rupatadine has been researched along with fluorouracil in 2 studies
| Studies (rupatadine) | Trials (rupatadine) | Recent Studies (post-2010) (rupatadine) | Studies (fluorouracil) | Trials (fluorouracil) | Recent Studies (post-2010) (fluorouracil) |
|---|---|---|---|---|---|
| 116 | 43 | 62 | 45,562 | 9,307 | 14,663 |
| Protein | Taxonomy | rupatadine (IC50) | fluorouracil (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.32 | |
| Thymidylate synthase | Mus musculus (house mouse) | 1.58 | |
| Aromatase | Homo sapiens (human) | 0.63 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohamed, MZ; Mohammed, HH | 1 |
| Abdalla, AM; Abdelbaky, FAF; Abdelzaher, WY; Hafez, SMNA; Khalaf, HM; Welson, NN | 1 |
2 other study(ies) available for rupatadine and fluorouracil
| Article | Year |
|---|---|
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability.
Topics: Animals; Apoptosis; Aspartic Acid Proteases; Carboxymethylcellulose Sodium; Caspase 3; Cysteine; Fluorouracil; Glutathione; Histamine; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Irritants; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Permeability; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2022 |
Role of Platelet-activating factor and HO-1 in mediating the protective effect of rupatadine against 5-fluorouracil-induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyproheptadine; Fluorouracil; Heme Oxygenase-1; Liver; Male; Oxidative Stress; Platelet Activating Factor; Rats | 2022 |