rx 821002 has been researched along with sibutramine in 3 studies
| Studies (rx 821002) | Trials (rx 821002) | Recent Studies (post-2010) (rx 821002) | Studies (sibutramine) | Trials (sibutramine) | Recent Studies (post-2010) (sibutramine) |
|---|---|---|---|---|---|
| 317 | 0 | 45 | 967 | 218 | 204 |
| Protein | Taxonomy | rx 821002 (IC50) | sibutramine (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 5.665 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 2.39 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 5.665 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.085 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.632 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bearham, MC; Heal, DJ; Hutchins, LJ; Jackson, HC; Mazurkiewicz, SE; Needham, AM | 1 |
| Heal, DJ; Hughes, ZA; Stanford, SC; Wortley, KE | 1 |
| Heal, DJ; Stanford, SC; Wortley, KE | 1 |
3 other study(ies) available for rx 821002 and sibutramine
| Article | Year |
|---|---|
Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat.
Topics: Adrenergic Uptake Inhibitors; Animals; Cyclobutanes; Eating; Idazoxan; Male; Metoprolol; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors | 1997 |
Comparison of changes in the extracellular concentration of noradrenaline in rat frontal cortex induced by sibutramine or d-amphetamine: modulation by alpha2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Cerebral Cortex; Cyclobutanes; Dextroamphetamine; Idazoxan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1999 |
Modulation of sibutramine-induced increases in extracellular noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Cyclobutanes; Dialysis; Frontal Lobe; Hypothalamus; Idazoxan; Imidazoles; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1999 |