Compounds > s-adenosylmethionine
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s-adenosylmethionine and acetylcysteine

s-adenosylmethionine has been researched along with acetylcysteine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.13)18.7374
1990's12 (30.77)18.2507
2000's11 (28.21)29.6817
2010's12 (30.77)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Shimizu, H; Suzuki, S; Tateishi, M1
Bray, GP; Tredger, JM; Williams, R1
Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW1
Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Pascale, R; Ruggiu, ME; Vannini, MG1
Cabello Porras, MR; Cantoni, L; Carelli, M; Rizzardini, M1
Davenport, M; Dunne, JB; Tredger, JM; Williams, R1
Devi, BG; Frosto, TA; Henderson, GI; Schenker, S1
Bilton, D; Bottiglieri, T; Braganza, JM; Chaloner, C; Hunt, LP; Schofield, D; Scott, P; Shiel, N1
Borchardt, RT; Capdevila, A; Decha-Umphai, W; Song, KH; Wagner, C1
Kowluru, A; Li, G; Metz, SA1
Ballesta, A; Colell, A; Fernández-Checa, JC; García-Ruiz, C; Kaplowitz, N; Morales, A; Ookhtens, M; Rodés, J1
Brown, LA; Guidot, DM; Holguin, F; Moss, I1
Bosch-Morell, F; Colell, A; Fernández-Checa, JC; Martínez-Soriano, F; Romero, FJ1
Chawla, RK; Watson, WH; Zhao, Y1
Carrasco, R; Caturla, J; Esteban, A; Gutiérrez, A; Mayol, MJ; Ortiz, P; Pérez-Mateo, M1
Bellas, R; Harrington, EO; Kramer, K; Lu, Q; Newton, J; Rounds, S; Sheahan, KL1
Barve, S; Chen, T; Deaciuc, IV; Hill, D; McClain, CJ; Song, Z; Uriarte, S1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Graves, M; Ortiz, D; Rogers, E; Shea, TB; Tchantchou, F1
Al-Osaimi, AM; Argo, CK; Caldwell, SH; Chang, CY1
Carpenter, AB; Kiningham, KK; Sullivan, SB; Terneus, MV; Valentovic, MA1
Chan, A; Shea, TB1
Brown, JM; Carpenter, AB; Terneus, MV; Valentovic, MA1
Arellanes-Robledo, J; Beltrán-Ramírez, O; Fattel-Fazenda, S; García-Román, R; Rosas, S; Salazar-González, D; Villa-Treviño, S1
Cooper, J; Webster, CR1
Moreno-Otero, R; Trapero-Marugán, M1
Cui, Y; Han, ZJ; Ma, X; Song, G; Xia, HF1
Alvarez-Velilla, R; Balaña-Fouce, R; Estrada, CG; Pérez-Pertejo, Y; Reguera, RM1
Cacciapuoti, F1
Chayanupatkul, M; Liangpunsakul, S1
Hovda, LR; Schmid, RD1
Bataller, R; Cabezas, J1
da Rosa, MS; Leipnitz, G; Ribeiro, RT; Seminotti, B; Wajner, M; Wyse, ATS; Zanatta, Â1
Gu, B; Song, Y; Tan, X; Yang, L; Zhou, T; Zong, Y1
Cantley, LC; Dai, Z; Hwang, I; Li, F; Locasale, JW; Paik, J; Sanchez, T; Uchida, H; Zheng, H1
Aithal, GP; Alvarez-Alvarez, I; Andrade, RJ; Arikan, C; Atallah, E; Lucena, MI; Medina-Caliz, I; Niu, H1
Curry, SC; Jaeschke, H; Li, F; Ma, X; McGill, MR; Sharpe, MR; Williams, CD1
Beger, RD; Bhattacharyya, S; Gill, P; James, LP; Kearns, GL; Letzig, LG; Marshall, JD; Pence, L; Reed, MD; Simpson, PM; Sullivan, JE; Van Den Anker, JN; Yan, K1
Bastin, J; Bennett, MJ; Chen, J; Doulias, PT; Ischiropoulos, H; Tenopoulou, M1

Reviews

4 review(s) available for s-adenosylmethionine and acetylcysteine

ArticleYear
Therapy of NAFLD: antioxidants and cytoprotective agents.
    Journal of clinical gastroenterology, 2006, Volume: 40 Suppl 1

    Topics: Acetylcysteine; Antioxidants; Betaine; Cholagogues and Choleretics; Disease Progression; Fatty Liver; Humans; Lipid Peroxidation; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E

2006
Therapeutic use of cytoprotective agents in canine and feline hepatobiliary disease.
    The Veterinary clinics of North America. Small animal practice, 2009, Volume: 39, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Biliary Tract Diseases; Cat Diseases; Cats; Cholagogues and Choleretics; Cryoprotective Agents; Dog Diseases; Dogs; Free Radical Scavengers; Liver Diseases; S-Adenosylmethionine; Silymarin; Ursodeoxycholic Acid; Vitamin E

2009
Alcoholic hepatitis: a comprehensive review of pathogenesis and treatment.
    World journal of gastroenterology, 2014, May-28, Volume: 20, Issue:20

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcoholism; End Stage Liver Disease; Enteral Nutrition; Hepatitis, Alcoholic; Humans; Immunity, Innate; Inflammation; Liver Transplantation; Pentoxifylline; Propylthiouracil; S-Adenosylmethionine; Treatment Outcome

2014
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adrenal Cortex Hormones; Adult; Carnitine; Chemical and Drug Induced Liver Injury; Child; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glycyrrhizic Acid; Humans; Infant, Newborn; Liver; Liver Failure, Acute; Retrospective Studies; S-Adenosylmethionine; Ursodeoxycholic Acid

2022

Trials

2 trial(s) available for s-adenosylmethionine and acetylcysteine

ArticleYear
Evidence for early oxidative stress in acute pancreatitis. Clues for correction.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1995, Volume: 17, Issue:1

    Topics: Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antioxidants; Discriminant Analysis; Free Radical Scavengers; Humans; Linoleic Acid; Linoleic Acids; Middle Aged; Oxidative Stress; Pancreatitis; S-Adenosylmethionine

1995
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005

Other Studies

33 other study(ies) available for s-adenosylmethionine and acetylcysteine

ArticleYear
The metabolism of bromazepam in the rat--identification of mercapturic acid and its conversion in vitro to methylthio-bromazepam.
    Biochemical pharmacology, 1978, Mar-01, Volume: 27, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Anxiety Agents; Bile; Biotransformation; Bromazepam; In Vitro Techniques; Male; Rats; S-Adenosylmethionine

1978
S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mortality; S-Adenosylmethionine

1992
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Apr-15, Volume: 88, Issue:8

    Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin

1991
Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Animals; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Ethanol; Female; Glutathione; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase

1989
Mechanisms of endotoxin-induced haem oxygenase mRNA accumulation in mouse liver: synergism by glutathione depletion and protection by N-acetylcysteine.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Escherichia coli; Glutathione; Heme Oxygenase (Decyclizing); Lipopolysaccharides; Liver; Male; Methionine Sulfoximine; Mice; Oxidative Stress; RNA, Messenger; S-Adenosylmethionine

1994
Evidence that S-adenosylmethionine and N-acetylcysteine reduce injury from sequential cold and warm ischemia in the isolated perfused rat liver.
    Transplantation, 1994, Apr-27, Volume: 57, Issue:8

    Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Bile; Cold Temperature; Hot Temperature; Ischemia; Liver; Male; Oxygen; Oxygen Consumption; Rats; Rats, Inbred Lew; Regional Blood Flow; Reperfusion Injury; S-Adenosylmethionine; Time Factors

1994
Effect of ethanol on rat fetal hepatocytes: studies on cell replication, lipid peroxidation and glutathione.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:3

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Cell Division; Cells, Cultured; Endoplasmic Reticulum; Ethanol; Fetus; Glutathione; Intracellular Membranes; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Microscopy, Electron; Mitochondria, Liver; Oxidants; Peroxides; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Thymidine; Time Factors

1993
Pancreatic exocrine secretion is blocked by inhibitors of methylation.
    Archives of biochemistry and biophysics, 1997, Sep-01, Volume: 345, Issue:1

    Topics: Acetylcysteine; Amylases; Animals; Antimetabolites; Cell Line; Enzyme Inhibitors; Ethionine; GTP-Binding Proteins; Male; Methylation; Methyltransferases; Pancreas; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Sincalide

1997
Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.
    The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6

    Topics: 3-O-Methylglucose; Acetylcysteine; Animals; Calcium; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Glucose; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Male; Methylation; Mycophenolic Acid; Peptides; Pertussis Toxin; Potassium; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Virulence Factors, Bordetella; Wasp Venoms

1997
Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: effect of membrane physical properties and S-adenosyl-L-methionine.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3

    Topics: Acetylcysteine; Adenosine Diphosphate; Adenosine Triphosphate; Alcoholism; Animals; Ethanol; Fluorescence Polarization; Glutathione; Intracellular Membranes; Kinetics; Male; Membrane Fluidity; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine

1997
Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Acetylcysteine; Acute Disease; Alcohol Drinking; Animals; Bacterial Toxins; Bronchoalveolar Lavage Fluid; Causality; Cell Survival; Chemotherapy, Cancer, Regional Perfusion; Endotoxins; Ethanol; Glutathione; Homeostasis; Lung; Lung Injury; Male; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine

1998
Chronic ethanol feeding induces cellular antioxidants decrease and oxidative stress in rat peripheral nerves. Effect of S-adenosyl-L-methionine and N-acetyl-L-cysteine.
    Free radical biology & medicine, 1998, Volume: 25, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ethanol; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Microscopy, Electron; Oxidative Stress; Peripheral Nerves; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine

1998
S-adenosylmethionine attenuates the lipopolysaccharide-induced expression of the gene for tumour necrosis factor alpha.
    The Biochemical journal, 1999, Aug-15, Volume: 342 ( Pt 1)

    Topics: Acetylcysteine; Animals; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Lipopolysaccharides; Liver; Macrophages; Male; Mice; Organometallic Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylmethionine; Time Factors; Tumor Necrosis Factor-alpha

1999
Effect of different doses of S-adenosyl-L-methionine on paracetamol hepatotoxicity in a mouse model.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:10

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Female; Free Radical Scavengers; Liver; Liver Failure; Mice; S-Adenosylmethionine

2000
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis.
    Molecular biology of the cell, 2003, Volume: 14, Issue:3

    Topics: Acetylcysteine; Adenosine; Animals; Apoptosis; Cattle; Cells, Cultured; Cysteine; Diterpenes; Endothelium, Vascular; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Protein Methyltransferases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; ras Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Ultraviolet Rays

2003
Modulation of endotoxin stimulated interleukin-6 production in monocytes and Kupffer cells by S-adenosylmethionine (SAMe).
    Cytokine, 2004, Dec-21, Volume: 28, Issue:6

    Topics: Acetylcysteine; Animals; Cycloleucine; Down-Regulation; Glutathione; Interleukin-6; Kupffer Cells; Lipopolysaccharides; Mice; Monocytes; S-Adenosylmethionine

2004
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration.
    Neuromolecular medicine, 2004, Volume: 6, Issue:2-3

    Topics: Acetylcysteine; Animals; Apolipoproteins E; Cell Line, Tumor; Dietary Supplements; Disease Models, Animal; Folic Acid Deficiency; Glutathione; Glutathione Synthase; Maze Learning; Mice; Mice, Knockout; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Tubercidin; Vitamin E Deficiency

2004
Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Aldehydes; Animals; Antidotes; Blotting, Western; Glutathione; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Protein Carbonylation; S-Adenosylmethionine

2007
Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4.
    Neuromolecular medicine, 2007, Volume: 9, Issue:3

    Topics: Acetylcarnitine; Acetylcysteine; Aggression; Animals; Apolipoprotein E4; Cognition; Dietary Supplements; Humans; Mice; Mice, Transgenic; Oxidation-Reduction; S-Adenosylmethionine

2007
Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose.
    Toxicology, 2008, Feb-03, Volume: 244, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Aldehydes; Analysis of Variance; Animals; Blotting, Western; Drug Overdose; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Microscopy, Polarization; Organ Size; Protein Carbonylation; S-Adenosylmethionine; Time Factors

2008
The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis.
    Free radical research, 2008, Volume: 42, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers, Tumor; Gene Expression Regulation; Lipid Peroxidation; Liver Neoplasms; Male; NF-kappa B; Oxidative Stress; Quercetin; Rats; Rats, Inbred F344; S-Adenosylmethionine; Signal Transduction

2008
Hepatoprotective effects of antioxidants in chronic hepatitis C.
    World journal of gastroenterology, 2010, Apr-21, Volume: 16, Issue:15

    Topics: Acetylcysteine; Antioxidants; Disease Progression; Fatty Liver; Fibrosis; Hepacivirus; Hepatitis C, Chronic; Humans; Liver; Nitric Oxide; Oxidative Stress; S-Adenosylmethionine; Virus Replication

2010
Oxidative stress is implicated in arsenic-induced neural tube defects in chick embryos.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:7

    Topics: Acetylcysteine; Animals; Arsenic; Chick Embryo; Epigenesis, Genetic; Female; Glutathione Peroxidase; Malondialdehyde; Neural Tube Defects; Oxidative Stress; Reactive Oxygen Species; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase

2011
Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.
    Parasitology, 2011, Volume: 138, Issue:9

    Topics: Acetylcysteine; Cell Culture Techniques; Cloning, Molecular; Cycloheximide; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Gene Expression; Immunoprecipitation; Kinetics; Leishmania donovani; Leishmaniasis, Visceral; Leupeptins; Methionine Adenosyltransferase; Oligopeptides; Plasmids; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Recombinant Proteins; S-Adenosylmethionine; Transfection; Ubiquitin

2011
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:8

    Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6

2012
Acute Hepatic Failure in a Dog after Xylitol Ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:2

    Topics: Acetylcysteine; Animals; Animals, Inbred Strains; Antidotes; Biomarkers; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Disseminated Intravascular Coagulation; Dogs; Hypoglycemia; Liver Failure, Acute; Male; S-Adenosylmethionine; Sweetening Agents; Treatment Outcome; Xylitol

2016
Alcoholic hepatitis: should we combine old drugs for better results?
    Hepatology international, 2016, Volume: 10, Issue:6

    Topics: Acetylcysteine; Antioxidants; Clinical Trials as Topic; Disease Management; Drug Therapy, Combination; Hepatitis, Alcoholic; Humans; Prednisolone; S-Adenosylmethionine; Treatment Outcome

2016
Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Calcium-Binding Proteins; Glutathione Disulfide; Heme Oxygenase-1; Homeostasis; Injections, Intraventricular; Lipids; Malondialdehyde; Melatonin; Microfilament Proteins; Microglia; Neurons; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; S-Adenosylmethionine; Synaptophysin; tau Proteins

2019
Arsenic inhibited cholesterol efflux of THP-1 macrophages via ROS-mediated ABCA1 hypermethylation.
    Toxicology, 2019, 08-01, Volume: 424

    Topics: Acetylcysteine; Antioxidants; Arsenic; ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; Macrophages; Methylation; Oxidative Stress; Reactive Oxygen Species; S-Adenosylmethionine

2019
Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
    Nature communications, 2021, 01-28, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Cell Differentiation; Cells, Cultured; Forkhead Box Protein O3; Free Radical Scavengers; Glycine N-Methyltransferase; HEK293 Cells; Herbicides; Humans; Interferon Type I; Lamins; Mice; Neural Stem Cells; Oxidative Stress; Paraquat; Protein Processing, Post-Translational; S-Adenosylmethionine; Signal Transduction

2021
Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Biomarkers; Carnitine; Chemical and Drug Induced Liver Injury; Drug Overdose; Humans; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mitochondria

2014
Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.
    Biomarkers in medicine, 2014, Volume: 8, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Age Factors; Alanine Transaminase; Biomarkers; Carnitine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Chromatography, High Pressure Liquid; Discriminant Analysis; Female; Humans; Least-Squares Analysis; Male; Mass Spectrometry; Metabolomics; Sex Factors

2014
Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency.
    The Journal of biological chemistry, 2015, Apr-17, Volume: 290, Issue:16

    Topics: Acetylcysteine; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Amino Acid Sequence; Carnitine; Congenital Bone Marrow Failure Syndromes; Cysteine; Dose-Response Relationship, Drug; Fatty Acids; Fibroblasts; Genetic Therapy; Humans; Kinetics; Lipid Metabolism, Inborn Errors; Mitochondrial Diseases; Molecular Sequence Data; Muscular Diseases; Mutation; Oxidation-Reduction; Primary Cell Culture; Skin

2015