s-adenosylmethionine has been researched along with adenosine in 342 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 172 (50.29) | 18.7374 |
| 1990's | 55 (16.08) | 18.2507 |
| 2000's | 46 (13.45) | 29.6817 |
| 2010's | 45 (13.16) | 24.3611 |
| 2020's | 24 (7.02) | 2.80 |
| Authors | Studies |
|---|---|
| Camardella, M; Della Pietra, G; Esposito, C; Porta, R | 1 |
| Ferro, AJ; Nicolette, JA; Wrobel, NC | 1 |
| Moss, B; Wei, CM | 1 |
| Abraham, G; Banerjee, AK; Rhodes, DP | 1 |
| Lawrence, F; Lederer, E; Robert-Gero, M; Vedel, M | 1 |
| Butt, VS; Poulton, JE | 1 |
| Glazer, RI; Peale, AL | 1 |
| Mertens, PP; Payne, CC | 2 |
| Johnston, JM; Kredich, NM | 1 |
| Borchardt, RT; Eiden, LE; Rutledge, CO; Wu, B | 1 |
| Deeprose, RD; Duncan, GS; Wolberg, G; Zimmerman, TP | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Agnoli, A; Arrigoni, E; Benzi, G; Villa, RF | 1 |
| Arnold, HH; Kersten, H; Schmidt, W | 1 |
| Coward, JK; Motola, NC; Moyer, JD | 1 |
| Edwards, CH; Edwards, GA; Freeburne, MM; Jones, EG; Seo, CW; Sherman, L; Stacey, RE; Wade, WD | 1 |
| Toohey, JI | 1 |
| Ito, S; Nicol, JA | 1 |
| Altman, NH; Brada, Z; Bulba, S | 1 |
| Fukui, S; Sugimoto, Y; Toraya, T | 1 |
| Lin, RL; Narasimhachari, N | 1 |
| Chheda, GB; Chu, J; Wainfan, E | 1 |
| Dainko, JL; Schlenk, F | 1 |
| Halper, LA; Norton, SJ | 1 |
| Borchardt, RT; Wu, YS | 2 |
| Follmann, H; Kuntz, I; Zacharias, W | 1 |
| Kiss, A; Szilák, L; Venetianer, P | 1 |
| Aarbakke, J; Andersen, A; Loennechen, T; Moens, U; Nilsen, IW | 1 |
| Szumlanski, CL; Van Loon, JA; Weinshilboum, RM | 1 |
| Follmann, H; Hogenkamp, HP; McFarlan, SC; Spormann, A; Sze, IS | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Daino, L; Feo, F; Lai, P; Pascale, R; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM; Vannini, MG | 1 |
| Borot, C; Lawrence, F; Moulay, L; Phelouzat, MA; Robert-Gero, M; Schaeverbeke, J; Schaeverbeke, M | 1 |
| Chagoya de Sánchez, V; Hernández-Muñoz, R; Sánchez, L; Suárez, J; Vidrio, S; Yáñez, L | 1 |
| Aswad, DW; Johnson, BA; Najbauer, J | 1 |
| Fujioka, M; Konishi, K | 1 |
| Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW | 1 |
| Cordier, G; Fonlupt, P; Gormand, F; Pacheco, Y; Revillard, JP | 1 |
| Bergerat, A; Guschlbauer, W | 1 |
| Duley, JA; Montero, C; Simmonds, HA; Smolenski, RT | 1 |
| Liteplo, RG | 2 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Aswad, DW; Najbauer, J | 1 |
| Friedman, S; Som, S | 1 |
| Bjorndahl, JM; Rutledge, CO | 1 |
| Benyon, RC; Church, MK; Hughes, PJ | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; Mckee, JG | 1 |
| Carson, DA; Kubota, M; Olavi, E; Wasson, DB; Willis, EH; Yamanaka, H | 1 |
| Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Gaspa, L; Pascale, R; Puddu, M; Seddaiu, MA; Simile, MM | 1 |
| Coward, JK; Pegg, AE; Poulin, R; Wechter, R; Woster, PM | 1 |
| Gharib, A; Reynaud, D; Sarda, N | 1 |
| Benghiat, E; Crooks, PA; Fuller, RW; Hassan, SF; Hemrick-Luecke, SK | 1 |
| Borchardt, RT; Cools, M; De Clercq, E; Hasobe, M; Ishii, H; McKee, JG | 1 |
| Alakuijala, L; Eloranta, TO; Lindqvist, L; Smith, TK | 1 |
| Daino, L; Donaera, A; Feo, F; Garcea, R; Pascale, R; Pirisi, L | 1 |
| Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Gaspa, L; Pascale, R; Ruggiu, ME; Vannini, MG | 1 |
| Allen, ER; Freese, E; Orrego, C; Wabiko, H | 1 |
| Coward, JK; Pegg, AE; Secrist, JA; Talekar, RR | 1 |
| Carson, DA; Kajander, EO; Yamanaka, H | 1 |
| Borchardt, RT; Decedue, CJ; Fisher, EW; Keller, BT | 1 |
| Makar, AB; Tephly, TR | 1 |
| Bacchi, CJ; Yarlett, N | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 2 |
| Augé, J; Christa, L; Kersual, J; Pérignon, JL | 1 |
| Aarsaether, N; Aarsland, A; Berge, RK; Svardal, AM; Ueland, PM | 1 |
| De Clercq, E; Durbin, RK; Stollar, V | 1 |
| Aarbakke, J; Bessesen, A; Chiang, PK; Gordon, RK; Miura, GA; Prytz, PS; Slørdal, L | 1 |
| Chiang, PK; Gordon, RK; Miura, GA; Montgomery, JA | 1 |
| Carson, DA; Kajander, EO; Kubota, M; Willis, EH | 1 |
| Brown, ND; Chiang, PK; Gordon, RK; Miura, GA; Whaun, JM | 1 |
| Hoffman, JL; McConnell, KP | 1 |
| Germain, BJ; O'Connor, CM | 1 |
| Lawrence, F; Nolan, LL; Paolantonacci, P; Robert-Géro, M | 1 |
| Boss, GR; Pilz, RB; Van den Berghe, G | 1 |
| Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Montgomery, JA | 1 |
| Fujioka, M; Ishiguro, Y | 1 |
| Hoover, KL; Hyde, CL; Poirier, LA; Wenk, ML | 1 |
| Loo, G; Smith, JT | 1 |
| Djurhuus, R; Svardal, A; Ueland, PM | 1 |
| Kufe, DW; Shafman, TD; Sherman, ML; Spriggs, DR | 1 |
| Samet, MK | 1 |
| Borchardt, RT; Clark, RS; Keller, BT; Pegg, AE | 1 |
| Kon, K; Maeda, N; Sekiya, M; Shiga, T | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Chan, VL; Ho, HJ | 1 |
| Fraki, JE; Harvima, IT; Harvima, RJ; Kajander, EO | 1 |
| Benjamin, LE; Fell, D; Steele, RD | 1 |
| Carnegie, PR; Jones, GM | 1 |
| Eskin, B; Linn, S | 2 |
| Cicala, V; Illiano, G; Utili, R | 1 |
| Cortellaro, M | 1 |
| Kerr, SJ | 1 |
| Baxter, CS; Byvoet, P | 2 |
| Kutzbach, C; Stokstad, EL | 1 |
| Fehler, SW; Light, RJ | 1 |
| Follmann, H; Gremels, G | 1 |
| Bussolotti, DL; Chang, CD; Coward, JK | 1 |
| Ceccato, S; Passeri, M | 1 |
| Murphy, JT; Spence, KD | 1 |
| Lautenberger, JA; Linn, S | 1 |
| Farber, E | 1 |
| Antoniewski, J; Cherest, H; Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Cho, TC; Talalay, P | 1 |
| Cartenì-Farina, M; Galletti, P; Servillo, L; Zappia, V | 1 |
| Isham, KR; Stulberg, MP | 1 |
| Coulter, AW; Lombardini, JB; Talalay, P | 2 |
| Hildesheim, J; Hildesheim, R; Lederer, E | 1 |
| Himwich, HE; Lin, RL; Narasimhachari, N | 1 |
| Pendleton, RG; Snow, IB | 1 |
| Finkelstein, JD; Harris, B | 1 |
| Heby, O; Russell, DH; Sauter, S | 1 |
| Dainko, JL; Schlenk, F; Zydek-Cwick, CR | 1 |
| Borchardt, RT; Huber, JA; Wu, YS | 1 |
| Ordonez, LA; Rubin, RA; Wurtman, RJ | 1 |
| Bohuon, C; Caillard, L | 1 |
| Eisenberg, MA; Stoner, GL | 1 |
| Brush, A; Paulus, H | 1 |
| Baldessarini, RJ; Matthysse, S | 1 |
| Ayala, F; Zappia, V | 1 |
| Gasbarrini, G; Labò, G; Miglio, F | 1 |
| Cavalieri, U; Leonelli, G | 1 |
| Barchas, JD; Ciaranello, RD; Dankers, HJ | 1 |
| Menci, S; Orsucci, PL | 1 |
| Lipinski, J; Matthysse, S; Shih, V | 1 |
| Lyon, GM | 1 |
| Chen, SS; Duerre, JA; Walgate, JH | 1 |
| Glazer, RI; Hartman, KD | 1 |
| Gilliland, EL; Steer, ML; Turner, N | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Ahl, R | 1 |
| Hoffman, RM | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 1 |
| Cuatrecasas, P; Deeprose, RD; Duncan, GS; Elion, GB; Schmitges, CJ; Wolberg, G; Zimmerman, TP | 1 |
| Pike, MC; Snyderman, R | 1 |
| Arnaud, M; Dante, R; Niveleau, A | 1 |
| Cooper, AJ | 1 |
| Aksamit, RR; Backlund, PS | 1 |
| Schlenk, F | 1 |
| Baglioni, C; de Ferra, F | 1 |
| Claverie, N; Danzin, C; Wagner, J | 1 |
| Bowersox, JC; Sorgente, N | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Eloranta, TO; Kajander, EO | 1 |
| Chabannes, B; Cronenberger, L; Pacheco, H; Sarda, N | 1 |
| Barber, JR; Clarke, S | 1 |
| Helland, S; Ueland, PM | 1 |
| Pegg, AE | 1 |
| Cacciapuoti, G; Cartenì-Farina, M; Della Ragione, F; Galletti, P; Zappia, V | 1 |
| Finkelstein, JD; Martin, JJ | 1 |
| Borchardt, RT; Keller, BT | 1 |
| Bartel, RL; Borchardt, RT | 1 |
| Eloranta, T; Hyvönen, T; Raina, A; Samejima, K; Voutilainen, M; Yamanoha, B | 1 |
| Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Galletti, P; Seidenfeld, J; Williams-Ashman, HG | 1 |
| Freese, E; Ochi, K | 1 |
| Borchardt, RT; Huskey, WP; Schowen, RL; Wu, SE | 1 |
| Chun, BG; Kim, S; Paik, WK | 1 |
| Hershfield, MS; Kredich, NM | 1 |
| Ferro, AJ; Law, RE | 1 |
| Hyde, CL; Poirier, LA; Rusten, R | 1 |
| McCammon, MT; Parks, LW | 1 |
| Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N | 1 |
| Chiang, PK; Montgomery, JA; Shattil, SJ | 1 |
| Eloranta, TO; Kajander, EO; Raina, AM | 1 |
| Kredich, NM; Pike, MC; Snyderman, R | 1 |
| Schlenk, F; Shapiro, SK | 1 |
| Schatz, RA; Sellinger, OZ; Wilens, TE | 2 |
| Curti, D; Raimondo, S; Villa, RF | 1 |
| Cartenì-Farina, M; Della Ragione, F; Galletti, P; Giordano, F; Manna, C; Oliva, A | 1 |
| Borchardt, RT; Chen, SY; Coward, JK; Hibasami, H; Pegg, AE | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR; Marion, DW | 1 |
| Kikuchi, S; Nishitani, H; Okumura, K; Taguchi, H | 1 |
| Buc-Calderon, P; Tinton, S | 1 |
| Finta, C; Kiss, A; Sulima, U; Venetianer, P | 1 |
| Bacchi, CJ; Garofalo-Hannan, J; Goldberg, B; Lyte, P; Rattendi, D; Yarlett, N | 1 |
| Connolly, BA; Szczelkun, MD | 1 |
| Hancock, RL | 1 |
| Gibbons, JM; Gibbons, WA; Nicolaou, A | 1 |
| De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Basselin, M; Lawrence, F; Phelouzat, MA; Robert-Gero, M | 1 |
| Blackburn, GM; Mekhalfia, A; Parsons, ID; Persson, B; Stockley, PG | 1 |
| Harding, GB; Hoffman, JL; Jacobs, AA; Lederer, ED; McLeish, KR; Robishaw, JD | 1 |
| Artymiuk, PJ; Baldwin, GS; Connolly, BA; Hornby, DP; Kelly, SM; Price, NC; Wilson, GW | 1 |
| Ault-Riché, DB; Borchardt, RT; Borcherding, DR; Hasobe, M; Lee, Y; Wolfe, MS; Yuan, CS | 1 |
| Alleman, MM; Bacchi, CJ; Dwyer, DM; Gottlieb, M; Mann, VH; Yarlett, N | 1 |
| Tsiftsoglou, AS; Vizirianakis, IS | 2 |
| Dröge, W; Fischbach, T; Germer, M; Krammer, PH; Lehmann, V; Peter, ME; Ratter, F; Schulze-Osthoff, K | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Clark, SH; Hamre, MR; Mirkin, BL | 1 |
| Bleimling, N; Kozak, M; Saenger, W; Schluckebier, G; Weinhold, E | 1 |
| Dunne, JB; Piratvisuth, T; Tredger, JM; Williams, R | 1 |
| Bacchi, CJ; Goldberg, B; Lloyd, D; Sufrin, J; Yarlett, N | 1 |
| Burke, DH; Gold, L | 1 |
| Allen, PT; Poirier, LA | 1 |
| Béliveau, R; Boivin, D; Lin, W | 1 |
| Aletta, JM; Cimato, TR; Ettinger, MJ; Zhou, X | 1 |
| De la Cruz, JP; González-Correa, JA; Mérida, M; Ortiz, P; Sánchez de la Cuesta, F | 1 |
| Janulaitis, A; Maneliene, Z; Petrusyte, M; Vitkute, J | 1 |
| Bontemps, F; Van Den Berghe, G | 1 |
| Assaraf, YG; Bunni, M; Drori, S; Jansen, G; Kathmann, I; Mauritz, RM; Peters, GJ; Pinedo, HM; Priest, DG; Schornagel, JH; Sprecher, H; Westerhof, GR | 1 |
| Derbécourt, T; Lawrence, F; Robert-Gero, M | 1 |
| Jones, PA; Shen, JC; Zingg, JM | 1 |
| Bacchi, CJ; Goldberg, B; Lloyd, D; Rattendi, D; Sufrin, JR | 1 |
| Podhajska, AJ; Tucholski, J; Zmijewski, JW | 1 |
| Bacchi, CJ; Goldberg, B; Gorrell, TE; Rattendi, D; Spiess, AJ; Sufrin, JR | 1 |
| Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B | 1 |
| Abad-Zapatero, C; Kavanaugh, TJ; Schluckebier, G; Stewart, KD; Zhong, P | 1 |
| Gumport, RI; Reich, NO; Szegedi, SS | 1 |
| Bhagwat, AS; Sharath, AN; Weinhold, E | 1 |
| Janulaitis, A; Jurenaite-Urbanaviciene, S; Kazlauskiene, R; Lubys, A; Maneliene, Z; Petrusyte, M; Urbelyte, V | 1 |
| Belloc, I; Daignan-Fornier, B; Desgranges, C; Lecoq, K | 1 |
| Lucarelli, M; Narzi, L; Orrù, L; Scarpa, S; Strom, R | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Ashihara, H; Crozier, A; Kato, A; Koshiishi, C; Yama, S | 1 |
| Hunt, CD; Ralston, NV | 1 |
| Boutz, DR; Clarke, S; Griffith, SC; Katz, JE; Sawaya, MR; Thapar, N; Yeates, TO | 1 |
| Allen, MS; Martin-McCaffrey, L; Moffatt, BA; Pereira, LA; Snider, JD; Stevens, YY; Summers, PS; Todorova, MI; Wagner, C; Weretilnyk, EA | 1 |
| Ashida, A; Inagaki, K; Kataoka, A; Shu, LY; Tamura, T; Tanaka, H | 1 |
| Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B; Osswald, H | 1 |
| Abbott, NJ; Begley, DJ; Chishty, M; Reichel, A | 1 |
| Bellas, R; Harrington, EO; Kramer, K; Lu, Q; Newton, J; Rounds, S; Sheahan, KL | 1 |
| Driskell, LO; Tucker, AM; Winkler, HH; Wood, DO | 1 |
| Iwata-Reuyl, D; Van Lanen, SG | 1 |
| Adalia, R; Agustí, M; Almenara, R; Arce, Y; Barros, P; Bombí, JA; Capdevila, L; Deulofeu, R; García-Valdecasas, JC; López-Boado, MA; Manyalich, M; Net, M; Ruiz, A; Valero, R | 1 |
| Cantoni, GL | 1 |
| DEPALMA, RE; SCHLENK, F | 2 |
| PARKS, LW; SCHLENK, F | 2 |
| MUDD, SH | 2 |
| REMY, CN | 1 |
| DAINKO, JL; SCHLENK, F; STANFORD, SM | 1 |
| YALL, I | 1 |
| Leonardi, R; Roach, PL | 1 |
| Hermes, M; Kloor, D; Mattar, J; Osswald, H | 1 |
| Hanna, GM | 1 |
| Schneller, SW; Yang, M; Ye, W | 1 |
| Bedford, MT; Cheng, D; Lee, J | 1 |
| Atta, M; Douki, T; Fontecave, M; Pierrel, F | 1 |
| Hodsdon, ME; Keeler, C; Scheuermann, TH | 1 |
| Erola, A; Jansson, A; Koskiniemi, H; Mäntsälä, P; Niemi, J; Schneider, G; Wang, J | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Fabrega, C; Hausmann, S; Lima, CD; Schneller, SW; Shuman, S; Zheng, S | 1 |
| Gabruzsk, J; Holmes, WM; Watts, JM | 1 |
| Basu, A; Bhattacharyya, S; Chaudhuri, P; Ghosh, AK; Sengupta, S | 1 |
| Petersen, SG; Rajski, SR | 1 |
| Raghavendra, NK; Rao, DN | 1 |
| Balaña-Fouce, R; Ordóñez, D; Pérez-Pertejo, Y; Reguera, RM | 1 |
| Christen, V; Duong, FH; Filipowicz, M; Heim, MH | 1 |
| Ara, AI; Chen, H; Lu, SC; Mato, JM; Ou, X; Ramani, K; Yang, H | 1 |
| Hermes, M; Kloor, D; Osswald, H | 2 |
| Chen, H; Chen, YH; Clarke, S; Josef-Lenz, H; Kuhlenkamp, J; Laird, PW; Li, T; Lin, M; Lu, SC; Mato, JM; Sodir, NM; Xia, M; Yang, H | 1 |
| Schwer, B; Shuman, S; Zheng, S | 1 |
| Bullinger, D; Fehm, T; Gleiter, CH; Kammerer, B; Laufer, S; Neubauer, H | 1 |
| Hermes, M; Kloor, D; Osswald, H; Piesch, C; Riehle, R | 1 |
| Bollati, M; Bolognesi, M; Canard, B; Coutard, B; de Lamballerie, X; Decroly, E; Mastrangelo, E; Milani, M; Nonnis, S; Ricagno, S; Selisko, B; Tedeschi, G | 1 |
| Krüger, DH; Matsumura, H; Möncke-Buchner, E; Reich, S; Reuter, M; Rothenberg, M; Terauchi, R; Wagenführ, K | 1 |
| Cui, Q; Cygler, M; Lamb, SS; Matte, A; Proteau, A; Shi, R; Sulea, T; Wright, GD; Zakeri, B | 1 |
| Bardou, F; Boissier, F; Constant, P; Daffé, M; Julien, S; Mourey, L; Ploux, O; Quémard, A; Vaubourgeix, J | 1 |
| Hanson, EA | 1 |
| Rauhala, P; Reenilä, I | 1 |
| Batey, RT; Ceres, P; Garst, AD; Mondragón, E; Montange, RK; van Tyne, D | 1 |
| Arribas, EA; Encinar, JA; Fernández, JA; García, IG; Kortazar, D; Lucas, M; Martínez-Chantar, ML; Martínez-Cruz, LA; Mato, JM; Oyenarte, I | 1 |
| Musayev, FN; O'Farrell, HC; Rife, JP; Scarsdale, JN | 1 |
| Fujimori, DG; Jomaa, H; LaMarre, JM; Mankin, AS; Röhrich, R; Wiesner, J; Yan, F | 1 |
| Chao, AT; Chung, KY; Dong, H; Lescar, J; Lim, SP; Shi, PY | 1 |
| Ahmed Ouameur, A; Dridi, L; Ouellette, M | 1 |
| Banerjee, S; Chaudhuri, P; Dutta, T; Ghosh, AK; Lahiri, S; Majhi, R; Sengupta, S | 1 |
| Basu, I; Belbin, TJ; Cassera, MB; Dong, X; Evans, GB; Guha, C; Hemeon, I; Locker, J; Merino, EF; Schramm, VL | 1 |
| Ahlum, JH; Benner, JS; Booker, SJ; Grove, TL; Krebs, C; Landgraf, BJ; Radle, MI | 1 |
| Stubbe, J | 1 |
| Goto-Ito, S; Hou, YM; Ito, T; Lahoud, G; Yokoyama, S; Yoshida, K | 1 |
| Bouvet, M; Bricogne, G; Canard, B; Coutard, B; Debarnot, C; Decroly, E; Ferron, F; Gluais, L; Imbert, I; Lescar, J; Ortiz-Lombardia, M; Papageorgiou, N; Sharff, A | 1 |
| Clarkson, AB; Merali, S; Moncada, C; Perez-Leal, O | 1 |
| Hahn, NE; Krijnen, PA; Meischl, C; Musters, RJ; Niessen, HW; Rauwerda, JA; Sipkens, JA; Smith, DE; Stehouwer, CD; van Hinsbergh, VW; Wassink, M | 1 |
| Lin, H | 1 |
| Brzezinski, K; Dauter, Z; Jaskolski, M | 1 |
| Daldrop, P; Lilley, DM; McPhee, SA; Schroeder, KT | 1 |
| Cronan, JE; Lin, S | 1 |
| Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC | 1 |
| Duley, JA; Freeman, JL; McGown, I; Munce, T; Pitt, JJ; van Werkhoven, MA | 1 |
| Combs, GF; Gabel-Jensen, C; Gammelgaard, B; Jackson, MI; Lunøe, K | 1 |
| Chu, J; Hu, X; Zhang, S; Zhuang, Y | 1 |
| Chae, SW; Park, SW; Song, JJ; Yadav, MK | 1 |
| Crécy-Lagard, Vd; Ikeuchi, Y; Kimura, S; Miyauchi, K; Suzuki, T; Thiaville, PC | 1 |
| Hsiao, HH; Liu, TP; Lo, HL; Wei, LS; Yang, PM | 1 |
| Armstrong, SA; Bradner, JE; Chory, EJ; Dhe-Paganon, S; Federation, AJ; Hadler, M; Marineau, JJ; Qi, J; Smith, WB; Souza, A; St Pierre, R; Varca, AC; Wu, L; Xu, X; Yi, JS | 1 |
| Goto-Ito, S; Hou, YM; Ito, T; Masuda, I; Sekine, S; Suh, SW; Yokoyama, S; Yoshida, K | 1 |
| Fujimori, DG; Stojković, V | 1 |
| Imiolczyk, B; Jaskolski, M; Manszewski, T; Singh, K | 1 |
| Ballhausen, D; Blom, HJ; Dionisi-Vici, C; Dobbelaere, D; Douillard, C; Freisinger, P; Grünert, SC; Haas, D; Hoffmann, GF; Kahrizi, K; Kölker, S; la Marca, G; Lindner, M; Makhseed, N; Staufner, C; Straub, BK | 1 |
| Boal, AK; Booker, SJ; Grove, TL; Schwalm, EL | 1 |
| Burkart, MD; Fin, A; Hofkens, J; Tor, Y; Tufar, P; Vranken, C | 1 |
| Doxtader, KA; Nam, Y; Wang, P | 1 |
| Laurino, P; Tawfik, DS | 1 |
| Beane, TJ; Koh, CS; Korostelev, AA; Madireddy, R; Zamore, PD | 1 |
| Du, Z; Gao, Y; Luo, Y; Wang, N; Wang, P; Wu, G; Yang, B; Zhang, Y; Zhu, Z | 1 |
| Auta, J; Bhaumik, DK; Gatta, E; Gavin, DP; Grayson, DR; Guidotti, A; Pandey, SC | 1 |
| Brown, JA; Dauter, Z; Ruszkowska, A; Ruszkowski, M | 1 |
| Chu, T; Fujimori, DG; Stojković, V; Therizols, G; Weinberg, DE | 1 |
| Droogmans, L; Feller, A; Roovers, M; Singh, RK; Van Elder, D; Versées, W; Wauters, L | 1 |
| Conrad, NK; Doxtader, KA; Nam, Y; Scarborough, AM; Seo, D; Wang, P | 1 |
| Chen, T; Ding, W; Ji, X; Mandalapu, D; Wu, R; Wu, Y; Zhang, Q | 1 |
| Beal, PA; Palumbo, CM | 1 |
| Dumbrepatil, AB; Ghosh, S; Hoff, JD; Kennedy, RT; Malec, PA; Marsh, ENG; Zegalia, KA | 1 |
| Chagoya De Sánchez, V; Chávez, E; Domínguez-López, M; Lozano-Rosas, MG; Martínez-Pérez, L; Velasco-Loyden, G | 1 |
| Eguchi, T; Kudo, F; Rohmer, M; Sato, S | 2 |
| Bulgakova, PO; Ivanov, AV; Kruglova, MP; Kubatiev, AA; Virus, ED; Vital'evich Grachev, S | 1 |
| Demmler, R; Dörner, S; Fricke, J; Gressler, M; Hoffmeister, D | 1 |
| Bhaskar, B; Carraway, KR; Mansfield, KD; Misra, S; Nance, DJ; Satterwhite, ER | 1 |
| Atdjian, C; Braud, E; Coelho, D; Ethève-Quelquejeu, M; Iannazzo, L | 1 |
| Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Ovcharenko, A; Rentmeister, A; Weissenboeck, FP | 1 |
| Ghaem Maghami, M; Höbartner, C; Lenz, AK; Scheitl, CPM | 1 |
| Bart, AG; Criscione, KR; Grunewald, GL; Lu, J; McLeish, MJ; Scott, EE; Wu, Q | 1 |
| Cheng, J; Deng, Z; Ding, W; Ji, W; Ji, X; Ma, S; Zhang, Q | 1 |
| Ali, ES; Asara, JM; Ben-Sahra, I; Gao, P; Helmin, KA; O'Hara, BP; Sahu, U; Singer, BD; Villa, E | 1 |
| Chen, KM; Delaney, K; Homolka, D; Mendel, M; Pandey, RR; Pillai, RS; Steiner, FA; Vågbø, CB; Wenda, JM | 1 |
| Alberto, JM; Coelho, D; Dreumont, N; Guéant, JL; Hergalant, S; Kundu, U; Leheup, B; Meyer, M; Mosca, P; Robert, A; Umoret, R | 1 |
| Cornelissen, NV; Hartstock, K; Kueck, NA; Ovcharenko, A; Rentmeister, A | 1 |
| Almo, SC; Arcinas, AJ; Booker, SJ; Esakova, OA; Grove, TL; Krebs, C; Wang, B; Yennawar, NH | 1 |
| Jia, G; Lu, Q; Song, P; Wang, C; Yang, J; Yu, Q; Zhang, W | 1 |
| Brown, T; Cao, M; Zheng, YG | 1 |
| Blumenthal, RM; Cheng, X; Ciogli, A; Fiorentino, F; Hajian, T; Horton, JR; Hüben, M; Mai, A; Mazzoccanti, G; Menna, M; Ren, R; Rotili, D; Vedadi, M; Weinhold, E; Yu, D; Zhang, X; Zhou, J | 1 |
| Blumenthal, RM; Cheng, X; Deng, Y; Hajian, T; Horton, JR; Huang, R; Iyamu, ID; Mai, A; Rotili, D; Vedadi, M; Yu, D; Zhang, X; Zhou, J | 1 |
| Barelier, S; Canard, B; Colmant, A; Coutard, B; Debart, F; Decroly, E; Delpal, A; Hausdorff, M; Nicollet, L; Touret, F; Vasseur, JJ | 1 |
| Gade, M; Gardner, JM; Jain, P; Laurino, P | 1 |
| Conrad, NK; Flaherty, JN; Hunter, OV; Ruiz, JC | 1 |
| Almo, SC; Fedorov, AA; Fedorov, E; Hermann, JC; Marti-Arbona, R; Raushel, FM; Shoichet, BK | 1 |
8 review(s) available for s-adenosylmethionine and adenosine
| Article | Year |
|---|---|
ATP and cell integrity.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Brain; Cell Nucleus; Cells; Ethionine; Female; Glucosephosphates; Glycerophosphates; Guinea Pigs; Hexosephosphates; Humans; Ischemia; Kidney; Liver; Male; Methionine; Mitochondria; Models, Biological; Oxidative Phosphorylation; Protein Biosynthesis; Rats; Ribosomes; RNA; S-Adenosylmethionine; Triglycerides | 1973 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Biochemistry of sulfur-containing amino acids.
Topics: Adenosine; Amino Acid Metabolism, Inborn Errors; Animals; Cysteine; Deoxyadenosines; Homocysteine; Humans; Methionine; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Structure-Activity Relationship; Sulfur; Sulfurtransferases; Thionucleosides; Thiosulfate Sulfurtransferase | 1983 |
Chemotaxis and methylation in a macrophage cell line.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1983 |
Methylthioadenosine.
Topics: Adenosine; Animals; Biotin; Deoxyadenosines; Humans; Hydrolysis; Kinetics; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; T-Phages; Thionucleosides | 1983 |
Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine.
Topics: Adenosine; Animals; Deoxyadenosines; Female; Humans; Male; Neoplasms; Purine-Nucleoside Phosphorylase; Rats; Ribosemonophosphates; S-Adenosylmethionine; Spermidine; Spermine; Thioglycosides; Thionucleosides | 1982 |
S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?
Topics: Adenosine; Alkylation; Cyclopropanes; Cytosine; DNA; Histidine; Methylation; Methyltransferases; Nucleosides; RNA; RNA, Ribosomal, 23S; S-Adenosylmethionine | 2011 |
Nucleoside analogs in the study of the epitranscriptome.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Nucleic Acid Conformation; Organophosphorus Compounds; Ribonucleotides; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Messenger; S-Adenosylmethionine; Selenium; Staining and Labeling; Transcriptome | 2019 |
334 other study(ies) available for s-adenosylmethionine and adenosine
| Article | Year |
|---|---|
Multiple forms of rabbit lung indoleamine-N-methyltransferase.
Topics: Adenosine; Animals; Chloromercuribenzoates; Chromatography, Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Lung; Male; Methionine Adenosyltransferase; Methyltransferases; Rabbits; S-Adenosylmethionine; Thionucleosides; Tryptamines | 1979 |
5-methylthioribose 1-phosphate: a product of partially purified, rat liver 5'-methylthioadenosine phosphorylase activity.
Topics: Adenosine; Animals; Female; Kinetics; Liver; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Rats; S-Adenosylmethionine; Substrate Specificity; Thioglycosides; Thionucleosides; Tubercidin | 1979 |
Methylated nucleotides block 5'-terminus of vaccinia virus messenger RNA.
Topics: Adenosine; Alkaline Phosphatase; Base Sequence; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Diphosphates; Electrophoresis; Guanosine; Methylation; Phosphorus Radioisotopes; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Tritium; Vaccinia virus | 1975 |
The 5' terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus.
Topics: Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Paper; Diphosphates; DNA-Directed RNA Polymerases; Electrophoresis, Paper; Guanosine; Guanosine Triphosphate; Methylation; Oligonucleotides; Phosphoric Diester Hydrolases; Pyrophosphatases; Ribonucleases; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1975 |
The antifungal antibiotic sinefungin as a very active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by Rous sarcoma virus.
Topics: Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Kinetics; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1978 |
Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L).
Topics: Adenosine; Caffeic Acids; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methyltransferases; N-Glycosyl Hydrolases; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Evidence that xylosyladenine affects methylation by inhibition of S-adenosyl-L-methionine synthesis.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Nucleus; Coformycin; Deoxyadenosines; In Vitro Techniques; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; S-Adenosylmethionine; Xylose | 1979 |
S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Stimulation, Chemical | 1978 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Sinefungin, a potent inhibitor or S-adenosylmethionine: protein O-methyltransferase.
Topics: Adenosine; Adrenal Glands; Animals; Antifungal Agents; Cattle; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine; Streptomyces; Structure-Activity Relationship; Thymus Gland | 1979 |
Metabolic formation of nucleoside-modified analogues of S-adenosylmethionine.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Lymphocytes; Mice; S-Adenosylmethionine; Structure-Activity Relationship | 1979 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
[Cerebral energy status and the acute hyperammoniaenia syndrome: interference of S-adenosyl-L-methionine and adenosine].
Topics: Acute Disease; Adenosine; Ammonia; Animals; Biotransformation; Brain; Dogs; Energy Metabolism; Glycolysis; Membrane Potentials; Premedication; Rest; S-Adenosylmethionine; Syndrome | 1978 |
Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA.
Topics: Adenosine; Bacillus subtilis; Borohydrides; Coenzymes; Escherichia coli; Methionine; Methylation; Methylguanidine; Micrococcus; Ribonucleosides; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Tetrahydrofolates; Uridine | 1975 |
Polyamine biosynthesis in rat prostate. Substrate and inhibitor properties of 7-deaza analogues of decarboxylated S-adenosylmethionine and 5'-methylthioadenosine.
Topics: Adenosine; Animals; Depression, Chemical; In Vitro Techniques; Kinetics; Male; Pentosyltransferases; Polyamines; Prostate; Rats; S-Adenosylmethionine; Spermidine Synthase; Tubercidin | 1977 |
Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat.
Topics: Adenosine; Aminobutyrates; Animals; Body Weight; Butyrates; Choline; Cysteine; Deoxyadenosines; Homoserine; Male; Methionine; Rats; S-Adenosylmethionine; Thionucleosides | 1977 |
Methylthio group cleavage from methylthioadenosine. Description of an enzyme and its relationship to the methylthio requirement of certain cells in culture.
Topics: Adenosine; Cell Line; Kinetics; S-Adenosylmethionine; Thiolester Hydrolases | 1977 |
Isolation of S-adenosyl-3-thiopropylamine from the eye of the sea catfish (Arius felis).
Topics: Adenosine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Eye; Fishes; Propylamines; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
The influence of DL-methionine on the metabolism of S-adenosylethionine in rats chronically treated with DL-ethionine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Body Weight; Circadian Rhythm; Ethionine; Feeding Behavior; Female; Liver; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Studies on metabolic role of 5'-Methylthioadenosine in Ochromonas malhamensis and other microorganisms.
Topics: Adenosine; Cell Membrane Permeability; Eukaryota; Methionine; N-Glycosyl Hydrolases; Ribose; S-Adenosylmethionine; Vitamin B 12 | 1976 |
Tetrahydrofolic acid: an inhibitor of the methyltetrahydrofolic acid-mediated methylation of indolethylamines.
Topics: Adenosine; Animals; Binding, Competitive; Bufotenin; Ethylamines; Homocysteine; Indoles; Lung; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Serotonin; Tetrahydrofolates | 1975 |
Tubercidin and isopropylureidopurine--inhibitors of ribothymidine synthesis in vitro.
Topics: Adenosine; Carbon Radioisotopes; Escherichia coli; Kinetics; Methylation; Purines; Ribonucleosides; RNA, Transfer; S-Adenosylmethionine; Thymidine; Tubercidin | 1975 |
The S-n-propyl analogue of S-adenosylmethionine.
Topics: Acetates; Adenosine; Guanidines; Histamine; Homocysteine; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Serotonin; Structure-Activity Relationship; Sulfides | 1975 |
Regulation of cyclopropane fatty acid biosynthesis by variations in enzyme activities.
Topics: Adenosine; Cell Division; Cyclopropanes; Fatty Acids; Homocysteine; Lactobacillus; Methyltransferases; N-Glycosyl Hydrolases; S-Adenosylmethionine; Time Factors | 1975 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 3. Modifications of the sugar portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Deoxy Sugars; Guinea Pigs; Homocysteine; Liver; Magnetic Resonance Spectroscopy; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Rats; S-Adenosylmethionine; Serotonin | 1975 |
Adenine nucleosides in solution: circular dichroism studies and base conformation.
Topics: Adenosine; Adenosine Monophosphate; Anti-Bacterial Agents; Circular Dichroism; Homocysteine; Molecular Conformation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1975 |
Purification and biochemical characterization of the EcaI DNA methyltransferase.
Topics: Adenosine; Base Sequence; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry, Physical; DNA; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; Plasmids; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Temperature | 1992 |
Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin, an indirect inhibitor of methylation?
Topics: Adenosine; Cell Nucleus; DNA; Genes, myc; Humans; Methylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Restriction Mapping; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1992 |
Human kidney thiopurine methyltransferase. Photoaffinity labeling with S-adenosyl-L-methionine.
Topics: Adenosine; Affinity Labels; Autoradiography; Chromatography, Ion Exchange; Gallic Acid; Humans; Isoenzymes; Kidney; Mercaptopurine; Methyltransferases; Photolysis; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
A possible new class of ribonucleotide reductase from Methanobacterium thermoautotrophicum.
Topics: Adenosine; Azides; Chromatography, Ion Exchange; Ethionine; Hydroxyurea; Kinetics; Methanobacterium; Ribonucleotide Reductases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Azide | 1992 |
Variations in S-adenosylmethionine, S-adenosylhomocysteine and adenosine concentrations in rat liver.
Topics: Adenosine; Animals; Circadian Rhythm; Fasting; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis.
Topics: Adenosine; Animals; Azacitidine; Biomarkers, Tumor; Deoxyadenosines; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1991 |
Leishmania donovani: antagonistic effect of S-adenosyl methionine on ultrastructural changes and growth inhibition induced by sinefungin.
Topics: Adenosine; Animals; Antiprotozoal Agents; Flagella; Golgi Apparatus; Hydrogen-Ion Concentration; Leishmania donovani; Methylation; Microscopy, Electron; Protein O-Methyltransferase; Protozoan Proteins; S-Adenosylmethionine | 1992 |
Twenty-four-hour changes of S-adenosylmethionine, S-adenosylhomocysteine adenosine and their metabolizing enzymes in rat liver; possible physiological significance in phospholipid methylation.
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Liver; Male; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1991 |
Amplification and detection of substrates for protein carboxyl methyltransferases in PC12 cells.
Topics: Adenosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hydrolysis; In Vitro Techniques; Methanol; Methylation; Methyltransferases; Proteins; Rats; S-Adenosylmethionine | 1991 |
Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide.
Topics: Adenosine; Animals; Cysteine; Enzyme Activation; Enzyme Reactivators; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glycine; Guanidinoacetate N-Methyltransferase; Iodoacetates; Iodoacetic Acid; Kinetics; Liver; Mercaptoethanol; Methyltransferases; Oxidation-Reduction; Rats; Recombinant Proteins; S-Adenosylmethionine; Spectrum Analysis; Sulfhydryl Compounds | 1991 |
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments.
Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin | 1991 |
Alteration of membrane phospholipid methylation by adenosine analogs does not affect T lymphocyte activation.
Topics: Adenosine; Antigens; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Membrane; Cells, Cultured; Humans; Leukocytes, Mononuclear; Lipids; Lymphocyte Activation; Major Histocompatibility Complex; Methylation; Phospholipids; Receptors, Antigen, T-Cell; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tritium | 1990 |
The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli.
Topics: Adenosine; Allosteric Regulation; Base Sequence; Binding Sites; Binding, Competitive; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Sodium Chloride; Temperature; Thermodynamics | 1990 |
S-adenosylmethionine increases erythrocyte ATP in vitro by a route independent of adenosine kinase.
Topics: Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Erythrocytes; Humans; In Vitro Techniques; S-Adenosylmethionine | 1990 |
Reversion to a homocysteine-responsive phenotype in a human melanoma cell line is associated with diminished growth potential and increased methionine biosynthesis.
Topics: Adenosine; Cell Division; Culture Media; Deoxyadenosines; Homocysteine; Humans; Melanoma, Experimental; Methionine; Phenotype; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Tumor Cells, Cultured | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Deoxyadenosines; Electrophoresis, Gel, Two-Dimensional; Methylation; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Pheochromocytoma; Rats; S-Adenosylmethionine; Thionucleosides; Tubercidin; Tumor Cells, Cultured | 1990 |
Direct photolabeling of the EcoRII methyltransferase with S-adenosyl-L-methionine.
Topics: Adenosine; Affinity Labels; Azides; Base Sequence; Chemical Precipitation; Dithiothreitol; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Kinetics; Mercaptoethanol; Methylation; Photochemistry; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Trichloroacetic Acid; Ultraviolet Rays | 1990 |
Effects of secretagogues on ATP levels and protein carboxyl methylation in rat brain synaptosomes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Calcimycin; Calcium; Chlorides; Egtazic Acid; Female; In Vitro Techniques; Manganese; Manganese Compounds; Methylation; Ouabain; Potassium; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; Rats; Rats, Inbred Strains; Ruthenium Red; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Cyanide; Synaptosomes; Tritium; Veratridine | 1986 |
Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Methylation; Phospholipids; S-Adenosylmethionine; Theophylline; Tubercidin | 1987 |
Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Homocysteine; Hydrolases; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1988 |
Heterogeneity of the toxic mechanisms of methylthioadenosine in methylthioadenosine phosphorylase deficient murine lymphoma cells.
Topics: Adenosine; Animals; Deoxyadenosines; Diphtheria Toxin; Histidine; Lymphoma; Mice; Mice, Mutant Strains; Pentosyltransferases; Peptide Elongation Factor 2; Peptide Elongation Factors; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Thionucleosides; Tumor Cells, Cultured | 1989 |
Inhibition of promotion and persistent nodule growth by S-adenosyl-L-methionine in rat liver carcinogenesis: role of remodeling and apoptosis.
Topics: Adenosine; Animals; Deoxyadenosines; DNA; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Phagocytosis; Phenobarbital; Phenotype; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides | 1989 |
Effect of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase, on polyamine metabolism in mammalian cells.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line, Transformed; Deoxyadenosines; Dose-Response Relationship, Drug; Fibroblasts; Leukemia L1210; Mice; Polyamines; S-Adenosylmethionine; Spermine Synthase; Thionucleosides; Transferases; Tumor Cells, Cultured | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
5'-thioadenosine derivatives as potent and selective inhibitors of histamine N-methyltransferase.
Topics: Adenosine; Adrenal Glands; Animals; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; Histamine N-Methyltransferase; In Vitro Techniques; Kinetics; Methyltransferases; Phenylethanolamine N-Methyltransferase; Rabbits; Rats; S-Adenosylmethionine; Thionucleosides | 1989 |
Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Drug Synergism; Homocysteine; Hydrolases; L Cells; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Vaccinia virus | 1989 |
Effects of dietary polyamine precursors on the metabolism and tissue concentrations of amino acids in the rat.
Topics: Adenosine; Amino Acids; Animals; Arginine; Biogenic Polyamines; Deoxyadenosines; Diet; Liver; Male; Methionine; Muscles; Ornithine; Rats; Rats, Inbred Strains; RNA, Transfer, Amino Acid-Specific; S-Adenosylmethionine; Thionucleosides | 1989 |
The variations of S-adenosyl-L-methionine content modulate hepatocyte growth during phenobarbital promotion of diethylnitrosamine-induced rat liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Adenosine; Animals; Cell Division; Deoxyadenosines; Diethylnitrosamine; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Ornithine Decarboxylase; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides | 1987 |
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Adenosine; Animals; Deoxyadenosines; Diethylnitrosamine; DNA; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides | 1987 |
An ethA mutation in Bacillus subtilis 168 permits induction of sporulation by ethionine and increases DNA modification of bacteriophage phi 105.
Topics: Adenosine; Bacillus subtilis; Bacteriophages; DNA, Viral; Ethionine; Methionine; Methylation; Mutation; S-Adenosylmethionine; Spores, Bacterial | 1986 |
Effects of certain 5'-substituted adenosines on polyamine synthesis: selective inhibitors of spermine synthase.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cells, Cultured; Eflornithine; Escherichia coli; Kinetics; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine Synthase; Spermine Synthase; Structure-Activity Relationship; Transferases | 1986 |
Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells.
Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Cell Line; Deoxyadenosines; Diphtheria Toxin; Histidine; Lymphoma; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Thionucleosides | 1986 |
Neplanocin A inhibition of S-adenosylhomocysteine hydrolase in Alcaligenes faecalis has no effect on growth of the microorganism.
Topics: Adenosine; Adenosylhomocysteinase; Alcaligenes; Bacillus subtilis; Hydrolases; N-Glycosyl Hydrolases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1987 |
The role of formate and S-adenosylmethionine in the reversal of nitrous oxide inhibition of formate oxidation in the rat.
Topics: Adenosine; Animals; Carbon Dioxide; Ethionine; Formates; Liver; Methionine; Nitrous Oxide; Oxidation-Reduction; Rats; S-Adenosylmethionine | 1987 |
Effect of DL-alpha-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis grown in a semi-defined medium.
Topics: Adenosine; Animals; Cadaverine; Chromatography, High Pressure Liquid; Culture Media; Eflornithine; Ornithine Decarboxylase; Polarography; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trichomonas vaginalis | 1988 |
In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate.
Topics: Adenosine; Animals; Betaine; Carbon Dioxide; Deoxyadenosines; Formyltetrahydrofolates; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thionucleosides; Time Factors | 1988 |
Methylthioadenosine toxicity and metabolism to methionine in mammalian cells.
Topics: Adenosine; Cell Division; Cell Line; Deoxyadenosines; Humans; Intracellular Fluid; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Thionucleosides; Tumor Cells, Cultured | 1988 |
Differential metabolic response of rat liver, kidney and spleen to ethionine exposure. S-adenosylamino acids, homocysteine and reduced glutathione in tissues.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Ethionine; Glutathione; Homocysteine; Kidney; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spleen; Time Factors | 1988 |
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay | 1988 |
DNA (cytosine) methylation in murine and human tumor cell lines treated with S-adenosylhomocysteine hydrolase inhibitors.
Topics: Adenosine; Adenosylhomocysteinase; Animals; DNA, Neoplasm; Humans; Hydrolases; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin; Tumor Cells, Cultured | 1988 |
Induction of HL-60 cell differentiation by 3-deaza-(+/-)-aristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Humans; Hydrolases; Leukemia, Myeloid, Acute; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Homocysteine; Humans; Hydrolases; Leukemia, Myeloid, Acute; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1986 |
S-adenosylmethionine metabolism as a target for adenosine toxicity.
Topics: Adenosine; Adenosine Kinase; Animals; Cell Line; Coformycin; Drug Resistance; Lymphoma; Methionine Adenosyltransferase; Mice; Pentostatin; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
Antimalarial activity of neplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Antimalarials; Erythrocytes; Humans; Hydrolases; Plasmodium falciparum; Polyamines; Purines; S-Adenosylmethionine | 1986 |
Periodate-oxidized adenosine inhibits the formation of dimethylselenide and trimethylselenonium ion in mice treated with selenite.
Topics: Adenosine; Animals; Inactivation, Metabolic; Kinetics; Liver; Methylation; Mice; Organometallic Compounds; Organoselenium Compounds; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenious Acid; Selenium; Selenium Compounds | 1987 |
Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Kinetics; Methionine; Methylation; Molecular Weight; Oocytes; S-Adenosylmethionine; Xenopus laevis | 1987 |
Inhibition of leishmanial DNA synthesis by sinefungin.
Topics: Adenosine; Animals; Cell Line; DNA Replication; Leishmania; Macrophages; Mice; Phosphorylation; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Thymidine; Transcription, Genetic | 1987 |
Adenosine dialdehyde and nitrous oxide induce HL-60 differentiation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Differentiation; Cell Division; Cell Line; Cycloleucine; Humans; Hydrolases; Nitrous Oxide; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 1987 |
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Topics: Adenosine; Animals; Cells, Cultured; Drug Resistance; Homocysteine; Kinetics; Lymphoma; Methionine; Methionine Adenosyltransferase; Mice; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
Reaction of rat liver glycine methyltransferase with 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dithiothreitol; Glycine N-Methyltransferase; Kinetics; Ligands; Liver; Mathematics; Methyltransferases; Rats; S-Adenosylmethionine | 1986 |
Ethionine carcinogenesis in CD-1, BALB/c and C3H mice.
Topics: Adenoma; Adenosine; Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Ethionine; Female; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; S-Adenosylmethionine | 1986 |
Effect of pyridoxine deficiency on phospholipid methylation in rat liver microsomes.
Topics: Adenosine; Animals; Carbon Radioisotopes; Kinetics; Male; Methylation; Microsomes, Liver; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1986 |
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1986 |
Inhibition of murine erythroleukemia cell differentiation by 3-deazaadenosine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Differentiation; Cell Line; Deoxyadenosines; Dimethyl Sulfoxide; DNA; Leukemia, Erythroblastic, Acute; Methylation; Mice; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Purification and characterization of some metabolic effects of S-neplanocylmethionine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Escherichia coli; Kinetics; L Cells; Male; Methionine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylmethionine; Substrate Specificity | 1985 |
Increase of ATP level in human erythrocytes induced by S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Erythrocyte Aging; Erythrocyte Deformability; Erythrocytes; Humans; Male; S-Adenosylmethionine; Specimen Handling | 1986 |
Levels of S-adenosylmethionine and S-adenosylethionine in four different tissues of male weanling rats during subchronic feeding of DL-ethionine.
Topics: Adenosine; Animals; Ethionine; Kidney; Liver; Male; Methionine; Pancreas; Rats; Rats, Inbred F344; S-Adenosylmethionine; Testis | 1985 |
Multiple mechanisms of adenosine toxicity in an adenosine sensitive mutant of baby hamster kidney (BHK) cells.
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Cytidine Triphosphate; Deoxyadenosines; Drug Resistance; Guanosine Triphosphate; Kidney; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Uridine Triphosphate; Vidarabine | 1985 |
Purification and partial characterization of rat kidney histamine-N-methyltransferase.
Topics: Adenosine; Animals; Chromatography, DEAE-Cellulose; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Histamine N-Methyltransferase; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Iodoacetamide; Kidney; Kinetics; Male; Methylhistamines; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1985 |
Determination of adenosine and S-adenosyl derivatives of sulfur amino acids in rat liver by high-performance liquid chromatography.
Topics: Adenosine; Amino Acids, Sulfur; Animals; Chromatography, High Pressure Liquid; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 1985 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B.
Topics: Adenosine; Adenosine Triphosphatases; Carbon Isotopes; Chromatography, DEAE-Cellulose; Coliphages; Deoxyribonucleases; DNA, Bacterial; DNA, Viral; Endonucleases; Enzyme Activation; Escherichia coli; Ethionine; Homocysteine; Kinetics; Phosphorus Isotopes; S-Adenosylmethionine; Sulfides | 1972 |
Assay of S-adenosylmethionine in human blood.
Topics: Adenosine; Carbon Isotopes; Chromatography, Ion Exchange; Humans; Methionine; Perchlorates; Radioisotope Dilution Technique; S-Adenosylmethionine; Spectrophotometry | 1971 |
[Effect of S-adenosylmethionine (SAM) on platelet aggregation. In vitro and in vivo study].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Methionine; Platelet Adhesiveness; S-Adenosylmethionine; Serotonin | 1972 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |
Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.
Topics: Acridines; Adenine; Adenosine; Animals; Arginine; Azo Compounds; Carbon Radioisotopes; Carcinogens; Cytoplasm; Dimethylformamide; Ethidium; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Male; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine.
Topics: Adenosine; Alcohol Oxidoreductases; Ammonium Sulfate; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Formaldehyde; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Rats; S-Adenosylmethionine; Spectrophotometry; Swine; Vitamin K | 1971 |
Biosynthesis of methylheptadecanes in Anabaena variabilis. In vitro incorporation of S-(methyl- 14 C)adenosylmethionine.
Topics: Adenosine; Alkanes; Bile Acids and Salts; Carbon Isotopes; Cariostatic Agents; Chromatography; Chromatography, Gas; Copper; Cyanobacteria; Dithiothreitol; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Methylation; Muramidase; NADP; Pyridinium Compounds; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Surface-Active Agents; Vibration; Zinc | 1972 |
Adenine nucleosides in solution: stabilisation of the anti-conformation by C-5' substituents.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Aminohydrolases; Binding Sites; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Molecular Conformation; Muscles; Optical Rotatory Dispersion; S-Adenosylmethionine; Solvents; Spectrophotometry, Ultraviolet | 1974 |
Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Inhibition of several methylases by S-tubercidinylhomocysteine.
Topics: Adenosine; Animals; Anti-Bacterial Agents; Catechol O-Methyltransferase Inhibitors; Homocysteine; Indoles; Kinetics; Liver; Lung; Methyltransferases; Pyrimidines; Pyrroles; Rabbits; Rats; Ribonucleosides; S-Adenosylmethionine; tRNA Methyltransferases | 1974 |
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa].
Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting | 1972 |
Transport of S-adenosylmethionine in Saccharomyces cerevisiae.
Topics: Adenosine; Azides; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Culture Media; Cyanides; Cycloheximide; Diploidy; Ethionine; Genes; Genetics, Microbial; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Temperature | 1972 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B. I. Purification, subunit structure, and catalytic properties of the modification methylase.
Topics: Adenosine; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Coliphages; DNA; DNA, Bacterial; DNA, Viral; Drug Stability; Electrophoresis, Disc; Escherichia coli; Ethionine; Homocysteine; Hydrogen-Ion Concentration; Macromolecular Substances; Methyltransferases; Molecular Weight; Osmolar Concentration; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Species Specificity; Sulfides; Tritium | 1972 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B. II. Purification, subunit structure, and catalytic properties of the restriction endonuclease.
Topics: Adenosine; Adenosine Triphosphate; Catalysis; Cations, Divalent; Centrifugation, Density Gradient; Coliphages; DNA, Bacterial; DNA, Viral; Electrophoresis, Disc; Endonucleases; Escherichia coli; Ethionine; Exonucleases; Homocysteine; Kinetics; Macromolecular Substances; Molecular Weight; Phosphorus Isotopes; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Sulfides; Tritium | 1972 |
S-adenosyl methionine-mediated repression of methionine biosynthetic enzymes in Saccharomyces cerevisiae.
Topics: Adenosine; Adenosine Triphosphate; Culture Media; Enzyme Repression; Fungal Proteins; Methionine; Mutation; Oxidoreductases; Phosphotransferases; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfites; Transferases | 1973 |
Inhibition of ATP: L-methionine S-adenosyltransferase of bakers' yeast by structural analogues of ATP.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Carbon Radioisotopes; Chromatography, Ion Exchange; Deoxyadenosines; Kinetics; Methionine; Organophosphonates; Phosphates; Protein Binding; S-Adenosylmethionine; Saccharomyces cerevisiae; Structure-Activity Relationship; Transferases | 1973 |
A coupled spectrophotometric enzyme assay for methyltransferases.
Topics: Adenosine; Aminohydrolases; Animals; Aspergillus; Brain; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis, Paper; Evaluation Studies as Topic; Guinea Pigs; Histamine; Homocysteine; Kinetics; Methods; Methyltransferases; Microchemistry; Pineal Gland; S-Adenosylmethionine; Saccharomyces cerevisiae; Serotonin; Spectrophotometry, Ultraviolet; Temperature | 1974 |
Modified nucleosides in undermethylated phenylalanine transfer RNA from Escherichia coli.
Topics: Adenosine; Amino Acyl-tRNA Synthetases; Borohydrides; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Methylation; Methyltransferases; Phenylalanine; Ribonucleosides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Tritium | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-l-methionine. I. Saturated and unsaturated aliphatic amino acids.
Topics: Adenosine; Alkylation; Amino Acids; Animals; Caproates; Carbon Radioisotopes; Chromatography, Ion Exchange; Depression, Chemical; Escherichia coli; Isomerism; Kinetics; Liver; Methionine; Molecular Conformation; Norleucine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Valerates; Valine; Yeasts | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-L-methionine. II. Aromatic amino acids.
Topics: Adenosine; Amino Acids; Animals; Electron Transport; Escherichia coli; Homocysteine; Homoserine; Hydrolysis; Liver; Malonates; Methionine; Molecular Conformation; Nitro Compounds; Phenylalanine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Tyrosine; Valerates; Yeasts | 1974 |
[New syntheses of S-adenosyl homocysteine analogues, potential methyltransferase inhibitors].
Topics: Adenosine; Carboxy-Lyases; Chromatography, Thin Layer; Homocysteine; Mass Spectrometry; Methods; Methyltransferases; Nucleosides; S-Adenosylmethionine; Spectrum Analysis | 1972 |
Inhibition of indolethylamine-N-methyltransferase by S-adenosylhomocysteine.
Topics: Adenosine; Animals; Binding, Competitive; Chromatography, Gel; Chromatography, Thin Layer; Dialysis; Ethylamines; Homocysteine; Indoles; Kinetics; Lung; Methyltransferases; Protein Binding; Rabbits; S-Adenosylmethionine; Serotonin; Spectrometry, Fluorescence; Time Factors | 1973 |
The binding order of substrates to phenylethanolamine N-methyltransferase.
Topics: Adenosine; Adrenal Glands; Animals; Binding, Competitive; Carbon Radioisotopes; Chlorobenzenes; Cyclopropanes; Dose-Response Relationship, Drug; Homocysteine; In Vitro Techniques; Kinetics; Norepinephrine; Phenylethanolamine N-Methyltransferase; Propylamines; Protein Binding; Rabbits; S-Adenosylmethionine | 1973 |
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.
Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Dithiothreitol; Glucagon; Glutathione; Growth Hormone; Homocysteine; Hydrocortisone; Isotope Labeling; Liver; Male; Methionine; Organ Specificity; Rats; S-Adenosylmethionine; Thyroxine; Tritium | 1973 |
Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-L-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone).
Topics: Adenosine; Amidines; Animals; Carboxy-Lyases; Depression, Chemical; Glyoxal; Hydrazones; Leukemia L1210; Male; Methionine; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine; Stimulation, Chemical | 1973 |
5'-Methylthioadenosine and related compounds as precursors of S-adenosylmethionine in yeast.
Topics: Adenine; Adenosine; Aerobiosis; Candida; Carbon Radioisotopes; Deoxyadenosines; Methionine; Optical Rotation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Sulfur Radioisotopes; Thionucleosides; Time Factors | 1973 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 1. Modification of the amino acid portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Computers; Guinea Pigs; Histamine; Homocysteine; Indoles; Kinetics; Liver; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Protein Binding; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1974 |
Potential inhibitor of S-adenosylmethionine-dependent methyltransferases. 2. Modification of the base portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Guinea Pigs; Histamine; Homocysteine; Indoles; Kinetics; Liver; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Protein Binding; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1974 |
Physiological dependence of brain methionine and S-adenosylmethionine concentrations on serum amino acid pattern.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Caseins; Circadian Rhythm; Dietary Carbohydrates; Dietary Proteins; Male; Methionine; Rats; S-Adenosylmethionine; Time Factors; Transferases; Tritium; Tyrosine | 1974 |
S-adenosylmethionine in human blood.
Topics: Adenosine; Adult; Child; Child, Preschool; Humans; Leukemia; Methionine; Methyltransferases; Neoplasms; Neuroblastoma; Radioisotope Dilution Technique; S-Adenosylmethionine | 1971 |
Biosynthesis of 7,8-diaminopelargonic acid, a biotin intermediate, from 7-keto-8-aminopelargonic acid and S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Amines; Amino Acids; Biotin; Cell-Free System; Chromatography, Paper; Culture Media; Electron Transport; Electrophoresis, Paper; Escherichia coli; Fatty Acids; Glucose; Keto Acids; Ketones; Magnesium; Methionine; S-Adenosylmethionine; Transaminases | 1971 |
The enzymic formation of O-acetylhomoserine in Bacillus subtilis and its regulation by methionine and S-adenosylmethionine.
Topics: Acetates; Acylation; Adenosine; Amino Acids; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Cells, Cultured; Coenzyme A; Depression, Chemical; Escherichia coli; Feedback; Homoserine; Hydroxybutyrates; Lysine; Methionine; S-Adenosylmethionine; Succinates | 1971 |
S-adenosylmethionine and catechol-O-methyl-transferase in schizophrenia.
Topics: Adenosine; Adult; Aged; Catechol O-Methyltransferase; Female; Humans; Male; Methionine; Methyltransferases; Middle Aged; S-Adenosylmethionine; Schizophrenia | 1972 |
Studies on the activation of lysine-2,3-aminomutase by (-)-S-adenosyl-L-methionine.
Topics: Adenosine; Butyrates; Carbon Isotopes; Chromatography, Thin Layer; Clostridium; Dialysis; Electrophoresis, Paper; Enzyme Activation; Isomerases; Kinetics; Lysine; Methionine; Propylamines; Protein Binding; S-Adenosylmethionine; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Trichloroacetic Acid; Ultraviolet Rays | 1972 |
[Various effects of SAM dependent transmethylations in hepatology].
Topics: Adenosine; Biopsy; Chronic Disease; Fatty Liver; Hepatitis; Humans; Injections, Intraperitoneal; Lipid Metabolism; Liver Cirrhosis; Liver Diseases; Liver Glycogen; Methionine; Methylation; S-Adenosylmethionine | 1972 |
[Preliminary clinico-geriatric trials of S-adenosylmethionine (coenzyme of biologic transmethylation)].
Topics: Adenosine; Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Injections, Intramuscular; Liver Diseases; Male; Mental Disorders; Methionine; S-Adenosylmethionine | 1972 |
The enzymatic formation of methanol from S-adenosylmethionine by various tissues of the rat.
Topics: Adenosine; Adrenal Glands; Animals; Benzoates; Brain; Carbon Isotopes; Chromatography, Paper; In Vitro Techniques; Kidney; Liver; Lung; Methanol; Methionine; Methyltransferases; Myocardium; Pancreas; Rats; S-Adenosylmethionine; Spleen; Sulfur Isotopes; Tritium | 1972 |
[Changes induced by S-adenosylmethionine (SAM) in the cholesterol and triglyceride plasma levels and in the beta-alpha lipoprotein ratio in cases of hyperlipemia. (Preliminary note)].
Topics: Adenosine; Aged; Cholesterol; Female; Humans; Hyperlipidemias; Lipid Mobilization; Lipoproteins; Male; Methionine; Middle Aged; S-Adenosylmethionine; Triglycerides | 1972 |
L-dopa and S-adenosylmethionine.
Topics: Adenosine; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Methionine; Parkinson Disease; S-Adenosylmethionine; Time Factors; Tritium | 1971 |
S-adenosylmethionine in a neuroblastoma.
Topics: Abdominal Neoplasms; Adenosine; Catechol O-Methyltransferase; Catecholamines; Chromatography; Cystathionine; Humans; Indicators and Reagents; Male; Methionine; Methods; Neoplasm Metastasis; Neuroblastoma; Norepinephrine; Orbital Neoplasms; S-Adenosylmethionine; Time Factors; Tritium; Vanilmandelic Acid | 1971 |
Oxidative deamination of sulfur amino acids by bacterial and snake venom L-amino acid oxidase.
Topics: Adenosine; Alanine; Amino Acid Oxidoreductases; Animals; Catalase; Cattle; Chromatography, Thin Layer; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Kinetics; Liver; Methionine; Models, Biological; Models, Structural; Oxygen Consumption; Proteus; S-Adenosylmethionine; Snakes; Species Specificity; Sulfides; Sulfur; Venoms | 1971 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
The effects of ethionine administration and choline deficiency on protein carboxymethylase activity in mouse pancreas.
Topics: Adenosine; Amylases; Animals; Choline Deficiency; Dietary Proteins; Ethionine; Female; Mice; Pancreas; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1981 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187.
Topics: Adenine; Adenosine; Antibodies, Anti-Idiotypic; Calcimycin; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1984 |
Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Guanosine; Lymphocytes; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline | 1982 |
Effects of 5'deoxy-5'-methylthioadenosine on the metabolism of S-adenosyl methionine.
Topics: Adenosine; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferases; Kidney; Kinetics; Rats; S-Adenosylmethionine; Sulfur Radioisotopes; Thionucleosides | 1983 |
The effects of S-adenosyl methionine (AdoMet) and its analogues on the control of transcription and translation in vitro of the mRNA products of two cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; DNA-Directed RNA Polymerases; Ethionine; Homocysteine; Insect Viruses; Kinetics; Plants; Protein Biosynthesis; Ribonucleotides; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Transcription, Genetic; Triticum | 1983 |
Correlation between growth inhibition and presence of 5'-methylthioadenosine in cells treated with interferon.
Topics: Adenosine; Adenosylhomocysteinase; Burkitt Lymphoma; Cell Division; Cell Line; Deoxyadenosines; HeLa Cells; Humans; Hydrolases; Interferon Type I; Kinetics; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1984 |
A rapid high-performance liquid chromatographic procedure for the simultaneous determination of methionine, ethionine, S-adenosylmethionine, S-adenosylethionine, and the natural polyamines in rat tissues.
Topics: Adenosine; Amino Acids, Sulfur; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethionine; Liver; Male; Methionine; Pancreas; Polyamines; Prostate; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1984 |
Fibronectin-induced protein carboxy-O-methylation in aortic endothelial cells.
Topics: Adenosine; Animals; Aorta; Cattle; Cells, Cultured; Chemotaxis; Endothelium; Fibronectins; Kinetics; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; S-Adenosylmethionine; Toyocamycin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Catabolism and lability of S-adenosyl-L-methionine in rat liver extracts.
Topics: Adenosine; Animals; Carbon Radioisotopes; Deoxyadenosines; Female; In Vitro Techniques; Liver; Proteins; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides | 1984 |
Diurnal variations of S-adenosyl-L-methionine and adenosine content in the rat pineal gland.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Effect of 2'-deoxycoformycin infusion on S-adenosylhomocysteine hydrolase and the amount of S-adenosylhomocysteine and related compounds in tissues of mice.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Coformycin; Deoxyadenosines; Homocysteine; Hydrolases; Infusions, Parenteral; Jejunum; Kidney; Kinetics; Liver; Mice; Nucleoside Deaminases; Organ Specificity; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Inhibition of aminopropyltransferases.
Topics: Adenosine; Animals; Cattle; Deoxyadenosines; In Vitro Techniques; Male; Polyamines; Rats; S-Adenosylmethionine; Spermidine Synthase; Thionucleosides; Transferases | 1983 |
High-performance liquid chromatographic analysis of adenosyl-sulfur compounds related to polyamine biosynthesis.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1983 |
Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine.
Topics: Adenosine; Animals; Betaine-Homocysteine S-Methyltransferase; Chromatography, Gel; Ethionine; Kinetics; Liver; Methyltransferases; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1984 |
Metabolic conversion of neplanocin A to S-neplanocylmethionine by mouse L 929 cells.
Topics: Adenosine; Animals; Biotransformation; L Cells; Methionine; Methyltransferases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 1984 |
Effects of adenosine dialdehyde on S-adenosylhomocysteine hydrolase and S-adenosylmethionine-dependent transmethylations in mouse L929 cells.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Hydrolases; Kinetics; L Cells; Methylation; Methyltransferases; Mice; S-Adenosylmethionine | 1984 |
Polyamine synthesis in mammalian tissues. Isolation and characterization of spermidine synthase from bovine brain.
Topics: Adenosine; Animals; Brain; Cattle; Deoxyadenosines; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Putrescine; S-Adenosylmethionine; Spermidine; Spermidine Synthase; Thionucleosides; Transferases | 1984 |
Hypomethylation of DNA in ethionine-fed rats.
Topics: Adenosine; Animals; Deoxycytidine; DNA; Ethionine; Gene Expression Regulation; Liver; Male; Methylation; Rats; Rats, Inbred F344; S-Adenosylmethionine; Time Factors | 1984 |
A decrease in S-adenosylmethionine synthetase activity increases the probability of spontaneous sporulation.
Topics: Adenosine; Bacillus subtilis; Ethionine; Guanosine Triphosphate; Methionine; Methionine Adenosyltransferase; Mutation; S-Adenosylmethionine; Selenomethionine; Spores, Bacterial; Transferases | 1982 |
Chronic cobalamin inactivation impairs folate polyglutamate synthesis in the rat.
Topics: Adenosine; Animals; Deoxyadenosines; Folic Acid; Formyltetrahydrofolates; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Vitamin B 12; Vitamin B 12 Deficiency | 1983 |
Chiral instability at sulfur of S-adenosylmethionine.
Topics: Adenosine; Chemical Phenomena; Chemistry; Deoxyadenosines; Drug Stability; Homoserine; Kinetics; Molecular Conformation; S-Adenosylmethionine; Sulfur; Thionucleosides | 1983 |
Simple separation of adenine and adenosyl-sulfur compounds by high-performance liquid chromatography.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1983 |
Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Lymphocytes; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1980 |
Inhibition of leucine transport in Saccharomyces by S-adenosylmethionine.
Topics: Adenosine; Binding, Competitive; Biological Transport; Ethionine; Kinetics; Leucine; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae | 1980 |
A thin-layer chromatographic method for the quantitative separation and estimation of S-adenosylmethionine and S-adenosylethionine in rat liver.
Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Ethionine; Female; Liver; Radioisotope Dilution Technique; Rats; Rats, Inbred F344; S-Adenosylmethionine; Tritium | 1980 |
Inhibition of sterol transmethylation by S-adenosylhomocysteine analogs.
Topics: Adenosine; Ergosterol; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Sterols; Structure-Activity Relationship | 1981 |
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution | 1982 |
The effect of pharmacologic inhibition of phospholipid methylation on human platelet function.
Topics: Adenosine; Adenosylhomocysteinase; Blood Platelets; Humans; Hydrolases; Methylation; Phosphatidylethanolamines; Phospholipids; Platelet Aggregation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1982 |
Effect of 9-beta-D-arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine, and adenosine in rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Female; Homocysteine; Hydrolases; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Role of transmethylation reactions in cellular motility and phagocytosis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adult; Animals; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Guinea Pigs; Humans; In Vitro Techniques; Lactones; Macrophages; Methylation; Models, Biological; Monocytes; Peptides; Phagocytosis; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Conversion of 5'-methylthioadenosine into S-adenosylmethionine by yeast cells.
Topics: Adenosine; Amino Acids; Candida; Cells, Cultured; Culture Media; Deoxyadenosines; S-Adenosylmethionine; Thionucleosides | 1980 |
Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Male; Methylation; Mice; Nerve Tissue Proteins; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Cerebral enzymatic activities during chronic hyperammonemia and treatment with S-adenosyl-L-methionine, adenosine and methionine in the rat.
Topics: Adenosine; Ammonia; Animals; Brain; Female; Methionine; Mitochondria; Rats; S-Adenosylmethionine | 1981 |
[Possible regulatory role of 5'-methylthioadenosine on enzymatic methyl esterification of membrane protein].
Topics: Adenine; Adenosine; Deoxyadenosines; Erythrocytes; Humans; Membrane Proteins; Methylation; Protein O-Methyltransferase; S-Adenosylmethionine; Thionucleosides | 1981 |
Studies of inhibition of rat spermidine synthase and spermine synthase.
Topics: Adenosine; Animals; Deoxyadenosines; Male; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine Synthase; Spermine Synthase; Thionucleosides; Transferases | 1980 |
S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
Topics: Adenosine; Animals; DNA; Female; Histones; Homocysteine; Kinetics; Liver; Methionine; Perfusion; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Finding of a homarine-synthesizing enzyme in turban shell and some properties of the enzyme.
Topics: Adenosine; Alkaloids; Animals; Cations, Divalent; Enzyme Inhibitors; Glycine; Invertebrates; Methyltransferases; Picolinic Acids; S-Adenosylhomocysteine; S-Adenosylmethionine; Snails; Species Specificity | 1995 |
Homocysteine enhances the inhibitory effect of extracellular adenosine on the synthesis of proteins in isolated rat hepatocytes.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Survival; Cells, Cultured; Drug Synergism; Homocysteine; Hydrolases; Inosine; Kinetics; Liver; Male; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Purification of the KpnI DNA methyltransferase and photolabeling of the enzyme with S-adenosyl-L-methionine.
Topics: Adenosine; Cloning, Molecular; Escherichia coli; Molecular Sequence Data; Protein Binding; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Ultraviolet Rays | 1995 |
Fate of soluble methionine in African trypanosomes: effects of metabolic inhibitors.
Topics: Adenosine; Animals; Half-Life; Methionine; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei | 1995 |
Sequence-specific binding of DNA by the EcoRV restriction and modification enzymes with nucleic acid and cofactor analogues.
Topics: Adenosine; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA; Escherichia coli; Magnesium; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1995 |
A specific mechanism for ethionine-induced embryonic gene activity.
Topics: Adenosine; alpha-Fetoproteins; Animals; Embryo, Mammalian; Embryo, Nonmammalian; Ethionine; Gene Expression; Liver; Liver Neoplasms, Experimental; Models, Biological; S-Adenosylmethionine | 1993 |
Biochemical mechanisms of signalling pathways for different classes of analgesic molecules.
Topics: Adenosine; Analgesia; Analgesics; Animals; Guinea Pigs; Ileum; Methionine Adenosyltransferase; Models, Biological; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; S-Adenosylmethionine; Signal Transduction | 1994 |
Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Homocysteine; Humans; Hydrolases; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Uremia | 1995 |
Sinefungin shares AdoMet-uptake system to enter Leishmania donovani promastigotes.
Topics: Adenosine; Animals; Drug Resistance; Kinetics; Leishmania donovani; Membrane Transport Proteins; Protozoan Proteins; S-Adenosylmethionine | 1995 |
Probing the molecular mechanism of action of co-repressor in the E. coli methionine repressor-operator complex using surface plasmon resonance (SPR).
Topics: Adenosine; Bacterial Proteins; Binding Sites; DNA, Bacterial; Electrochemistry; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; Kinetics; Operon; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Repressor Proteins; S-Adenosylmethionine | 1995 |
Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional responses.
Topics: Adenosine; Adenosine Diphosphate Ribose; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Periodic Acid; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; S-Adenosylmethionine; Signal Transduction; Superoxides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Ligand-induced conformational states of the cytosine-specific DNA methyltransferase M.HgaI-2.
Topics: Adenosine; Amino Acid Sequence; Base Sequence; Circular Dichroism; DNA; DNA-Cytosine Methylases; Ligands; Molecular Sequence Data; Protein Structure, Secondary; S-Adenosylmethionine | 1994 |
Effects of 4'-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Humans; Hydrolases; L Cells; Liver; Mice; Placenta; Rats; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1993 |
Crithidia luciliae: effect of purine starvation on S-adenosyl-L-methionine uptake and protein methylation.
Topics: Adenosine; Animals; Crithidia; Cycloheximide; Decarboxylation; Methionine; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Purines; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1995 |
N6-methyladenosine inhibits murine erythroleukemia cell maturation by blocking methylation of RNA and memory via conversion to S-(N6-methyl)-adenosylhomocysteine.
Topics: Adenosine; Animals; Cell Differentiation; Cell Division; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1995 |
Induction of murine erythroleukemia cell differentiation is associated with methylation and differential stability of poly(A)+ RNA transcripts.
Topics: Actins; Adenosine; Animals; Cell Differentiation; Cell Division; Cycloleucine; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Globins; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Proto-Oncogene Proteins c-myc; Ribonucleotides; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1996 |
S-adenosylhomocysteine as a physiological modulator of Apo-1-mediated apoptosis.
Topics: Adenosine; Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Apoptosis; Cytotoxicity, Immunologic; fas Receptor; L Cells; Mice; Phospholipases A; Phospholipases A2; S-Adenosylhomocysteine; S-Adenosylmethionine; Transfection | 1996 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Resistance to inhibitors of S-adenosyl-L-homocysteine hydrolase in C1300 murine neuroblastoma tumor cells is associated with increased methionine adenosyltransferase activity.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Hydrolases; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred A; Neuroblastoma; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium; Tumor Cells, Cultured | 1995 |
Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
Topics: Adenosine; Binding Sites; Catalysis; Crystallography, X-Ray; Electrochemistry; Enzyme Inhibitors; Escherichia coli; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spectrometry, Fluorescence | 1997 |
Treatment of experimental ischemia/reperfusion injury with S-adenyosylmethionine: evidence that donor pretreatment complements other regimens.
Topics: Adenosine; Allopurinol; Animals; Bile; Glutathione; Insulin; Ischemia; Liver; Liver Transplantation; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Lew; Reperfusion Injury; S-Adenosylmethionine | 1997 |
A unique transporter of S-adenosylmethionine in African trypanosomes.
Topics: Adenosine; Animals; Biological Transport; Carrier Proteins; Nucleosides; S-Adenosylmethionine; Species Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1997 |
RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX.
Topics: Adenosine; Adenosine Triphosphate; Base Sequence; Binding Sites; Conserved Sequence; Information Systems; Models, Molecular; Molecular Sequence Data; Molecular Structure; NAD; Nucleic Acid Conformation; Oligoribonucleotides; Reproducibility of Results; RNA; S-Adenosylmethionine | 1997 |
Suppression by phenobarbital of ethionine-induced hepatocellular carcinoma formation and hepatic S-adenosylethionine levels.
Topics: Adenosine; Animals; Body Weight; Ethionine; Liver; Liver Neoplasms; Male; Methylation; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1997 |
Essential arginine residues in isoprenylcysteine protein carboxyl methyltransferase.
Topics: Adenosine; Animals; Arginine; Cell Membrane; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Male; Methylation; Phenylglyoxal; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1997 |
Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.
Topics: Adenosine; Animals; Cell Differentiation; Cell-Free System; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Methionine; Methylation; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Processing, Post-Translational; Rats; S-Adenosylmethionine; Signal Transduction; Tritium | 1997 |
Effects of S-adenosyl-L-methionine on blood platelet activation.
Topics: Adenosine; Adult; Animals; Collagen; Electric Impedance; Erythrocytes; Glutathione; Humans; In Vitro Techniques; Male; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; S-Adenosylmethionine | 1997 |
BplI, a new BcgI-like restriction endonuclease, which recognizes a symmetric sequence.
Topics: Adenosine; Bacillus; Bacteriophage lambda; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; Magnesium; Plasmids; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 1997 |
Metabolism of exogenous S-adenosylmethionine in isolated rat hepatocyte suspensions: methylation of plasma-membrane phospholipids without intracellular uptake.
Topics: Adenosine; Animals; Cells, Cultured; Humans; Kinetics; Liver; Liver Diseases; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
Topics: Adenosine; Biological Transport; Carrier Proteins; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Reduced Folate Carrier Protein; S-Adenosylmethionine; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1997 |
Proton-ATPase activities involved in the uptake of an S-adenosylmethionine analogue.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Biological Transport, Active; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ionophores; Kinetics; Leishmania donovani; Proton-Motive Force; Proton-Translocating ATPases; S-Adenosylmethionine; Sodium | 1998 |
Enzyme-mediated cytosine deamination by the bacterial methyltransferase M.MspI.
Topics: Adenosine; Bacterial Proteins; Cytosine; Deamination; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Molecular Structure; Moraxella; Mutation; Neomycin; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Effects of intermediates of methionine metabolism and nucleoside analogs on S-adenosylmethionine transport by Trypanosoma brucei brucei and a drug-resistant Trypanosoma brucei rhodesiense.
Topics: Adenosine; Animals; Arsenicals; Drug Resistance; Methionine; Polyamines; Purine Nucleosides; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1998 |
Two intertwined methylation activities of the MmeI restriction-modification class-IIS system from Methylophilus methylotrophus.
Topics: Adenosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA, Bacterial; Gram-Negative Aerobic Bacteria; Methylation; Methyltransferases; S-Adenosylmethionine | 1998 |
Metabolic effects of a methylthioadenosine phosphorylase substrate analog on African trypanosomes.
Topics: Adenosine; Animals; Biological Transport; Deoxyadenosines; Methionine; Models, Chemical; Molecular Structure; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; S-Adenosylmethionine; Spermidine; Structure-Activity Relationship; Substrate Specificity; Thionucleosides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1999 |
Simultaneous determination of adenosine, S-adenosylhomocysteine and S-adenosylmethionine in biological samples using solid-phase extraction and high-performance liquid chromatography.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Humans; Kidney; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 1999 |
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
Topics: Adenosine; Amino Acid Sequence; Antifungal Agents; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Drug Resistance, Microbial; Ligands; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; RNA, Ribosomal, 23S; S-Adenosylhomocysteine; S-Adenosylmethionine | 1999 |
Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase.
Topics: Adenine; Adenosine; Binding Sites; Buffers; Carbon Radioisotopes; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; DNA; DNA Methylation; DNA-Binding Proteins; Fluorescence; Kinetics; Nucleic Acid Conformation; Protein Binding; Rhodobacter sphaeroides; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics | 2000 |
Reviving a dead enzyme: cytosine deaminations promoted by an inactive DNA methyltransferase and an S-adenosylmethionine analogue.
Topics: Adenosine; Alanine; Cysteine; Cytosine; Deamination; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Enzyme Inhibitors; Escherichia coli; Mutagenesis, Site-Directed; S-Adenosylmethionine; Serine; Uracil | 2000 |
Characterization of BseMII, a new type IV restriction-modification system, which recognizes the pentanucleotide sequence 5'-CTCAG(N)(10/8)/.
Topics: Adenosine; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; DNA Restriction Enzymes; Geobacillus stearothermophilus; Magnesium; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Protein Subunits; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity | 2001 |
Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes.
Topics: Adenosine; Adenosine Kinase; Amino Acid Sequence; Deoxyadenosines; Drug Resistance; Genes, Fungal; Molecular Sequence Data; Mutation; Phenotype; S-Adenosylmethionine; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Terminology as Topic | 2001 |
Erythroid differentiation and regulatory gene expression are modulated by adenosine derivatives interfering with S-adenosylmethionine metabolic pathway.
Topics: Adenosine; Blotting, Northern; Blotting, Southern; Cell Differentiation; Cell Division; Cell Line; Erythrocytes; Gene Expression Regulation; S-Adenosylmethionine | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine | 2001 |
Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis.
Topics: Adenosine; Boron; Dinucleoside Phosphates; Electrophoresis, Capillary; Esters; NAD; Ribose; S-Adenosylmethionine; Static Electricity | 2001 |
Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate.
Topics: Adenosine; Amino Acid Sequence; Animals; Coenzymes; Crystallography, X-Ray; Isoaspartic Acid; Isomerism; Models, Molecular; Molecular Sequence Data; Peptides; Phylogeny; Protein Conformation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Pyrococcus furiosus; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Alignment; Software; Static Electricity; Substrate Specificity | 2001 |
Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; Arabidopsis; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydrolases; Methylation; Mutation; Pectins; Phenotype; Plants, Genetically Modified; S-Adenosylhomocysteine; S-Adenosylmethionine; Seeds | 2002 |
An in vitro screening method for DNA cytosine-C5-methylase inhibitor.
Topics: Adenosine; Bacteria; Deoxyribonucleases, Type II Site-Specific; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction-Modification Enzymes; DNA-Cytosine Methylases; Electrophoresis, Agar Gel; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; S-Adenosylmethionine; Sequence Homology, Nucleic Acid; X Chromosome | 2002 |
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.
Topics: Adenosine; Animals; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
S-adenosylmethionine is substrate for carrier mediated transport at the blood-brain barrier in vitro.
Topics: Adenosine; Amino Acid Transport System L; Animals; Binding, Competitive; Biological Transport, Active; Blood-Brain Barrier; Carrier Proteins; Cell Line, Transformed; Dose-Response Relationship, Drug; Endothelium, Vascular; Kinetics; Membrane Proteins; Methionine; Models, Biological; Nucleoside Transport Proteins; Rats; S-Adenosylmethionine; Symporters; Tritium | 2002 |
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis.
Topics: Acetylcysteine; Adenosine; Animals; Apoptosis; Cattle; Cells, Cultured; Cysteine; Diterpenes; Endothelium, Vascular; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Protein Methyltransferases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; ras Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Ultraviolet Rays | 2003 |
S-adenosylmethionine transport in Rickettsia prowazekii.
Topics: Adenosine; Anion Transport Proteins; Bacterial Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Escherichia coli; Ethionine; Ethylmaleimide; Methionine; Rickettsia prowazekii; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA).
Topics: Adenosine; Binding, Competitive; Catalysis; Escherichia coli; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Nucleoside Q; Pentosyltransferases; Ribose; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Hepatic preconditioning after prolonged warm ischemia by means of S-adenosyl-L-methionine administration in pig liver transplantation from non-heart-beating donors.
Topics: Adenine Nucleotides; Adenosine; Animals; Apoptosis; Carbon Dioxide; Heart Arrest; Hepatic Artery; Ischemic Preconditioning; Liver; Liver Transplantation; Models, Animal; Necrosis; Oxygen; Portal Vein; S-Adenosylmethionine; Swine; Time Factors; Tissue Donors; Transplantation, Homologous; Xanthine | 2003 |
S-Adenosylmethionine; a new intermediate formed enzymatically from L-methionine and adenosinetriphosphate.
Topics: Adenosine; Adenosine Triphosphate; Methionine; S-Adenosylmethionine | 1953 |
The formation of S-adenosylmethionine in yeast.
Topics: Adenosine; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Yeasts | 1957 |
The preparation of S-adenosylmethionine.
Topics: Adenosine; Methionine; S-Adenosylmethionine; Yeasts | 1957 |
The stability and hydrolysis of S-adenosylmethionine; isolation of S-ribosylmethionine.
Topics: Adenosine; Hydrolysis; Methionine; Ribose; S-Adenosylmethionine | 1958 |
Formation of alpha-amino-gamma-butyrolactone from S-adenosylmethionine.
Topics: 4-Butyrolactone; Adenosine; Butyrates; Lipid Metabolism; Methionine; S-Adenosylmethionine | 1958 |
Enzymatic cleavage of S-adenosylmethionine.
Topics: Adenosine; Biophysical Phenomena; Cytokinesis; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae | 1959 |
Metabolism of 2,6-diaminopurine: S-adenosylmethionine as methyl donor for 2-methylamino-6-aminopurine synthesis.
Topics: 2-Aminopurine; Adenine; Adenosine; Metabolic Networks and Pathways; Methionine; Purines; S-Adenosylmethionine | 1959 |
Improved procedure for the isolation of S-adenosylmethionine and S-adenosylethionine.
Topics: Adenosine; Ethionine; Methionine; S-Adenosylmethionine; Yeasts | 1959 |
The mechanism of the enzymatic cleavage of S-adenosylmethionine to alpha-amino-gamma-butyrolactone.
Topics: 4-Butyrolactone; Adenosine; Amino Acids; Cytokinesis; Methionine; S-Adenosylmethionine | 1959 |
Biosynthesis of S-adenosylmethionine by Saccharomyces cerevisiae. I. Adenine and methionine requirments.
Topics: Adenine; Adenosine; Guanine; Methionine; Naphthalenes; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfonamides; Yeasts | 1962 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine | 2004 |
Influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line, Tumor; Cyclophilins; DNA Methylation; Down-Regulation; Erythropoietin; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methylation; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2004 |
NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements.
Topics: Adenine; Adenosine; Deuterium Oxide; Dietary Supplements; Magnetic Resonance Spectroscopy; Methionine; Reference Standards; S-Adenosylmethionine; Stereoisomerism; United States | 2004 |
Preparation of carbocyclic S-adenosylazamethionine accompanied by a practical synthesis of (-)-aristeromycin.
Topics: Adenosine; Aza Compounds; Molecular Conformation; S-Adenosylmethionine | 2004 |
Techniques in protein methylation.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; DNA-Binding Proteins; Enzyme Inhibitors; Glutathione Transferase; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Poly(A)-Binding Protein I; Precipitin Tests; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; RNA-Binding Proteins; S-Adenosylmethionine; Signal Transduction; Substrate Specificity | 2004 |
MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.
Topics: Adenosine; Animals; Escherichia coli; Escherichia coli Proteins; Molecular Structure; Nucleic Acid Conformation; RNA, Transfer; S-Adenosylmethionine; Sulfurtransferases; Thermotoga maritima | 2004 |
Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone.
Topics: Adenosine; Animals; Conserved Sequence; Mammals; Methyltransferases; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary; Pseudomonas syringae; S-Adenosylmethionine | 2004 |
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor.
Topics: Adenosine; Anthracyclines; Antimalarials; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coenzymes; Hydroxylation; Mass Spectrometry; Mixed Function Oxygenases; Mutagenesis; Oxygen; Protein Structure, Tertiary; S-Adenosylmethionine; Streptomyces; Substrate Specificity | 2005 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.
Topics: Adenosine; Animals; Binding Sites; Crystallization; Encephalitozoon cuniculi; Enzyme Inhibitors; Guanosine Triphosphate; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Models, Molecular; Molecular Structure; Mutagenesis; Mutation, Missense; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2005 |
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase.
Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Ligands; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Conformation; Protein Footprinting; RNA-Binding Proteins; RNA, Transfer, Leu; S-Adenosylmethionine; Sequence Alignment; Thermotoga maritima; tRNA Methyltransferases | 2005 |
Regulation of trehalose metabolism by Adox and AdoMet in Saccharomyces cerevisiae.
Topics: Adenosine; Glucosyltransferases; Methylation; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trehalase; Trehalose | 2005 |
o-nitrobenzenesulfonamides in nucleoside synthesis: efficient 5'-aziridination of adenosine.
Topics: Adenosine; Aziridines; DNA Nucleotidylexotransferase; Methylation; Methyltransferases; Molecular Mimicry; Mustard Plant; Nitrobenzenes; Nucleosides; S-Adenosylmethionine; Spectrum Analysis; Sulfonamides | 2005 |
Exogenous AdoMet and its analogue sinefungin differentially influence DNA cleavage by R.EcoP15I--usefulness in SAGE.
Topics: Adenosine; Deoxyribonucleases, Type III Site-Specific; DNA; DNA, Circular; DNA, Superhelical; Gene Expression Profiling; Repressor Proteins; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 2005 |
Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani.
Topics: Adenosine; Animals; Cloning, Molecular; Drug Resistance; Leishmania donovani; Methionine Adenosyltransferase; Neomycin; Polyamines; S-Adenosylmethionine; Trypanosomatina | 2006 |
S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro.
Topics: Adenosine; Antiviral Agents; Betaine; Cell Line; DNA; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Methylation; Phosphoprotein Phosphatases; Protein Phosphatase 2C; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Signal Transduction; STAT1 Transcription Factor; Virus Replication | 2006 |
Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.
Topics: Adenosine; Betaine-Homocysteine S-Methyltransferase; Cell Line; Cell Line, Tumor; Cloning, Molecular; DNA Primers; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Plasmids; Recombinant Proteins; S-Adenosylmethionine; Thionucleosides; Transcription, Genetic | 2007 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosylhomocysteinase; Apoptosis; Caspase Inhibitors; Caspases; Dipyridamole; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Humans; Methylation; Nucleoside Transport Proteins; Oligonucleotide Array Sequence Analysis; Pentostatin; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.
Topics: Adenine Nucleotides; Adenosine; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Chelating Agents; Culture Media; Edetic Acid; Humans; Inosine; Kinetics; Liver Neoplasms; Methylation; S-Adenosylmethionine; Time Factors; Trypsin | 2007 |
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.
Topics: Adenosine; Aged; Animals; Cell Death; Cell Division; Colonic Neoplasms; Drug Interactions; Epidermal Growth Factor; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Insulin-Like Growth Factor I; Intestinal Polyps; Leptin; Male; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Middle Aged; Mitogens; Polyamines; Promoter Regions, Genetic; S-Adenosylmethionine | 2007 |
Sinefungin resistance of Saccharomyces cerevisiae arising from Sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase.
Topics: Adenosine; Amino Acid Transport Systems; Antifungal Agents; Drug Resistance, Fungal; Methionine Adenosyltransferase; Methyltransferases; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2007 |
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.
Topics: Adenosine; Aminoimidazole Carboxamide; Biomarkers, Tumor; Breast Neoplasms; Cell Line; Cell Line, Tumor; Epithelial Cells; Female; Guanosine; Humans; Imidazoles; Ions; Mammary Glands, Human; Metabolic Networks and Pathways; Ribonucleosides; Ribose; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Uridine | 2007 |
S-Adenosylhomocysteine hydrolase overexpression in HEK-293 cells: effect on intracellular adenosine levels, cell viability, and DNA methylation.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Caspases; Cell Death; Cell Line; Cell Shape; Cell Survival; Clone Cells; DNA; DNA Fragmentation; DNA Methylation; Electrophoresis, Agar Gel; Energy Metabolism; Gene Expression Regulation, Enzymologic; Humans; Intracellular Space; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Subcellular Fractions; Transfection | 2008 |
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus.
Topics: Adenosine; Amino Acid Sequence; Binding Sites; Biological Assay; Crystallography, X-Ray; Flavivirus; Guanosine Triphosphate; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; RNA Caps; S-Adenosylmethionine; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Viral Nonstructural Proteins | 2009 |
Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target.
Topics: Adenosine; Base Sequence; Binding Sites; Deoxyribonucleases, Type III Site-Specific; DNA Methylation; DNA, Bacterial; Escherichia coli; Gene Expression Profiling; S-Adenosylmethionine; Substrate Specificity | 2009 |
Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.
Topics: Actinomycetales; Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Methyltransferases; Models, Molecular; Point Mutation; Protein Binding; Protein Multimerization; S-Adenosylhomocysteine; S-Adenosylmethionine; Teicoplanin | 2009 |
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.
Topics: Adenosine; Catalytic Domain; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Methyltransferases; Models, Molecular; Molecular Structure; Mycobacterium; Mycobacterium tuberculosis; Mycolic Acids; Protein Binding; Protein Structure, Tertiary; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2009 |
Can adenosine substitute for SAM-e as an adjunct in the treatment of depression?
Topics: Adenosine; Antidepressive Agents; Depression; Humans; Models, Theoretical; S-Adenosylmethionine | 2009 |
Simultaneous analysis of catechol-O-methyl transferase activity, S-adenosylhomocysteine and adenosine.
Topics: Adenosine; Animals; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vanillic Acid | 2010 |
Discrimination between closely related cellular metabolites by the SAM-I riboswitch.
Topics: Adenosine; Base Pairing; Conserved Sequence; Crystallography, X-Ray; Kinetics; Models, Molecular; Mutation; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Binding of S-methyl-5'-thioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pair.
Topics: Adenosine; Allosteric Regulation; Amino Acid Sequence; Archaeal Proteins; Crystallography, X-Ray; Humans; Methanococcales; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Alignment; Thionucleosides | 2010 |
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Topics: Adenosine; Base Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Fatty Acids; Methionine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; RNA, Ribosomal; RNA, Ribosomal, 16S; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2010 |
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA.
Topics: Adenosine; Amino Acid Motifs; Biocatalysis; Carbon; Escherichia coli Proteins; Hydrogen; Methyltransferases; Models, Molecular; Protein Conformation; RNA, Ribosomal; S-Adenosylmethionine | 2010 |
Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus.
Topics: Adenosine; Animals; Dengue Virus; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Methylation; Methyltransferases; RNA; S-Adenosylmethionine; Viral Proteins | 2010 |
High affinity S-Adenosylmethionine plasma membrane transporter of Leishmania is a member of the folate biopterin transporter (FBT) family.
Topics: Adenosine; Antiprotozoal Agents; Biological Transport; Biopterins; Blotting, Western; Cell Membrane; Drug Resistance, Bacterial; Folic Acid; Folic Acid Antagonists; Green Fluorescent Proteins; Leishmania; Membrane Transport Proteins; Methotrexate; Microscopy, Fluorescence; Mutation; Protozoan Proteins; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine | 2010 |
Possible regulation of trehalose metabolism by methylation in Saccharomyces cerevisiae.
Topics: Adenosine; Cell Proliferation; Gene Expression Regulation, Fungal; Hydrogen-Ion Concentration; Methylation; Protein Processing, Post-Translational; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Trehalose | 2011 |
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
Topics: Adenine; Adenosine; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxyadenosines; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylmethionine; Thionucleosides; Transplantation, Heterologous; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2011 |
A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.
Topics: Adenosine; Bacterial Proteins; Biocatalysis; Carbon; Chemical Phenomena; Cysteine; Escherichia coli; Escherichia coli Proteins; Hydrogen; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus | 2011 |
Biochemistry. The two faces of SAM.
Topics: Adenine; Adenosine; Bacterial Proteins; Biocatalysis; Catalytic Domain; Chemical Phenomena; Cysteine; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; RNA, Bacterial; RNA, Ribosomal, 23S; S-Adenosylmethionine; Staphylococcus aureus | 2011 |
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Topics: Adenosine; Drug Design; Enzyme Inhibitors; Escherichia coli Proteins; Methane; Methionine; Models, Biological; Models, Molecular; Peptide Fragments; Protein Binding; S-Adenosylmethionine; Sequence Homology; Substrate Specificity; tRNA Methyltransferases | 2011 |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.
Topics: Adenosine; Crystallization; Magnesium; Methyltransferases; Mutation; Plasmids; Protein Binding; RNA Caps; RNA, Viral; S-Adenosylmethionine; Severe acute respiratory syndrome-related coronavirus; Viral Nonstructural Proteins | 2011 |
Pneumocystis S-adenosylmethionine transport: a potential drug target.
Topics: Adenosine; Animals; Antifungal Agents; Biological Transport; Drug Delivery Systems; Fungal Proteins; Humans; Methionine Adenosyltransferase; Pneumocystis carinii; Pneumonia, Pneumocystis; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae | 2011 |
Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox).
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Membrane; Cell Nucleus; Cell Survival; Extracellular Space; Homocysteine; Intracellular Space; Membrane Glycoproteins; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Phospholipid Transfer Proteins; Rats; Reactive Oxygen Species; S-Adenosylhomocysteine; S-Adenosylmethionine; Tyrosine | 2011 |
High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus).
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Crystallography, X-Ray; Deoxyadenosines; Hydrolases; Lupinus; Methylation; Models, Molecular; Molecular Conformation; Protein Binding; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Structure and folding of a rare, natural kink turn in RNA with an A*A pair at the 2b*2n position.
Topics: Adenosine; Base Pairing; Crystallography, X-Ray; Hydrogen Bonding; Magnesium; Models, Molecular; Protein Binding; Riboswitch; RNA Folding; RNA, Fungal; S-Adenosylmethionine; Thelohania | 2012 |
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2012 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil | 2014 |
Early diagnosis of adenylosuccinate lyase deficiency using a high-throughput screening method and a trial of oral S-adenosyl-l-methionine as a treatment method.
Topics: Adenosine; Adenylosuccinate Lyase; Administration, Oral; Autistic Disorder; Child, Preschool; Chromatography, Liquid; Electroencephalography; Genotype; High-Throughput Screening Assays; Humans; Longitudinal Studies; Male; Mutation; Purine-Pyrimidine Metabolism, Inborn Errors; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization | 2013 |
Metabolism of selenite to selenosugar and trimethylselenonium in vivo: tissue dependency and requirement for S-adenosylmethionine-dependent methylation.
Topics: Adenosine; Animals; Dietary Supplements; Erythrocytes; Kidney; Liver; Male; Methylation; Molecular Weight; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenious Acid; Selenium; Selenium Compounds; Selenoproteins | 2013 |
Comparative performance of S-adenosyl-L-methionine biosynthesis and degradation in Pichia pastoris using different promoters and novel consumption inhibitors.
Topics: Adenosine; Adenosine Triphosphate; Alcohol Oxidoreductases; Ethanol; Fermentation; Fungal Proteins; Genes, Synthetic; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; Methanol; Methionine Adenosyltransferase; Pichia; Promoter Regions, Genetic; Recombinant Fusion Proteins; S-Adenosylmethionine; Spermidine; Transcription, Genetic | 2014 |
Sinefungin, a natural nucleoside analogue of S-adenosylmethionine, inhibits Streptococcus pneumoniae biofilm growth.
Topics: Adenosine; Animals; Biofilms; Colony Count, Microbial; Gene Expression Regulation, Bacterial; Homocysteine; Otitis Media; Plankton; Rats, Sprague-Dawley; S-Adenosylmethionine; Streptococcus pneumoniae | 2014 |
Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs.
Topics: Adenosine; Binding Sites; Codon; Escherichia coli Proteins; HeLa Cells; Humans; Methylation; Proteins; RNA, Transfer, Ser; RNA, Transfer, Thr; S-Adenosylmethionine; Substrate Specificity; tRNA Methyltransferases | 2014 |
S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells.
Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Survival; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Knockdown Techniques; Hep G2 Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Indazoles; Niacinamide; Phenylurea Compounds; Polycomb Repressive Complex 2; Pyridones; S-Adenosylmethionine; Sorafenib | 2015 |
Structure-guided DOT1L probe optimization by label-free ligand displacement.
Topics: Adenosine; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Neoplastic; High-Throughput Screening Assays; Histone-Lysine N-Methyltransferase; Histones; Humans; Ligands; Methylation; Methyltransferases; Models, Molecular; Phenylurea Compounds; Recombinant Fusion Proteins; S-Adenosylmethionine; Small Molecule Libraries; Structure-Activity Relationship | 2015 |
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Binding Sites; Biocatalysis; Crystallography, X-Ray; Escherichia coli Proteins; Guanine; Haemophilus influenzae; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; RNA, Transfer; S-Adenosylmethionine; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; tRNA Methyltransferases | 2015 |
Radical SAM-Mediated Methylation of Ribosomal RNA.
Topics: Adenosine; Catalysis; Escherichia coli Proteins; Methylation; Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Ribosomal; S-Adenosylmethionine; tRNA Methyltransferases | 2015 |
An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Topics: Adenosine; Adenosylhomocysteinase; Bacterial Proteins; Binding Sites; Biocatalysis; Bradyrhizobium; Crystallography, X-Ray; Escherichia coli; Gene Expression; Homocysteine; Models, Molecular; NAD; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options.
Topics: Adenosine; Adenosine Kinase; Adolescent; Adult; Biomarkers; Child; Child, Preschool; Diet; Female; Humans; Hypoglycemia; Infant; Liver; Liver Diseases; Male; Metabolic Diseases; Methionine; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult | 2016 |
Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Topics: Adenosine; Alanine; Amino Acid Substitution; Anticodon; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli Proteins; Methylation; Methyltransferases; Nucleic Acid Conformation; Protein Structure, Tertiary; RNA, Bacterial; RNA, Transfer, Glu; S-Adenosylmethionine | 2016 |
Chemoenzymatic synthesis and utilization of a SAM analog with an isomorphic nucleobase.
Topics: Adenosine; Biocatalysis; Methionine; Methyltransferases; Molecular Structure; S-Adenosylmethionine | 2016 |
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Topics: Adenosine; Allosteric Regulation; Binding Sites; Catalytic Domain; HEK293 Cells; Humans; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Conformation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 2016 |
Spontaneous Emergence of S-Adenosylmethionine and the Evolution of Methylation.
Topics: Adenosine; Adenosine Triphosphate; Methylation; Methyltransferases; Nucleic Acid Conformation; S-Adenosylmethionine | 2017 |
Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine.
Topics: Adenosine; Binding Sites; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Pseudouridine; RNA, Ribosomal, 23S; S-Adenosylmethionine; Substrate Specificity | 2017 |
Metabolic perturbation of epigenome by inhibiting S-adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells.
Topics: Adenosine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Proliferation; Cellular Senescence; Chromatin; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Epigenomics; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 2017 |
Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABAA Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD).
Topics: Adenosine; Alcoholism; Carbon; Cerebellum; Chromatography, High Pressure Liquid; Cohort Studies; DNA Methylation; Female; Gene Expression; Humans; Immunoprecipitation; Male; Middle Aged; Mixed Function Oxygenases; Postmortem Changes; Promoter Regions, Genetic; Proto-Oncogene Proteins; Receptors, GABA-A; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction | 2017 |
Structural insights into the RNA methyltransferase domain of METTL16.
Topics: Adenosine; Binding Sites; Crystallography, X-Ray; Humans; Methyltransferases; RNA; RNA, Long Noncoding; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2018 |
miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes.
Topics: Adenosine; Cysteine; Escherichia coli; Escherichia coli Proteins; Immunoprecipitation; Methylation; Methyltransferases; Mutation; RNA; S-Adenosylmethionine; Sequence Analysis, RNA; Substrate Specificity | 2018 |
Structural and biochemical analysis of the dual-specificity Trm10 enzyme from
Topics: Adenosine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Guanosine; Models, Molecular; Molecular Docking Simulation; RNA Processing, Post-Transcriptional; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Thermococcus; tRNA Methyltransferases | 2018 |
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Topics: 3' Untranslated Regions; Adenosine; Binding Sites; HEK293 Cells; Homeostasis; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2018 |
Radical SAM-dependent adenosylation catalyzed by l-tyrosine lyases.
Topics: Adenosine; Biocatalysis; Free Radicals; Molecular Structure; S-Adenosylmethionine; Tyrosine Phenol-Lyase | 2019 |
Viperin interacts with the kinase IRAK1 and the E3 ubiquitin ligase TRAF6, coupling innate immune signaling to antiviral ribonucleotide synthesis.
Topics: Adenosine; Antiviral Agents; Cytidine Triphosphate; Half-Life; HEK293 Cells; Humans; Immunity, Innate; Interleukin-1 Receptor-Associated Kinases; Intracellular Signaling Peptides and Proteins; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Protein Binding; Proteins; S-Adenosylmethionine; Signal Transduction; TNF Receptor-Associated Factor 6; Ubiquitination | 2019 |
Diminished S-adenosylmethionine biosynthesis and its metabolism in a model of hepatocellular carcinoma is recuperated by an adenosine derivative.
Topics: Adenosine; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Rats; Rats, Wistar; RNA-Binding Proteins; S-Adenosylmethionine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5'-Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C
Topics: Adenosine; Bacterial Proteins; Catalysis; Humans; S-Adenosylmethionine; Triterpenes | 2020 |
Determination of S-adenosylmethionine, S-adenosylhomocysteine, and methylthioadenosine in urine using solvent-modified micellar electrokinetic chromatography.
Topics: Adenosine; Adolescent; Adult; Child; Child, Preschool; Chromatography, Micellar Electrokinetic Capillary; Female; Humans; Limit of Detection; Linear Models; Male; Middle Aged; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Young Adult | 2020 |
S-Adenosyl-l-Methionine Salvage Impacts Psilocybin Formation in "Magic" Mushrooms.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Gene Expression Profiling; Psilocybe; Psilocybin; S-Adenosylmethionine | 2020 |
Characterization of METTL16 as a cytoplasmic RNA binding protein.
Topics: Adenosine; Cytoplasm; HEK293 Cells; HeLa Cells; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; Nuclear Proteins; RNA Splicing; RNA Stability; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine | 2020 |
Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups.
Topics: Adenosine; Humans; Methylation; Methyltransferases; RNA Processing, Post-Transcriptional; RNA, Messenger; S-Adenosylmethionine; Triazoles | 2020 |
High-resolution structures of the SARS-CoV-2 2'-
Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins | 2020 |
Tag-Free Internal RNA Labeling and Photocaging Based on mRNA Methyltransferases.
Topics: Adenosine; Chromatography, High Pressure Liquid; Click Chemistry; Humans; Light; Methyltransferases; Photolysis; RNA, Messenger; S-Adenosylmethionine; Substrate Specificity; Tandem Mass Spectrometry | 2021 |
Site-specific RNA methylation by a methyltransferase ribozyme.
Topics: Adenosine; Base Sequence; Biocatalysis; Guanine; Methylation; Methyltransferases; Plasmids; RNA, Catalytic; RNA, Transfer; S-Adenosylmethionine | 2020 |
Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine
Topics: Adenosine; Binding Sites; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Isoquinolines; Models, Molecular; Phenylethanolamine N-Methyltransferase; Protein Domains; S-Adenosylmethionine; Structure-Activity Relationship | 2020 |
Characterization and Mechanistic Study of the Radical SAM Enzyme ArsS Involved in Arsenosugar Biosynthesis.
Topics: Adenosine; Alkylation; Arsenates; Arsenites; Catalysis; Drug and Narcotic Control; Escherichia coli; Free Radicals; Monosaccharides; Oxidation-Reduction; S-Adenosylmethionine; Signal Transduction; Tandem Mass Spectrometry | 2021 |
mTORC1 stimulates cell growth through SAM synthesis and m
Topics: Adenosine; Animals; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Proliferation; Female; HEK293 Cells; HeLa Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Methionine Adenosyltransferase; Methylation; Mice, Nude; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; RNA Splicing Factors; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic | 2021 |
Splice site m
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Conserved Sequence; Diet; HeLa Cells; Humans; Introns; Methionine Adenosyltransferase; Methylation; Methyltransferases; Mice; Mutation; Nucleic Acid Conformation; Protein Binding; RNA Precursors; RNA Splice Sites; RNA Splicing; RNA, Messenger; RNA, Small Nuclear; S-Adenosylmethionine; Splicing Factor U2AF; Transcriptome | 2021 |
Vitamin B
Topics: Adenosine; Animals; Fibroblasts; Gene Expression Regulation; Methylation; Mice, Knockout; Protein Kinase C-alpha; Receptors, Cell Surface; Recombinant Fusion Proteins; RNA, Messenger; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 Deficiency | 2021 |
Biochemical and Mutational Analysis of Radical
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine; Bacterial Proteins; Catalysis; Cysteine; S-Adenosylmethionine; Triterpenes; Zymomonas | 2021 |
Chemoenzymatic labeling of RNA to enrich, detect and identify methyltransferase-target sites.
Topics: Adenosine; Methionine; Methyltransferases; RNA; S-Adenosylmethionine | 2021 |
Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Topics: Adenosine; Bacteroides; Binding Sites; Biocatalysis; Isopentenyladenosine; Methyltransferases; Models, Molecular; Protein Domains; RNA; RNA-Binding Proteins; RNA, Transfer; S-Adenosylmethionine; Substrate Specificity; Sulfhydryl Compounds; Sulfurtransferases | 2021 |
FIONA1 is an RNA N
Topics: Adenosine; Animals; Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Plant; Mammals; Methyltransferases; RNA; S-Adenosylmethionine | 2022 |
Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors.
Topics: Adenosine; Arginine; Cell Line, Tumor; Enzyme Inhibitors; Molecular Docking Simulation; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Triazoles | 2022 |
Systematic Design of Adenosine Analogs as Inhibitors of a
Topics: Adenine; Adenosine; Animals; Clostridioides difficile; DNA; Humans; Mammals; Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2023 |
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a
Topics: Adenine; Adenosine; Clostridioides difficile; Clostridium Infections; DNA; Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 2023 |
Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases.
Topics: Adenine; Adenosine; Antiviral Agents; COVID-19; Humans; Methyltransferases; Pandemics; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2023 |
Nucleoside-Driven Specificity of DNA Methyltransferase.
Topics: Adenosine; DNA; DNA Methylation; Methionine; Methyltransferases; Nucleosides; S-Adenosylmethionine | 2023 |
Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of
Topics: 3' Untranslated Regions; Adenosine; Chromosomal Proteins, Non-Histone; Gene Expression Regulation; Humans; Methionine Adenosyltransferase; Methylation; Methyltransferases; RNA, Messenger; S-Adenosylmethionine | 2023 |
Structure-based activity prediction for an enzyme of unknown function.
Topics: Adenine; Catalysis; Crystallography, X-Ray; Deamination; Deoxyadenosines; Enzymes; Homocysteine; Inosine; Models, Molecular; Nucleoside Deaminases; Protein Conformation; S-Adenosylhomocysteine; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; Thionucleosides | 2007 |