ruboxistaurin has been researched along with acetylcysteine in 4 studies
| Studies (ruboxistaurin) | Trials (ruboxistaurin) | Recent Studies (post-2010) (ruboxistaurin) | Studies (acetylcysteine) | Trials (acetylcysteine) | Recent Studies (post-2010) (acetylcysteine) |
|---|---|---|---|---|---|
| 203 | 29 | 56 | 14,580 | 1,046 | 5,960 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kowluru, RA | 1 |
| Gao, X; Irwin, MG; Lei, S; Liu, Y; Mao, X; Vanhoutte, PM; Wang, T; Wong, GT; Xia, Z | 1 |
| Braunstein, TH; Domínguez, H; Fossum, A; Guterbaum, TJ; Holstein-Rathlou, NH; Torp-Pedersen, CT | 1 |
| Alicic, RZ; Tuttle, KR | 1 |
1 review(s) available for ruboxistaurin and acetylcysteine
| Article | Year |
|---|---|
Novel therapies for diabetic kidney disease.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Antioxidants; Bosentan; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelins; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Indoles; Janus Kinases; Maleimides; Polyamines; Protein Kinase C; Pyridones; Pyridoxamine; Sevelamer; Sulfonamides | 2014 |
3 other study(ies) available for ruboxistaurin and acetylcysteine
| Article | Year |
|---|---|
Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are interrelated.
Topics: Acetylcysteine; Animals; Cells, Cultured; Diabetic Retinopathy; Enzyme Inhibitors; Free Radical Scavengers; Glucose; Indoles; Male; Maleimides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Protein Kinase C; Rats; Rats, Sprague-Dawley; Retina; Thiobarbituric Acid Reactive Substances | 2001 |
PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.
Topics: Acetylcysteine; Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dinoprost; Drug Evaluation, Preclinical; Enzyme Activation; Free Radical Scavengers; Hypertrophy, Left Ventricular; Indoles; Isoprostanes; Male; Maleimides; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Superoxides; Ultrasonography | 2012 |
Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration.
Topics: Acetylcysteine; Butadienes; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Maleimides; MAP Kinase Kinase Kinases; Mitochondria; Nitric Oxide Synthase Type III; Nitriles; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; rho-Associated Kinases; Threonine | 2013 |