Page last updated: 2024-08-24

rutecarpine and evodiamine

rutecarpine has been researched along with evodiamine in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (6.67)	18.2507
2000's	20 (33.33)	29.6817
2010's	31 (51.67)	24.3611
2020's	5 (8.33)	2.80

Authors

Authors	Studies
Dai, Y; Kogure, Y; Noguchi, K; Wang, S; Yamamoto, S; Zhang, W	1
Kano, Y; Komatsu, K; Qine, Z	1
Chen, CF; Chiou, WF; Liao, JF	1
Momma, N; Ohsawa, K; Ueda, J; Yamauchi, Y; Yoshie, F	1
Iinuma, M; Kubo, M; Matsuda, H; Tanaka, T; Wu, JX	1
Hoshikuma, K; Kamiya, T; Kobayashi, Y; Nakano, Y; Yokoo, Y	1
Chen, CF; Chen, TL; Guengerich, FP; Jan, WC; Lin, LC; Ueng, YF	1
Chen, CF; Chen, KT; Ko, HC; Ueng, YF; Wang, JJ	1
Fei, XF; Ikejima, T; Li, TJ; Minami, M; Tashiro, S; Wang, BX; Xing, DJ	1
Wang, YL; Wei, LX; Xu, YC; Zhou, YX	1
Liang, JY; Wang, QZ	1
Aggarwal, BB; Kobayashi, Y; Takada, Y	1
Benvenuti, S; Melegari, M; Pellati, F; Yoshizaki, F	1
Cai, XF; Choi, YH; Kim, HP; Kim, YS; Lee, JJ; Shin, EM	1
Li, C; Liao, Y; Liu, H; Liu, Y; Wen, D	1
Chen, CF; Chen, CM; Chen, KT; Ko, HC; Su, JP; Wang, GJ	1
Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH	1
Bae, EA; Cai, XF; Kim, DH; Lee, JJ; Shin, YW	1
Gao, HM; Hong, YM; Wang, JY; Wang, WH; Wang, ZM	1
Teng, J; Wang, Y; Xu, W; Yang, XW	1
Heo, SK; Noh, EK; Park, SD; Yi, HS; Yun, HJ	1
Chao, HL; Wang, PS; Wang, SW; Yu, PL	1
Du, M; Jin, R; Kang, C; Li, J; Li, M; Liu, S	1
Feng, W; Gao, H; Gong, M; Song, Y; Wang, W; Wang, Z; Yan, L; Zhang, Q; Zhu, J	1
Kang, C; Li, M; Liu, S; Tong, H; Wang, Y; Yin, W; Zhou, Z	1
Chen, MC; Chi, CW; Ho, LL; Kan, SF; Lee, CH; Lin, LC; Pu, HF; Wang, PS; Wang, SW; Yu, CH	1
Chen, JJ; Hwang, TL; Kuo, YH; Wang, TY; Wu, JB	1
Chang, Y; Guo, F; Jiang, H; Liu, B; Wang, Q	1
Chen, Y; Huang, Z; Liu, Y; Wu, Y; Yi, J	1
Li, J; Liu, Y; Ma, X	1
Feng, NP; Liu, Y; Shi, F; Wang, Z; Zhang, SJ; Zhang, YT; Zhao, JH; Zhong, YZ	1
Chen, F; Ding, J; He, L; Li, Y; Peng, J; Xu, S; Zhang, J	1
Cai, J; Li, W; Lin, C; Lin, G; Ma, J; Pan, J; Pan, X; Wang, X	1
Bubenyák, M	1
Bao, T; Dong, Y; Li, Y; Weng, X; Yang, Q; Zhang, Y; Zhu, X	1
Hu, CQ; Li, F; Yang, XW	1
Chen, F; Ding, JS; Li, D; Li, S	1
Feng, NP; Huang, ZB; Liu, Y; Wang, Z; Zhang, SJ; Zhang, YT; Zhao, JH	1
Chen, Y; Huang, Z; Liu, Y; Tang, X; Yi, J; Zhao, J	1
Ivanova, B; Spiteller, M	1
Jin, HW; Qian, P; Yang, XW	1
Liu, L; Moore, DJ; Roongta, V; Wen, B	1
Fu, Q; Jin, Y; Li, K; Li, Z; Liang, T	1
Domonkos, C; Fitos, I; Visy, J; Zsila, F	1
Cai, Q; Li, W; Shi, S; Wang, Q; Wei, J; Wei, R; Zhang, Y; Zhao, W	1
Missler, SR; Rebhun, JF; Roloff, SJ; Velliquette, RA	1
Cheng, Y; Li, X; Wang, X; Xue, H; Yue, Y; Zhang, W	1
Chen, B; Hu, H; Huang, M; Lei, J; Li, Y; Lu, J; Wang, Z; Xie, W; Yu, L; Zeng, K; Zeng, S	1
Gong, M; He, R; He, S; Lu, X; Pan, X; Wu, Y; Xu, Y	1
Gao, B; Guo, H; Liu, D; Ren, H; Santos, HA; Xu, F; You, M; Zhang, H; Zhang, X	1
Feng, NP; He, ZH; Li, Z; Xia, Q; Zhang, HY; Zhang, K; Zhang, YT; Zhao, JH	1
Bisson, WH; Gonzalez, FJ; Krausz, KW; Sun, D; Xie, C; Yagai, T; Yan, T; Yang, X; Zhang, L; Zhang, Y; Zheng, Y	1
Aisa, HA; Cao, JG; Huang, GZ; Liu, FZ; Nie, LF; Wang, SS; Xiamuxi, H	1
Li, JJ; Tian, KM; Xu, SW	1
Chen, Z; Liu, Y; Mao, Z; Zhou, W	1
Chen, Z; Zhang, B	1
Ge, J; Li, X; Liu, R; Sun, R; Zhang, J; Zheng, Q	1
Chen, P; Jia, J; Jia, Y; Li, H; Wang, X; Wang, Y; Xiu, R; Xue, Y; Zhang, G; Zhang, X; Zhao, Z	1
Chu, QR; Du, SS; He, YH; Li, HX; Liu, YQ; Tang, C; Wang, JR; Wu, TL; Yang, CJ; Zhang, ZJ	1
Guo, H; Jin, R; Liu, J; Tang, Y; Wang, Y; Yan, H; Zhou, J	1

Reviews

2 review(s) available for rutecarpine and evodiamine

Article	Year
Rutaecarpine: A promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu). Pharmacological research, 2019, Volume: 141 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Evodia; Humans; Hypolipidemic Agents; Indole Alkaloids; Platelet Aggregation Inhibitors; Quinazolines; Vasodilator Agents	2019
Evodiamine and rutaecarpine from Tetradium ruticarpum in the treatment of liver diseases. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 68 Topics: Animals; Evodia; Humans; Indole Alkaloids; Liver Diseases; Plants, Medicinal; Quinazolines	2020

Other Studies

58 other study(ies) available for rutecarpine and evodiamine

Article	Year
Partial Activation and Inhibition of TRPV1 Channels by Evodiamine and Rutaecarpine, Two Major Components of the Fruits of Evodia rutaecarpa. Journal of natural products, 2016, 05-27, Volume: 79, Issue:5 Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Evodia; Fruit; HEK293 Cells; Humans; Indole Alkaloids; Molecular Structure; Quinazolines; TRPV Cation Channels	2016
[On the evaluation of the preparation of Chinese medicinal prescriptions. VI. The changes of the alkaloid contents by processing of Evodia fruit]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1991, Volume: 111, Issue:1 Topics: Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Indole Alkaloids; Plant Extracts; Quinazolines; Quinolones; Taste	1991
Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. Journal of natural products, 1996, Volume: 59, Issue:4 Topics: Alkaloids; Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indole Alkaloids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Vasodilator Agents	1996
[A simultaneous determination of evodiamine and rutaecarpine in oriental pharmaceutical decoctions containing Evodia fruit by ion-pair high-performance liquid chromatography]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1996, Volume: 116, Issue:1 Topics: Alkaloids; Cardiotonic Agents; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Indole Alkaloids; Plant Extracts; Quinazolines	1996
Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components. Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:3 Topics: Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; China; Chromatography, High Pressure Liquid; Indole Alkaloids; Limonins; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Triterpenes; Vasodilator Agents	1997
The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors. Planta medica, 2001, Volume: 67, Issue:3 Topics: Alkaloids; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Dose-Response Relationship, Drug; Fruit; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Indole Alkaloids; Male; Myocardial Contraction; Plant Extracts; Platelet Aggregation Inhibitors; Purinergic Antagonists; Pyridoxal Phosphate; Quinazolines; Receptors, Drug; Rosales; Ruthenium Red; Stimulation, Chemical	2001
The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:3 Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Indole Alkaloids; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Plant Extracts; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Theophylline	2002
Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice. Life sciences, 2002, Aug-02, Volume: 71, Issue:11 Topics: Alkaloids; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drugs, Chinese Herbal; Glucuronosyltransferase; Glutathione Transferase; Humans; Indole Alkaloids; Liver; Male; Methanol; Mice; Mice, Inbred C57BL; Oxazines; Plant Extracts; Plants, Medicinal; Quinazolines; Rutaceae	2002
Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells. Cancer science, 2003, Volume: 94, Issue:1 Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Division; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Evodia; Fibrosarcoma; Fluorouracil; Furans; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HeLa Cells; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Melanoma; Mice; Mitochondria; Molecular Structure; Neoplasm Proteins; Oligopeptides; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Rats; Rats, Inbred BUF; Sarcoma 180; Tumor Cells, Cultured	2003
[Determination of evodiamine and rutaecarpine in Evodia rutaecarpa (Juss.) Benth after compatibility with Coptis chinensis Franch]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:12 Topics: Alkaloids; Coptis; Drug Combinations; Drugs, Chinese Herbal; Evodia; Indole Alkaloids; Plant Extracts; Plants, Medicinal; Quinazolines	2001
[Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth]. Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:8 Topics: Alkaloids; Carbolines; Evodia; Fruit; Indole Alkaloids; Molecular Structure; Plant Extracts; Plants, Medicinal; Quinazolines	2004
Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17 Topics: Active Transport, Cell Nucleus; Alkaloids; Annexin A5; Apoptosis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Collagen; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Enzyme Activation; Evodia; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; I-kappa B Kinase; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Indole Alkaloids; Inflammation; Laminin; MAP Kinase Signaling System; Microscopy, Fluorescence; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Protein Serine-Threonine Kinases; Proteoglycans; Quinazolines; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation	2005
Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species. Journal of separation science, 2006, Volume: 29, Issue:5 Topics: Chromatography, High Pressure Liquid; Evodia; Fruit; Indole Alkaloids; Medicine, Chinese Traditional; Molecular Structure; Phenethylamines; Plant Extracts; Plants, Medicinal; Polyethylene Glycols; Psychotropic Drugs; Quinazolines; Reproducibility of Results; Solvents; Stereoisomerism; Synephrine; Vasoconstrictor Agents; Vasodilator Agents	2006
Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms. Archives of pharmacal research, 2006, Volume: 29, Issue:4 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Leukotriene C4; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Mice; NF-kappa B; Plant Extracts; Quinazolines	2006
Determination of evodiamine and rutecarpine in human serum by liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry, 2006, Volume: 385, Issue:6 Topics: Chromatography, Liquid; Evodia; Humans; Indole Alkaloids; Mass Spectrometry; Plant Extracts; Quinazolines; Reproducibility of Results; Tandem Mass Spectrometry	2006
Chemical and biological comparisons on Evodia with two related species of different locations and conditions. Journal of ethnopharmacology, 2006, Nov-24, Volume: 108, Issue:2 Topics: Alkaloids; Animals; Aorta; China; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Evodia; Female; Fruit; In Vitro Techniques; Indole Alkaloids; Male; Methanol; Molecular Structure; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Species Specificity; Synephrine; Taiwan	2006
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells. European journal of pharmacology, 2007, Jan-26, Volume: 555, Issue:2-3 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate	2007
In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1 Topics: Alkaloids; Animals; Anti-Allergic Agents; Behavior, Animal; Cell Degranulation; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Plant Extracts; Pruritus; Quinazolines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2007
[Methodological studies on equivalent relationship between granule for clinical prescription and clinical decoction of fructus evodiae]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:12 Topics: Alkaloids; Animals; Drugs, Chinese Herbal; Evodia; Female; Fruit; Hot Temperature; Indole Alkaloids; Male; Mice; Mice, Inbred ICR; Pain Threshold; Plant Extracts; Plants, Medicinal; Quinazolines; Technology, Pharmaceutical	2007
The permeability and the efflux of alkaloids of the Evodiae fructus in the Caco-2 model. Phytotherapy research : PTR, 2009, Volume: 23, Issue:1 Topics: Alkaloids; Biological Transport, Active; Caco-2 Cells; Chromatography, High Pressure Liquid; Evodia; Humans; Indole Alkaloids; Intestinal Absorption; Permeability; Plant Extracts; Quinazolines	2009
Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation. Journal of cellular biochemistry, 2009, May-01, Volume: 107, Issue:1 Topics: Cell Line; Cell Movement; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Immunoblotting; Indole Alkaloids; Intercellular Adhesion Molecule-1; Monocytes; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Plant Extracts; Protein Serine-Threonine Kinases; Quinazolines; Reactive Oxygen Species; Receptors, CCR2; Tumor Necrosis Factor Ligand Superfamily Member 14	2009
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. Journal of cellular biochemistry, 2009, Oct-01, Volume: 108, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Cyclic AMP; Desoxycorticosterone; Drugs, Chinese Herbal; Evodia; Hydroxycholesterols; Indole Alkaloids; Male; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents; Zona Fasciculata; Zona Reticularis	2009
[Study on vitro release and transdermal behaviors of Yulian cataplasm]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:8 Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Indole Alkaloids; Mice; Plant Extracts; Quinazolines; Skin; Skin Absorption	2009
[Assay of evodin, evodiamine and rutaecarpine in Fructus Evodiae by QAMS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:21 Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Evodia; Furans; Heterocyclic Compounds, 4 or More Rings; Indole Alkaloids; Plant Extracts; Quinazolines	2009
[Determination of evodiamine and rutaecarpine of compound Wuzhuyu cataplasm in plasma by SPE-HPLC: application to its pharmacokinetics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:22 Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Indole Alkaloids; Male; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Solid Phase Extraction	2009
Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO. Journal of cellular biochemistry, 2010, Aug-15, Volume: 110, Issue:6 Topics: Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Evodia; G2 Phase; Humans; In Situ Nick-End Labeling; Indole Alkaloids; Plant Extracts; Poly(ADP-ribose) Polymerases; Quinazolines; Thyroid Neoplasms; Time Factors	2010
A new quinolone and other constituents from the fruits of Tetradium ruticarpum: effects on neutrophil pro-inflammatory responses. Chemistry & biodiversity, 2010, Volume: 7, Issue:7 Topics: Anti-Inflammatory Agents; Evodia; Fruit; Humans; Indole Alkaloids; Molecular Structure; Neutrophils; Pancreatic Elastase; Plant Extracts; Quinazolines; Quinolines; Quinolones; Superoxides	2010
Optimization of extraction of evodiamine and rutaecarpine from fruit of Evodia rutaecarpa using modified supercritical CO(2). Journal of chromatography. A, 2010, Dec-10, Volume: 1217, Issue:50 Topics: Algorithms; Analysis of Variance; Carbon Dioxide; Chemical Fractionation; Chromatography, High Pressure Liquid; Evodia; Fruit; Indole Alkaloids; Methanol; Plant Extracts; Pressure; Quinazolines; Temperature; Time Factors	2010
[Optimization of a HPLC determination method for Evodia rutaecarpa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:4 Topics: Chromatography, High Pressure Liquid; Evodia; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines	2011
[Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:7 Topics: Alkaloids; Capsules; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Linear Models; Quality Control; Quinazolines; Reproducibility of Results	2011
Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion. International journal of nanomedicine, 2011, Volume: 6 Topics: Administration, Cutaneous; Animals; Emulsions; Indole Alkaloids; Male; Microdialysis; Microscopy, Electron, Transmission; Pharmaceutical Vehicles; Quinazolines; Rats; Rats, Sprague-Dawley; Skin Absorption	2011
Pharmacokinetic comparisons of rutaecarpine and evodiamine after oral administration of Wu-Chu-Yu extracts with different purities to rats. Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2 Topics: Administration, Oral; Alkaloids; Animals; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Evodia; Indole Alkaloids; Intestinal Absorption; Male; Plant Extracts; Quinazolines; Quinolines; Rats; Rats, Sprague-Dawley; Reference Standards	2012
Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics. Die Pharmazie, 2011, Volume: 66, Issue:12 Topics: Animals; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Half-Life; Indicators and Reagents; Indole Alkaloids; Injections, Intravenous; Male; Quinazolines; Rabbits; Reference Standards; Reproducibility of Results; Solutions; Spectrometry, Mass, Electrospray Ionization	2011
[Synthesis, physicochemical and pharmacological properties of pentacyclic alkaloid-analogues]. Acta pharmaceutica Hungarica, 2011, Volume: 81, Issue:4 Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Survival; Drugs, Chinese Herbal; Evodia; HeLa Cells; Humans; Indole Alkaloids; Piroxicam; Plant Extracts; Quinazolines; Therapeutic Equivalency	2011
[Studies on pharmacokinetics of evodiamine and rutaecarpine in rats plasma after oral administration extracts of euodiae fructus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:24 Topics: Administration, Oral; Animals; Evodia; Indole Alkaloids; Male; Plant Extracts; Quinazolines; Rats; Rats, Wistar	2011
Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction. Journal of Asian natural products research, 2012, Volume: 14, Issue:4 Topics: Administration, Oral; Alkaloids; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Indole Alkaloids; Male; Molecular Structure; Quinazolines; Rats	2012
Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo. Fitoterapia, 2012, Volume: 83, Issue:5 Topics: Administration, Cutaneous; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Female; Indole Alkaloids; Male; Mice; Oleic Acid; Pain; Plant Extracts; Quinazolines; Sesquiterpenes; Skin; Swine	2012
In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion. International journal of nanomedicine, 2012, Volume: 7 Topics: Animals; Emulsions; Fibroblasts; Indole Alkaloids; Mice; Microscopy, Confocal; Nanoparticles; NIH 3T3 Cells; Particle Size; Quinazolines; Rhodamines	2012
Simultaneous determination of six bioactive compounds in Evodiae Fructus by high-performance liquid chromatography with diode array detection. Journal of chromatographic science, 2014, Volume: 52, Issue:2 Topics: Chromatography, High Pressure Liquid; Drug Stability; Evodia; Fruit; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines; Reproducibility of Results; Triterpenes	2014
Evodiamine and rutaecarpine alkaloids as highly selective transient receptor potential vanilloid 1 agonists. International journal of biological macromolecules, 2014, Volume: 65 Topics: Animals; Humans; Indole Alkaloids; Models, Molecular; Protein Conformation; Quinazolines; Rabbits; Rats; Substrate Specificity; TRPV Cation Channels	2014
New limonoids from Coptidis Rhizoma-Euodiae Fructus couple. Journal of Asian natural products research, 2014, Volume: 16, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Evodia; Fruit; Humans; Indole Alkaloids; Limonins; Molecular Structure; Quinazolines; Rhizome	2014
Metabolic activation of the indoloquinazoline alkaloids evodiamine and rutaecarpine by human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:6 Topics: Activation, Metabolic; Cytochrome P-450 CYP3A; Humans; Hydrogenation; Indole Alkaloids; Microsomes, Liver; Plant Extracts; Quinazolines	2014
[Fast analysis of indole alkaloids from Evodiae fructus by supercritical fluid chromatography]. Se pu = Chinese journal of chromatography, 2014, Volume: 32, Issue:5 Topics: Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Evodia; Indole Alkaloids; Quinazolines	2014
Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine. Physical chemistry chemical physics : PCCP, 2014, Nov-07, Volume: 16, Issue:41 Topics: Binding Sites; Circular Dichroism; Humans; Indole Alkaloids; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Quinazolines; Serum Albumin; Spectrophotometry, Ultraviolet; Stereoisomerism	2014
Toxicity of Evodiae fructus on rat liver mitochondria: the role of oxidative stress and mitochondrial permeability transition. Molecules (Basel, Switzerland), 2014, Dec-16, Volume: 19, Issue:12 Topics: Adenosine Triphosphate; Animals; Cytochromes c; Evodia; Furans; Glutathione; Heterocyclic Compounds, 4 or More Rings; Indole Alkaloids; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxidative Stress; Permeability; Plant Extracts; Quinazolines; Rats; Superoxide Dismutase	2014
Identification of evodiamine as the bioactive compound in evodia (Evodia rutaecarpa Benth.) fruit extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia, 2015, Volume: 101 Topics: Animals; CHO Cells; Chromans; Chromatography, High Pressure Liquid; Cricetulus; Evodia; Fruit; Hep G2 Cells; Humans; Indole Alkaloids; Mass Spectrometry; Molecular Structure; Plant Extracts; PPAR gamma; Quinazolines; Thiazolidinediones; Troglitazone	2015
Rutaecarpine and evodiamine selected as β1-AR inhibitor candidates using β1-AR/CMC-offline-UPLC/MS prevent cardiac ischemia-reperfusion injury via energy modulation. Journal of pharmaceutical and biomedical analysis, 2015, Nov-10, Volume: 115 Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Cell Membrane; Cell Survival; CHO Cells; Chromatography, High Pressure Liquid; Cricetulus; Energy Metabolism; Evodia; Indole Alkaloids; Male; Mass Spectrometry; Myocardial Reperfusion Injury; Quinazolines; Rats, Wistar; Receptors, Adrenergic, beta-1	2015
Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor. Biochimica et biophysica acta, 2016, Volume: 1859, Issue:9 Topics: Alkaloids; Animals; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Evodia; Forkhead Box Protein O1; Gene Expression Regulation; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Hypoglycemic Agents; Indole Alkaloids; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoenolpyruvate Carboxykinase (ATP); Primary Cell Culture; Quinazolines; Receptors, Cytoplasmic and Nuclear; Signal Transduction	2016
Optimization of combinations of ginsenoside-Rg1, ginsenoside-Rb1, evodiamine and rutaecarpine for effective therapy of mouse migraine. Journal of natural medicines, 2016, Volume: 70, Issue:2 Topics: Animals; Dopamine; Drug Combinations; Drugs, Chinese Herbal; Ginsenosides; Indole Alkaloids; Medicine, Chinese Traditional; Mice, Inbred ICR; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Phytotherapy; Quinazolines; Serotonin	2016
Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models. Molecules (Basel, Switzerland), 2016, Jul-21, Volume: 21, Issue:7 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Quinazolines; Spectrum Analysis; Spheroids, Cellular; Tumor Cells, Cultured	2016
Co-delivery of evodiamine and rutaecarpine in a microemulsion-based hyaluronic acid hydrogel for enhanced analgesic effects on mouse pain models. International journal of pharmaceutics, 2017, Aug-07, Volume: 528, Issue:1-2 Topics: Analgesics; Animals; Dinoprostone; Drug Carriers; Emulsions; Guinea Pigs; Hyaluronic Acid; Hydrogels; Indole Alkaloids; Interleukin-6; Mice; Pain; Quinazolines; Skin Absorption; Tumor Necrosis Factor-alpha	2017
Structure-Activity Relationships of the Main Bioactive Constituents of Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:7 Topics: Alkaloids; Animals; Bile Acids and Salts; Cell Line, Tumor; Drugs, Chinese Herbal; Evodia; Genes, Reporter; Hep G2 Cells; Hepatocytes; Homeostasis; Humans; Indole Alkaloids; Liver; Male; Mice; Mice, Inbred C57BL; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Structure-Activity Relationship; Up-Regulation	2018
Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3- Journal of Asian natural products research, 2020, Volume: 22, Issue:1 Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Indole Alkaloids; Lung Neoplasms; Molecular Structure; Pyrimidinones; Quinazolines; Structure-Activity Relationship	2020
Analysis of Evodiae Fructus by capillary electrochromatography-mass spectrometry with methyl-vinylimidazole functionalized organic polymer monolilth as stationary phases. Journal of chromatography. A, 2019, Sep-27, Volume: 1602 Topics: Acetonitriles; Ammonia; Calibration; Capillary Electrochromatography; Drugs, Chinese Herbal; Electrolytes; Evodia; Fruit; Hydrogen-Ion Concentration; Imidazoles; Indole Alkaloids; Limit of Detection; Limonins; Mass Spectrometry; Polymers; Quinazolines; Reference Standards; Reproducibility of Results	2019
Screening of cathepsin B inhibitors in traditional Chinese medicine by capillary electrophoresis with immobilized enzyme microreactor. Journal of pharmaceutical and biomedical analysis, 2019, Nov-30, Volume: 176 Topics: Amaryllidaceae Alkaloids; Cathepsin B; Drug Discovery; Drugs, Chinese Herbal; Electrophoresis, Capillary; Enzymes, Immobilized; Feasibility Studies; Indole Alkaloids; Indolizines; Kaempferols; Molecular Docking Simulation; Quinazolines; Theophylline	2019
Identification of evodiamine and rutecarpine as novel TMEM16A inhibitors and their inhibitory effects on peristalsis in isolated Guinea-pig ileum. European journal of pharmacology, 2021, Oct-05, Volume: 908 Topics: Animals; Cricetulus; Guinea Pigs; Indole Alkaloids; Interstitial Cells of Cajal; Peristalsis; Quinazolines	2021
Design, synthesis and biological evaluation of novel evodiamine and rutaecarpine derivatives against phytopathogenic fungi. European journal of medicinal chemistry, 2022, Jan-05, Volume: 227 Topics: Antifungal Agents; Ascomycota; Botrytis; Dose-Response Relationship, Drug; Drug Design; Fusarium; Indole Alkaloids; Microbial Sensitivity Tests; Molecular Structure; Quinazolines; Rhizoctonia; Structure-Activity Relationship	2022
Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study. International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19 Topics: Antineoplastic Agents; Evodia; Indole Alkaloids; Ligands; Molecular Docking Simulation; Quinazolines; Quinazolinones	2022