Page last updated: 2024-09-04

ruboxistaurin and u 0126

ruboxistaurin has been researched along with u 0126 in 3 studies

Compound Research Comparison

Studies
(ruboxistaurin)
Trials
(ruboxistaurin)
Recent Studies (post-2010)
(ruboxistaurin)
Studies
(u 0126)
Trials
(u 0126)
Recent Studies (post-2010) (u 0126)
20329562,81621,213

Protein Interaction Comparison

ProteinTaxonomyruboxistaurin (IC50)u 0126 (IC50)
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.29
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.25
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.07
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)0.2816
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)0.2529

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Braunstein, TH; Domínguez, H; Fossum, A; Guterbaum, TJ; Holstein-Rathlou, NH; Torp-Pedersen, CT1

Other Studies

3 other study(ies) available for ruboxistaurin and u 0126

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration.
    Journal of vascular research, 2013, Volume: 50, Issue:5

    Topics: Acetylcysteine; Butadienes; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Maleimides; MAP Kinase Kinase Kinases; Mitochondria; Nitric Oxide Synthase Type III; Nitriles; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; rho-Associated Kinases; Threonine

2013