s-(1,2-dichlorovinyl)cysteine has been researched along with aminooxyacetic acid in 17 studies
| Studies (s-(1,2-dichlorovinyl)cysteine) | Trials (s-(1,2-dichlorovinyl)cysteine) | Recent Studies (post-2010) (s-(1,2-dichlorovinyl)cysteine) | Studies (aminooxyacetic acid) | Trials (aminooxyacetic acid) | Recent Studies (post-2010) (aminooxyacetic acid) |
|---|---|---|---|---|---|
| 154 | 1 | 15 | 875 | 4 | 94 |
| Protein | Taxonomy | s-(1,2-dichlorovinyl)cysteine (IC50) | aminooxyacetic acid (IC50) |
|---|---|---|---|
| Cystathionine gamma-lyase | Homo sapiens (human) | 2.285 | |
| Cystathionine beta-synthase | Homo sapiens (human) | 5.275 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 9 (52.94) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q; Stevens, JL; Yu, K | 1 |
| Chen, Q; Holbrook, NJ; Stevens, JL; Yu, K | 1 |
| Chen, JC; Jones, TW; Stevens, JL; Trifillis, AL | 1 |
| Brendel, K; Gandolfi, AJ; Stevens, JL; Wolfgang, GH | 1 |
| Anders, MW; Elfarra, AA; Jakobson, I | 1 |
| Anders, MW; Lash, LH | 2 |
| Ayoubi, N; Robbins, JD; Stevens, JL | 1 |
| Hayden, P; Stevens, J; Taylor, G | 1 |
| Chen, Q; Jones, TW; Stevens, JL | 1 |
| Anders, MW; Finkelstein, MB; Patel, NJ | 1 |
| Jaspers, JJ; Maasdam, DH; Mulder, GJ; Nagelkerke, JF; Van de Water, B | 1 |
| Davis, JW; Petry, TW | 1 |
| Groves, CE; Hayden, PJ; Lock, EA; Schnellmann, RG | 1 |
| Anders, MW; Otieno, MA | 1 |
| Cummings, BS; Lash, LH | 1 |
| Anders, MW; Cai, J; Chen, Y; Jones, DP; Stevens, JL | 1 |
17 other study(ies) available for s-(1,2-dichlorovinyl)cysteine and aminooxyacetic acid
| Article | Year |
|---|---|
Regulation of the cellular stress response by reactive electrophiles. The role of covalent binding and cellular thiols in transcriptional activation of the 70-kilodalton heat shock protein gene by nephrotoxic cysteine conjugates.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cell Line; Cycloheximide; Cysteine; Dactinomycin; Dithiothreitol; Gene Expression Regulation; Heat-Shock Proteins; Hydrocarbons, Fluorinated; Kidney; Kinetics; Lipid Peroxidation; Molecular Weight; Protein Conformation; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1992 |
Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol.
Topics: Aminooxyacetic Acid; Calcium; Cations, Divalent; Cell Line; Cycloheximide; Cysteine; Dactinomycin; Dithiothreitol; DNA Damage; Drug Interactions; Kidney; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1992 |
Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
Topics: Adolescent; Adult; Aminooxyacetic Acid; Butadienes; Carbon-Sulfur Lyases; Cells, Cultured; Child; Cysteine; Dose-Response Relationship, Drug; Epithelial Cells; Female; Glutathione; Humans; Hydrocarbons, Fluorinated; Kidney Tubules, Proximal; Lyases; Male; Middle Aged; Structure-Activity Relationship | 1990 |
N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism.
Topics: Acetylation; Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Dose-Response Relationship, Drug; Hydrocarbons, Halogenated; Kidney Cortex; Kidney Tubules, Proximal; p-Aminohippuric Acid; Potassium; Probenecid; Rabbits | 1989 |
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
Topics: Aminooxyacetic Acid; Animals; Blood Urea Nitrogen; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Glycosuria; Isoxazoles; Kidney; Liver; Lyases; Male; Mitochondria; Probenecid; Rats; Rats, Inbred F344; Subcellular Fractions | 1986 |
Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.
Topics: Adenine Nucleotides; Aminooxyacetic Acid; Aminopeptidases; Animals; CD13 Antigens; Cell Survival; Cysteine; Dipeptides; Dose-Response Relationship, Drug; Glutathione; Glycylglycine; Isoxazoles; Kidney Tubules, Proximal; Male; Oxygen Consumption; Phenanthrolines; Rats; Rats, Inbred F344; Time Factors | 1986 |
Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
Topics: Aminooxyacetic Acid; Animals; Biological Transport; Cysteine; Homocysteine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred F344; Sodium | 1989 |
The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.
Topics: Aminooxyacetic Acid; Animals; Benzothiazoles; Cysteine; Cytosol; Keto Acids; Kidney; Lyases; Male; Methionine; Mitochondria; Rats; Rats, Inbred Strains; Transaminases | 1988 |
The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.
Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Carbon-Sulfur Lyases; Cell Line; Cell Survival; Cysteine; Glutathione; Isoxazoles; Kidney Tubules, Proximal; Lyases; Microscopy, Electron; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Swine | 1986 |
Early cellular events couple covalent binding of reactive metabolites to cell killing by nephrotoxic cysteine conjugates.
Topics: Aminooxyacetic Acid; Animals; Antioxidants; Calcium; Cell Death; Chelating Agents; Cysteine; Extracellular Space; Intracellular Membranes; Ionomycin; Kidney; Lipid Peroxides; LLC-PK1 Cells; Ruthenium Red; Swine | 1994 |
Metabolism of [14C]- and [35S]S-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat.
Topics: Aminooxyacetic Acid; Animals; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Inbred F344; Sulfates; Tissue Distribution | 1995 |
In vivo and in vitro detachment of proximal tubular cells and F-actin damage: consequences for renal function.
Topics: Actins; Aminooxyacetic Acid; Animals; Cell Death; Cell Membrane; Cells, Cultured; Cysteine; Cytoskeleton; Egtazic Acid; Kidney Medulla; Kidney Tubules, Proximal; Kinetics; Lipid Peroxidation; Male; Rats; Rats, Wistar; Time Factors | 1994 |
Inhibition of S-(1,2-dichlorovinyl)-L-cysteine-induced lipid peroxidation by antioxidants in rabbit renal cortical slices: dissociation of lipid peroxidation and toxicity.
Topics: Aminooxyacetic Acid; Animals; Antioxidants; Chromans; Cysteine; Deferoxamine; DNA; In Vitro Techniques; Kidney Cortex; Lipid Peroxidation; Male; Piperazines; Potassium; Pregnatrienes; Rabbits; Thiobarbituric Acid Reactive Substances | 1994 |
Differential cellular effects in the toxicity of haloalkene and haloalkane cysteine conjugates to rabbit renal proximal tubules.
Topics: Aminooxyacetic Acid; Animals; Biotransformation; Cell Death; Cysteine; Female; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; In Vitro Techniques; Kidney Tubules, Proximal; Lipid Peroxidation; Mitochondria; Oxygen Consumption; Rabbits; Sulfur Radioisotopes | 1993 |
Cysteine S-conjugates activate transcription factor NF-kappa B in cultured renal epithelial cells.
Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Antioxidants; Base Sequence; Cell Line; Cell Nucleus; Consensus Sequence; Cysteine; Cytosol; Epithelium; Genes, Reporter; Kidney; Luciferases; Macromolecular Substances; NF-kappa B; Oligodeoxyribonucleotides; Recombinant Fusion Proteins; Swine; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha | 1997 |
Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
Topics: Adult; Aged; Aminooxyacetic Acid; Chloral Hydrate; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Glutathione; Humans; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Metyrapone; Microsomes; Middle Aged; Trichloroethylene | 2000 |
Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.
Topics: Aminooxyacetic Acid; Animals; Apoptosis; Caspases; Cells, Cultured; Cysteine; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Intracellular Membranes; Kidney Tubules, Proximal; Membrane Potentials; Mitochondria; Models, Animal; Swine | 2001 |