s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid has been researched along with zileuton in 6 studies
| Studies (s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid) | Trials (s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid) | Recent Studies (post-2010) (s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid) | Studies (zileuton) | Trials (zileuton) | Recent Studies (post-2010) (zileuton) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 551 | 64 | 193 |
| Protein | Taxonomy | s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid (IC50) | zileuton (IC50) |
|---|---|---|---|
| Prostaglandin E synthase | Homo sapiens (human) | 0.6 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.4782 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.9656 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | 0.4 | |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | 0.58 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.591 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Mus musculus (house mouse) | 0.19 | |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 0.42 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belfast, MT; Carlson, RP; Glaser, KB; Hartman, DA; Ochalski, SJ; Walter, TL | 1 |
| Howell, RE; Jenkins, LP; Rubin, EB; Sickels, BD; Weichman, BM; Woeppel, SL | 1 |
| Berkenkopf, JW; Carlson, RP; Grimes, D; Kreft, AF; Marinari, LR; Musser, JH; Sturm, RJ; Weichman, BM | 1 |
| Berkenkopf, JW; Grimes, D; Heaslip, RJ; Ilsemann, BA; Sickels, BD; Weichman, BM | 1 |
| Carlson, RP; Gray, WB; Grimes, D; Hartman, DA; Howell, RE; Jenkins, LP; Kreft, AF; Kubrak, D | 1 |
| Carlson, R; Glaser, K; Hartman, D; Kreft, A; Lock, Y; Tomchek, L; Weichman, B | 1 |
6 other study(ies) available for s(alpha)-methyl-6-(2-quinolinylmethoxy)-2-naphthaleneacetic acid and zileuton
| Article | Year |
|---|---|
Inhibition of endotoxin-induced hypothermia and serum TNF-alpha levels in CD-1 mice by various pharmacological agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endotoxins; Hydroxyurea; Hypothermia; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Mice; Naphthaleneacetic Acids; Quinolines; Shock, Septic; Tromethamine; Tumor Necrosis Factor-alpha | 1993 |
Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs.
Topics: Acetophenones; Animals; Antigens; Bronchoconstriction; Eosinophilia; Guinea Pigs; Hydroxyurea; Indoles; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Male; Naphthaleneacetic Acids; Quinolines; Tetrazoles | 1994 |
WY-50,295 tromethamine, a novel, orally active 5-lipoxygenase inhibitor: biochemical characterization and antiallergic activity.
Topics: Administration, Oral; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Asthma; Female; Guinea Pigs; Humans; Hydroxyurea; Indoles; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Naphthaleneacetic Acids; Prostaglandin-Endoperoxide Synthases; Quinolines; Rabbits; Rats; Rats, Wistar | 1993 |
Anti-leukotriene effects of WY-50,295 tromethamine in isolated guinea pig pulmonary tissues.
Topics: Acetophenones; Animals; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Muscle Contraction; Muscle, Smooth; Naphthaleneacetic Acids; Quinolines; SRS-A; Tetrazoles; Trachea | 1993 |
Pulmonary pharmacology of WAY-126299A: a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist.
Topics: Acetamides; Anesthesia; Animals; Benzothiazoles; Bronchoconstriction; Guinea Pigs; Humans; Hydroxyurea; In Vitro Techniques; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Naphthaleneacetic Acids; Quinolines; Respiration, Artificial; Thiazoles | 1995 |
WY-50295 tromethamine: a 5-lipoxygenase inhibitor without activity in human whole blood.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Eicosanoids; Guinea Pigs; Humans; Hydroxyurea; Indoles; Leukocytes; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Naphthaleneacetic Acids; Neutrophils; Quinolines; Rats; Serum Albumin | 1999 |