ryanodine and cathinone

The core myopathies are a group of congenital myopathies with variable clinical expression - ranging from early-onset skeletal-muscle weakness to later-onset disease of variable severity - that are identified by characteristic 'core-like' lesions in myofibers and the presence of hypothonia and slowly or rather non-progressive muscle weakness. The genetic causes are diverse; central core disease is most often caused by mutations in ryanodine receptor 1 (

Topics: Alkaloids; Animals; Connectin; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Genetic Association Studies; Genetic Variation; HEK293 Cells; Humans; Male; Mice; Mice, Transgenic; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Structural, Congenital; Myopathy, Central Core; Ophthalmoplegia; Protein Kinases; Ryanodine; Ryanodine Receptor Calcium Release Channel; Selenoproteins