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s-adenosylmethionine and eflornithine

s-adenosylmethionine has been researched along with eflornithine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's6 (23.08)18.2507
2000's2 (7.69)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brasitus, TA; Dudeja, PK; Halline, AG1
Claverie, N; Mamont, PS1
Clark, RS; McGovern, KA; Pegg, AE1
Kramer, DL; Pera, PJ; Porter, CW; Sufrin, JR1
Heby, O; Kanje, M; Mamont, PS; Oredsson, SM; Wagner, J1
Coward, JK; Pegg, AE; Secrist, JA; Talekar, RR1
Haegele, KD; Romijn, JC; Schechter, PJ; Sjoerdsma, A; Splinter, TA1
Eloranta, TO; Hyvönen, T; Pajula, RL; Smith, TK1
Osborne, HB; Papazafiri, P1
Bacchi, CJ; Yarlett, N2
Pegg, AE1
Danzin, C; Mamont, P; Wagner, J1
Bennett, RA; Pegg, AE; Pösö, H; Shuttleworth, K1
McCann, PP; Pegg, AE1
Eloranta, TO; Hyvönen, T; Keinänen, TA; Khomutov, AR; Khomutov, RM1
Ask, A; Frostesjö, L; Heby, O; Holm, I; Persson, L; Rehnholm, A1
McGarrity, TJ; Peiffer, LP1
Bacchi, CJ; Ciminelli, M; Garofalo, J; Goldberg, B; McCann, PP; Rattendi, D; Yarlett, N1
Bestor, TH; Frostesjö, L; Grahn, B; Heby, O; Holm, I; Page, AW1
Diegelman, P; Kee, K; Kisiel, N; Kramer, DL; Merali, S; Porter, CW; Powell, CT; Vujcic, S1
Fraser, AV; Wallace, HM1
Gilbert, D; Gu, X; Higham, DJ; Reid, D1
Chen, Q; Gross, SS; Kopelovich, L; Lipkin, SM; Witherspoon, M1
Bottiglieri, T; Casero, RA; Dunworth, M; Gambello, MJ; Kapfhamer, D; Kinchen, JM; McKenna, J; Murray-Stewart, T; Wasek, B1
Fukui, T; Rikiyama, T; Soda, K; Takao, K1

Reviews

3 review(s) available for s-adenosylmethionine and eflornithine

ArticleYear
Polyamine metabolism and function.
    The American journal of physiology, 1982, Volume: 243, Issue:5

    Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Eflornithine; Humans; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine

1982
Effects of antagonists of polyamine metabolism on African trypanosomes.
    Acta tropica, 1993, Volume: 54, Issue:3-4

    Topics: Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Eflornithine; Methylation; Polyamines; S-Adenosylmethionine; Trypanosoma; Trypanosomiasis, African

1993
Inhibitors of polyamine metabolism: review article.
    Amino acids, 2004, Volume: 26, Issue:4

    Topics: Animals; Disease; Eflornithine; Enzyme Inhibitors; Humans; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; S-Adenosylmethionine

2004

Other Studies

23 other study(ies) available for s-adenosylmethionine and eflornithine

ArticleYear
Differential stimulation of S-adenosylmethionine decarboxylase by difluoromethylornithine in the rat colon and small intestine.
    The Biochemical journal, 1989, Apr-15, Volume: 259, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Colon; Eflornithine; Intestinal Mucosa; Intestine, Small; Kinetics; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; S-Adenosylmethionine; Stimulation, Chemical

1989
Comparative antitumor properties in rodents of irreversible inhibitors of L-ornithine decarboxylase, used as such or as prodrugs.
    Cancer research, 1989, Aug-15, Volume: 49, Issue:16

    Topics: Administration, Oral; Alkynes; Animals; Diamines; Eflornithine; Injections, Intraperitoneal; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred DBA; Ornithine Decarboxylase Inhibitors; Prodrugs; S-Adenosylmethionine; Time Factors; Tumor Cells, Cultured

1989
Effect of 1,3,6-triaminohexane and 1,4,7-triaminoheptane on growth and polyamine metabolism in SV-3T3 cells treated with 2-difluoromethylornithine.
    Journal of cellular physiology, 1986, Volume: 127, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Eflornithine; Fibroblasts; Heptanes; Hexanes; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Simian virus 40; Spermidine

1986
Comparison of the biological effects of four irreversible inhibitors of ornithine decarboxylase in two murine lymphocytic leukemia cell lines.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Alkynes; Animals; Biological Transport; Cell Cycle; Cell Survival; Diamines; Eflornithine; Leukemia L1210; Leukemia L5178; Leukemia, Lymphoid; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine

1986
Polyamine depletion increases cellular ribonucleotide levels.
    Molecular and cellular biochemistry, 1986, Volume: 70, Issue:1

    Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography, High Pressure Liquid; Eflornithine; Mice; Ornithine; Putrescine; Rats; S-Adenosylmethionine; Spermine

1986
Effects of certain 5'-substituted adenosines on polyamine synthesis: selective inhibitors of spermine synthase.
    Biochemistry, 1986, Jul-15, Volume: 25, Issue:14

    Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cells, Cultured; Eflornithine; Escherichia coli; Kinetics; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine Synthase; Spermine Synthase; Structure-Activity Relationship; Transferases

1986
Decarboxylated-S-adenosylmethionine excretion: a biochemical marker of ornithine decarboxylase inhibition by alpha-difluoromethylornithine.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Aged; Creatinine; Eflornithine; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Ornithine Decarboxylase Inhibitors; Polyamines; S-Adenosylmethionine

1987
Effect of dietary methionine, arginine and ornithine on the metabolism and accumulation of polyamines, S-adenosylmethionine and macromolecules in rat liver and skeletal muscle.
    Annals of nutrition & metabolism, 1987, Volume: 31, Issue:3

    Topics: Amino Acids; Animals; Arginine; Body Weight; Diet; Eflornithine; Liver; Macromolecular Substances; Methionine; Muscles; Ornithine; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1987
Effect of alpha-difluoromethylornithine on DNA methylation in murine erythroleukaemic cells. Relationship to stimulation of induced differentiation.
    The Biochemical journal, 1987, Mar-01, Volume: 242, Issue:2

    Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; DNA; Eflornithine; Leukemia, Erythroblastic, Acute; Methylation; Mice; S-Adenosylmethionine; Stimulation, Chemical

1987
Effect of DL-alpha-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis grown in a semi-defined medium.
    Molecular and biochemical parasitology, 1988, Volume: 31, Issue:1

    Topics: Adenosine; Animals; Cadaverine; Chromatography, High Pressure Liquid; Culture Media; Eflornithine; Ornithine Decarboxylase; Polarography; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trichomonas vaginalis

1988
The role of polyamine depletion and accumulation of decarboxylated S-adenosylmethionine in the inhibition of growth of SV-3T3 cells treated with alpha-difluoromethylornithine.
    The Biochemical journal, 1984, Nov-15, Volume: 224, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Diamines; Eflornithine; Fibroblasts; Mice; Mice, Inbred Strains; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine

1984
Reversed-phase ion-pair liquid chromatographic procedure for the simultaneous analysis of S-adenosylmethionine, its metabolites and the natural polyamines.
    Journal of chromatography, 1982, Feb-12, Volume: 227, Issue:2

    Topics: Animals; Cells, Cultured; Chromatography, Liquid; Eflornithine; Liver; Liver Neoplasms, Experimental; Male; Ornithine; Polyamines; Prostate; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors

1982
Effect of inhibition of polyamine synthesis on the content of decarboxylated S-adenosylmethionine.
    The Biochemical journal, 1982, Feb-15, Volume: 202, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cells, Cultured; Eflornithine; Fibroblasts; Liver; Liver Regeneration; Male; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1982
Aminooxy analogues of spermidine evidence the divergent roles of the charged amino nitrogens in the cellular physiology of spermidine.
    Life sciences, 1995, Volume: 56, Issue:5

    Topics: Animals; Biogenic Polyamines; Biological Transport; Cell Division; Cells, Cultured; Cricetinae; Eflornithine; Embryo, Mammalian; Kidney; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Structure-Activity Relationship

1995
Development of resistance to hydroxyurea during treatment of human myelogenous leukemia K562 cells with alpha-difluoromethylornithine as a result of coamplification of genes for ornithine decarboxylase and ribonucleotide reductase R2 subunit.
    Cancer research, 1993, Nov-01, Volume: 53, Issue:21

    Topics: Animals; Blotting, Northern; Blotting, Southern; Cricetinae; Cricetulus; DNA Probes; Drug Resistance; Eflornithine; Electron Spin Resonance Spectroscopy; Gene Amplification; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Macromolecular Substances; Ornithine Decarboxylase; Polyamines; Ribonucleotide Reductases; RNA, Messenger; S-Adenosylmethionine; Tumor Cells, Cultured

1993
Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Dimethylhydrazines; Drug Interactions; Eflornithine; Liver; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Sprague-Dawley; Reference Values; S-Adenosylmethionine; Selenium; Spermidine; Spermine

1993
Resistance to DL-alpha-difluoromethylornithine by clinical isolates of Trypanosoma brucei rhodesiense. Role of S-adenosylmethionine.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Animals; Drug Resistance, Microbial; Eflornithine; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Trypanosoma brucei rhodesiense; Trypanosomiasis

1993
Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion.
    The Journal of biological chemistry, 1997, Feb-14, Volume: 272, Issue:7

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Differentiation; Cytosine; DNA Methylation; DNA Modification Methylases; Eflornithine; Enzyme Inhibitors; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; RNA, Messenger; S-Adenosylmethionine; Teratocarcinoma; Tumor Cells, Cultured

1997
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Humans; Male; Methionine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; RNA, Messenger; S-Adenosylmethionine; Tetracyclines; Thionucleosides; Tumor Cells, Cultured

2004
Mathematical modelling of polyamine metabolism in bloodstream-form Trypanosoma brucei: an application to drug target identification.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Computer Simulation; Eflornithine; Humans; Kinetics; Metabolic Networks and Pathways; Models, Chemical; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2013
Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.
    Cancer discovery, 2013, Volume: 3, Issue:9

    Topics: Animals; Cell Line, Tumor; Chemoprevention; Colorectal Neoplasms; Eflornithine; Enzyme Inhibitors; HT29 Cells; Humans; Mice; Ornithine Decarboxylase Inhibitors; S-Adenosylmethionine; Thymidine

2013
Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
    Human molecular genetics, 2018, 06-15, Volume: 27, Issue:12

    Topics: Animals; Brain; Cystathionine; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Eflornithine; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolomics; Methionine Adenosyltransferase; Mice; Neurons; Polyamines; Putrescine; S-Adenosylmethionine; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein

2018
Extracellular Spermine Activates DNA Methyltransferase 3A and 3B.
    International journal of molecular sciences, 2019, Mar-12, Volume: 20, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Cell Line, Tumor; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; Eflornithine; Epithelial Cells; Humans; Jurkat Cells; Mammary Glands, Human; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine

2019