Page last updated: 2024-09-05

rwj 22108 and nitrendipine

rwj 22108 has been researched along with nitrendipine in 2 studies

Compound Research Comparison

Studies
(rwj 22108)
Trials
(rwj 22108)
Recent Studies (post-2010)
(rwj 22108)
Studies
(nitrendipine)
Trials
(nitrendipine)
Recent Studies (post-2010) (nitrendipine)
5002,17037883

Protein Interaction Comparison

ProteinTaxonomyrwj 22108 (IC50)nitrendipine (IC50)
G-protein coupled receptor 55Homo sapiens (human)1.4652
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.0152
Cytochrome P450 2C9 Homo sapiens (human)0.3
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0013
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.0013
Cytochrome P450 2C19Homo sapiens (human)3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.0152
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.0013
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)10
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.0152
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0152
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)1.85

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, WC; Mockoviak, S; Moore, JB1
Dodd, JH; Gray-Nunez, Y; Kirchner, T; Loughney, D; Miller, WC; Mockoviak, S; Moore, JB; Ritchie, DM; Schwender, CF1

Other Studies

2 other study(ies) available for rwj 22108 and nitrendipine

ArticleYear
RWJ-22108--a novel airway tissue--selective calcium channel blocker.
    Agents and actions, 1993, Volume: 40, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardium; Nitrendipine; Potassium Chloride; Pyridines; Rabbits; Radioligand Assay; Respiratory System; Trachea

1993
Design and discovery of RWJ 22108--a novel bronchoselective calcium channel blocker.
    Drug design and discovery, 1998, Volume: 15, Issue:3

    Topics: Animals; Anti-Asthmatic Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Bronchi; Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Dogs; Drug Design; Female; In Vitro Techniques; Models, Molecular; Nitrendipine; Organ Specificity; Pyridines; Rabbits; Structure-Activity Relationship; Trachea

1998