Page last updated: 2024-08-23

s-adenosylmethionine and mercaptopurine

s-adenosylmethionine has been researched along with mercaptopurine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's7 (58.33)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Szumlanski, CL; Van Loon, JA; Weinshilboum, RM1
Keith, RA; Otterness, DM; Weinshilboum, RM1
De Abreu, R; Lambooy, L; Stet, E; Van den Heuvel, L; Vogels-Mentink, T1
Blom, HJ; Bökkerink, JP; De Abreu, RA; de Graaf-Hess, AC; Lambooy, LH; Stet, EH; Trijbels, FJ; van Raay-Selten, B; Vogels-Mentink, TM1
Aarbakke, J; Klemetsdal, B; Straume, B; Wist, E1
Evans, WE; Fessing, MY; Krynetskaia, NF; Krynetski, EY; Loennechen, T; Tai, HL; Yates, CR1
Blom, HJ; Bökkerink, JP; De Abreu, RA; Keuzenkamp-Jansen, CW; Trijbels, JM1
Aarbakke, J; Giverhaug, T; Lysaa, RA; Wold, HL1
Cara, C; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Menor, C; Román, ID1
Karas Kuzelicki, N; Milek, M; Mlinaric-Rascan, I; Smid, A1
Deshayes, S; Echaabi, AK; Illamola, SM; Loriot, MA; Mazeron, C; Pallet, N1
Atkinson, N; Crews, KR; Li, L; Molinelli, AR1

Other Studies

12 other study(ies) available for s-adenosylmethionine and mercaptopurine

ArticleYear
Human kidney thiopurine methyltransferase. Photoaffinity labeling with S-adenosyl-L-methionine.
    Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4

    Topics: Adenosine; Affinity Labels; Autoradiography; Chromatography, Ion Exchange; Gallic Acid; Humans; Isoenzymes; Kidney; Mercaptopurine; Methyltransferases; Photolysis; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine

1992
Thiopurine methyltransferase: mouse kidney and liver assay conditions, biochemical properties and strain variation.
    Biochemical pharmacology, 1985, Nov-01, Volume: 34, Issue:21

    Topics: Animals; Chromatography, Thin Layer; Female; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Male; Mercaptopurine; Methyltransferases; Mice; Mice, Inbred Strains; S-Adenosylmethionine; Sex Factors; Species Specificity; Time Factors

1985
Thiopurine induced disturbance of DNA methylation in human malignant cells.
    Advances in enzyme regulation, 1995, Volume: 35

    Topics: Antimetabolites, Antineoplastic; Cell Death; DNA, Neoplasm; Humans; Mercaptopurine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Thioinosine; Thionucleotides; Tumor Cells, Cultured

1995
Decrease in S-adenosylmethionine synthesis by 6-mercaptopurine and methylmercaptopurine ribonucleoside in Molt F4 human malignant lymphoblasts.
    The Biochemical journal, 1994, Nov-15, Volume: 304 ( Pt 1)

    Topics: Adenosine Triphosphate; Cell Division; Cell Survival; Humans; Leukemia-Lymphoma, Adult T-Cell; Mercaptopurine; S-Adenosylmethionine; Thionucleosides; Tumor Cells, Cultured

1994
Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adult; Erythrocytes; Ethnicity; Female; Humans; Male; Mercaptopurine; Methyltransferases; Middle Aged; Norway; Polymorphism, Genetic; Regression Analysis; S-Adenosylmethionine; Sex Characteristics

1993
Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.
    American journal of human genetics, 1996, Volume: 58, Issue:4

    Topics: Amino Acid Sequence; Base Sequence; Child, Preschool; Cloning, Molecular; DNA, Complementary; DNA, Neoplasm; Enzyme Stability; Erythrocytes; Gene Frequency; Humans; Kinetics; Male; Mercaptopurine; Methylation; Methyltransferases; Molecular Sequence Data; Point Mutation; Polymorphism, Restriction Fragment Length; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; RNA, Messenger; S-Adenosylmethionine; White People; Yeasts

1996
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
    Biochemical pharmacology, 1996, May-03, Volume: 51, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine

1996
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide.
    European journal of clinical pharmacology, 1996, Volume: 49, Issue:5

    Topics: Bendroflumethiazide; Diuretics; Erythrocytes; Furosemide; Humans; In Vitro Techniques; Lethal Dose 50; Mercaptopurine; Methylation; Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Trichlormethiazide

1996
Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: comparison with the radiochemical method.
    Therapeutic drug monitoring, 2001, Volume: 23, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azathioprine; Chromatography, High Pressure Liquid; Drug Monitoring; Erythrocytes; Humans; Linear Models; Mercaptopurine; Methyltransferases; Radiochemistry; S-Adenosylmethionine; Thioguanine

2001
S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts.
    Biochemical pharmacology, 2009, Jun-15, Volume: 77, Issue:12

    Topics: Cell Line, Tumor; Drug Antagonism; Humans; Lymphocytes; Mercaptopurine; Methyltransferases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; S-Adenosylmethionine

2009
Development and validation of a UPLC-UV method for the quantification of thiopurine methyltransferase enzyme activity in human erythrocytes.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Apr-15, Volume: 1113

    Topics: Chromatography, High Pressure Liquid; Drug Monitoring; Enzyme Assays; Erythrocytes; Humans; Limit of Detection; Linear Models; Mercaptopurine; Methyltransferases; Reproducibility of Results; S-Adenosylmethionine

2019
Determination of Thiopurine S-Methyltransferase (TPMT) Activity in Human Erythrocytes by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
    Methods in molecular biology (Clifton, N.J.), 2024, Volume: 2737

    Topics: Chromatography, Liquid; Erythrocytes; Genotype; Humans; Mercaptopurine; Methyltransferases; S-Adenosylmethionine; Tandem Mass Spectrometry

2024