s-8932 has been researched along with pyridine* in 1 studies
1 other study(ies) available for s-8932 and pyridine
Article | Year |
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Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.
Here, we report the synthesis, structure-activity relationship studies, enzyme inhibition, antiviral activity, and X-ray crystallographic studies of 5-chloropyridinyl indole carboxylate derivatives as a potent class of SARS-CoV-2 chymotrypsin-like protease inhibitors. Compound Topics: Adenosine Monophosphate; Alanine; Animals; Binding Sites; Chlorocebus aethiops; Coronavirus 3C Proteases; COVID-19; Crystallography, X-Ray; Humans; Indoles; Molecular Dynamics Simulation; Protease Inhibitors; Pyridines; SARS-CoV-2; Structure-Activity Relationship; Vero Cells | 2021 |