ru 59063 has been researched along with bicalutamide in 2 studies
*bicalutamide: approved for treatment of advanced prostate cancer [MeSH]
*bicalutamide: approved for treatment of advanced prostate cancer [MeSH]
| Studies (ru 59063) | Trials (ru 59063) | Recent Studies (post-2010) (ru 59063) | Studies (bicalutamide) | Trials (bicalutamide) | Recent Studies (post-2010) (bicalutamide) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 1,313 | 212 | 541 |
| Protein | Taxonomy | ru 59063 (IC50) | bicalutamide (IC50) |
|---|---|---|---|
| Progesterone receptor | Oryctolagus cuniculus (rabbit) | 5.6 | |
| Progesterone receptor | Homo sapiens (human) | 1.819 | |
| Androgen receptor | Homo sapiens (human) | 0.404 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.7168 | |
| Androgen receptor | Mus musculus (house mouse) | 1.835 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.12 | |
| Progesterone receptor | Rattus norvegicus (Norway rat) | 0.89 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Jung, ME; Ouk, S; Sawyers, CL; Tran, C; Wongvipat, J; Yoo, D | 1 |
| Gim, HJ; Houk, KN; Jung, ME; Park, J | 1 |
2 other study(ies) available for ru 59063 and bicalutamide
| Article | Year |
|---|---|
Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).
Topics: Androgen Receptor Antagonists; Androgens; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Male; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship; Thiohydantoins; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Conformational dynamics of androgen receptors bound to agonists and antagonists.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Benzamides; Binding Sites; Dihydrotestosterone; Humans; Imidazoles; Ligands; Molecular Conformation; Molecular Dynamics Simulation; Nitriles; Phenylthiohydantoin; Principal Component Analysis; Protein Binding; Protein Conformation; Receptors, Androgen; Thiohydantoins; Tosyl Compounds | 2021 |