Compounds > s-(1,2-dichlorovinyl)cysteine
Page last updated: 2024-09-05

s-(1,2-dichlorovinyl)cysteine and probenecid

s-(1,2-dichlorovinyl)cysteine has been researched along with probenecid in 8 studies

Compound Research Comparison

Studies
(s-(1,2-dichlorovinyl)cysteine)		Trials
(s-(1,2-dichlorovinyl)cysteine)		Recent Studies (post-2010)
(s-(1,2-dichlorovinyl)cysteine)		Studies
(probenecid)		Trials
(probenecid)		Recent Studies (post-2010) (probenecid)
1541153,664292375

Protein Interaction Comparison

ProteinTaxonomys-(1,2-dichlorovinyl)cysteine (IC50)probenecid (IC50)
Solute carrier family 22 member 8Mus musculus (house mouse)3.02
Solute carrier family 22 member 6Homo sapiens (human)6.85
Solute carrier family 22 member 8Homo sapiens (human)6.965
Solute carrier family 22 member 8Rattus norvegicus (Norway rat)6.03

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anders, MW; Sharma, VK; Sheu, SS; Vamvakas, S1
Stevens, JL; Zhang, GH1
Brendel, K; Gandolfi, AJ; Stevens, JL; Wolfgang, GH1
Bakke, JE; Brandt, I; Darnerud, PO; Feil, VJ1
Anders, MW; Elfarra, AA; Jakobson, I1
Anders, MW; Lash, LH1
Dantzler, WH; Evans, KK; Wright, SH1
Dantzler, WH; Evans, KK; Groves, CE; North, J; Stevens, JL; Welborn, JR; Wright, SH1

Other Studies

8 other study(ies) available for s-(1,2-dichlorovinyl)cysteine and probenecid

ArticleYear
Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates.
    Molecular pharmacology, 1990, Volume: 38, Issue:4

    Topics: Animals; Calcium; Cell Line; Cysteine; Homeostasis; Homocysteine; Kidney; Mitochondria; Probenecid; Swine

1990
Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules.
    Toxicology and applied pharmacology, 1989, Volume: 100, Issue:1

    Topics: Acetylcysteine; Animals; Biological Transport; Biotransformation; Cysteine; Drug Interactions; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1989
N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism.
    Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2

    Topics: Acetylation; Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Dose-Response Relationship, Drug; Hydrocarbons, Halogenated; Kidney Cortex; Kidney Tubules, Proximal; p-Aminohippuric Acid; Potassium; Probenecid; Rabbits

1989
Dichlorovinyl cysteine (DCVC) in the mouse kidney: tissue-binding and toxicity after glutathione depletion and probenecid treatment.
    Archives of toxicology, 1989, Volume: 63, Issue:5

    Topics: Animals; Autoradiography; Cysteine; Female; Glutathione; Kidney; Kidney Diseases; Kidney Tubules; Mice; Mice, Inbred C57BL; Probenecid; Sulfhydryl Compounds

1989
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Blood Urea Nitrogen; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Glycosuria; Isoxazoles; Kidney; Liver; Lyases; Male; Mitochondria; Probenecid; Rats; Rats, Inbred F344; Subcellular Fractions

1986
Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Homocysteine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred F344; Sodium

1989
Kinetics of interactions of para-aminohippurate, probenecid, cysteine conjugates and N-acetyl cysteine conjugates with basolateral organic anion transporter in isolated rabbit proximal renal tubules.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Acetylcysteine; Animals; Anion Transport Proteins; Carrier Proteins; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Mercuric Chloride; p-Aminohippuric Acid; Probenecid; Rabbits

1995
Relation of cysteine conjugate nephrotoxicity to transport by the basolateral organic anion transport system in isolated S2 segments of rabbit proximal renal tubules.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Probenecid; Rabbits; Rubidium Radioisotopes

1998