Page last updated: 2024-09-03

ru 39411 and tamoxifen

ru 39411 has been researched along with tamoxifen in 9 studies

Compound Research Comparison

Studies
(ru 39411)
Trials
(ru 39411)
Recent Studies (post-2010)
(ru 39411)
Studies
(tamoxifen)
Trials
(tamoxifen)
Recent Studies (post-2010) (tamoxifen)
150220,6302,2276,256

Protein Interaction Comparison

ProteinTaxonomyru 39411 (IC50)tamoxifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.46
Serine/threonine-protein kinase D3Homo sapiens (human)1
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)3.553
Estrogen receptorHomo sapiens (human)0.9266
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.949
Protein kinase C gamma typeHomo sapiens (human)1
Protein kinase C beta typeHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)8.033
Tyrosine-protein kinase FynHomo sapiens (human)1.195
Progesterone receptorHomo sapiens (human)0.1288
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.472
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.793
Muscarinic acetylcholine receptor M4Homo sapiens (human)4.817
ATP-dependent translocase ABCB1Homo sapiens (human)6.4
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.585
Alpha-2A adrenergic receptorHomo sapiens (human)1.935
Adenosine receptor A3Homo sapiens (human)3.701
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.829
Steroid hormone receptor ERR1Homo sapiens (human)0.2
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.967
Beta-3 adrenergic receptorHomo sapiens (human)7.703
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.701
Protein kinase C alpha typeHomo sapiens (human)1
Alpha-2B adrenergic receptorHomo sapiens (human)3.518
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.974
Substance-K receptorHomo sapiens (human)3.67
D(1A) dopamine receptorHomo sapiens (human)8.502
Prostaglandin G/H synthase 1Homo sapiens (human)4.391
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.472
Thromboxane-A synthase Homo sapiens (human)0.916
Protein kinase C eta typeHomo sapiens (human)1
Histamine H2 receptorHomo sapiens (human)9.396
Alpha-1D adrenergic receptorHomo sapiens (human)4.982
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.801
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.46
Adenosine receptor A2aHomo sapiens (human)7.099
Sodium-dependent serotonin transporterHomo sapiens (human)2.334
D(3) dopamine receptorHomo sapiens (human)1.072
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.084
Protein kinase C iota typeHomo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)3.701
5-hydroxytryptamine receptor 6Homo sapiens (human)2.679
Estrogen-related receptor gammaHomo sapiens (human)0.0622
Sodium-dependent dopamine transporter Homo sapiens (human)1.841
Protein kinase C epsilon typeHomo sapiens (human)1
Protein kinase C theta typeHomo sapiens (human)1
Protein kinase C zeta typeHomo sapiens (human)1
Protein kinase C delta typeHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.2759
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.904
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)0.012
Serine/threonine-protein kinase D1Homo sapiens (human)1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.967
Estrogen receptor betaHomo sapiens (human)0.7809
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.021
7-dehydrocholesterol reductaseHomo sapiens (human)0.012

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's7 (77.78)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gasc, JM1
Gottardis, MM; Jordan, VC; Ricchio, ME; Satyaswaroop, PG1
Gottardis, MM; Jeng, MH; Jiang, SY; Jordan, VC1
Bouhoute, A; Leclercq, G1
Bardin, CW; Kaplan-Kraicer, R; Kostovetsky, I; Shalgi, R1
Bardin, CW; Dao, B; Koide, SS; Marshall, A; Vanage, G1
Koide, SS; Li, XJ; Yu, H1
Aliau, S; Borgna, JL; Mattras, H; Richard, E1
Aliau, S; Bonnafous, JC; Borgna, JL; Mattras, H; Richard, E1

Other Studies

9 other study(ies) available for ru 39411 and tamoxifen

ArticleYear
Distribution and regulation of progesterone receptor in the urogenital tract of the chick embryo. An immunohistochemical study.
    Anatomy and embryology, 1991, Volume: 183, Issue:4

    Topics: Animals; Chick Embryo; Estradiol; Female; Gonads; Immunohistochemistry; Male; Meninges; Mesonephros; Mullerian Ducts; Receptors, Progesterone; Spinal Cord; Tamoxifen; Up-Regulation; Urogenital System; Wolffian Ducts

1991
Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Animals; Carcinoma; Cell Division; Delayed-Action Preparations; Estradiol; Estrogen Antagonists; Ethamoxytriphetol; Ethanol; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Ovariectomy; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured; Uterine Neoplasms

1990
Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.
    Cancer research, 1989, Aug-01, Volume: 49, Issue:15

    Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polyunsaturated Alkamides; Tamoxifen; Transplantation, Heterologous

1989
Estradiol derivatives bearing the side-chain of tamoxifen antagonize the association between the estrogen receptor and calmodulin.
    Biochemical pharmacology, 1994, Feb-11, Volume: 47, Issue:4

    Topics: Animals; Calmodulin; Estradiol; Estrogen Antagonists; Female; Rats; Receptors, Estrogen; Tamoxifen

1994
Tamoxifen and RU39411 synergize with mifepristone to produce preimplantation pregnancy loss by increasing embryo transport (rat).
    Contraception, 1996, Volume: 53, Issue:6

    Topics: Abortifacient Agents, Steroidal; Administration, Oral; Animals; Blastocyst; Corpus Luteum; Drug Combinations; Drug Synergism; Embryo Implantation; Embryo Loss; Embryonic Development; Estradiol; Estrogen Antagonists; Female; Mifepristone; Pregnancy; Rats; Rats, Wistar; Tamoxifen; Time Factors

1996
Anti-implantation activity of antiestrogens and mifepristone.
    Contraception, 1996, Volume: 54, Issue:4

    Topics: Administration, Oral; Animals; Contraceptives, Postcoital; Embryo Implantation; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Injections, Subcutaneous; Male; Mifepristone; Norandrostanes; Pregnancy; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1996
Effect of mifepristone and antiestrogens on uterine PGF2 alpha and PGE2 concentrations in ovariectomized and pregnant rats.
    Prostaglandins, 1997, Volume: 53, Issue:3

    Topics: Abortifacient Agents, Steroidal; Animals; Contraceptives, Postcoital, Synthetic; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic Development; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Mifepristone; Norandrostanes; Organ Size; Ovariectomy; Pregnancy; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1997
Cysteine 530 of the human estrogen receptor alpha is the main covalent attachment site of 11beta-(aziridinylalkoxyphenyl)estradiols.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Animals; Aziridines; Binding Sites; Binding, Competitive; COS Cells; Cysteine; Estradiol; Estrogen Receptor alpha; Female; Humans; Ligands; Receptors, Estrogen; Sheep; Tamoxifen; Uterus

1999
Differential interactions of estrogens and antiestrogens at the 17 beta-hydroxyl or counterpart hydroxyl with histidine 524 of the human estrogen receptor alpha.
    Biochemistry, 2002, Jun-25, Volume: 41, Issue:25

    Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; COS Cells; Diethyl Pyrocarbonate; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Histidine; Humans; Hydroxyl Radical; Ligands; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen

2002