Page last updated: 2024-09-04

rupatadine and diphenhydramine

rupatadine has been researched along with diphenhydramine in 2 studies

Compound Research Comparison

Studies
(rupatadine)
Trials
(rupatadine)
Recent Studies (post-2010)
(rupatadine)
Studies
(diphenhydramine)
Trials
(diphenhydramine)
Recent Studies (post-2010) (diphenhydramine)
11643624,146415542

Protein Interaction Comparison

ProteinTaxonomyrupatadine (IC50)diphenhydramine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.98
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.542
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.05
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.372
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.162
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.346
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.647
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.542
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.295
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.98
Histamine H1 receptorHomo sapiens (human)0.171
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.118
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.8852

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Almansa, C; Balsa, D; BartrolĂ­, J; Carceller, E; Forn, J; GarcĂ­a-Rafanell, J; Giral, M; Merlos, M1
Didiodato, G; Gerard, L; Hopkins, S; Kotchetkov, R; McLean, J; Nay, D1

Other Studies

2 other study(ies) available for rupatadine and diphenhydramine

ArticleYear
[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Anaphylaxis; Animals; Benzocycloheptenes; Blood Pressure; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Muscle Contraction; Muscle, Smooth; Piperidines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Premedication with montelukast and rupatadine decreased rituximab infusion time, rate, severity of reactions and use of rescue medications.
    International journal of cancer, 2020, 10-01, Volume: 147, Issue:7

    Topics: Acetaminophen; Acetates; Adult; Aged; Aged, 80 and over; Cyclopropanes; Cyproheptadine; Diphenhydramine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lymphoproliferative Disorders; Male; Middle Aged; Premedication; Quinolines; Rituximab; Standard of Care; Sulfides; Treatment Outcome

2020