rwj-54428 and quinupristin

rwj-54428 has been researched along with quinupristin* in 1 studies

Other Studies

1 other study(ies) available for rwj-54428 and quinupristin

Article	Year
In vitro activity of a new cephalosporin, RWJ-54428, against streptococci, enterococci and staphylococci, including glycopeptide-intermediate Staphylococcus aureus. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:5 The need for new antimicrobial agents with activity against Gram-positive organisms has become increasingly important because of emerging resistance. We compared the activity of a new b-lactam antimicrobial agent, RWJ-54428 (MC-02 479), with representatives of other classes of antimicrobial agents against 76 Staphylococcus aureus (including four glycopeptide- intermediate strains), 50 coagulase-negative staphylococci, 20 Enterococcus faecalis, 20 Enterococcus faecium, 10 Enterococcus gallinarum/Enterococcus casseliflavus, 54 Streptococcus pneumoniae and 22 viridans streptococcal isolates. The MIC(90) of RWJ-54,428 was < or = 2 mg/L for all groups of bacteria tested except E. faecium. The activity against four strains of glycopeptide-intermediate S. aureus was similar to that for other methicillin-resistant S. aureus isolates (range 0.5-2.0 mg/L). Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Staphylococcus aureus; Streptococcus; Virginiamycin	2002

Article

Year

In vitro activity of a new cephalosporin, RWJ-54428, against streptococci, enterococci and staphylococci, including glycopeptide-intermediate Staphylococcus aureus.

The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:5

The need for new antimicrobial agents with activity against Gram-positive organisms has become increasingly important because of emerging resistance. We compared the activity of a new b-lactam antimicrobial agent, RWJ-54428 (MC-02 479), with representatives of other classes of antimicrobial agents against 76 Staphylococcus aureus (including four glycopeptide- intermediate strains), 50 coagulase-negative staphylococci, 20 Enterococcus faecalis, 20 Enterococcus faecium, 10 Enterococcus gallinarum/Enterococcus casseliflavus, 54 Streptococcus pneumoniae and 22 viridans streptococcal isolates. The MIC(90) of RWJ-54,428 was < or = 2 mg/L for all groups of bacteria tested except E. faecium. The activity against four strains of glycopeptide-intermediate S. aureus was similar to that for other methicillin-resistant S. aureus isolates (range 0.5-2.0 mg/L).

Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Staphylococcus aureus; Streptococcus; Virginiamycin

2002