rufinamide has been researched along with topiramate in 9 studies
| Studies (rufinamide) | Trials (rufinamide) | Recent Studies (post-2010) (rufinamide) | Studies (topiramate) | Trials (topiramate) | Recent Studies (post-2010) (topiramate) |
|---|---|---|---|---|---|
| 175 | 22 | 118 | 3,197 | 557 | 1,329 |
| Protein | Taxonomy | rufinamide (IC50) | topiramate (IC50) |
|---|---|---|---|
| Carbonic anhydrase 1 | Homo sapiens (human) | 0.25 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.8683 | |
| Carbonic anhydrase 2 | Rattus norvegicus (Norway rat) | 1.4 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.054 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aldenkamp, AP | 1 |
| Verdian, L; Yi, Y | 1 |
| Benedict, A; Maclaine, G; Verdian, L | 1 |
| Burrall, B; Konia, T; Shahbaz, S; Sivamani, RK | 1 |
| Ito, S; Oguni, H | 1 |
| Ohtsuka, Y | 1 |
| Bebin, EM; Cutter, GR; Gaston, TE; Liu, Y; Szaflarski, JP | 1 |
| Brigo, F; Eltze, C; Jones, K; Matricardi, S | 1 |
4 review(s) available for rufinamide and topiramate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of pediatric epilepsy].
Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid | 2014 |
[New antiepileptic drugs: characteristics and clinical applications].
Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Lamotrigine; Levetiracetam; Piracetam; Safety; Topiramate; Triazines; Triazoles | 2014 |
Anti-seizure medications for Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Cannabidiol; Child; Child, Preschool; Cinnamates; Clobazam; Electroencephalography; Felbamate; Humans; Lamotrigine; Lennox Gastaut Syndrome; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Topiramate; Triazoles; Wakefulness; Young Adult | 2021 |
5 other study(ies) available for rufinamide and topiramate
| Article | Year |
|---|---|
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |
Cost-utility analysis of rufinamide versus topiramate and lamotrigine for the treatment of children with Lennox-Gastaut Syndrome in the United Kingdom.
Topics: Anticonvulsants; Child; Confidence Intervals; Cost-Benefit Analysis; Drug Utilization; Epilepsy; Follow-Up Studies; Fructose; Health Status; Humans; Lamotrigine; Markov Chains; Quality of Life; Sensitivity and Specificity; Topiramate; Triazines; Triazoles; United Kingdom | 2010 |
The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Computer Simulation; Cost-Benefit Analysis; Epilepsy, Absence; Fructose; Health Care Costs; Humans; Infant; Intellectual Disability; Lamotrigine; Models, Economic; Randomized Controlled Trials as Topic; Syndrome; Time Factors; Topiramate; Treatment Outcome; Triazines; Triazoles; United Kingdom | 2010 |
A case of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) related to rufinamide.
Topics: Anti-Inflammatory Agents; Anticonvulsants; Child; Drug Hypersensitivity Syndrome; Epilepsy, Complex Partial; Fructose; Humans; Levetiracetam; Male; Piracetam; Prednisone; Topiramate; Triazoles | 2013 |
Interactions between cannabidiol and commonly used antiepileptic drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Benzodiazepines; Cannabidiol; Child; Child, Preschool; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Topiramate; Triazoles; Young Adult | 2017 |