Compounds > rx 821002
Page last updated: 2024-09-02

rx 821002 and colforsin

rx 821002 has been researched along with colforsin in 10 studies

Compound Research Comparison

Studies
(rx 821002)		Trials
(rx 821002)		Recent Studies (post-2010)
(rx 821002)		Studies
(colforsin)		Trials
(colforsin)		Recent Studies (post-2010) (colforsin)
31704513,460461,298

Protein Interaction Comparison

ProteinTaxonomyrx 821002 (IC50)colforsin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)1.729
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.041
Adenylate cyclase type 1Homo sapiens (human)0.0955

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's7 (70.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dieudonne, MN; Giudicelli, Y; Pecquery, R1
Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D1
Lafontan, M; Langin, D; Paris, H; Stillings, MR1
Bouloumie, A; Galitzky, J; Lafontan, M; Langin, D; Remaury, A; Tavernier, G; Valet, P1
Lee, A; Lynch, KR; Rosin, DL; Talley, E1
Goldstein, I; Huang, YH; Moreland, RB; Traish, AM1
Correze, C; Dib, K; el Jamali, A; Lambert, B; Wrisez, F1
Farley, JT; Klimek, V; Ordway, GA; Zhang, W; Zhu, MY1
Akerman, KE; Jansson, CC; Kukkonen, JP1
Akerman, KE; Holmqvist, T; Kukkonen, JP; Näsman, J1

Other Studies

10 other study(ies) available for rx 821002 and colforsin

ArticleYear
Characteristics of the alpha 2/beta-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites.
    European journal of biochemistry, 1992, Apr-15, Volume: 205, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cricetinae; Dioxanes; Epididymis; Epinephrine; GTP-Binding Proteins; Idazoxan; Isoproterenol; Kinetics; Lipolysis; Macromolecular Substances; Male; Mesocricetus; Organ Specificity; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Theophylline

1992
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1990
[3H]RX821002: a new tool for the identification of alpha 2A-adrenoceptors.
    European journal of pharmacology, 1989, Aug-11, Volume: 167, Issue:1

    Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Catecholamines; Cell Membrane; Colforsin; Cyclic AMP; Dioxanes; Dioxins; Humans; Idazoxan; Kinetics; Radioligand Assay; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine

1989
Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Base Sequence; Brimonidine Tartrate; Bucladesine; Catecholamines; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dioxanes; DNA Primers; Epididymis; Gene Expression; Idazoxan; Isoproterenol; Lipase; Lipolysis; Male; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger; Skin

1995
Characterization of alpha 2A-adrenergic receptors in GT1 neurosecretory cells.
    Neuroendocrinology, 1995, Volume: 62, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blotting, Northern; Cell Line; Colforsin; Dioxanes; Idazoxan; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurons; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha

1995
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
    Receptors & signal transduction, 1997, Volume: 7, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine

1997
Sodium saccharin inhibits adenylyl cyclase activity in non-taste cells.
    Cellular signalling, 1997, Volume: 9, Issue:6

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adrenergic alpha-Agonists; Animals; Astrocytes; Brimonidine Tartrate; Carcinogens; Cell Fractionation; Cell Membrane; Cerebral Cortex; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Idazoxan; Male; Pertussis Toxin; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Wistar; Saccharin; Signal Transduction; Swine; Taste; Thyroid Gland; Virulence Factors, Bordetella

1997
alpha2C adrenoceptors inhibit adenylyl cyclase in mouse striatum: potential activation by dopamine.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Cell Line; Colforsin; Corpus Striatum; Crosses, Genetic; Cyclic AMP; Dopamine; Enzyme Activation; Homozygote; Idazoxan; In Vitro Techniques; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Reserpine; Transfection

1999
Agonist trafficking of G(i/o)-mediated alpha(2A)-adrenoceptor responses in HEL 92.1.7 cells.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Adrenergic Agonists; Adrenergic Antagonists; Biological Transport; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Idazoxan; Pertussis Toxin; Propranolol; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella; Yohimbine

2001
Different roles for Gi and Go proteins in modulation of adenylyl cyclase type-2 activity.
    Journal of neurochemistry, 2002, Volume: 83, Issue:6

    Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Humans; Idazoxan; Pertussis Toxin; Protein Kinase C; Receptors, Adrenergic, alpha-2; Signal Transduction; Spodoptera; Tetradecanoylphorbol Acetate

2002