Page last updated: 2024-09-03

ruboxyl and fluorouracil

ruboxyl has been researched along with fluorouracil in 2 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies (ruboxyl)	Trials (ruboxyl)	Recent Studies (post-2010) (ruboxyl)	Studies (fluorouracil)	Trials (fluorouracil)	Recent Studies (post-2010) (fluorouracil)
26	1	2	45,562	9,307	14,663

Protein Interaction Comparison

Protein	Taxonomy	fluorouracil (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.32
Thymidylate synthase	Mus musculus (house mouse)	1.58
Aromatase	Homo sapiens (human)	0.63

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
D'iachkovskaia, RF; Ganieva, LKh; Konovalova, NP; Lapshin, IM; Volkova, LM	1
Codacci-Pisanelli, D; Franchi, F; Konovalova, NP; Seminara, P; Volkova, LM	1

Other Studies

2 other study(ies) available for ruboxyl and fluorouracil

Article	Year
[Sensitivity of human tumor heterografts to a spin-labelled rubomycin derivative]. Eksperimental'naia onkologiia, 1988, Volume: 10, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Humans; Mice; Neoplasms; Neoplasms, Experimental; Spin Labels; Subrenal Capsule Assay; Transplantation, Heterologous	1988
[Effect of Ruboxyl (nitroxyl derivative of daunorubicin) on hepatic metastases of colorectal carcinoma]. Voprosy onkologii, 2000, Volume: 46, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Daunorubicin; Fluorouracil; Infusions, Intravenous; Liver Neoplasms; Mice; Rats	2000

Article

Year

[Sensitivity of human tumor heterografts to a spin-labelled rubomycin derivative].

Eksperimental'naia onkologiia, 1988, Volume: 10, Issue:4

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Humans; Mice; Neoplasms; Neoplasms, Experimental; Spin Labels; Subrenal Capsule Assay; Transplantation, Heterologous

1988

[Effect of Ruboxyl (nitroxyl derivative of daunorubicin) on hepatic metastases of colorectal carcinoma].

Voprosy onkologii, 2000, Volume: 46, Issue:4

Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Daunorubicin; Fluorouracil; Infusions, Intravenous; Liver Neoplasms; Mice; Rats

2000