ryanodine has been researched along with formamide* in 1 studies
1 other study(ies) available for ryanodine and formamide
| Article | Year |
|---|---|
Reversed effect of caffeine on non-contractile and contractile Ca2+ mobilization operated by acetylcholine receptor in mouse diaphragm muscle.
Caffeine effects on contractile and acetylcholine receptor-related non-contractile Ca2+ mobilization were investigated in phrenic nerve-diaphragm muscles of mice with neostigmine. Caffeine enhanced at 0.25-5 mM, and decreased at 7-20 mM the total amount of contractile Ca(2+)-aequorin luminescence (Ca2+ transients), but only decreased at 2-10 mM non-contractile Ca2+ transients. Pretreatment with formamide (2 M for 30 min) abolished contractile Ca2+ transients, but did not affect non-contractile ones. These results suggest that non-contractile Ca2+ mobilization is not due to direct Ca2+ release from sarcoplasmic reticulum, but due to direct modulation by nicotinic acetylcholine receptor. Topics: Animals; Caffeine; Calcium; Diaphragm; Formamides; Male; Mice; Muscle Contraction; Muscles; Neostigmine; Receptors, Cholinergic; Ryanodine | 1991 |