rx 821002 has been researched along with guanabenz in 6 studies
| Studies (rx 821002) | Trials (rx 821002) | Recent Studies (post-2010) (rx 821002) | Studies (guanabenz) | Trials (guanabenz) | Recent Studies (post-2010) (guanabenz) |
|---|---|---|---|---|---|
| 317 | 0 | 45 | 446 | 42 | 96 |
| Protein | Taxonomy | rx 821002 (IC50) | guanabenz (IC50) |
|---|---|---|---|
| trace amine-associated receptor 1 | Homo sapiens (human) | 1.173 | |
| Solute carrier family 22 member 1 | Homo sapiens (human) | 4.85 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.204 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.041 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.149 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.106 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 2.068 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 1.787 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.472 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.392 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.204 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 2.068 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.097 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uhlén, S; Wikberg, JE | 1 |
| García-Sevilla, JA; Sastre, M | 1 |
| Anderson, WP; Evans, RG | 1 |
| Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM | 1 |
| Coles, SK; Dick, TE; Ernsberger, P | 1 |
| Dambrova, M; Oliver, DW; Tiger, G; Uhlén, S; Wikberg, JE | 1 |
6 other study(ies) available for rx 821002 and guanabenz
| Article | Year |
|---|---|
Delineation of three pharmacological subtypes of alpha 2-adrenoceptor in the rat kidney.
Topics: Animals; Binding, Competitive; Computer Simulation; Dioxanes; Guanabenz; Idazoxan; In Vitro Techniques; Kidney; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Alpha 2-adrenoceptor subtypes identified by [3H]RX821002 binding in the human brain: the agonist guanoxabenz does not discriminate different forms of the predominant alpha 2A subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Brain; Dioxanes; Edetic Acid; Female; Guanabenz; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Piperazines; Receptors, Adrenergic, alpha; Sodium Chloride; Tritium | 1994 |
Renal effects of infusion of rilmenidine and guanabenz in conscious dogs: contribution of peripheral and central nervous system alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autonomic Nerve Block; Binding Sites; Blood Pressure; Central Nervous System; Consciousness; Dioxanes; Dogs; Dose-Response Relationship, Drug; Ganglia, Autonomic; Guanabenz; Heart Rate; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Male; Oxazoles; Peripheral Nervous System; Receptors, Adrenergic, alpha-2; Receptors, Drug; Renal Circulation; Rilmenidine | 1995 |
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin | 1998 |
Post-hypoxic frequency decline does not depend on alpha2-adrenergic receptors in the adult rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cerebral Ventricles; Guanabenz; Idazoxan; Infusions, Parenteral; Male; Rats; Rats, Sprague-Dawley; Respiratory Mechanics | 1998 |
Characterization of the enzymatic activity for biphasic competition by guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) at alpha2-adrenoceptors. I. Description of an enzymatic activity in spleen membranes.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Guanabenz; Idazoxan; Magnesium; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spleen; Xanthine Oxidase | 1998 |