carbon Isotopes; Enzyme Repression; Feedback; Genetics, Microbial; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Methionine; Molecular Biology; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Spectrophotometry; Succinates; Tetrahydrofolates; Tritium; Vitamin B 12 | 1972 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
[Studies on vitamin B 12 -dependent reactions in Ascaris suum].
Topics: Animals; Ascaris; Cobamides; Coenzyme A; Female; Isomerases; Ligands; Malonates; Methylation; Methyltransferases; Ovary; RNA; RNA, Transfer; S-Adenosylmethionine; Vitamin B 12 | 1972 |
Stereochemistry of methyl group insertion in corrinoid biosynthesis. Determination of carbon isotope chirality by 13C nuclear magnetic resonance.
Topics: Carbon Isotopes; Magnetic Resonance Spectroscopy; Methylation; Porphyrins; Propionibacterium; S-Adenosylmethionine; Stereoisomerism; Vitamin B 12 | 1973 |
Biosynthesis of corrins. A cell-free system from Propionibacterium shermanii.
Topics: Cell-Free System; Porphyrins; Propionibacterium; S-Adenosylmethionine; Vitamin B 12 | 1973 |
Enzymes catalyzing the de novo synthesis of methyl groups in the brain and other tissues of the rat.
Topics: Aerobiosis; Alcohol Oxidoreductases; Animals; Brain; Carbon Radioisotopes; Dihydroxyphenylalanine; Female; Kidney; Liver; Male; Mercaptoethanol; Methionine; Methyltransferases; Rats; S-Adenosylmethionine; Serine; Sex Factors; Tetrahydrofolates; Transferases; Vitamin B 12; Vitamin K | 1973 |
Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa.
Topics: Animals; Body Weight; Brain; Dihydroxyphenylalanine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Male; Methionine; Organ Size; Organ Specificity; Rats; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1974 |
Isolation of a cobalamin containing 5-methyltetrahydrofolate-homocysteine transmethylase from mammalian kidney.
Topics: Ammonium Sulfate; Animals; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Kidney; Methods; Methyltransferases; Protamines; S-Adenosylmethionine; Spectrophotometry; Sulfuric Acids; Swine; Ultraviolet Rays; Vitamin B 12 | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
Methylation and mood.
Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency | 1984 |
Synergistic growth inhibiting effect of nitrous oxide and cycloleucine in experimental rat leukaemia.
Topics: Amino Acids; Animals; Cycloleucine; Deoxyuridine; Drug Synergism; Folic Acid; Leukemia, Experimental; Leukocyte Count; Liver; Male; Nitrous Oxide; Organ Size; Rats; Rats, Inbred BN; S-Adenosylmethionine; Spleen; Vitamin B 12 | 1984 |
Tissue S-adenosylmethionine levels in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced neuropathy.
Topics: Animals; Brain; Cerebellar Ataxia; Chiroptera; Diet; Folic Acid; Liver; Methionine; Nitrous Oxide; Paralysis; S-Adenosylmethionine; Vitamin B 12 | 1983 |
Effects of nitrous oxide-induced inactivation of cobalamin on methionine and S-adenosylmethionine metabolism in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Brain; Liver; Male; Methionine; Methyltransferases; Nitrous Oxide; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Vitamin B 12 | 1983 |
Chronic cobalamin inactivation impairs folate polyglutamate synthesis in the rat.
Topics: Adenosine; Animals; Deoxyadenosines; Folic Acid; Formyltetrahydrofolates; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Vitamin B 12; Vitamin B 12 Deficiency | 1983 |
[Cobalamins and tRNA methyltransferase activity in E. coli cells].
Topics: Escherichia coli; Kinetics; S-Adenosylmethionine; tRNA Methyltransferases; Vitamin B 12 | 1981 |
Separation of cobyrinic acid and its biosynthetic precursors by ion-exchange paper chromatography.
Topics: Aminolevulinic Acid; Chromatography, Ion Exchange; Chromatography, Paper; Levulinic Acids; Porphyrinogens; S-Adenosylmethionine; Uroporphyrinogens; Vitamin B 12 | 1980 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Protective effects of a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nitroprusside; Pregnancy; Rats; S-Adenosylmethionine; Vitamin B 12 | 1993 |
Nitrous oxide inactivation of cobalamin-dependent methionine synthase from Escherichia coli: characterization of the damage to the enzyme and prosthetic group.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Electrochemistry; Escherichia coli; Homocysteine; Methionine; Molecular Sequence Data; Nitrous Oxide; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1994 |
Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans.
Topics: Carbon Isotopes; Cobamides; Corrinoids; Escherichia coli; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Methyltransferases; Molecular Structure; Plasmids; Pseudomonas; Restriction Mapping; S-Adenosylmethionine; Vitamin B 12 | 1993 |
Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Escherichia coli; Homocysteine; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1993 |
Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group.
Topics: Bacterial Proteins; Base Sequence; DNA, Single-Stranded; Methylation; Methyltransferases; Molecular Sequence Data; Oxidation-Reduction; Oxygenases; Pseudomonas; S-Adenosylmethionine; Uroporphyrins; Vitamin B 12 | 1993 |
Pathogenesis of cobalamin neuropathy: deficiency of nervous system S-adenosylmethionine?
Topics: Child, Preschool; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
A novel antiviral strategy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; DNA, Viral; HIV; HIV Infections; HIV Seropositivity; Humans; Methylation; Proviruses; S-Adenosylmethionine; Tetrahydrofolates; Virus Replication; Vitamin B 12 | 1993 |
[Participation of methylcobalamin in DNA methylation in vitro].
Topics: Animals; Cattle; DNA; DNA Modification Methylases; DNA, Bacterial; Liver; Methylation; Micrococcus luteus; Rats; S-Adenosylmethionine; Vitamin B 12 | 1995 |
Mono- and dimethylation of arsenic in rat liver cytosol in vitro.
Topics: Animals; Arsenates; Arsenic; Arsenicals; Arsenites; Cacodylic Acid; Edetic Acid; Egtazic Acid; Glutathione; Liver; Male; Mercuric Chloride; Methylation; Methyltransferases; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Selenite; Vitamin B 12 | 1996 |
The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Protein Conformation; S-Adenosylmethionine; Sequence Homology, Amino Acid; Vitamin B 12 | 1996 |
Interaction of Escherichia coli cobalamin-dependent methionine synthase and its physiological partner flavodoxin: binding of flavodoxin leads to axial ligand dissociation from the cobalamin cofactor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding, Competitive; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferredoxin-NADP Reductase; Flavodoxin; Flavoproteins; Hydrogen-Ion Concentration; Oxidation-Reduction; S-Adenosylmethionine; Spectrophotometry; Thiocyanates; Vitamin B 12 | 1997 |
Protective effects of methylcobalamin, a vitamin B12 analog, against glutamate-induced neurotoxicity in retinal cell culture.
Topics: Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Glutamic Acid; Neurons; Nitroprusside; Rats; Retina; S-Adenosylmethionine; Sulfhydryl Reagents; Trypan Blue; Vitamin B 12 | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Purification and some properties of cobalamin-dependent methionine synthase from rat liver.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Kinetics; Liver; Molecular Weight; Rats; S-Adenosylmethionine; Vitamin B 12 | 1997 |
Effect of mutations in the transmethylase and dehydrogenase/chelatase domains of sirohaem synthase (CysG) on sirohaem and cobalamin biosynthesis.
Topics: Amino Acid Sequence; Consensus Sequence; Escherichia coli; Genetic Complementation Test; Heme; Methyltransferases; Molecular Sequence Data; Point Mutation; S-Adenosylmethionine; Salmonella typhimurium; Sequence Alignment; Sequence Homology, Amino Acid; Vitamin B 12 | 1998 |
Methionine synthase exists in two distinct conformations that differ in reactivity toward methyltetrahydrofolate, adenosylmethionine, and flavodoxin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkyl and Aryl Transferases; Binding, Competitive; Flavodoxin; Glycine; Histidine; Hydrolysis; Methylation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1998 |
Cobalamin (vitamin B12) biosynthesis--cloning, expression and crystallisation of the Bacillus megaterium S-adenosyl-L-methionine-dependent cobalt-precorrin-4 transmethylase CbiF.
Topics: Bacillus megaterium; Base Sequence; Cloning, Molecular; Cobalt; Crystallization; Dimerization; DNA Primers; Escherichia coli Proteins; Gene Expression; Genes, Bacterial; Methyltransferases; Molecular Weight; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine; Vitamin B 12 | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
The mechanism of adenosylmethionine-dependent activation of methionine synthase: a rapid kinetic analysis of intermediates in reductive methylation of Cob(II)alamin enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Aspartic Acid; Cobalt; Electron Transport; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1998 |
Transmethylation reactions and autoradiographic distribution of vitamin B12: effects of clioquinol treatment in mice.
Topics: Animals; Anti-Infective Agents, Local; Autoradiography; Brain; Chloroform; Clioquinol; Cobalt Radioisotopes; Kidney; Liver; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Scintillation Counting; Solubility; Tissue Distribution; Vitamin B 12; Water | 1998 |
Changes in uptake of vitamin B(12) and trace metals in brains of mice treated with clioquinol.
Topics: Amebicides; Animals; Brain; Clioquinol; Male; Metals; Mice; Mice, Inbred Strains; Optic Nerve Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine; Trace Elements; Vitamin B 12 | 2000 |
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats.
Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Reverse methionine biosynthesis from S-adenosylmethionine in eukaryotic cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Deoxyadenosines; Fungal Proteins; Gene Expression Regulation; Homocysteine S-Methyltransferase; Membrane Proteins; Methionine; Molecular Sequence Data; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Thionucleosides; Vitamin B 12; Vitamin U; Yeasts | 2000 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Mapping the interactions between flavodoxin and its physiological partners flavodoxin reductase and cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Flavodoxin; Magnetic Resonance Spectroscopy; Models, Molecular; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Protein Binding; Protein Conformation; S-Adenosylmethionine; Vitamin B 12 | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Vitamin B 12 | 2001 |
Domain alternation switches B(12)-dependent methionine synthase to the activation conformation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Models, Molecular; Movement; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; S-Adenosylmethionine; Vitamin B 12 | 2002 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations.
Topics: Aged; Aged, 80 and over; Body Constitution; Cardiovascular Diseases; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Regression Analysis; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2003 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
ADENOSYLMETHIONINE ELEVATION IN LEUKEMIC WHITE BLOOD CELLS.
Topics: Antimetabolites; Biochemical Phenomena; Biochemistry; Drug Therapy; Humans; Leukemia; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Lymphocytes; Methionine; Nucleosides; S-Adenosylmethionine; Vitamin B 12 | 1965 |
Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.
Topics: Arabidopsis; Blotting, Western; Chloroplasts; Cloning, Molecular; Cytosol; Diffusion; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Green Fluorescent Proteins; Homocysteine; Immunoblotting; Kinetics; Luminescent Proteins; Methionine; Mitochondria; Models, Biological; Molecular Sequence Data; Phylogeny; Pisum sativum; Plastids; Protein Isoforms; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Crystal structure and solution characterization of the activation domain of human methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Crystallization; Crystallography, X-Ray; Dimerization; Ferredoxin-NADP Reductase; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Alignment; Vitamin B 12 | 2007 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Antiparkinson Agents; Carbon; Catechol O-Methyltransferase Inhibitors; Catechols; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Nitriles; Parkinson Disease; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Time Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.
Topics: Aquaporins; Brain; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Muscular Dystrophy, Duchenne; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Enzyme Activation; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Temperature; Thermotoga maritima; Vitamin B 12 | 2007 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Spectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Circular Dichroism; Cobalt; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Enzyme Activation; Models, Molecular; Protein Structure, Tertiary; S-Adenosylmethionine; Tyrosine; Vitamin B 12 | 2008 |
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.
Topics: Autistic Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Glutathione; Humans; Leucovorin; Male; Methylation; Nutritional Status; Oxidation-Reduction; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Methyladeninylcobamide functions as the cofactor of methionine synthase in a Cyanobacterium, Spirulina platensis NIES-39.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Bacteria; Cyanobacteria; Inorganic Chemicals; Molecular Sequence Data; Organic Chemicals; Protein Structure, Tertiary; S-Adenosylmethionine; Vitamin B 12 | 2010 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2011 |
Radical SAM activation of the B12-independent glycerol dehydratase results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine.
Topics: Catalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Glycine; Hydro-Lyases; Methionine; Oxidation-Reduction; S-Adenosylmethionine; Thionucleosides; Vitamin B 12 | 2011 |
Thymidylate synthase gene polymorphisms and markers of DNA methylation capacity.
Topics: Adult; Case-Control Studies; Cholesterol; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genetic Association Studies; Genetic Markers; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; S-Adenosylhomocysteine; S-Adenosylmethionine; Serum Albumin; Thymidylate Synthase; Vitamin B 12 | 2011 |
In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea.
Topics: Bacterial Proteins; Catalysis; DNA Methylation; Methyltransferases; Naphthoquinones; Phosphinic Acids; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Streptomycetaceae; Vitamin B 12 | 2011 |
Relationships among biomarkers of one-carbon metabolism.
Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult | 2012 |
[Hepatoprotectors in addictive medicine].
Topics: Chemical and Drug Induced Liver Injury; Ethanol; Humans; Liver; Protective Agents; Psychotropic Drugs; S-Adenosylmethionine; Substance-Related Disorders; Vitamin B 12; Vitamin B Complex | 2012 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12 | 2012 |
Phospholipase D activation mediates cobalamin-induced downregulation of Multidrug Resistance-1 gene and increase in sensitivity to vinblastine in HepG2 cells.
Topics: 1-Butanol; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bezafibrate; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Activators; Gene Expression; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Oleic Acid; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phospholipase D; S-Adenosylmethionine; Vinblastine; Vitamin B 12 | 2013 |
Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes.
Topics: Cloning, Molecular; Dithionite; Dithiothreitol; Escherichia coli; Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Thiostrepton; Tryptophan; Vitamin B 12 | 2012 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
[State of thiol exchange in patients with psoriasis and its possible correction].
Topics: Ascorbic Acid; Calcium Gluconate; Erythrocytes; Female; Folic Acid; Glutathione; Glutathione Peroxidase; Humans; Infusions, Intravenous; Male; Psoriasis; S-Adenosylmethionine; Severity of Illness Index; Succinates; Sulfhydryl Compounds; Vitamin B 12 | 2013 |
The mechanisms of radical SAM/cobalamin methylations: an evolving working hypothesis.
Topics: Anti-Bacterial Agents; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiostrepton; Tryptophan; Vitamin B 12 | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
Topics: Biocatalysis; Free Radicals; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2013 |
Crystal structure of putative CbiT from Methanocaldococcus jannaschii: an intermediate enzyme activity in cobalamin (vitamin B12) biosynthesis.
Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Methanocaldococcus; Methyltransferases; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Alignment; Uroporphyrins; Vitamin B 12 | 2013 |
Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits.
Topics: Animals; Betaproteobacteria; Caenorhabditis elegans; Diet; Escherichia coli; Gene Expression Regulation; Metabolic Networks and Pathways; Methionine; Molecular Sequence Data; Propionates; S-Adenosylmethionine; Transcriptome; Vitamin B 12 | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring.
Topics: Animals; Brain; Female; Folic Acid; Homocysteine; Lactation; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B Deficiency | 2014 |
Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Catalysis; Cephalosporins; Chromatography, Liquid; Cloning, Molecular; DNA Methylation; Drug Design; Escherichia coli; Fermentation; Methylation; Penicillins; S-Adenosylmethionine; Streptomyces; Tandem Mass Spectrometry; Thienamycins; Vitamin B 12 | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
Spectroscopic and Electrochemical Characterization of the Iron-Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase.
Topics: Coenzymes; Electrochemistry; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Methyltransferases; S-Adenosylmethionine; Spectroscopy, Mossbauer; Vitamin B 12 | 2016 |
Neuregulin 1 Promotes Glutathione-Dependent Neuronal Cobalamin Metabolism by Stimulating Cysteine Uptake.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Androstadienes; Cell Line, Tumor; Cysteine; Excitatory Amino Acid Transporter 3; Glutathione; Humans; Low Density Lipoprotein Receptor-Related Protein-2; Methylation; Neuregulin-1; Neurons; Real-Time Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Vitamin B 12; Wortmannin | 2016 |
Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
Topics: Acetyltransferases; Biocatalysis; Electron Spin Resonance Spectroscopy; Enzymes; Iron-Sulfur Proteins; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; S-Adenosylmethionine; Vitamin B 12 | 2016 |
Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta.
Topics: Adult; Albumins; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Apolipoprotein E4; Female; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Reference Values; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 2016 |
The B
Topics: Biocatalysis; Free Radicals; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Molecular Conformation; Proteins; S-Adenosylmethionine; Vitamin B 12 | 2016 |
Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme.
Topics: Alkylation; Anti-Bacterial Agents; Asparagine; Biocatalysis; Free Radicals; Methyl Ethers; Methyltransferases; Molecular Structure; Nitro Compounds; S-Adenosylmethionine; Vitamin B 12 | 2017 |
A B
Topics: Adenine; Adenosine Monophosphate; Bacillus megaterium; Bacterial Proteins; Biocatalysis; Coenzymes; Crystallography, X-Ray; Deoxyadenine Nucleotides; Genes, Bacterial; Models, Molecular; Multigene Family; Protein Conformation; S-Adenosylmethionine; Vitamin B 12 | 2017 |
Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis.
Topics: Biosynthetic Pathways; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Streptomyces; Substrate Specificity; Vitamin B 12 | 2017 |
Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical
Topics: Bacterial Proteins; Biocatalysis; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Kinetics; Methylation; Methyltransferases; Molecular Structure; Recombinant Fusion Proteins; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry; Staphylococcus; Substrate Specificity; Thiostrepton; Tryptophan; Vitamin B 12 | 2017 |
TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.
Topics: Bacterial Proteins; Biocatalysis; Coenzymes; Cysteine; Escherichia coli; Iron-Sulfur Proteins; Methylation; Methyltransferases; Protein Binding; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; Tryptophan; Vitamin B 12 | 2017 |
Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.
Topics: Biosynthetic Pathways; Catalytic Domain; Gentamicins; Methylation; Methyltransferases; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2017 |
Enhanced Solubilization of Class B Radical S-Adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli.
Topics: Escherichia coli; Methyltransferases; S-Adenosylmethionine; Solubility; Vitamin B 12 | 2018 |
Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-adenosyl-l-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Liquid; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Stereospecific Radical-Mediated B
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Free Radicals; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Topics: Animals; Biological Transport; Brain; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cell Nucleus; ELAV-Like Protein 1; Endoplasmic Reticulum Stress; Exportin 1 Protein; Humans; Karyopherins; Metabolic Diseases; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; Receptors, Cytoplasmic and Nuclear; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Sirtuin 1; Vitamin B 12 | 2018 |
Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase.
Topics: Bacterial Proteins; Cytidine Monophosphate; Escherichia coli; Fosfomycin; Methylation; Methyltransferases; Models, Chemical; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2018 |
Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B
Topics: Anisoles; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Enzyme Assays; Esters; Free Radicals; Methylation; Methyltransferases; Myxococcales; Nitro Compounds; Recombinant Proteins; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.
Topics: Animals; Basidiomycota; Diet, High-Fat; Fructose; Fungal Polysaccharides; Hypoglycemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Microbiota; Obesity; Phosphatidylcholines; S-Adenosylmethionine; Sucrose; Vitamin B 12 | 2018 |
An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12.
Topics: Anaerobiosis; Bacterial Proteins; Benzimidazoles; Biosynthetic Pathways; Desulfuromonas; Electron Spin Resonance Spectroscopy; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Binding studies of a putative C. pseudotuberculosis target protein from Vitamin B
Topics: Adenine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Corynebacterium pseudotuberculosis; Kinetics; Ligands; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Secondary; S-Adenosylmethionine; Spectrometry, Fluorescence; Structural Homology, Protein; Suramin; Vitamin B 12 | 2019 |
Methanogenesis marker protein 10 (Mmp10) from
Topics: Archaeal Proteins; Biocatalysis; Chromatography, High Pressure Liquid; Kinetics; Matrix Metalloproteinase 10; Methanosarcina; Methylation; Peptides; Recombinant Proteins; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Vitamin B 12 | 2019 |
Understanding the role of electron donors in the reaction catalyzed by Tsrm, a cobalamin-dependent radical S-adenosylmethionine methylase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Dithiothreitol; Escherichia coli; Hydroxocobalamin; Iron-Sulfur Proteins; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2019 |
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2019 |
Surprise! A hidden B
Topics: Biocatalysis; Matrix Metalloproteinase 10; Methylation; Oxidoreductases; Peptides; S-Adenosylmethionine; Substrate Specificity; Vitamin B 12 | 2019 |
Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Topics: Arginine; Catalysis; Coenzymes; Iron-Sulfur Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomycetaceae; Thiostrepton; Tryptophan; Vitamin B 12; X-Ray Diffraction | 2021 |
Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women.
Topics: Adolescent; Adult; Cesarean Section; Cross-Sectional Studies; Depression, Postpartum; Diet; Female; Homocysteine; Humans; India; Methylmalonic Acid; Pregnancy; Pregnancy, Unplanned; Risk Factors; S-Adenosylmethionine; Serotonin; Social Class; Tetrahydrofolates; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Overall Retention of Methyl Stereochemistry during B
Topics: Bacterial Proteins; Cytidine Monophosphate; Fosfomycin; Methylation; Methyltransferases; Organophosphonates; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Vitamin B 12 | 2021 |
The B
Topics: Bacterial Proteins; Clostridium butyricum; Deoxyadenosines; Hydro-Lyases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
One-carbon metabolism during the menstrual cycle and pregnancy.
Topics: Carbon; Estradiol; Female; Folic Acid; Homocysteine; Humans; Menstrual Cycle; Pregnancy; S-Adenosylmethionine; Vitamin B 12 | 2021 |
Crystallographic snapshots of a B
Topics: Archaeal Proteins; Electron Spin Resonance Spectroscopy; Methanosarcina; Methylation; Protein Conformation; Protein Processing, Post-Translational; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Structure of a B
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Biocatalysis; Carbapenems; Coenzymes; Crystallography, X-Ray; Kinetics; Methylation; Methyltransferases; Models, Molecular; Protein Binding; Protein Domains; S-Adenosylmethionine; Streptomyces; Thienamycins; Vitamin B 12 | 2022 |
Mechanistic investigation of B12-independent glycerol dehydratase and its activating enzyme GD-AE.
Topics: Biocatalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Hydro-Lyases; Molecular Structure; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Exploring the Biosynthetic Potential of TsrM, a B
Topics: Methylation; Methyltransferases; S-Adenosylmethionine; Tryptophan; Vitamin B 12 | 2022 |
The Atypical Cobalamin-Dependent
Topics: Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
A Cobalamin-Dependent Radical SAM Enzyme Catalyzes the Unique C
Topics: Glutamine; Methane; Methylation; Methyltransferases; Oxidoreductases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in carbapenem β-lactam antibiotic biosynthesis.
Topics: Anti-Bacterial Agents; Carbapenems; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Structural characterization of cobalamin-dependent radical S-adenosylmethionine methylases.
Topics: Crystallography, X-Ray; Escherichia coli; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Characterization of the cobalamin-dependent radical S-adenosyl-l-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis.
Topics: Fosfomycin; Methyltransferases; S-Adenosylmethionine; Streptomyces; Vitamin B 12 | 2022 |
Studies of GenK and OxsB, two B
Topics: Biological Products; Biosynthetic Pathways; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Purification and structural elucidation of a cobalamin-dependent radical SAM enzyme.
Topics: Biosynthetic Pathways; Iron-Sulfur Proteins; S-Adenosylmethionine; Vitamin B 12 | 2022 |
As3MT-mediated SAM consumption, which inhibits the methylation of histones and LINE1, is involved in arsenic-induced male reproductive damage.
Topics: 5-Methylcytosine; Animals; Arsenic; Arsenic Poisoning; DNA; DNA Methylation; Folic Acid; Histones; Male; Methyltransferases; Mice; S-Adenosylmethionine; Semen; Vitamin B 12 | 2022 |
Two Radical SAM Enzymes Are Necessary and Sufficient for the In Vitro Production of the Oxetane Nucleoside Antiviral Agent Albucidin.
Topics: Antiviral Agents; Biological Products; Carbon; Ethers, Cyclic; Hydrogen; Nucleosides; Phosphates; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins | 2022 |
Mechanism of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine; Vitamin B 12 | 2022 |
The impact of pre-pregnancy folic acid intake on placental DNA methylation in a fortified cohort.
Topics: Carbon; DNA Methylation; Female; Folic Acid; Genotype; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Placenta; Pregnancy; S-Adenosylmethionine; Vitamin B 12 | 2023 |
Vitamin D, Folic Acid and Vitamin B
Topics: Animals; Folic Acid; Memory Disorders; Mice; Mice, Inbred C57BL; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex; Vitamin D; Vitamin D Deficiency | 2022 |
Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Folic Acid; Methionine; S-Adenosylmethionine; Vitamin B 12 | 2023 |
Newborn screening and early biochemical follow-up in combined methylmalonic aciduria and homocystinuria, cblC type, and utility of methionine as a secondary screening analyte.
Topics: Algorithms; Carnitine; Demography; False Positive Reactions; Female; Follow-Up Studies; Genetic Association Studies; Homocystinuria; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Methionine; Methylmalonic Acid; Neonatal Screening; New York; Propionates; Referral and Consultation; Vitamin B 12 | 2010 |