Page last updated: 2024-09-05

s-(1,2-dicarboxyethyl)cysteine and cysteine

s-(1,2-dicarboxyethyl)cysteine has been researched along with cysteine in 22 studies

Compound Research Comparison

Studies
(s-(1,2-dicarboxyethyl)cysteine)
Trials
(s-(1,2-dicarboxyethyl)cysteine)
Recent Studies (post-2010)
(s-(1,2-dicarboxyethyl)cysteine)
Studies
(cysteine)
Trials
(cysteine)
Recent Studies (post-2010) (cysteine)
2301340,13241811,457

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's3 (13.64)18.2507
2000's5 (22.73)29.6817
2010's8 (36.36)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Hirota, K; Ikeda, M; Ohmori, S; Tsuboi, S; Uda, N1
Abe, Y; Imoto, T; Ueda, T1
Funayama, S; Fushiya, S; Gu, QQ; Ishikawa, K; Nozoe, S1
Fushiya, S; Gu, Q; Nozoe, S1
Chen, G; Kodama, H; Lu, H; Manabe, M; Wang, C; Yamashita, K1
Alderson, NL; Alt, N; Baynes, JW; Blatnik, M; Carson, JA; Frizzell, N; Lyons, TJ; Nagai, R; Thorpe, SR; Walla, MD; Wang, Y1
Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD1
Baynes, JW; Blatnik, M; Frizzell, N; Thorpe, SR1
Baynes, JW; Carson, JA; Frizzell, N; Jepson, MJ; Nagai, R; Rajesh, M; Thorpe, SR1
Baynes, JW; Frizzell, N; Storey, KB; Thomas, SA1
Chen, YB; Frizzell, N; Garg, K; Karamurzin, Y; Nonaka, D; Reyes, C; Soslow, RA1
Frizzell, N; Garg, K; Joseph, NM; Rabban, JT; Solomon, DA; Zaloudek, C1
Beccuti, M; Cordero, F; Giraudo, MT; Miglio, G; Sabatino, AD; Veglia, E1
Agaimy, A; Berney, DM; Bonert, M; Brimo, F; Compérat, E; Frizzell, N; Gill, AJ; Hartmann, A; Hes, O; Hills, K; Husain, A; Kristiansen, G; Lüders, C; Maclean, F; Magi-Galluzzi, C; Martinek, P; Mehra, R; Nesi, G; Sibony, M; Srinivasan, B; Trpkov, K1
Buelow, B; Cohen, J; Frizzell, N; Garg, K; Joseph, NM; McCalmont, T; Nagymanyoki, Z1
Adam, J; Frizzell, N; Hartmann, A; Llamas-Velasco, M; Mentzel, T; Requena, L1
Cooper, AJL; Fiehn, O; Folz, J; Hanson, AD; McCarty, DR; Moraga Amador, D; Niehaus, TD1
Dutta, R; Fitzgerald, KA; Humphries, F; Ionete, C; Jiang, Z; Ketelut-Carneiro, N; Khalighinejad, F; Li, S; Muneeruddin, K; Nemmara, VV; Pesiridis, S; Shaffer, SA; Shmuel-Galia, L; Thompson, PR; Wang, B; Wilson, R; Yang, S1
Barbé, F; de-Torres, JP; Fernández, E; González, J; Gracia-Lavedan, E; Lecube, A; Pamplona, R; Torres, G1
Ellis, HR; Kammerer, B; Lagies, S; Matthews, A; Schleicher, E; Schönfelder, J; Stull, F; Teufel, R1
Katsuta, N; Nagai, M; Nagai, R; Sugawa, H; Takahashi, H1
Erickson, NA; Goethel, ME; Hillmann, KB; Niehaus, TD1

Other Studies

22 other study(ies) available for s-(1,2-dicarboxyethyl)cysteine and cysteine

ArticleYear
S-(1,2-dicarboxyethyl)glutathione and S-(1,2-dicarboxyethyl)L-cysteine in lens.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1984, Volume: 22, Issue:4

    Topics: Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Cysteine; Dinitrofluorobenzene; Dogs; Galactose; Glutathione; Guinea Pigs; Lens, Crystalline; Rabbits; Rats; Species Specificity; Tuna

1984
Reduction of disulfide bonds in proteins by 2-aminothiophenol under weakly acidic conditions.
    Journal of biochemistry, 1994, Volume: 115, Issue:1

    Topics: Aniline Compounds; Animals; Chickens; Cysteine; Disulfides; Hydrogen-Ion Concentration; Muramidase; Oxidation-Reduction; Proteins; Succinimides; Trypsin

1994
(2R), (1'R) and (2R), (1'S)-2-amino-3-(1,2-dicarboxyethylthio)propanoic acids from Amanita pantherina. Antagonists of N-methyl-D-aspartic acid (NMDA) receptors.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:3

    Topics: Amanita; Chromatography, High Pressure Liquid; Cysteine; Magnetic Resonance Spectroscopy; Receptors, N-Methyl-D-Aspartate

1993
[Absolute configuration of the diastereoisomer of 2-amino-3-(1,2-dicarboxyethylthio) propanoic acid from Amanita pantherina].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:1

    Topics: Amanita; Animals; Animals, Newborn; Cysteine; Molecular Conformation; Motor Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stereoisomerism

1998
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:11

    Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2002
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.
    Archives of biochemistry and biophysics, 2006, Jun-01, Volume: 450, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Citric Acid Cycle; Collagen; Cysteine; Diabetes Mellitus, Experimental; Female; Fumarates; Glycation End Products, Advanced; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Insulin; Insulin, Long-Acting; Insulin, Regular, Human; Muscle Proteins; Protein Processing, Post-Translational; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Human; Skin; Succinic Acid

2006
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds

2007
Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.
    Diabetes, 2008, Volume: 57, Issue:1

    Topics: Animals; Chromatography, Liquid; Cysteine; Diabetes Mellitus, Experimental; Fumarates; Gas Chromatography-Mass Spectrometry; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Kinetics; Mass Spectrometry; Mitochondria; Muscle, Skeletal; Peptide Fragments; Rats

2008
Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.
    The Journal of biological chemistry, 2009, Sep-18, Volume: 284, Issue:38

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Adipose Tissue; Animals; Biomarkers; Citric Acid Cycle; Cysteine; Diabetes Mellitus; Mice; Mitochondria; Protein Multimerization; Protein Processing, Post-Translational

2009
Tissue distribution of S-(2-succino)cysteine (2SC), a biomarker of mitochondrial stress in obesity and diabetes.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:2

    Topics: Adipocytes; Adipose Tissue; Animals; Biomarkers; Blotting, Western; Cells, Cultured; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Mice; Mice, Obese; Mitochondria; Obesity; Rats; Sciuridae; Succinates

2012
Uterine smooth muscle tumors with features suggesting fumarate hydratase aberration: detailed morphologic analysis and correlation with S-(2-succino)-cysteine immunohistochemistry.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2014, Volume: 27, Issue:7

    Topics: Adult; Cysteine; Female; Fumarate Hydratase; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Immunohistochemistry; Middle Aged; Smooth Muscle Tumor; Uterine Neoplasms

2014
Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.
    The American journal of surgical pathology, 2015, Volume: 39, Issue:11

    Topics: Adult; Age Factors; Biomarkers, Tumor; Biopsy; Cysteine; DNA Mutational Analysis; Female; Fumarate Hydratase; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Leiomyomatosis; Mutation; Neoplastic Syndromes, Hereditary; Phenotype; Predictive Value of Tests; Prognosis; Skin Neoplasms; Uterine Neoplasms; Young Adult

2015
A computational analysis of S-(2-succino)cysteine sites in proteins.
    Biochimica et biophysica acta, 2016, Volume: 1864, Issue:2

    Topics: Amino Acids; Computational Biology; Cysteine; Fumarates; Humans; Models, Theoretical; Molecular Conformation; Protein Processing, Post-Translational; Proteins; Proteome; Sequence Analysis, Protein; Succinates

2016
Fumarate Hydratase-deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome.
    The American journal of surgical pathology, 2016, Volume: 40, Issue:7

    Topics: Adult; Aged; Carcinoma, Renal Cell; Cysteine; Female; Fumarate Hydratase; Germ-Line Mutation; Humans; Immunohistochemistry; Kidney Neoplasms; Leiomyomatosis; Male; Metabolism, Inborn Errors; Middle Aged; Muscle Hypotonia; Neoplastic Syndromes, Hereditary; Psychomotor Disorders; Skin Neoplasms; Tissue Array Analysis; Uterine Neoplasms; Young Adult

2016
Immunohistochemistry for 2-Succinocysteine (2SC) and Fumarate Hydratase (FH) in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome).
    The American journal of surgical pathology, 2016, Volume: 40, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cysteine; DNA Mutational Analysis; Female; Fumarate Hydratase; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Immunohistochemistry; Leiomyomatosis; Male; Middle Aged; Neoplastic Syndromes, Hereditary; Polymerase Chain Reaction; Skin Neoplasms; Uterine Neoplasms

2016
Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.
    The American Journal of dermatopathology, 2016, Volume: 38, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cysteine; DNA Mutational Analysis; Down-Regulation; Early Detection of Cancer; Female; Fumarate Hydratase; Humans; Immunohistochemistry; Leiomyomatosis; Male; Middle Aged; Mutation; Neoplastic Syndromes, Hereditary; Predictive Value of Tests; Protein Processing, Post-Translational; Reproducibility of Results; Skin Neoplasms; Uterine Neoplasms

2016
Identification of a metabolic disposal route for the oncometabolite
    The Journal of biological chemistry, 2018, 05-25, Volume: 293, Issue:21

    Topics: Acetylation; Bacillus subtilis; Cysteine; Fumarates; Metabolomics; Neoplasms; Operon; Signal Transduction

2018
Succination inactivates gasdermin D and blocks pyroptosis.
    Science (New York, N.Y.), 2020, 09-25, Volume: 369, Issue:6511

    Topics: Animals; Caspases; Citric Acid Cycle; Cysteine; Dimethyl Fumarate; Encephalomyelitis, Autoimmune, Experimental; Familial Mediterranean Fever; Female; HEK293 Cells; Humans; Inflammasomes; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Multiple Sclerosis; Phosphate-Binding Proteins; Protein Processing, Post-Translational; Pyroptosis

2020
Protein succination as a potential surrogate biomarker of airway obstruction. The ilervas project.
    Respiratory medicine, 2020, Volume: 172

    Topics: Airway Obstruction; Biomarkers; Case-Control Studies; Citric Acid Cycle; Cysteine; Female; Glycation End Products, Advanced; Humans; Hypoxia; Inflammation; Male; Middle Aged; Mitochondria; Oxidative Stress; Severity of Illness Index

2020
Bacterial flavoprotein monooxygenase YxeK salvages toxic S-(2-succino)-adducts via oxygenolytic C-S bond cleavage.
    The FEBS journal, 2022, Volume: 289, Issue:3

    Topics: Acetylation; Bacillus subtilis; Cysteine; Flavins; Flavoproteins; Fumarates; Kinetics; Mixed Function Oxygenases; Models, Chemical; Mutagenesis, Site-Directed; Operon; Substrate Specificity; Sulfhydryl Compounds

2022
Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging.
    Amino acids, 2022, Volume: 54, Issue:4

    Topics: Aging; Animals; Chromatography, Liquid; Cysteine; Fumarates; Glycation End Products, Advanced; Male; Mice; Mice, Inbred C57BL; Tandem Mass Spectrometry

2022
Identification of a S-(2-succino)cysteine breakdown pathway that uses a novel S-(2-succino) lyase.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:12

    Topics: Acetylcysteine; Cysteine; Fumarates; Lyases; Sulfhydryl Compounds

2022