Page last updated: 2024-09-03

s 14671 and buspirone

s 14671 has been researched along with buspirone in 4 studies

Compound Research Comparison

Studies
(s 14671)
Trials
(s 14671)
Recent Studies (post-2010)
(s 14671)
Studies
(buspirone)
Trials
(buspirone)
Recent Studies (post-2010) (buspirone)
10002,096351382

Protein Interaction Comparison

ProteinTaxonomys 14671 (IC50)buspirone (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.025
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)1.75
Angiotensin-converting enzyme Homo sapiens (human)0.024
D(2) dopamine receptorHomo sapiens (human)0.323
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)2.125
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)4.16
DRattus norvegicus (Norway rat)0.12
D(3) dopamine receptorRattus norvegicus (Norway rat)0.12
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0266
D(2) dopamine receptorBos taurus (cattle)4
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)4.16
Alpha-1D adrenergic receptorHomo sapiens (human)1.077
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.12
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.286
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.016
D(4) dopamine receptorRattus norvegicus (Norway rat)0.12
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)2.125
D(3) dopamine receptorHomo sapiens (human)0.044
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.75
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)4.16
D(2) dopamine receptorRattus norvegicus (Norway rat)0.2055
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.9811
Alpha-2A adrenergic receptorBos taurus (cattle)0.025
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.7
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.2666
Lysosomal alpha-glucosidaseBos taurus (cattle)0.03

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Bietti, G; Borsini, F; Ceci, A; Donetti, A1

Other Studies

4 other study(ies) available for s 14671 and buspirone

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
BIMT 17, a 5-HT1A receptor agonist/5-HT2A receptor antagonist, directly activates postsynaptic 5-HT inhibitory responses in the rat cerebral cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Benzimidazoles; Binding, Competitive; Buspirone; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Iontophoresis; Male; Microelectrodes; Neurons; Piperazines; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1995