ruboxistaurin has been researched along with u 0126 in 3 studies
| Studies (ruboxistaurin) | Trials (ruboxistaurin) | Recent Studies (post-2010) (ruboxistaurin) | Studies (u 0126) | Trials (u 0126) | Recent Studies (post-2010) (u 0126) |
|---|---|---|---|---|---|
| 203 | 29 | 56 | 2,816 | 2 | 1,213 |
| Protein | Taxonomy | ruboxistaurin (IC50) | u 0126 (IC50) |
|---|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 0.29 | |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | 0.25 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.07 | |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | 0.2816 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 0.2529 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Braunstein, TH; Domínguez, H; Fossum, A; Guterbaum, TJ; Holstein-Rathlou, NH; Torp-Pedersen, CT | 1 |
3 other study(ies) available for ruboxistaurin and u 0126
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration.
Topics: Acetylcysteine; Butadienes; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Maleimides; MAP Kinase Kinase Kinases; Mitochondria; Nitric Oxide Synthase Type III; Nitriles; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; rho-Associated Kinases; Threonine | 2013 |