Compounds > s-(3-deazaadenosyl)homocysteine
Page last updated: 2024-09-03

s-(3-deazaadenosyl)homocysteine and s-adenosylhomocysteine

s-(3-deazaadenosyl)homocysteine has been researched along with s-adenosylhomocysteine in 7 studies

Compound Research Comparison

Studies
(s-(3-deazaadenosyl)homocysteine)		Trials
(s-(3-deazaadenosyl)homocysteine)		Recent Studies (post-2010)
(s-(3-deazaadenosyl)homocysteine)		Studies
(s-adenosylhomocysteine)		Trials
(s-adenosylhomocysteine)		Recent Studies (post-2010) (s-adenosylhomocysteine)
7001,41220380

Protein Interaction Comparison

ProteinTaxonomys-(3-deazaadenosyl)homocysteine (IC50)s-adenosylhomocysteine (IC50)
Protein arginine N-methyltransferase 5Homo sapiens (human)0.4533
Histone-lysine N-methyltransferase SUV39H1Homo sapiens (human)1.2
Protein arginine N-methyltransferase 3Homo sapiens (human)0.9567
DNA (cytosine-5)-methyltransferase 1Homo sapiens (human)1.4212
WD repeat-containing protein 5Homo sapiens (human)0.724
Histone-lysine N-methyltransferase 2AHomo sapiens (human)1.512
Histone-lysine N-methyltransferase SETDB1Homo sapiens (human)2.2
Retinoblastoma-binding protein 5Homo sapiens (human)0.724
Histone-lysine N-methyltransferase EZH2Homo sapiens (human)1.9
N6-adenosine-methyltransferase catalytic subunitHomo sapiens (human)0.59
Histone-lysine N-methyltransferase KMT5CHomo sapiens (human)10
Histone-lysine N-methyltransferase, H3 lysine-79 specificHomo sapiens (human)0.39
Histone-lysine N-methyltransferase EZH1Homo sapiens (human)6.4
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)2.64
Protein arginine N-methyltransferase 1Homo sapiens (human)0.43
Methylosome protein 50Homo sapiens (human)0.58
Protein dpy-30 homologHomo sapiens (human)0.724
Histone-lysine N-methyltransferase EHMT1Homo sapiens (human)0.23
N-lysine methyltransferase SMYD2Homo sapiens (human)0.18
Protein arginine N-methyltransferase 7Homo sapiens (human)0.11
DNA (cytosine-5)-methyltransferase 3BHomo sapiens (human)0.3625
Set1/Ash2 histone methyltransferase complex subunit ASH2Homo sapiens (human)0.724
Non-structural protein 1 Dengue virus0.49

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Djurhuus, R; Svardal, A; Ueland, PM1
Backlund, PS; Cantoni, GL; Carotti, D1
Brown, ND; Chiang, PK; Miura, GA; Richard, MM; Stermer-Cox, MG1
Christoffersen, T; Døskeland, SO; Ogreid, D; Refsnes, M; Sand, TE; Schanche, JS; Ueland, PM1
Aksamit, RR; Cantoni, GL; Falk, W1
Chiang, PK; Montgomery, JA; Thomas, HJ; Thorpe, MC1
Creedon, KA; Rathod, PK; Wellems, TE1

Other Studies

7 other study(ies) available for s-(3-deazaadenosyl)homocysteine and s-adenosylhomocysteine

ArticleYear
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
    Molecular pharmacology, 1986, Volume: 30, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin

1986
Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis.
    European journal of biochemistry, 1986, Oct-15, Volume: 160, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cells, Cultured; Hydrolases; Methylation; Ribonucleosides; RNA, Messenger; S-Adenosylhomocysteine; Tubercidin

1986
Unexpected increase in catecholamines in adrenals of rats treated with 3-deazaadenosine.
    Biochemical and biophysical research communications, 1985, Mar-29, Volume: 127, Issue:3

    Topics: Adenosylhomocysteinase; Adrenal Glands; Animals; Epinephrine; Female; Hydrolases; Methylation; Norepinephrine; Rats; Rats, Inbred Strains; Ribonucleosides; S-Adenosylhomocysteine; Tubercidin

1985
Evidence against a requirement for phospholipid methylation in adenylate cyclase activation by hormones. Methyltransferase inhibitors do not impair cyclic AMP accumulation induced by glucagon or beta-adrenergic agents in rat hepatocytes.
    FEBS letters, 1982, Feb-22, Volume: 138, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Epinephrine; Glucagon; Homocysteine; Isomerism; Isoproterenol; Liver; Methyltransferases; Phospholipids; Rats; S-Adenosylhomocysteine; Tubercidin

1982
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line.
    The Journal of biological chemistry, 1982, Jan-25, Volume: 257, Issue:2

    Topics: Animals; Cell Line; Chemotaxis; Homocysteine; Isomerism; Kinetics; Macrophages; Mice; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin

1982
Synthesis of S-(3-deazaadenosyl)-L-homocysteine.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:12

    Topics: Chemical Phenomena; Chemistry; Homocysteine; Magnetic Resonance Spectroscopy; S-Adenosylhomocysteine

1981
Plasmodium falciparum S-adenosylhomocysteine hydrolase. cDNA identification, predicted protein sequence, and expression in Escherichia coli.
    The Journal of biological chemistry, 1994, Jun-10, Volume: 269, Issue:23

    Topics: Adenosylhomocysteinase; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Erythrocytes; Escherichia coli; Genes, Protozoan; Hydrolases; Molecular Sequence Data; Plasmodium falciparum; Recombinant Proteins; RNA, Messenger; S-Adenosylhomocysteine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transcription, Genetic; Tubercidin

1994