s 312 has been researched along with dihydropyridines in 16 studies
| Studies (s 312) | Trials (s 312) | Recent Studies (post-2010) (s 312) | Studies (dihydropyridines) | Trials (dihydropyridines) | Recent Studies (post-2010) (dihydropyridines) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 5,022 | 529 | 969 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 12 (75.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, M; Mihara, S | 1 |
| Kawabata, T; Nakamura, M; Shimizu, T | 1 |
| Nakajima, S; Ninomiya, M; Tani, T; Ueda, M | 1 |
| Adachi, I; Hiramatsu, Y; Kawakami, M; Masui, M; Mihara, S; Sakai, K; Ueda, M; Uno, O; Yamamori, T | 1 |
| Adachi, I; Eigyo, M; Inoue, Y; Ishibashi, C; Koyabu, K; Matsushita, A; Murata, S; Sakaguchi, I; Shiomi, T; Ueda, M | 1 |
| Adachi, I; Kawakami, M; Masui, M; Matsumura, S; Matsuura, E; Ninomiya, M; Ueda, M; Uno, O | 1 |
| Adachi, I; Nakajima, M; Ueda, M | 1 |
| Fujitomo, H; Hirohata, S; Kagawa, H; Kawakami, M; Masui, M; Matsumura, S; Matsuura, E; Shima, K; Ueda, M; Umeda, T | 1 |
| Adachi, I; Gemba, T; Ito, H; Kawakami, M; Masui, M; Matsunaga, K; Nakano, A; Ninomiya, M; Torii, M; Ueda, M | 1 |
| Hirano, K; Jizomoto, H; Kanaoka, E; Sugita, K | 1 |
| Dessy, C; Godfraind, T; Morel, N; Salomone, S | 1 |
| Fujitomo, H; Nishino, I; Ueno, K; Umeda, T | 1 |
| Gemba, T; Matsunaga, K; Ninomiya, M; Ueda, M | 1 |
| Mizojiri, K; Tanaka, H | 1 |
| Fujimoto, M; Hori, Y; Itoh, N; Okamura, N; Sakaeda, T; Sakaguchi, G; Ueda, K; Yagami, T | 1 |
| Aihua, Z; Amano, T; Matsubayashi, H; Sakai, N; Sasa, M; Seki, T; Serikawa, T | 1 |
16 other study(ies) available for s 312 and dihydropyridines
| Article | Year |
|---|---|
Effect of S-312, a new calcium channel blocker, on the 1,4-dihydropyridine binding sites in porcine basilar blood vessels and rat aortic smooth muscle cells.
Topics: Animals; Aorta; Basilar Artery; Binding Sites; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Muscle, Smooth, Vascular; Nicardipine; Nitrendipine; Oxadiazoles; Rats; Swine | 1991 |
Protective effect of a novel calcium blocker, S-312-d, on ischemic acute renal failure in rat.
Topics: Acute Kidney Injury; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ischemia; Kidney; Male; Rats; Rats, Inbred Strains | 1990 |
Effects of S-312, a new calcium antagonist, on the mechanical and electrophysiological responses of isolated cardiovascular preparations.
Topics: Animals; Arteries; Calcium Channel Blockers; Cecum; Dihydropyridines; Electrophysiology; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Sinoatrial Node; Vasodilation | 1989 |
Studies on dihydropyridines. III. Synthesis of 4,7-dihydrothieno [2,3-b]-pyridines with vasodilator and antihypertensive activities.
Topics: Animals; Antihypertensive Agents; Dihydropyridines; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilator Agents | 1988 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist, S-312-d. 5th communication: anticonvulsant effects in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Bemegride; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Electroshock; Female; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Seizures | 1994 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 1st communication: comparative studies on the cardiovascular effects of methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2,3- b]pyridine-5-carboxylate and its two ena
Topics: Animals; Antihypertensive Agents; Basilar Artery; Blood Pressure; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Dogs; Female; Guinea Pigs; Hemodynamics; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Inbred SHR; Regional Blood Flow; Stereoisomerism | 1993 |
Pharmacological studies on a new Dihydrothienopyridine calcium antagonist. 2nd communication: effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4- (3-nitrophenyl)thieno[2,3-b]pyridine-5-carboxylate on the 1,4-dihydropyridine binding sites in the bra
Topics: Animals; Binding, Competitive; Brain Chemistry; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Arteries; Dihydropyridines; Female; In Vitro Techniques; Isradipine; Macaca fascicularis; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1993 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 3rd communication: antihypertensive effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3-b] pyridine-5-carboxylate in hypertensive rats and dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Desoxycorticosterone; Dihydropyridines; Dogs; Female; Heart Rate; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renin | 1993 |
Pharmacological studies on a new dihydrothienopyridine calcium antagonist. 4th communication: prophylactic and therapeutic effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)thieno[2, 3- b]pyridine-5-carboxylate in stroke-prone spont
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Drinking; Eating; Heart Rate; Hypertension; Life Expectancy; Male; Nicardipine; Nimodipine; Organ Size; Rats; Rats, Inbred SHR; Sodium, Dietary | 1993 |
Gelatin-acacia microcapsules for trapping micro oil droplets containing lipophilic drugs and ready disintegration in the gastrointestinal tract.
Topics: Acacia; Animals; Biological Availability; Calcium Channel Blockers; Capsules; Chromatography, High Pressure Liquid; Digestive System; Dihydropyridines; Dogs; Drug Stability; Emulsions; Gelatin; Male; Oils; Powders; Probucol; Rats; Rats, Wistar; Solubility; Spectrophotometry, Ultraviolet | 1993 |
Activity of dihydrothienopyridine S312 enantiomers on L-type Ca2+ channels in isolated rat aorta and cerebral microvessels.
Topics: Animals; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Male; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Wistar; Stereoisomerism; Vasoconstriction; Vasodilator Agents | 1993 |
Determination of the enantiomers of a new 1,4-dihydropyridine calcium antagonist in dog plasma by achiral/chiral coupled high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Dogs; Electrochemistry; Stereoisomerism | 1993 |
Effects of a novel calcium antagonist, S-(+)-methyl-4,7-dihydro-3-isobutyl-6- methyl-4-(3-nitrophenyl)thieno[2,3-b]pyridine-5-carboxylate (S-312-d), on ischemic amino acid release and neuronal injury in stroke-prone spontaneously hypertensive rats.
Topics: Amino Acids; Animals; Antihypertensive Agents; Brain Ischemia; Calcium Channel Blockers; Cell Death; Dihydropyridines; Hemodynamics; Male; Neurons; Nimodipine; Rats; Rats, Inbred SHR | 1993 |
Drug-protein binding and blood-brain barrier permeability.
Topics: Animals; Benzodiazepines; Blood-Brain Barrier; Bridged Bicyclo Compounds; Caffeine; Calcium Channel Blockers; Diazepam; Dihydropyridines; Fatty Acids, Monounsaturated; Male; Microcirculation; Models, Biological; Nootropic Agents; Perfusion; Permeability; Pharmaceutical Preparations; Propranolol; Prosencephalon; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Serum Albumin, Bovine | 1999 |
Protective effects of a selective L-type voltage-sensitive calcium channel blocker, S-312-d, on neuronal cell death.
Topics: Amyloid beta-Peptides; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cell Survival; Cells, Cultured; Chromatin; Dihydropyridines; DNA Fragmentation; Drug Interactions; Microscopy; Neurons; Peptide Fragments; Phospholipases A; Protective Agents; Rats | 2004 |
Antiepileptic effects of single and repeated oral administrations of S-312-d, a novel calcium channel antagonist, on tonic convulsions in spontaneously epileptic rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Calcium Channel Blockers; Dihydropyridines; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Female; Male; Rats; Time Factors | 2004 |