rx 821002 has been researched along with cocaine in 6 studies
| Studies (rx 821002) | Trials (rx 821002) | Recent Studies (post-2010) (rx 821002) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 317 | 0 | 45 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | rx 821002 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Booze, RM; Mactutus, CF; Silvers, JM; Snow, DM; Strupp, BJ; Wallace, DR | 1 |
| Achterberg, EJ; Schoffelmeer, AN; Schrama, L; Siviy, SM; Trezza, V; Vanderschuren, LJ | 1 |
| Beveridge, TJ; Nader, MA; Porrino, LJ; Smith, HR | 1 |
| Aalderink, M; Achterberg, EJ; Driel, NV; Houwing, DJ; Servadio, M; Trezza, V; van Kerkhof, LW; van Swieten, MM; Vanderschuren, LJ | 1 |
| Dobrzański, G; Kwiatkowska, K; Pradel, K; Przewłocki, R; Solecki, WB; Szklarczyk, K | 1 |
| Asaoka, Y; Kamii, H; Kaneda, K; Minami, M; Shinohara, F | 1 |
6 other study(ies) available for rx 821002 and cocaine
| Article | Year |
|---|---|
Prenatal cocaine exposure alters alpha2 receptor expression in adolescent rats.
Topics: Adrenergic alpha-Antagonists; Age Factors; Animals; Autoradiography; Body Weight; Cocaine; Dopamine Uptake Inhibitors; Female; Idazoxan; Male; Pregnancy; Prenatal Exposure Delayed Effects; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sexual Maturation; Tritium | 2006 |
Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Flupenthixol; Idazoxan; Male; Motor Activity; Piperazines; Play and Playthings; Propylamines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Behavior | 2014 |
Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Autoradiography; Brain; Cocaine; Cocaine-Related Disorders; Fluoxetine; Idazoxan; Macaca mulatta; Male; Neural Pathways; Norepinephrine Plasma Membrane Transport Proteins; Receptors, Adrenergic, alpha-2; Reinforcement Schedule; Self Administration | 2016 |
Contrasting Roles of Dopamine and Noradrenaline in the Motivational Properties of Social Play Behavior in Rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Cocaine; Conditioning, Operant; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Idazoxan; Male; Methylphenidate; Motivation; Neuropsychological Tests; Norepinephrine; Piperazines; Random Allocation; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Dopamine; Social Behavior | 2016 |
Noradrenergic signaling in the VTA modulates cocaine craving.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Craving; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Idazoxan; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area | 2018 |
Stress augments the rewarding memory of cocaine via the activation of brainstem-reward circuitry.
Topics: Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Brain Stem; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Idazoxan; Male; Memory; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Restraint, Physical; Reward; Stress, Psychological; Tegmentum Mesencephali; Timolol | 2019 |