rufinamide has been researched along with lacosamide in 9 studies
| Studies (rufinamide) | Trials (rufinamide) | Recent Studies (post-2010) (rufinamide) | Studies (lacosamide) | Trials (lacosamide) | Recent Studies (post-2010) (lacosamide) |
|---|---|---|---|---|---|
| 175 | 22 | 118 | 727 | 90 | 625 |
| Protein | Taxonomy | rufinamide (IC50) | lacosamide (IC50) |
|---|---|---|---|
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | 0.415 | |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | 0.182 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Miura, Y | 1 |
| Hussar, DA | 1 |
| Perucca, E; Prunetti, P | 1 |
| Darshan, DV; Nagaveni, V; Prabhakar, S; Sravani, M; Vairamani, M | 1 |
| Dogaru, MT; Gáll, Z; Szilágyi, T; Vancea, S | 1 |
| de Paoli, FV; Nielsen, OB; Pedersen, TH; Skov, M | 1 |
| Arslan, EA; Cansu, A; Dilber, B; Esenülkü, G; Gürgen, SG; Kamaşak, T; Kart, PÖ; Şahin, S; Sarsmaz, HY; Topsakal, AS; Yazar, U; Yıldız, N | 1 |
| Chong, E; Kim, DJ; Kim, SM; Lee, SY; Oh, H | 1 |
3 review(s) available for rufinamide and lacosamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[A new aspect in the research on antiepileptic drugs].
Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles | 2007 |
New and forthcoming anti-epileptic drugs.
Topics: Acetamides; Anticonvulsants; Clinical Trials as Topic; Dioxolanes; Drug Approval; Drug Discovery; Epilepsy; Humans; Lacosamide; Remission Induction; Triazoles | 2011 |
6 other study(ies) available for rufinamide and lacosamide
| Article | Year |
|---|---|
New Drugs2010, PART 1.
Topics: Acetamides; Antibodies, Monoclonal; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Azepines; Benzazepines; Benzhydryl Compounds; Benzyl Alcohol; Benzylamines; Cyclams; Cyclopropanes; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Ethanolamines; Everolimus; Febuxostat; Fluorenes; Fluoroquinolones; Gout Suppressants; Heterocyclic Compounds; Humans; Immunosuppressive Agents; Indoles; Lacosamide; Milnacipran; Oligopeptides; Phenols; Selective Serotonin Reuptake Inhibitors; Sirolimus; Tapentadol; Thiazoles; Tolvaptan; Triazoles | 2010 |
Study on the noncovalent interactions of antiepileptic drugs and amyloid β 1-40 peptide by electrospray ionization mass spectrometry.
Topics: Acetamides; Amino Acid Sequence; Amyloid beta-Peptides; Anticonvulsants; Humans; Lacosamide; Molecular Sequence Data; Peptide Fragments; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Triazoles | 2012 |
Liquid chromatography-mass spectrometric determination of rufinamide in low volume plasma samples.
Topics: Acetamides; Animals; Chromatography, High Pressure Liquid; Humans; Lacosamide; Limit of Detection; Rabbits; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Triazoles | 2013 |
The anti-convulsants lacosamide, lamotrigine, and rufinamide reduce myotonia in isolated human and rat skeletal muscle.
Topics: Acetamides; Animals; Anthracenes; Anticonvulsants; Area Under Curve; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Female; Humans; In Vitro Techniques; Isometric Contraction; Lacosamide; Lamotrigine; Male; Muscle, Skeletal; Myotonia; Rats; Rats, Wistar; Triazines; Triazoles | 2017 |
An investigation of the effects of chronic zonisamide, sultiam, lacosamide, clobazam, and rufinamide anti-seizure medications on foliculogenesis in ovarian tissue in prepubertal non-epileptic rats.
Topics: Animals; Clobazam; Female; Lacosamide; Rats; Rats, Wistar; Thiazines; Triazoles; Zonisamide | 2022 |
Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Anticonvulsants; Chromatography, Liquid; Gabapentin; Lacosamide; Pregabalin; Tandem Mass Spectrometry; Vigabatrin | 2024 |