Page last updated: 2024-08-23

s-adenosylmethionine and decitabine

s-adenosylmethionine has been researched along with decitabine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Duley, JA; Fabianowska-Majewska, K; Ruckemann, K; Simmonds, HA1
Hájek, M; Holý, A; Krecmerová, M; Tloust'ová, E; Votruba, I1
Ahn, SG; Kang, KW; Kim, HS; Kim, SK; Kim, TH; Lee, KY; Lim, SC; Phuong, NT; Yoon, JH1
Chik, F; Machnes, Z; Szyf, M1
Li, CS; Li, T; Liu, QY; Liu, WJ; Liu, ZS; Ren, JG; Yu, GZ; Zhang, J1
Bi, Y; Gao, H; Shi, X; Tian, J; Wang, W; Xu, H; Zhang, Y1
Arakelian, A; Cheishvili, D; Mahmood, N; Rabbani, SA; Szyf, M1
Audet-Walsh, E; Dufour, CR; Giguère, V; McGuirk, S; St-Pierre, J; Vernier, M; Wan, L1

Other Studies

8 other study(ies) available for s-adenosylmethionine and decitabine

ArticleYear
Effect of Cladribine, fludarabine, and 5-aza-deoxycytidine on S-adenosylmethionine (SAM) and nucleotides pools in stimulated human lymphocytes.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenine Nucleotides; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Azacitidine; Cells, Cultured; Cladribine; Cytidine Triphosphate; Decitabine; Guanine Nucleotides; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; NAD; Ribonucleotides; S-Adenosylmethionine; Uracil Nucleotides; Vidarabine

1998
Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells.
    Biochemical pharmacology, 2008, Feb-15, Volume: 75, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; HL-60 Cells; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Telomerase

2008
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; PTEN Phosphohydrolase; S-Adenosylmethionine; Tamoxifen; Tumor Burden; Xenograft Model Antitumor Assays

2011
Synergistic anti-breast cancer effect of a combined treatment with the methyl donor S-adenosyl methionine and the DNA methylation inhibitor 5-aza-2'-deoxycytidine.
    Carcinogenesis, 2014, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Matrix Metalloproteinase 2; MCF-7 Cells; S-Adenosylmethionine; Urokinase-Type Plasminogen Activator

2014
5-Aza-2<-deoxycytidine induces hepatoma cell apoptosis via enhancing methionine adenosyltransferase 1A expression and inducing S-adenosylmethionine production.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:11

    Topics: Apoptosis; Azacitidine; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methionine Adenosyltransferase; Proto-Oncogene Proteins c-bcl-2; S-Adenosylmethionine; Up-Regulation

2013
SAM targeting methylation by the methyl donor, a novel therapeutic strategy for antagonize PFOS transgenerational fertilitty toxicity.
    Ecotoxicology and environmental safety, 2019, Nov-30, Volume: 184

    Topics: Alkanesulfonic Acids; Animals; Birth Weight; Decitabine; Female; Fluorocarbons; Male; Pregnancy; Pregnancy Rate; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Reproduction; S-Adenosylmethionine; Spermatogonia; Survival Rate; Testis

2019
S-adenosylmethionine in combination with decitabine shows enhanced anti-cancer effects in repressing breast cancer growth and metastasis.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:18

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Reproducibility of Results; S-Adenosylmethionine; Transcription, Genetic; Transcriptome; Xenograft Model Antitumor Assays

2020
Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4.
    Oncogene, 2020, Volume: 39, Issue:41

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; ERRalpha Estrogen-Related Receptor; Female; Gene Expression Regulation, Neoplastic; Humans; Interferon Regulatory Factors; Mice; Promoter Regions, Genetic; Protein Stability; Receptors, Estrogen; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic; Xenograft Model Antitumor Assays

2020