s-adenosylmethionine has been researched along with glycine in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (22.09) | 18.7374 |
| 1990's | 13 (15.12) | 18.2507 |
| 2000's | 18 (20.93) | 29.6817 |
| 2010's | 26 (30.23) | 24.3611 |
| 2020's | 10 (11.63) | 2.80 |
| Authors | Studies |
|---|---|
| Frisell, WR; Lewis, KF; Nemeth, E; Randolph, VM | 1 |
| Walker, JB | 1 |
| Eloranta, TO | 1 |
| Kerr, SJ; Trewyn, RW | 1 |
| Case, GL | 1 |
| Kim, S; Paik, WK | 1 |
| Fujioka, M; Konishi, K | 1 |
| Fujioka, M; Gomi, T; Takata, Y | 1 |
| Fell, D; Selhub, J | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Lindenbaum, A | 1 |
| Kerr, SJ | 1 |
| Heady, JE; Kerr, SJ | 2 |
| Balish, E | 1 |
| Meedel, TH; Pizer, LI | 1 |
| Stadtman, TC | 1 |
| Pillinger, DJ | 1 |
| Stephens, GC; Taylor, D; Van Pilsum, JF | 2 |
| Demain, AL; White, RF | 1 |
| Fujioka, M; Ishiguro, Y; Ogawa, H | 1 |
| Kikuchi, S; Nishitani, H; Okumura, K; Taguchi, H | 1 |
| Granzin, J; Labahn, J; Saenger, W; Schildkraut, I; Schluckebier, G | 1 |
| Frey, M; Knappe, J; Rothe, M; Wagner, AF | 1 |
| Alakuijala, L; Eloranta, TO; Korhonen, VP; Regina, M; Smith, TK | 1 |
| Fujioka, M; Gomi, T; Hamahata, A; Takata, Y | 1 |
| Ogawa, H | 1 |
| Huang, S; Jarrett, JT; Matthews, RG | 1 |
| Fujioka, M; Gomi, T; Ogawa, H; Takusagawa, F | 1 |
| Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
| Ilas, J; Mühl, A; Stöckler-Ipsiroglu, S | 1 |
| Feng, L; Kirsch, JF | 1 |
| Fujioka, M; Gomi, T; Huang, Y; Komoto, J; Konishi, K; Ogawa, H; Takata, Y; Takusagawa, F | 1 |
| Fontecave, M; Mulliez, E; Padovani, D; Thomas, F; Trautwein, AX | 1 |
| Chiang, EP; Herbig, K; Hills, J; Lee, LR; Shane, B; Stover, PJ | 1 |
| Fengsrud, M; Møller, MT; Samari, HR; Seglen, PO; Strømhaug, PE; øStvold, AC | 1 |
| Choi, KH; Kim, SK; Kim, YC | 1 |
| Appling, DR; Chan, SY | 1 |
| Buckel, W; Golding, BT | 1 |
| Blacquiere, KD; Coykendall, CE; Hay, CM; Honsey, LE; Miller, RR; Striegnitz, TR | 1 |
| Fukada, S; Morita, T; Setoue, M; Sugiyama, K | 1 |
| Miller, RR; Walcher, BN | 1 |
| Mori, M; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Benjdia, A; Berteau, O; Leprince, J; Sandström, C; Vaudry, H | 1 |
| Benjdia, A; Berteau, O; Johnson, MK; Leprince, J; Subramanian, S; Vaudry, H | 1 |
| Ding, JG; Fu, RQ; Hong, L; Sun, QF; Wang, JR; Wang, XF; Wu, JG; Xu, DZ; Xu, XJ; Yang, JX | 1 |
| Demick, JM; Lanzilotta, WN | 1 |
| Brosnan, JT; Brosnan, ME; Brown, C; da Silva, RP; Deminice, R; Furey, GN; Jacobs, RL; Jordao, AA; Kelly, KB; King-Jones, K; Lamarre, SG; McCarter, SA | 1 |
| Asara, JM; Cantley, LC; Daley, GQ; Locasale, JW; Lyssiotis, CA; Onder, T; Ratanasirintrawoot, S; Shyh-Chang, N; Teo, RY; Unternaehrer, JJ; Zhang, J; Zheng, Y; Zhu, H | 1 |
| Chakrabarti, M; Dangott, LJ; Kamat, SS; Raushel, FM; Williams, HJ | 1 |
| Booker, SJ; Drennan, CL; Goldman, PJ; Grove, TL; McLaughlin, MI; Sites, LA | 1 |
| Brosnan, JT; Brosnan, ME; Clow, K; da Silva, RP | 1 |
| da Cunha, SF; de Freitas, EC; Deminice, R; Franco, GS; Jordao, AA; Rosa, FT | 1 |
| French, SW; Kharbanda, KK; Orlicky, DJ; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Bertolo, RF; Brunton, JA; Furlong, KR; McBreairty, LE; Robinson, JL | 1 |
| Collet, JP; Dunbar, M; Edgar, V; Elango, R; Jaggumantri, S; Mignone, C; Newlove, T; Sargent, M; Stockler-Ipsiroglu, S; van Karnebeek, CD | 1 |
| Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Feng, D; French, SW; Ganesan, M; Kharbanda, KK; Maillacheruvu, PF; Orlicky, DJ; Osna, NA; Tuma, DJ | 1 |
| Bardeesy, N; Boukhali, M; Chen, T; Dyson, NJ; Gu, H; Haas, W; Hammerman, PS; Hayes, DN; Hayward, MC; Karnik, R; Kottakis, F; Li, YY; Liesa, M; Meissner, A; Nagle, JM; Nicolay, BN; Roumane, A; Shirihai, OS; Wong, KK | 1 |
| Fukaya, M; Hosoya, KI; Sakai, K; Tachikawa, M; Terasaki, T; Watanabe, M | 1 |
| Aydin, HI | 1 |
| Brosnan, JT; Brosnan, ME; Clow, KA; MacMillan, L; Randell, EW; Tingley, G; Young, SK | 1 |
| Chouhan, BPS; Gade, M; Laurino, P; Maimaiti, S | 1 |
| Kazimierczuk, K; Nawrocka, EK; Perlinska, AP; Setny, P; Stasiulewicz, A; Sulkowska, JI | 1 |
| Breaker, RR | 1 |
| Li, M; Ling, H; Liu, C; Lu, L; Shen, Y; Sun, S; Wang, J; Xu, N; Yang, C; Zhang, J; Zhang, W; Zhang, X; Zhao, L | 1 |
| Fogle, HM; Krupenko, NI; Krupenko, SA; McCormac, JP; Molina, S; Rushing, BR; Sharma, J; Sumner, S; You, M | 1 |
| de Hoffmann, E; Libert, R; Nassogne, MC; Schanck, A; Stroobant, V; Thillaye, M; Van Hoof, F; Vincent, MF | 1 |
| Andresen, BS; Angel, L; Bennetts, B; Carpenter, K; Waddell, L; Wilcken, B; Wiley, V | 1 |
| Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF | 1 |
| Bodamer, OA; Heinze, G; Holub, M; Mühl, A; Ratschmann, R; Sperl, W; Strnadová, KA; Tuschl, K | 1 |
| Bennett, MJ | 1 |
| Deigner, HP; Enot, D; Keller, M; Koal, T; Saugstad, OD; Scholl-Bürgi, S; Solberg, R | 1 |
| Hata, I; Shigematsu, Y; Tajima, G | 1 |
| Adamski, J; Gieger, C; Illig, T; Kronenberg, F; Krumsiek, J; Meitinger, T; Mittelstrass, K; Peters, A; Polonikov, A; Prehn, C; Ried, JS; Roemisch-Margl, W; Suhre, K; Theis, FJ; Wang-Sattler, R; Weidinger, S; Wichmann, HE; Yu, Z | 1 |
| Fong, BM; Leung, KS; Tam, S | 1 |
| Akiba, K; Aoyama, Y; Fukao, T; Goto, M; Hasegawa, Y; Hashimoto, T; Hori, T; Kuwayama, N; Morita, M; Moriyama, Y; Murayama, K; Ohtake, A; Shigematsu, Y; Usuda, N; Venkatesan, R; Wierenga, R | 1 |
| Bo, R; Hasegawa, Y; Ishige, N; Kobayashi, H; Nakamura, M; Takahashi, T; Yamada, K; Yamaguchi, S | 1 |
| Alarcón Riquelme, ME; Beretta, L; Borrás-Linares, I; Fernández-Ochoa, Á; Gemperline, D; Quirantes-Piné, R; Segura-Carretero, A | 1 |
| Arning, E; Ashcraft, P; Bottiglieri, T; Brown, M; Gibson, KM; Jansen, E; Kirby, T; Rinaldo, P; Roullet, JB; Salomons, GS; Turgeon, C; Walters, DC | 1 |
| Beger, RD; Cao, Z; Nakamura, N; Pence, LM | 1 |
| Brumarová, R; Dobešová, D; Friedecký, D; Jahn, P; Kopecká, A; Tóthová, K | 1 |
| De Grassi, A; Giangregorio, N; Incampo, G; Indiveri, C; Pierri, CL; Tonazzi, A; Tragni, V | 1 |
| Canizales-Quinteros, S; Flores, YN; Ibarra-González, I; León-Reyes, G; Palacios-González, B; Rivera-Paredez, B; Salmerón, J; Vela-Amieva, M; Velázquez-Cruz, R | 1 |
| Adibi, H; Arjmand, B; Dehghanbanadaki, H; Farzadfar, F; Ghodssi-Ghassemabadi, R; Hosseinkhani, S; Larijani, B; Mohammadi Fateh, S; Najjar, N; Razi, F; Rezaei, N; Tayanloo-Beik, A; Yoosefi, M | 1 |
8 review(s) available for s-adenosylmethionine and glycine
| Article | Year |
|---|---|
Creatine: biosynthesis, regulation, and function.
Topics: Amidinotransferases; Animals; Arginine; Creatine; Diet, Vegetarian; Enzyme Repression; Glycine; Guanidines; Humans; Liver; Male; Methyltransferases; Phosphocreatine; S-Adenosylmethionine; Substrate Specificity; Transferases | 1979 |
Protein methylation: chemical, enzymological, and biological significance.
Topics: Amino Acids; Animals; Arginine; Cations, Divalent; Chloramphenicol; DNA; Glycine; Humans; Kinetics; Liver; Lysine; Methionine; Methyltransferases; Molecular Weight; Organ Specificity; Proteins; Rats; S-Adenosylmethionine; Species Specificity; Tetrahymena; Thymus Gland; Time Factors; tRNA Methyltransferases | 1975 |
Modulation of tRNA methyltransferase activity by competing enzyme systems.
Topics: Animals; Brain; Carcinoma, Hepatocellular; Catechol O-Methyltransferase; Estrogens; Female; Fetus; Glycine; Kinetics; Liver; Liver Neoplasms; Methyltransferases; Rabbits; Rats; S-Adenosylmethionine; tRNA Methyltransferases; Uterus | 1974 |
Selenium biochemistry.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Clostridium; Electron Transport; Escherichia coli; Glycine; Metalloproteins; Methionine; Nucleotidyltransferases; Plants; Radioisotopes; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenium; Sulfates | 1974 |
[Glycine methyltransferase: structure, function and a variety of ligand- bindings].
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Folate Receptors, GPI-Anchored; Glycine; Glycine N-Methyltransferase; Humans; Ligands; Methyltransferases; Molecular Sequence Data; Receptors, Cell Surface; S-Adenosylmethionine; Sarcosine | 1996 |
Structure, function and physiological role of glycine N-methyltransferase.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Catalysis; Crystallography, X-Ray; Escherichia coli; Gene Expression Regulation, Enzymologic; Glycine; Glycine N-Methyltransferase; Humans; Liver; Methyltransferases; Mice; Molecular Sequence Data; Pteroylpolyglutamic Acids; Rabbits; Rats; S-Adenosylmethionine; Sequence Homology, Amino Acid; Species Specificity | 1998 |
Radical enzymes in anaerobes.
Topics: Amino Acids; Bacteria, Anaerobic; Cobamides; Flavins; Free Radicals; Glycine; Hydro-Lyases; Methane; Pyruvate Synthase; S-Adenosylmethionine | 2006 |
Assays of fatty acid beta-oxidation activity.
Topics: Acids; Biological Transport, Active; Carnitine; Fatty Acids; Glycine; Humans; Lipid Metabolism; Mitochondria; Models, Biological; Oxidation-Reduction | 2007 |
4 trial(s) available for s-adenosylmethionine and glycine
| Article | Year |
|---|---|
Efficacy and safety of intravenous stronger neo-minophagen C and S-adenosyl-L-methionine in treatment of pregnant woman with chronic hepatitis B: a pilot study.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Cysteine; Demography; Drug Combinations; Drug Therapy, Combination; Embryonic Development; Female; Follow-Up Studies; Glycine; Glycyrrhetinic Acid; Health; Hepatitis B, Chronic; Humans; Infant, Newborn; Injections, Intravenous; Liver Function Tests; Pilot Projects; Pregnancy; S-Adenosylmethionine; Treatment Outcome | 2010 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Association of plasma acylcarnitines and amino acids with hypertension: A nationwide metabolomics study.
Topics: Amino Acids; Autonomic Nervous System Diseases; Glycine; Humans; Hypertension; Iran; Metabolomics | 2023 |
74 other study(ies) available for s-adenosylmethionine and glycine
| Article | Year |
|---|---|
Oxidation of one-carbon compounds to formate and carbon dioxide in rat liver mitochondria.
Topics: Animals; Carbon Dioxide; Diphosphates; Edetic Acid; Formates; Formyltetrahydrofolates; Glycine; Magnesium; Mitochondria, Liver; Phosphates; Rats; S-Adenosylmethionine; Sarcosine; Serine | 1978 |
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines.
Topics: Age Factors; Animals; Brain; Glycine; Homocysteine; Hydrolases; Kidney; Liver; Methionine; Methionine Adenosyltransferase; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 1977 |
The enzymatic synthesis of S-adenosyl-L-[2(n)-3H]homocysteine.
Topics: Animals; Glycine; Homocysteine; Hydrolases; Liver; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
Evidence for S-adenosylmethionine independent catabolism of methionine in the rat.
Topics: Animals; Carbon Dioxide; Cysteine; Formaldehyde; Formates; Glycine; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Serine | 1976 |
Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide.
Topics: Adenosine; Animals; Cysteine; Enzyme Activation; Enzyme Reactivators; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glycine; Guanidinoacetate N-Methyltransferase; Iodoacetates; Iodoacetic Acid; Kinetics; Liver; Mercaptoethanol; Methyltransferases; Oxidation-Reduction; Rats; Recombinant Proteins; S-Adenosylmethionine; Spectrum Analysis; Sulfhydryl Compounds | 1991 |
Recombinant rat guanidinoacetate methyltransferase: structure and function of the NH2-terminal region as deduced by limited proteolysis.
Topics: Amino Acid Sequence; Animals; Enzyme Activation; Glycine; Guanidinoacetate N-Methyltransferase; Hydrolysis; Liver; Methyltransferases; Molecular Sequence Data; Molecular Weight; Pancreatic Elastase; Rats; Recombinant Proteins; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity; Trypsin | 1991 |
Disruption of thymidylate synthesis and glycine-serine interconversion by L-methionine and L-homocystine in Raji cells.
Topics: Amino Acids; Burkitt Lymphoma; Glycine; Glycine Hydroxymethyltransferase; Homocystine; Humans; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1990 |
In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate.
Topics: Adenosine; Animals; Betaine; Carbon Dioxide; Deoxyadenosines; Formyltetrahydrofolates; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thionucleosides; Time Factors | 1988 |
A survey of naturally occurring chelating ligands.
Topics: Animals; Binding Sites; Chelating Agents; Copper; Dihydroxyphenylalanine; Edetic Acid; Electron Transport; Enzyme Activation; Epinephrine; Flavin-Adenine Dinucleotide; Glycine; Histamine; Histidine; Hydrogen-Ion Concentration; Ligands; Macromolecular Substances; Methyltransferases; Norepinephrine; Oxalates; Polymers; Rats; S-Adenosylmethionine | 1973 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |
Methionine biosynthesis and S-adenosylmethionine degradation during an induced morphogenesis of Candida albicans.
Topics: Candida albicans; Carbon Isotopes; Cell-Free System; Culture Media; Glycine; Homocysteine; Methionine; Methyltransferases; Morphogenesis; S-Adenosylmethionine | 1973 |
Regulation of one-carbon biosynthesis and utilization in Escherichia coli.
Topics: Adenine; Alcohol Oxidoreductases; Carbon Radioisotopes; Cell-Free System; Culture Media; Enzyme Repression; Escherichia coli; Formaldehyde; Glycine; Ligases; Methionine; Mutation; Nucleosides; Oxidoreductases; S-Adenosylmethionine; Serine; Spermidine; Tetrahydrofolates; Transferases | 1974 |
Enzymatic methylation of glycine using a cell free supernatant from rat liver.
Topics: Animals; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Glycine; In Vitro Techniques; Liver; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Sarcosine | 1972 |
Purification and characterization of glycine N-methyltransferase.
Topics: Acetates; Amino Acids; Ammonium Sulfate; Animals; Carbon Isotopes; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Glycine; Hexoses; Hydroxyapatites; Kinetics; Liver; Macromolecular Substances; Methyltransferases; Molecular Weight; Neuraminic Acids; Rabbits; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Ultracentrifugation | 1973 |
Distribution of creatine, guanidinoacetate and the enzymes for their biosynthesis in the animal kingdom. Implications for phylogeny.
Topics: Acetates; Animals; Annelida; Arginine; Biological Evolution; Canavanine; Carbon Isotopes; Chordata, Nonvertebrate; Creatine; Echinodermata; Glycine; Guanidines; Invertebrates; Methyltransferases; Organ Specificity; S-Adenosylmethionine; Species Specificity; Transferases; Vertebrates | 1972 |
Distribution of creatine, guanidinoacetate and enzymes for their biosynthesis in the animal kingdom. Implications for phylogeny.
Topics: Acetates; Amidines; Animals; Anura; Arginine; Biological Evolution; Carbon Isotopes; Chickens; Chromatography, Paper; Creatine; Fishes; Fresh Water; Glycine; Guanidines; Humans; Male; Methyltransferases; Rats; S-Adenosylmethionine; Seawater; Sharks; Transferases; Turtles; Vertebrates | 1972 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
Guanidoacetate methyltransferase from rat liver: purification, properties, and evidence for the involvement of sulfhydryl groups for activity.
Topics: Amino Acids; Animals; Glutathione; Glycine; Guanidinoacetate N-Methyltransferase; Kinetics; Liver; Methyltransferases; Molecular Weight; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1983 |
Finding of a homarine-synthesizing enzyme in turban shell and some properties of the enzyme.
Topics: Adenosine; Alkaloids; Animals; Cations, Divalent; Enzyme Inhibitors; Glycine; Invertebrates; Methyltransferases; Picolinic Acids; S-Adenosylhomocysteine; S-Adenosylmethionine; Snails; Species Specificity | 1995 |
A model for DNA binding and enzyme action derived from crystallographic studies of the TaqI N6-adenine-methyltransferase.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Glycine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1995 |
Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site.
Topics: Acetyltransferases; Amino Acid Sequence; Binding Sites; Deoxyadenosines; Escherichia coli; Free Radicals; Glycine; Hydrogen; Molecular Sequence Data; Peptides; S-Adenosylmethionine; Substrate Specificity | 1994 |
Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway.
Topics: Amino Acids; Animals; Body Weight; Diet; Feeding Behavior; Glycine; Kidney; Liver; Male; Methionine; Muscles; Rats; Rats, Wistar; S-Adenosylmethionine; Serine | 1993 |
Probing the S-adenosylmethionine-binding site of rat guanidinoacetate methyltransferase. Effect of site-directed mutagenesis of residues that are conserved across mammalian non-nucleic acid methyltransferases.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Circular Dichroism; Conserved Sequence; Glycine; Guanidinoacetate N-Methyltransferase; Kinetics; Methyltransferases; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Rats; S-Adenosylmethionine | 1996 |
Methionine synthase exists in two distinct conformations that differ in reactivity toward methyltetrahydrofolate, adenosylmethionine, and flavodoxin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkyl and Aryl Transferases; Binding, Competitive; Flavodoxin; Glycine; Histidine; Hydrolysis; Methylation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Guanidinoacetate methyltransferase (GAMT) deficiency: non-invasive enzymatic diagnosis of a newly recognized inborn error of metabolism.
Topics: Amniotic Fluid; Cells, Cultured; Chromatography, High Pressure Liquid; Creatine; Female; Fetal Diseases; Fibroblasts; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Lymphocytes; Male; Metabolism, Inborn Errors; Methyltransferases; Pregnancy; Prenatal Diagnosis; S-Adenosylmethionine; Skin | 2000 |
L-Vinylglycine is an alternative substrate as well as a mechanism-based inhibitor of 1-aminocyclopropane-1-carboxylate synthase.
Topics: Ammonia; Butyrates; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Glycine; Imines; Kinetics; Lyases; Pichia; Recombinant Proteins; S-Adenosylmethionine; Schiff Bases; Spectrophotometry; Substrate Specificity | 2000 |
Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Consensus Sequence; Crystallography, X-Ray; Glycine; Glycine N-Methyltransferase; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 2000 |
Activation of class III ribonucleotide reductase from E. coli. The electron transfer from the iron-sulfur center to S-adenosylmethionine.
Topics: Anaerobiosis; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Activation; Escherichia coli; Free Radicals; Glycine; Iron-Sulfur Proteins; Kinetics; Oxidation-Reduction; Ribonucleotide Reductases; S-Adenosylmethionine; Spectroscopy, Mossbauer | 2001 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Topics: Animals; Cell Line; Cytoplasm; Deoxyribonucleotides; DNA; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Methylation; S-Adenosylmethionine; Tetrahydrofolates; Thymidine Monophosphate | 2002 |
Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes.
Topics: Aminoimidazole Carboxamide; Animals; Bucladesine; Cell-Free System; Enzyme Inhibitors; Flavanones; Flavonoids; Glycine; Glycine N-Methyltransferase; Hepatocytes; Methyltransferases; Okadaic Acid; Peptide Fragments; Phosphorylation; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.
Topics: Alkynes; Amino Acids; Animals; Betaine; Biological Transport; Cystathionine; Cystathionine gamma-Lyase; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glycine; Liver; Methionine; Mice; Mice, Inbred ICR; Oxygenases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2003 |
Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.
Topics: Cell Division; Cysteine; Formates; Gene Deletion; Gene Expression Regulation, Fungal; Genotype; Glycine; Homocysteine; Microscopy, Fluorescence; Models, Biological; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfur; Time Factors; Vacuoles | 2003 |
Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos.
Topics: Animals; Apoptosis; Brain; Brain Chemistry; Caspase 3; Caspases; Chick Embryo; Fatty Acids; Glycine; Homocysteine; Lipid Peroxides; Liver; Membranes; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Dietary eritadenine suppresses guanidinoacetic Acid-induced hyperhomocysteinemia in rats.
Topics: Adenine; Animals; Diet; Glycine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains.
Topics: Animals; Apoptosis; Brain; Caspase 3; Central Nervous System Depressants; Chick Embryo; Chickens; Down-Regulation; Embryonic Development; Enzyme Activation; Ethanol; Glycine; Homocysteine; S-Adenosylhomocysteine; S-Adenosylmethionine; Up-Regulation | 2008 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme.
Topics: Alanine; Anaerobiosis; Catalysis; Clostridium perfringens; Deoxyadenosines; Glycine; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfatases | 2009 |
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?
Topics: Alanine; Anaerobiosis; Binding Sites; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Eukaryota; Glycine; Iron-Sulfur Proteins; Oxidation-Reduction; S-Adenosylmethionine; Serine; Substrate Specificity; Sulfatases | 2010 |
Radical SAM activation of the B12-independent glycerol dehydratase results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine.
Topics: Catalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Glycine; Hydro-Lyases; Methionine; Oxidation-Reduction; S-Adenosylmethionine; Thionucleosides; Vitamin B 12 | 2011 |
Creatine supplementation prevents the accumulation of fat in the livers of rats fed a high-fat diet.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Amidinotransferases; Animals; Carnitine O-Palmitoyltransferase; Creatine; Dietary Fats; Dietary Supplements; Fatty Liver; Gene Expression Regulation; Glycine; Kidney; Lipid Metabolism; Lipid Peroxidation; Liver; Male; PPAR alpha; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylmethionine | 2011 |
Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Culture Media; Embryonic Stem Cells; Epigenesis, Genetic; Fibroblasts; Glycine; Histones; Induced Pluripotent Stem Cells; Metabolic Networks and Pathways; Methylation; Mice; Pluripotent Stem Cells; S-Adenosylmethionine; Threonine; Transcription Factors | 2013 |
The catalytic mechanism for aerobic formation of methane by bacteria.
Topics: Aerobiosis; Archaea; Bacteria; Bacterial Proteins; Biocatalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Glycine; Hydrogen; Lyases; Mass Spectrometry; Methane; Methionine; Mutant Proteins; Pentosephosphates; S-Adenosylmethionine | 2013 |
X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.
Topics: Anaerobiosis; Bacterial Proteins; Clostridium perfringens; Free Radicals; Glycine; Oxidation-Reduction; Protein Processing, Post-Translational; Protein Structure, Tertiary; S-Adenosylmethionine | 2013 |
Synthesis of guanidinoacetate and creatine from amino acids by rat pancreas.
Topics: Amidinotransferases; Amino Acids; Animals; Creatine; Creatinine; Diet; Dietary Supplements; Glycine; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Male; Pancreas; Phosphocreatine; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Increased methylation demand exacerbates ethanol-induced liver injury.
Topics: Alcohol Drinking; Amidinotransferases; Animals; Chemical and Drug Induced Liver Injury; Diet; Ethanol; Fatty Liver, Alcoholic; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2014 |
Guanidinoacetate is more effective than creatine at enhancing tissue creatine stores while consequently limiting methionine availability in Yucatan miniature pigs.
Topics: Animals; Body Weight; Creatine; Diet; Dietary Supplements; Glycine; Liver; Methionine; Methylation; Muscles; S-Adenosylmethionine; Swine; Swine, Miniature; Tissue Distribution | 2015 |
Treatment of Creatine Transporter (SLC6A8) Deficiency With Oral S-Adenosyl Methionine as Adjunct to L-arginine, Glycine, and Creatine Supplements.
Topics: Administration, Oral; Arginine; Basal Ganglia; Brain Diseases, Metabolic, Inborn; Central Nervous System Agents; Child; Creatine; Drug Therapy, Combination; Follow-Up Studies; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Medication Adherence; Mental Retardation, X-Linked; Plasma Membrane Neurotransmitter Transport Proteins; S-Adenosylmethionine; Treatment Outcome | 2015 |
Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury.
Topics: Alanine Transaminase; Amidinotransferases; Animals; Aspartate Aminotransferases; Body Weight; Calcium-Binding Proteins; Cholesterol; Dietary Supplements; DNA-Binding Proteins; Ethanol; Fatty Acids; Fatty Liver; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Inflammation; Insulin; Liver; Liver Diseases; Male; Nerve Tissue Proteins; Nucleobindins; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2016 |
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Silencing; Genes, Tumor Suppressor; Glycine; Glycolysis; Humans; Mice; Pancreatic Ducts; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Retroelements; S-Adenosylmethionine; Serine; TOR Serine-Threonine Kinases; Transaminases | 2016 |
Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain.
Topics: Animals; Brain; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Methyltransferases; Mice, Inbred C57BL; Neurons; Phosphocreatine; S-Adenosylmethionine | 2018 |
Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.
Topics: Adolescent; Arginine; Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Creatine; Glycine; Humans; Male; Mental Retardation, X-Linked; Nerve Tissue Proteins; Plasma Membrane Neurotransmitter Transport Proteins; S-Adenosylmethionine; Siblings | 2018 |
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Rossmann-Fold Methyltransferases: Taking a "β-Turn" around Their Cofactor, S-Adenosylmethionine.
Topics: Alanine; Binding Sites; Coenzymes; Computer Simulation; Flavin-Adenine Dinucleotide; Glycine; Methylation; Methyltransferases; Mutagenesis; NAD; Protein Conformation; Protein Folding; S-Adenosylmethionine | 2019 |
Restriction of S-adenosylmethionine conformational freedom by knotted protein binding sites.
Topics: Adenine; Amino Acid Motifs; Binding Sites; Computational Biology; Computer Simulation; Databases, Protein; Glycine; Magnetic Resonance Spectroscopy; Methionine Adenosyltransferase; Molecular Dynamics Simulation; Principal Component Analysis; Protein Binding; Protein Domains; Protein Folding; S-Adenosylmethionine; Solvents; Temperature; tRNA Methyltransferases; Water | 2020 |
The Biochemical Landscape of Riboswitch Ligands.
Topics: Aptamers, Nucleotide; Binding Sites; Glutamine; Glycine; Ligands; Lysine; Riboswitch; RNA, Bacterial; S-Adenosylmethionine | 2022 |
Glycine increased ferroptosis via SAM-mediated GPX4 promoter methylation in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Ferroptosis; Fibroblasts; Glycine; Methylation; Mice; S-Adenosylmethionine; Synovial Membrane; Synoviocytes | 2022 |
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions.
Topics: Aldehyde Dehydrogenase 1 Family; Folic Acid; Glycine; Humans; Metabolomics; Methylation; Neoplasms; Retinal Dehydrogenase; S-Adenosylmethionine | 2022 |
Identification of new medium-chain acylcarnitines present in urine of a patient with medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; Child, Preschool; Female; Glucuronates; Glycine; Humans | 1999 |
Medium-chain acyl-CoA dehydrogenase deficiency: genotype-biochemical phenotype correlations.
Topics: Acyl-CoA Dehydrogenase; Carnitine; DNA Mutational Analysis; Fibroblasts; Genetic Testing; Genetic Variation; Genotype; Glycine; Homozygote; Humans; Infant, Newborn; Mass Spectrometry; Phenotype; Statistics as Topic | 2006 |
Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.
Topics: Animals; Animals, Newborn; Anions; Brain; Cardiolipins; Carnitine; Carnitine O-Acetyltransferase; Glutamates; Glutamic Acid; Glycine; Hypoxia; Hypoxia-Ischemia, Brain; Immunohistochemistry; Lipid Metabolism; Mass Spectrometry; Microscopy, Fluorescence; Mitochondria; Phospholipids; Rats; Rats, Wistar; Superoxides; Time Factors; Vitamin B Complex | 2006 |
Influence of hematocrit and localisation of punch in dried blood spots on levels of amino acids and acylcarnitines measured by tandem mass spectrometry.
Topics: Amino Acids; Blood Specimen Collection; Blood Stains; Carnitine; Glycine; Hematocrit; Humans; Sensitivity and Specificity; Tandem Mass Spectrometry | 2006 |
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs.
Topics: Animals; Animals, Newborn; Asphyxia; Blood Proteins; Carnitine; Female; Glycine; Hydrogen-Ion Concentration; Hypoxia; Lactates; Male; Metabolomics; Oxygen; Resuscitation; Swine | 2010 |
Useful second-tier tests in expanded newborn screening of isovaleric acidemia and methylmalonic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Blood Specimen Collection; Carnitine; Case-Control Studies; Chromatography, Liquid; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Japan; Lactic Acid; Metabolism, Inborn Errors; Methylmalonic Acid; Neonatal Screening; Pilot Projects; Predictive Value of Tests; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry | 2010 |
Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Carnitine; Female; Genetic Markers; Genome-Wide Association Study; Glycine; Humans; Lipids; Male; Metabolome; Middle Aged; Polymorphism, Single Nucleotide; Sex Characteristics | 2011 |
Quantification of acylglycines in human urine by HPLC electrospray ionization-tandem mass spectrometry and the establishment of pediatric reference interval in local Chinese.
Topics: 1-Butanol; Acylation; Adolescent; Asian People; Calibration; Carnitine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deuterium; Female; Glycine; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Reference Values; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
The first case in Asia of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (HSD10 disease) with atypical presentation.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acetyltransferase; Base Sequence; Carnitine; Child; Diagnosis, Differential; DNA Mutational Analysis; Dyskinesias; Fibroblasts; Glycine; Humans; Hydroxybutyrates; Immunoblotting; Lipid Metabolism, Inborn Errors; Male; Mental Retardation, X-Linked; Mitochondria; Models, Molecular; Point Mutation; Protein Structure, Tertiary | 2014 |
Elevation of pivaloylcarnitine by sivelestat sodium in two children.
Topics: Amino Acid Metabolism, Inborn Errors; Cardiomyopathies; Carnitine; Child, Preschool; Chromatography, Liquid; Female; Glycine; Humans; Hyperammonemia; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Muscular Diseases; Neonatal Screening; Serine Proteinase Inhibitors; Sulfonamides; Tandem Mass Spectrometry | 2015 |
Urinary and plasma metabolite differences detected by HPLC-ESI-QTOF-MS in systemic sclerosis patients.
Topics: Acylation; Adult; Aged; Arachidonic Acids; Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Endocannabinoids; Female; Glycerides; Glycine; Humans; Male; Metabolomics; Middle Aged; Predictive Value of Tests; Prognosis; Reproducibility of Results; Scleroderma, Systemic; Spectrometry, Mass, Electrospray Ionization; Urinalysis | 2019 |
Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Brain; Carnitine; Creatine; Creatinine; Developmental Disabilities; gamma-Aminobutyric Acid; Glycine; Humans; Male; Metabolomics; Succinate-Semialdehyde Dehydrogenase | 2020 |
Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones.
Topics: Amino Acids; Animals; Biomarkers; Carnitine; Estradiol; Glycerophospholipids; Glycine; Gonadal Steroid Hormones; Humans; Inflammation; Lipids; Male; Metabolomics; Plasma; Prostatic Neoplasms; Prostatitis; Rats; Rats, Sprague-Dawley; Sphingomyelins | 2020 |
Dynamics of acylcarnitines, hypoglycin A, méthylènecyclopropylglycine and their metabolites in a Kladruber stallion with atypical myopathy.
Topics: Acyl-CoA Dehydrogenases; Animals; Carnitine; Creatine Kinase; Cyclopropanes; Fatty Acids; Glycine; Horse Diseases; Horses; Hypoglycins; Male; Muscular Diseases | 2022 |
Proline/Glycine residues of the PG-levels guide conformational changes along the transport cycle in the mitochondrial carnitine/acylcarnitine carrier (SLC25A20).
Topics: Alanine; Carnitine; Carnitine Acyltransferases; Glycine; Proline | 2022 |
Targeted Metabolomics Revealed a Sex-Dependent Signature for Metabolic Syndrome in the Mexican Population.
Topics: Carnitine; Citrulline; Cohort Studies; Female; Glycine; Humans; Male; Metabolic Syndrome; Metabolomics | 2022 |