rutecarpine has been researched along with evodiamine in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (6.67) | 18.2507 |
2000's | 20 (33.33) | 29.6817 |
2010's | 31 (51.67) | 24.3611 |
2020's | 5 (8.33) | 2.80 |
Authors | Studies |
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Dai, Y; Kogure, Y; Noguchi, K; Wang, S; Yamamoto, S; Zhang, W | 1 |
Kano, Y; Komatsu, K; Qine, Z | 1 |
Chen, CF; Chiou, WF; Liao, JF | 1 |
Momma, N; Ohsawa, K; Ueda, J; Yamauchi, Y; Yoshie, F | 1 |
Iinuma, M; Kubo, M; Matsuda, H; Tanaka, T; Wu, JX | 1 |
Hoshikuma, K; Kamiya, T; Kobayashi, Y; Nakano, Y; Yokoo, Y | 1 |
Chen, CF; Chen, TL; Guengerich, FP; Jan, WC; Lin, LC; Ueng, YF | 1 |
Chen, CF; Chen, KT; Ko, HC; Ueng, YF; Wang, JJ | 1 |
Fei, XF; Ikejima, T; Li, TJ; Minami, M; Tashiro, S; Wang, BX; Xing, DJ | 1 |
Wang, YL; Wei, LX; Xu, YC; Zhou, YX | 1 |
Liang, JY; Wang, QZ | 1 |
Aggarwal, BB; Kobayashi, Y; Takada, Y | 1 |
Benvenuti, S; Melegari, M; Pellati, F; Yoshizaki, F | 1 |
Cai, XF; Choi, YH; Kim, HP; Kim, YS; Lee, JJ; Shin, EM | 1 |
Li, C; Liao, Y; Liu, H; Liu, Y; Wen, D | 1 |
Chen, CF; Chen, CM; Chen, KT; Ko, HC; Su, JP; Wang, GJ | 1 |
Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH | 1 |
Bae, EA; Cai, XF; Kim, DH; Lee, JJ; Shin, YW | 1 |
Gao, HM; Hong, YM; Wang, JY; Wang, WH; Wang, ZM | 1 |
Teng, J; Wang, Y; Xu, W; Yang, XW | 1 |
Heo, SK; Noh, EK; Park, SD; Yi, HS; Yun, HJ | 1 |
Chao, HL; Wang, PS; Wang, SW; Yu, PL | 1 |
Du, M; Jin, R; Kang, C; Li, J; Li, M; Liu, S | 1 |
Feng, W; Gao, H; Gong, M; Song, Y; Wang, W; Wang, Z; Yan, L; Zhang, Q; Zhu, J | 1 |
Kang, C; Li, M; Liu, S; Tong, H; Wang, Y; Yin, W; Zhou, Z | 1 |
Chen, MC; Chi, CW; Ho, LL; Kan, SF; Lee, CH; Lin, LC; Pu, HF; Wang, PS; Wang, SW; Yu, CH | 1 |
Chen, JJ; Hwang, TL; Kuo, YH; Wang, TY; Wu, JB | 1 |
Chang, Y; Guo, F; Jiang, H; Liu, B; Wang, Q | 1 |
Chen, Y; Huang, Z; Liu, Y; Wu, Y; Yi, J | 1 |
Li, J; Liu, Y; Ma, X | 1 |
Feng, NP; Liu, Y; Shi, F; Wang, Z; Zhang, SJ; Zhang, YT; Zhao, JH; Zhong, YZ | 1 |
Chen, F; Ding, J; He, L; Li, Y; Peng, J; Xu, S; Zhang, J | 1 |
Cai, J; Li, W; Lin, C; Lin, G; Ma, J; Pan, J; Pan, X; Wang, X | 1 |
Bubenyák, M | 1 |
Bao, T; Dong, Y; Li, Y; Weng, X; Yang, Q; Zhang, Y; Zhu, X | 1 |
Hu, CQ; Li, F; Yang, XW | 1 |
Chen, F; Ding, JS; Li, D; Li, S | 1 |
Feng, NP; Huang, ZB; Liu, Y; Wang, Z; Zhang, SJ; Zhang, YT; Zhao, JH | 1 |
Chen, Y; Huang, Z; Liu, Y; Tang, X; Yi, J; Zhao, J | 1 |
Ivanova, B; Spiteller, M | 1 |
Jin, HW; Qian, P; Yang, XW | 1 |
Liu, L; Moore, DJ; Roongta, V; Wen, B | 1 |
Fu, Q; Jin, Y; Li, K; Li, Z; Liang, T | 1 |
Domonkos, C; Fitos, I; Visy, J; Zsila, F | 1 |
Cai, Q; Li, W; Shi, S; Wang, Q; Wei, J; Wei, R; Zhang, Y; Zhao, W | 1 |
Missler, SR; Rebhun, JF; Roloff, SJ; Velliquette, RA | 1 |
Cheng, Y; Li, X; Wang, X; Xue, H; Yue, Y; Zhang, W | 1 |
Chen, B; Hu, H; Huang, M; Lei, J; Li, Y; Lu, J; Wang, Z; Xie, W; Yu, L; Zeng, K; Zeng, S | 1 |
Gong, M; He, R; He, S; Lu, X; Pan, X; Wu, Y; Xu, Y | 1 |
Gao, B; Guo, H; Liu, D; Ren, H; Santos, HA; Xu, F; You, M; Zhang, H; Zhang, X | 1 |
Feng, NP; He, ZH; Li, Z; Xia, Q; Zhang, HY; Zhang, K; Zhang, YT; Zhao, JH | 1 |
Bisson, WH; Gonzalez, FJ; Krausz, KW; Sun, D; Xie, C; Yagai, T; Yan, T; Yang, X; Zhang, L; Zhang, Y; Zheng, Y | 1 |
Aisa, HA; Cao, JG; Huang, GZ; Liu, FZ; Nie, LF; Wang, SS; Xiamuxi, H | 1 |
Li, JJ; Tian, KM; Xu, SW | 1 |
Chen, Z; Liu, Y; Mao, Z; Zhou, W | 1 |
Chen, Z; Zhang, B | 1 |
Ge, J; Li, X; Liu, R; Sun, R; Zhang, J; Zheng, Q | 1 |
Chen, P; Jia, J; Jia, Y; Li, H; Wang, X; Wang, Y; Xiu, R; Xue, Y; Zhang, G; Zhang, X; Zhao, Z | 1 |
Chu, QR; Du, SS; He, YH; Li, HX; Liu, YQ; Tang, C; Wang, JR; Wu, TL; Yang, CJ; Zhang, ZJ | 1 |
Guo, H; Jin, R; Liu, J; Tang, Y; Wang, Y; Yan, H; Zhou, J | 1 |
2 review(s) available for rutecarpine and evodiamine
Article | Year |
---|---|
Rutaecarpine: A promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu).
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Evodia; Humans; Hypolipidemic Agents; Indole Alkaloids; Platelet Aggregation Inhibitors; Quinazolines; Vasodilator Agents | 2019 |
Evodiamine and rutaecarpine from Tetradium ruticarpum in the treatment of liver diseases.
Topics: Animals; Evodia; Humans; Indole Alkaloids; Liver Diseases; Plants, Medicinal; Quinazolines | 2020 |
58 other study(ies) available for rutecarpine and evodiamine
Article | Year |
---|---|
Partial Activation and Inhibition of TRPV1 Channels by Evodiamine and Rutaecarpine, Two Major Components of the Fruits of Evodia rutaecarpa.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Evodia; Fruit; HEK293 Cells; Humans; Indole Alkaloids; Molecular Structure; Quinazolines; TRPV Cation Channels | 2016 |
[On the evaluation of the preparation of Chinese medicinal prescriptions. VI. The changes of the alkaloid contents by processing of Evodia fruit].
Topics: Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Indole Alkaloids; Plant Extracts; Quinazolines; Quinolones; Taste | 1991 |
Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa.
Topics: Alkaloids; Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indole Alkaloids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Vasodilator Agents | 1996 |
[A simultaneous determination of evodiamine and rutaecarpine in oriental pharmaceutical decoctions containing Evodia fruit by ion-pair high-performance liquid chromatography].
Topics: Alkaloids; Cardiotonic Agents; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Indole Alkaloids; Plant Extracts; Quinazolines | 1996 |
Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components.
Topics: Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; China; Chromatography, High Pressure Liquid; Indole Alkaloids; Limonins; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Triterpenes; Vasodilator Agents | 1997 |
The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors.
Topics: Alkaloids; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Dose-Response Relationship, Drug; Fruit; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Indole Alkaloids; Male; Myocardial Contraction; Plant Extracts; Platelet Aggregation Inhibitors; Purinergic Antagonists; Pyridoxal Phosphate; Quinazolines; Receptors, Drug; Rosales; Ruthenium Red; Stimulation, Chemical | 2001 |
The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.
Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Indole Alkaloids; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Plant Extracts; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Theophylline | 2002 |
Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.
Topics: Alkaloids; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drugs, Chinese Herbal; Glucuronosyltransferase; Glutathione Transferase; Humans; Indole Alkaloids; Liver; Male; Methanol; Mice; Mice, Inbred C57BL; Oxazines; Plant Extracts; Plants, Medicinal; Quinazolines; Rutaceae | 2002 |
Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.
Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Division; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Evodia; Fibrosarcoma; Fluorouracil; Furans; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HeLa Cells; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Melanoma; Mice; Mitochondria; Molecular Structure; Neoplasm Proteins; Oligopeptides; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Rats; Rats, Inbred BUF; Sarcoma 180; Tumor Cells, Cultured | 2003 |
[Determination of evodiamine and rutaecarpine in Evodia rutaecarpa (Juss.) Benth after compatibility with Coptis chinensis Franch].
Topics: Alkaloids; Coptis; Drug Combinations; Drugs, Chinese Herbal; Evodia; Indole Alkaloids; Plant Extracts; Plants, Medicinal; Quinazolines | 2001 |
[Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth].
Topics: Alkaloids; Carbolines; Evodia; Fruit; Indole Alkaloids; Molecular Structure; Plant Extracts; Plants, Medicinal; Quinazolines | 2004 |
Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
Topics: Active Transport, Cell Nucleus; Alkaloids; Annexin A5; Apoptosis; Carcinogens; Cell Line, Tumor; Cell Proliferation; Collagen; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Enzyme Activation; Evodia; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; I-kappa B Kinase; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Indole Alkaloids; Inflammation; Laminin; MAP Kinase Signaling System; Microscopy, Fluorescence; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Protein Serine-Threonine Kinases; Proteoglycans; Quinazolines; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species.
Topics: Chromatography, High Pressure Liquid; Evodia; Fruit; Indole Alkaloids; Medicine, Chinese Traditional; Molecular Structure; Phenethylamines; Plant Extracts; Plants, Medicinal; Polyethylene Glycols; Psychotropic Drugs; Quinazolines; Reproducibility of Results; Solvents; Stereoisomerism; Synephrine; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Leukotriene C4; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Mice; NF-kappa B; Plant Extracts; Quinazolines | 2006 |
Determination of evodiamine and rutecarpine in human serum by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Evodia; Humans; Indole Alkaloids; Mass Spectrometry; Plant Extracts; Quinazolines; Reproducibility of Results; Tandem Mass Spectrometry | 2006 |
Chemical and biological comparisons on Evodia with two related species of different locations and conditions.
Topics: Alkaloids; Animals; Aorta; China; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Evodia; Female; Fruit; In Vitro Techniques; Indole Alkaloids; Male; Methanol; Molecular Structure; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Species Specificity; Synephrine; Taiwan | 2006 |
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate | 2007 |
In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents.
Topics: Alkaloids; Animals; Anti-Allergic Agents; Behavior, Animal; Cell Degranulation; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Plant Extracts; Pruritus; Quinazolines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2007 |
[Methodological studies on equivalent relationship between granule for clinical prescription and clinical decoction of fructus evodiae].
Topics: Alkaloids; Animals; Drugs, Chinese Herbal; Evodia; Female; Fruit; Hot Temperature; Indole Alkaloids; Male; Mice; Mice, Inbred ICR; Pain Threshold; Plant Extracts; Plants, Medicinal; Quinazolines; Technology, Pharmaceutical | 2007 |
The permeability and the efflux of alkaloids of the Evodiae fructus in the Caco-2 model.
Topics: Alkaloids; Biological Transport, Active; Caco-2 Cells; Chromatography, High Pressure Liquid; Evodia; Humans; Indole Alkaloids; Intestinal Absorption; Permeability; Plant Extracts; Quinazolines | 2009 |
Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation.
Topics: Cell Line; Cell Movement; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Immunoblotting; Indole Alkaloids; Intercellular Adhesion Molecule-1; Monocytes; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Plant Extracts; Protein Serine-Threonine Kinases; Quinazolines; Reactive Oxygen Species; Receptors, CCR2; Tumor Necrosis Factor Ligand Superfamily Member 14 | 2009 |
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Cyclic AMP; Desoxycorticosterone; Drugs, Chinese Herbal; Evodia; Hydroxycholesterols; Indole Alkaloids; Male; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents; Zona Fasciculata; Zona Reticularis | 2009 |
[Study on vitro release and transdermal behaviors of Yulian cataplasm].
Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Indole Alkaloids; Mice; Plant Extracts; Quinazolines; Skin; Skin Absorption | 2009 |
[Assay of evodin, evodiamine and rutaecarpine in Fructus Evodiae by QAMS].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Evodia; Furans; Heterocyclic Compounds, 4 or More Rings; Indole Alkaloids; Plant Extracts; Quinazolines | 2009 |
[Determination of evodiamine and rutaecarpine of compound Wuzhuyu cataplasm in plasma by SPE-HPLC: application to its pharmacokinetics].
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Indole Alkaloids; Male; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Solid Phase Extraction | 2009 |
Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO.
Topics: Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Evodia; G2 Phase; Humans; In Situ Nick-End Labeling; Indole Alkaloids; Plant Extracts; Poly(ADP-ribose) Polymerases; Quinazolines; Thyroid Neoplasms; Time Factors | 2010 |
A new quinolone and other constituents from the fruits of Tetradium ruticarpum: effects on neutrophil pro-inflammatory responses.
Topics: Anti-Inflammatory Agents; Evodia; Fruit; Humans; Indole Alkaloids; Molecular Structure; Neutrophils; Pancreatic Elastase; Plant Extracts; Quinazolines; Quinolines; Quinolones; Superoxides | 2010 |
Optimization of extraction of evodiamine and rutaecarpine from fruit of Evodia rutaecarpa using modified supercritical CO(2).
Topics: Algorithms; Analysis of Variance; Carbon Dioxide; Chemical Fractionation; Chromatography, High Pressure Liquid; Evodia; Fruit; Indole Alkaloids; Methanol; Plant Extracts; Pressure; Quinazolines; Temperature; Time Factors | 2010 |
[Optimization of a HPLC determination method for Evodia rutaecarpa].
Topics: Chromatography, High Pressure Liquid; Evodia; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines | 2011 |
[Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC].
Topics: Alkaloids; Capsules; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Linear Models; Quality Control; Quinazolines; Reproducibility of Results | 2011 |
Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion.
Topics: Administration, Cutaneous; Animals; Emulsions; Indole Alkaloids; Male; Microdialysis; Microscopy, Electron, Transmission; Pharmaceutical Vehicles; Quinazolines; Rats; Rats, Sprague-Dawley; Skin Absorption | 2011 |
Pharmacokinetic comparisons of rutaecarpine and evodiamine after oral administration of Wu-Chu-Yu extracts with different purities to rats.
Topics: Administration, Oral; Alkaloids; Animals; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Evodia; Indole Alkaloids; Intestinal Absorption; Male; Plant Extracts; Quinazolines; Quinolines; Rats; Rats, Sprague-Dawley; Reference Standards | 2012 |
Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics.
Topics: Animals; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Half-Life; Indicators and Reagents; Indole Alkaloids; Injections, Intravenous; Male; Quinazolines; Rabbits; Reference Standards; Reproducibility of Results; Solutions; Spectrometry, Mass, Electrospray Ionization | 2011 |
[Synthesis, physicochemical and pharmacological properties of pentacyclic alkaloid-analogues].
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Survival; Drugs, Chinese Herbal; Evodia; HeLa Cells; Humans; Indole Alkaloids; Piroxicam; Plant Extracts; Quinazolines; Therapeutic Equivalency | 2011 |
[Studies on pharmacokinetics of evodiamine and rutaecarpine in rats plasma after oral administration extracts of euodiae fructus].
Topics: Administration, Oral; Animals; Evodia; Indole Alkaloids; Male; Plant Extracts; Quinazolines; Rats; Rats, Wistar | 2011 |
Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction.
Topics: Administration, Oral; Alkaloids; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Indole Alkaloids; Male; Molecular Structure; Quinazolines; Rats | 2012 |
Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.
Topics: Administration, Cutaneous; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Female; Indole Alkaloids; Male; Mice; Oleic Acid; Pain; Plant Extracts; Quinazolines; Sesquiterpenes; Skin; Swine | 2012 |
In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion.
Topics: Animals; Emulsions; Fibroblasts; Indole Alkaloids; Mice; Microscopy, Confocal; Nanoparticles; NIH 3T3 Cells; Particle Size; Quinazolines; Rhodamines | 2012 |
Simultaneous determination of six bioactive compounds in Evodiae Fructus by high-performance liquid chromatography with diode array detection.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Evodia; Fruit; Indole Alkaloids; Limonins; Plant Extracts; Quinazolines; Reproducibility of Results; Triterpenes | 2014 |
Evodiamine and rutaecarpine alkaloids as highly selective transient receptor potential vanilloid 1 agonists.
Topics: Animals; Humans; Indole Alkaloids; Models, Molecular; Protein Conformation; Quinazolines; Rabbits; Rats; Substrate Specificity; TRPV Cation Channels | 2014 |
New limonoids from Coptidis Rhizoma-Euodiae Fructus couple.
Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Evodia; Fruit; Humans; Indole Alkaloids; Limonins; Molecular Structure; Quinazolines; Rhizome | 2014 |
Metabolic activation of the indoloquinazoline alkaloids evodiamine and rutaecarpine by human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4.
Topics: Activation, Metabolic; Cytochrome P-450 CYP3A; Humans; Hydrogenation; Indole Alkaloids; Microsomes, Liver; Plant Extracts; Quinazolines | 2014 |
[Fast analysis of indole alkaloids from Evodiae fructus by supercritical fluid chromatography].
Topics: Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Evodia; Indole Alkaloids; Quinazolines | 2014 |
Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine.
Topics: Binding Sites; Circular Dichroism; Humans; Indole Alkaloids; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Quinazolines; Serum Albumin; Spectrophotometry, Ultraviolet; Stereoisomerism | 2014 |
Toxicity of Evodiae fructus on rat liver mitochondria: the role of oxidative stress and mitochondrial permeability transition.
Topics: Adenosine Triphosphate; Animals; Cytochromes c; Evodia; Furans; Glutathione; Heterocyclic Compounds, 4 or More Rings; Indole Alkaloids; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxidative Stress; Permeability; Plant Extracts; Quinazolines; Rats; Superoxide Dismutase | 2014 |
Identification of evodiamine as the bioactive compound in evodia (Evodia rutaecarpa Benth.) fruit extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ).
Topics: Animals; CHO Cells; Chromans; Chromatography, High Pressure Liquid; Cricetulus; Evodia; Fruit; Hep G2 Cells; Humans; Indole Alkaloids; Mass Spectrometry; Molecular Structure; Plant Extracts; PPAR gamma; Quinazolines; Thiazolidinediones; Troglitazone | 2015 |
Rutaecarpine and evodiamine selected as β1-AR inhibitor candidates using β1-AR/CMC-offline-UPLC/MS prevent cardiac ischemia-reperfusion injury via energy modulation.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Cell Membrane; Cell Survival; CHO Cells; Chromatography, High Pressure Liquid; Cricetulus; Energy Metabolism; Evodia; Indole Alkaloids; Male; Mass Spectrometry; Myocardial Reperfusion Injury; Quinazolines; Rats, Wistar; Receptors, Adrenergic, beta-1 | 2015 |
Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor.
Topics: Alkaloids; Animals; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Evodia; Forkhead Box Protein O1; Gene Expression Regulation; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Hypoglycemic Agents; Indole Alkaloids; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoenolpyruvate Carboxykinase (ATP); Primary Cell Culture; Quinazolines; Receptors, Cytoplasmic and Nuclear; Signal Transduction | 2016 |
Optimization of combinations of ginsenoside-Rg1, ginsenoside-Rb1, evodiamine and rutaecarpine for effective therapy of mouse migraine.
Topics: Animals; Dopamine; Drug Combinations; Drugs, Chinese Herbal; Ginsenosides; Indole Alkaloids; Medicine, Chinese Traditional; Mice, Inbred ICR; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Phytotherapy; Quinazolines; Serotonin | 2016 |
Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Quinazolines; Spectrum Analysis; Spheroids, Cellular; Tumor Cells, Cultured | 2016 |
Co-delivery of evodiamine and rutaecarpine in a microemulsion-based hyaluronic acid hydrogel for enhanced analgesic effects on mouse pain models.
Topics: Analgesics; Animals; Dinoprostone; Drug Carriers; Emulsions; Guinea Pigs; Hyaluronic Acid; Hydrogels; Indole Alkaloids; Interleukin-6; Mice; Pain; Quinazolines; Skin Absorption; Tumor Necrosis Factor-alpha | 2017 |
Structure-Activity Relationships of the Main Bioactive Constituents of
Topics: Alkaloids; Animals; Bile Acids and Salts; Cell Line, Tumor; Drugs, Chinese Herbal; Evodia; Genes, Reporter; Hep G2 Cells; Hepatocytes; Homeostasis; Humans; Indole Alkaloids; Liver; Male; Mice; Mice, Inbred C57BL; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Structure-Activity Relationship; Up-Regulation | 2018 |
Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-
Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Indole Alkaloids; Lung Neoplasms; Molecular Structure; Pyrimidinones; Quinazolines; Structure-Activity Relationship | 2020 |
Analysis of Evodiae Fructus by capillary electrochromatography-mass spectrometry with methyl-vinylimidazole functionalized organic polymer monolilth as stationary phases.
Topics: Acetonitriles; Ammonia; Calibration; Capillary Electrochromatography; Drugs, Chinese Herbal; Electrolytes; Evodia; Fruit; Hydrogen-Ion Concentration; Imidazoles; Indole Alkaloids; Limit of Detection; Limonins; Mass Spectrometry; Polymers; Quinazolines; Reference Standards; Reproducibility of Results | 2019 |
Screening of cathepsin B inhibitors in traditional Chinese medicine by capillary electrophoresis with immobilized enzyme microreactor.
Topics: Amaryllidaceae Alkaloids; Cathepsin B; Drug Discovery; Drugs, Chinese Herbal; Electrophoresis, Capillary; Enzymes, Immobilized; Feasibility Studies; Indole Alkaloids; Indolizines; Kaempferols; Molecular Docking Simulation; Quinazolines; Theophylline | 2019 |
Identification of evodiamine and rutecarpine as novel TMEM16A inhibitors and their inhibitory effects on peristalsis in isolated Guinea-pig ileum.
Topics: Animals; Cricetulus; Guinea Pigs; Indole Alkaloids; Interstitial Cells of Cajal; Peristalsis; Quinazolines | 2021 |
Design, synthesis and biological evaluation of novel evodiamine and rutaecarpine derivatives against phytopathogenic fungi.
Topics: Antifungal Agents; Ascomycota; Botrytis; Dose-Response Relationship, Drug; Drug Design; Fusarium; Indole Alkaloids; Microbial Sensitivity Tests; Molecular Structure; Quinazolines; Rhizoctonia; Structure-Activity Relationship | 2022 |
Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study.
Topics: Antineoplastic Agents; Evodia; Indole Alkaloids; Ligands; Molecular Docking Simulation; Quinazolines; Quinazolinones | 2022 |