Page last updated: 2024-09-05

s-(1,2-dichlorovinyl)cysteine and acetylcysteine

s-(1,2-dichlorovinyl)cysteine has been researched along with acetylcysteine in 12 studies

Compound Research Comparison

Studies
(s-(1,2-dichlorovinyl)cysteine)
Trials
(s-(1,2-dichlorovinyl)cysteine)
Recent Studies (post-2010)
(s-(1,2-dichlorovinyl)cysteine)
Studies
(acetylcysteine)
Trials
(acetylcysteine)
Recent Studies (post-2010) (acetylcysteine)
15411514,5801,0465,960

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boogaard, PJ; Commandeur, JN; Mulder, GJ; Vermeulen, NP1
Bakke, JE; Davison, KL1
Stevens, JL; Zhang, GH1
Anders, MW; Dekant, W; Elfarra, AA; Henschler, D; Vamvakas, S1
Hayden, P; Stevens, J; Taylor, G1
Dantzler, WH; Evans, KK; Wright, SH1
Bernauer, U; Birner, G; Dekant, W; Henschler, D1
Anders, MW; Otieno, MA1
Bernauer, U; Birner, G; Dekant, W; Werner, M1
Barshteyn, N; Elfarra, AA1
Elfarra, AA; Irving, RM1
Chiu, W; Furuya, S; Luo, YS; Rusyn, I1

Reviews

1 review(s) available for s-(1,2-dichlorovinyl)cysteine and acetylcysteine

ArticleYear
Role of reactive metabolites in the circulation in extrahepatic toxicity.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:9

    Topics: Acetylcysteine; Cysteine; Humans; Kidney; Liver; Trichloroethylene

2012

Other Studies

11 other study(ies) available for s-(1,2-dichlorovinyl)cysteine and acetylcysteine

ArticleYear
Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.
    Archives of toxicology, 1991, Volume: 65, Issue:5

    Topics: Acetylcysteine; Animals; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Stereoisomerism; Trichloroethylene

1991
Elimination of 14C by calves, pigs and rats renally perfused with radiolabelled dichlorovinyl or acetamide substrates.
    Toxicology letters, 1990, Volume: 53, Issue:1-2

    Topics: Acetanilides; Acetylation; Acetylcysteine; Animals; Carbon Radioisotopes; Cattle; Cysteine; Herbicides; Iodoacetamide; Kidney; Perfusion; Rats; Rats, Inbred Strains; Swine; Trichloroethylene

1990
Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules.
    Toxicology and applied pharmacology, 1989, Volume: 100, Issue:1

    Topics: Acetylcysteine; Animals; Biological Transport; Biotransformation; Cysteine; Drug Interactions; In Vitro Techniques; Kidney Tubules, Proximal; Male; Probenecid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1989
Mutagenicity of amino acid and glutathione S-conjugates in the Ames test.
    Mutation research, 1988, Volume: 206, Issue:1

    Topics: Acetylcysteine; Animals; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Homocysteine; Kidney; Liver; Lyases; Rats; Salmonella typhimurium; Structure-Activity Relationship

1988
The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.
    The Journal of biological chemistry, 1986, Mar-05, Volume: 261, Issue:7

    Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Carbon-Sulfur Lyases; Cell Line; Cell Survival; Cysteine; Glutathione; Isoxazoles; Kidney Tubules, Proximal; Lyases; Microscopy, Electron; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Swine

1986
Kinetics of interactions of para-aminohippurate, probenecid, cysteine conjugates and N-acetyl cysteine conjugates with basolateral organic anion transporter in isolated rabbit proximal renal tubules.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Acetylcysteine; Animals; Anion Transport Proteins; Carrier Proteins; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Mercuric Chloride; p-Aminohippuric Acid; Probenecid; Rabbits

1995
Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
    Archives of toxicology, 1996, Volume: 70, Issue:6

    Topics: Acetylcysteine; Administration, Inhalation; Adult; Aged; Animals; Biotransformation; Cysteine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Male; Middle Aged; Rats; Trichloroethylene

1996
Cysteine S-conjugates activate transcription factor NF-kappa B in cultured renal epithelial cells.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Antioxidants; Base Sequence; Cell Line; Cell Nucleus; Consensus Sequence; Cysteine; Cytosol; Epithelium; Genes, Reporter; Kidney; Luciferases; Macromolecular Substances; NF-kappa B; Oligodeoxyribonucleotides; Recombinant Fusion Proteins; Swine; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha

1997
Biotransformation, excretion and nephrotoxicity of haloalkene-derived cysteine S-conjugates.
    Archives of toxicology, 1997, Volume: 72, Issue:1

    Topics: Acetylation; Acetylcysteine; Animals; Biotransformation; Butadienes; Cysteine; Female; gamma-Glutamyltransferase; Kidney; Liver; Male; Necrosis; Rats; Rats, Wistar; Sex Factors

1997
Formation of three N-acetyl-L-cysteine monoadducts and one diadduct by the reaction of S-(1,2-dichlorovinyl)-L-cysteine sulfoxide with N-acetyl-L-cysteine at physiological conditions: chemical mechanisms and toxicological implications.
    Chemical research in toxicology, 2007, Volume: 20, Issue:10

    Topics: Acetylcysteine; Cross-Linking Reagents; Cysteine; Free Radical Scavengers; Kidney; Kidney Diseases; Sulfoxides

2007
Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.
    Journal of toxicology and environmental health. Part A, 2018, Volume: 81, Issue:1-3

    Topics: Acetylcysteine; Animals; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred Strains; Signal-To-Noise Ratio; Tissue Distribution; Trichloroethylene

2018