rx 821002 has been researched along with medetomidine in 6 studies
| Studies (rx 821002) | Trials (rx 821002) | Recent Studies (post-2010) (rx 821002) | Studies (medetomidine) | Trials (medetomidine) | Recent Studies (post-2010) (medetomidine) |
|---|---|---|---|---|---|
| 317 | 0 | 45 | 1,335 | 296 | 444 |
| Protein | Taxonomy | rx 821002 (IC50) | medetomidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 3.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Durcan, MJ; Linnoila, M; Morgan, PF; Van Etten, ML | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Barsh, GS; Haapalinna, A; Kobilka, BK; Kulatunga, M; Leino, T; Link, RE; Macdonald, E; Pelto-Huikko, M; Sallinen, J; Scheinin, M; Sjöholm, B; Viitamaa, T | 1 |
| Bol, CJ; Danhof, M; IJzerman, AP; Mandema, JW | 1 |
| Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM | 1 |
| Audinot, V; Chaput, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Richard, N; Touzard, M; Verrièle, L | 1 |
6 other study(ies) available for rx 821002 and medetomidine
| Article | Year |
|---|---|
Covariation of alpha 2-adrenoceptor density and function following irreversible antagonism with EEDQ.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Dioxanes; Drug Interactions; Exploratory Behavior; Hypnotics and Sedatives; Idazoxan; Imidazoles; Male; Medetomidine; Mice; Motor Activity; Quinolines; Radioligand Assay; Receptors, Adrenergic, alpha-2 | 1994 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Biogenic Monoamines; Body Temperature; Brain Chemistry; Idazoxan; Imidazoles; Medetomidine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Receptors, Adrenergic, alpha-2; RNA, Messenger | 1997 |
Determination of dexmedetomidine in rat plasma by a sensitive [3H]clonidine radioreceptor assay.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Clonidine; Idazoxan; Imidazoles; Magnesium; Male; Manganese; Medetomidine; Membranes; Radioligand Assay; Rats; Reproducibility of Results; Retina; Sensitivity and Specificity; Tritium | 1997 |
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin | 1998 |
Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; CHO Cells; Cricetinae; Guanfacine; Humans; Idazoxan; Imidazoles; Ligands; Medetomidine; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Yohimbine | 1998 |