ruboxistaurin has been researched along with pd 98059 in 3 studies
| Studies (ruboxistaurin) | Trials (ruboxistaurin) | Recent Studies (post-2010) (ruboxistaurin) | Studies (pd 98059) | Trials (pd 98059) | Recent Studies (post-2010) (pd 98059) |
|---|---|---|---|---|---|
| 203 | 29 | 56 | 4,939 | 3 | 1,001 |
| Protein | Taxonomy | ruboxistaurin (IC50) | pd 98059 (IC50) |
|---|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 2.8 | |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | 6.3 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 2.8 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 2.8 | |
| Dual specificity mitogen-activated protein kinase kinase 2 | Rattus norvegicus (Norway rat) | 4.2 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Rattus norvegicus (Norway rat) | 4.2 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Chou, E; Gabriele, A; Ha, SW; King, GL; Meier, M; Naruse, K; Park, JY; Rhodes, CJ; Suzuma, K; Takahara, N; Yamauchi, T | 1 |
| Andrassy, M; Belov, D; Harja, E; Katus, HA; Leitges, M; Nawroth, PP; Schmidt, AM; Yan, SD; Yan, SF; Zou, YS | 1 |
3 other study(ies) available for ruboxistaurin and pd 98059
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.
Topics: Animals; Capillaries; Cattle; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Glucose; Indoles; Isoenzymes; Maleimides; Pericytes; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Retinal Vessels; RNA, Messenger; Transcription, Genetic | 2000 |
Central role of PKCbeta in neointimal expansion triggered by acute arterial injury.
Topics: Animals; Aorta; Blood Glucose; Cell Division; Cell Movement; Cells, Cultured; Constriction, Pathologic; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Femoral Artery; Flavonoids; Humans; Immediate-Early Proteins; Indoles; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Maleimides; Mesylates; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Peroxidase; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Tunica Intima | 2005 |