Page last updated: 2024-08-23

s-adenosylmethionine and diphthamide

s-adenosylmethionine has been researched along with diphthamide in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (60.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Carson, DA; Kubota, M; Olavi, E; Wasson, DB; Willis, EH; Yamanaka, H1
Carson, DA; Kajander, EO; Yamanaka, H1
Moehring, JM; Moehring, TJ1
Danley, DE; Moehring, JM; Moehring, TJ1
Dzikovski, B; Ealick, SE; Freed, J; Koralewski, RM; Krebs, C; Lee, M; Lin, H; Torelli, AT; Wang, E; Zhang, Y; Zhu, X1
Lin, H1
Dando, EE; Dong, M; Du, J; Dzikovski, B; Freed, JH; Lin, H; Su, X; Zhu, X1
Dong, M; Dzikovski, B; Freed, JH; Hoffman, BM; Horitani, M; Krebs, C; Lin, H; Pandelia, ME1
Dong, M; Dzikovski, B; Ealick, SE; Freed, JH; Hoffman, BM; Horitani, M; Lin, H1
Caranto, JD; Dong, M; Dzikovski, B; Ealick, SE; Fenwick, MK; Freed, JH; Hoffman, BM; Kathiresan, V; Lancaster, KM; Lin, H; Sharma, A; Torelli, AT; Zhang, Y1
Dong, M; Lin, H; Zhang, Y2
Dando, EE; Dong, M; Dzikovski, B; Freed, JH; Kotliar, I; Lin, H; Su, X1
Chandrasekaran, S; Coleman, R; Crane, BR; Dzikovski, B; Fenwick, MK; Freed, JH; Lancaster, KM; Lin, H; Majer, SH; Su, D; Zhang, Y1
Brinkmann, U; Klassen, R; Mayer, K; Schaffrath, R; Schmidt, S; Ütkür, K1

Reviews

1 review(s) available for s-adenosylmethionine and diphthamide

ArticleYear
S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?
    Bioorganic chemistry, 2011, Volume: 39, Issue:5-6

    Topics: Adenosine; Alkylation; Cyclopropanes; Cytosine; DNA; Histidine; Methylation; Methyltransferases; Nucleosides; RNA; RNA, Ribosomal, 23S; S-Adenosylmethionine

2011

Other Studies

14 other study(ies) available for s-adenosylmethionine and diphthamide

ArticleYear
Heterogeneity of the toxic mechanisms of methylthioadenosine in methylthioadenosine phosphorylase deficient murine lymphoma cells.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenosine; Animals; Deoxyadenosines; Diphtheria Toxin; Histidine; Lymphoma; Mice; Mice, Mutant Strains; Pentosyltransferases; Peptide Elongation Factor 2; Peptide Elongation Factors; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Thionucleosides; Tumor Cells, Cultured

1989
Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells.
    Biochimica et biophysica acta, 1986, Sep-19, Volume: 888, Issue:2

    Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Cell Line; Deoxyadenosines; Diphtheria Toxin; Histidine; Lymphoma; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Thionucleosides

1986
Diphthamide: in vitro biosynthesis.
    Methods in enzymology, 1984, Volume: 106

    Topics: Amino Acids; Animals; Carbon Radioisotopes; Cell Line; Cricetinae; Cricetulus; Female; Histidine; Kinetics; Ovary; Peptide Elongation Factor 2; Peptide Elongation Factors; Protein Processing, Post-Translational; Radioisotope Dilution Technique; S-Adenosylmethionine

1984
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin.
    Molecular and cellular biology, 1984, Volume: 4, Issue:4

    Topics: Animals; Cell Line; Cricetinae; Diphtheria Toxin; Drug Resistance; Female; Histidine; Methylation; Mutation; Peptide Elongation Factor 2; Peptide Elongation Factors; Peptide Fragments; Protein Processing, Post-Translational; S-Adenosylmethionine

1984
Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.
    Nature, 2010, Jun-17, Volume: 465, Issue:7300

    Topics: Archaeal Proteins; Free Radicals; Histidine; Iron-Sulfur Proteins; Pyrococcus horikoshii; S-Adenosylmethionine

2010
Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis.
    Journal of the American Chemical Society, 2014, Feb-05, Volume: 136, Issue:5

    Topics: Archaeal Proteins; Biosynthetic Pathways; Electron Transport; Escherichia coli; Histidine; Iron-Sulfur Proteins; Protein Binding; Protein Multimerization; Pyrococcus horikoshii; Recombinant Proteins; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transfection

2014
Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme.
    Journal of the American Chemical Society, 2016, 08-10, Volume: 138, Issue:31

    Topics: Alkenes; Anisotropy; Butyrates; Carbon; Catalysis; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Electrons; Enzymes; Histidine; Iron; Iron-Sulfur Proteins; Organometallic Compounds; Pyrococcus horikoshii; S-Adenosylmethionine

2016
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
    Journal of the American Chemical Society, 2017, 04-26, Volume: 139, Issue:16

    Topics: Free Radicals; Histidine; Iron-Sulfur Proteins; Molecular Structure; Pyrococcus horikoshii; S-Adenosylmethionine; Saccharomyces cerevisiae; Substrate Specificity

2017
Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
    Science (New York, N.Y.), 2018, 03-16, Volume: 359, Issue:6381

    Topics: Archaeal Proteins; Carbon; Crystallography, X-Ray; Histidine; Iron; Iron-Sulfur Proteins; Organometallic Compounds; Pyrococcus horikoshii; S-Adenosylmethionine

2018
Noncanonical Radical SAM Enzyme Chemistry Learned from Diphthamide Biosynthesis.
    Biochemistry, 2018, 06-26, Volume: 57, Issue:25

    Topics: Biosynthetic Pathways; Histidine; Iron-Sulfur Proteins; Pyrococcus horikoshii; S-Adenosylmethionine; Substrate Specificity

2018
Methods for Studying the Radical SAM Enzymes in Diphthamide Biosynthesis.
    Methods in enzymology, 2018, Volume: 606

    Topics: Alkyl and Aryl Transferases; Archaeal Proteins; Enzyme Assays; Histidine; Peptide Elongation Factor 2; Protein Processing, Post-Translational; Pyrococcus horikoshii; S-Adenosylmethionine

2018
The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019, Volume: 24, Issue:6

    Topics: Amino Acid Sequence; Archaeal Proteins; Histidine; Iron-Sulfur Proteins; Mutation; Protein Multimerization; Pyrococcus horikoshii; S-Adenosylmethionine

2019
Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2.
    Journal of the American Chemical Society, 2021, 06-30, Volume: 143, Issue:25

    Topics: Dithionite; Histidine; Iron; Iron-Sulfur Proteins; Peptide Elongation Factor 2; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2021
    Biomolecules, 2023, Nov-16, Volume: 13, Issue:11

    Topics: Histidine; Humans; Minor Histocompatibility Antigens; Mutation; Peptide Elongation Factor 2; S-Adenosylmethionine; Saccharomyces cerevisiae; Tumor Suppressor Proteins

2023